thalidomide has been researched along with Aseptic Necrosis of Femur Head in 1 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide-treated patients had a prevalence of AVN similar to that of the control group (8% v 10%, respectively; P = ." | 2.71 | Avascular necrosis of femoral and/or humeral heads in multiple myeloma: results of a prospective study of patients treated with dexamethasone-based regimens and high-dose chemotherapy. ( Anaissie, E; Angtuaco, E; Barlogie, B; Dong, L; Miceli, MH; Talamo, G; Tricot, G; Walker, RC; Zangari, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Talamo, G | 1 |
| Angtuaco, E | 1 |
| Walker, RC | 1 |
| Dong, L | 1 |
| Miceli, MH | 1 |
| Zangari, M | 1 |
| Tricot, G | 1 |
| Barlogie, B | 1 |
| Anaissie, E | 1 |
1 trial available for thalidomide and Aseptic Necrosis of Femur Head
| Article | Year |
|---|---|
Avascular necrosis of femoral and/or humeral heads in multiple myeloma: results of a prospective study of patients treated with dexamethasone-based regimens and high-dose chemotherapy.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Female; Fem | 2005 |