thalidomide has been researched along with Arthritis in 17 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Arthritis: Acute or chronic inflammation of JOINTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " After discontinuation of lenalidomide, he had no arthritis relapse; it was then concluded that the patient had a lenalidomide-induced arthritis." | 9.22 | Lenalidomide-induced arthritis: A case report and review of literature and pharmacovigilance databases. ( Despas, F; Gauthier, M; Icard, C; Mocquot, P; Nogaro, JC, 2022) |
| "This study aimed to determine the clinical efficacy of apremilast for oral ulcers (OUs), extra-oral manifestations, and overall disease activity in patients with Behçet's disease (BD)." | 9.22 | Beneficial effects of apremilast on genital ulcers, skin lesions, and arthritis in patients with Behçet's disease: A systematic review and meta-analysis. ( Hirahara, L; Horita, N; Iizuka, Y; Kirino, Y; Mizuki, N; Nakajima, H; Namkoong, HO; Soejima, Y; Takase-Minegishi, K; Takeno, M; Takeuchi, M; Yoshimi, R, 2022) |
| "The present study investigates synergistic effects of the TNF-alpha inhibitor thalidomide and the poly(ADP-ribose) polymerase (PARP)-inhibitor nicotinic acid amide (NAA) in male DBA/1 hybird mice suffering from type II collagen-induced arthritis." | 7.69 | Synergistic effects of thalidomide and poly (ADP-ribose) polymerase inhibition on type II collagen-induced arthritis in mice. ( Dietrich, A; Kröger, H; Miesel, R; Ockenfels, H; Ohde, M; Rajnavölgyi, E, 1996) |
| " After discontinuation of lenalidomide, he had no arthritis relapse; it was then concluded that the patient had a lenalidomide-induced arthritis." | 5.22 | Lenalidomide-induced arthritis: A case report and review of literature and pharmacovigilance databases. ( Despas, F; Gauthier, M; Icard, C; Mocquot, P; Nogaro, JC, 2022) |
| "This study aimed to determine the clinical efficacy of apremilast for oral ulcers (OUs), extra-oral manifestations, and overall disease activity in patients with Behçet's disease (BD)." | 5.22 | Beneficial effects of apremilast on genital ulcers, skin lesions, and arthritis in patients with Behçet's disease: A systematic review and meta-analysis. ( Hirahara, L; Horita, N; Iizuka, Y; Kirino, Y; Mizuki, N; Nakajima, H; Namkoong, HO; Soejima, Y; Takase-Minegishi, K; Takeno, M; Takeuchi, M; Yoshimi, R, 2022) |
| " The efficacy and safety evaluations of several PDE4 inhibitors are currently carried on in clinical trials, for example GSK256066 in asthma, roflumilast and GSK256066 in chronic obstructive pulmonary disease, tetomilast in inflammatory bowel disease, and apremilast in dermatitis and arthritis etc." | 4.90 | [Progress in PDE4 targeted therapy for inflammatory diseases]. ( Song, SD; Tang, HF, 2014) |
| " Thalidomide is effective in reducing the extent of arthritis as well as reducing the seizure scoring and increasing seizure onset in the adjuvant arthritis group." | 3.74 | Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat. ( Arora, SK; Khanduja, KL; Medhi, B; Pandhi, P; Rao, RS; Saikia, UN; Toor, JS, 2008) |
| "The present study investigates synergistic effects of the TNF-alpha inhibitor thalidomide and the poly(ADP-ribose) polymerase (PARP)-inhibitor nicotinic acid amide (NAA) in male DBA/1 hybird mice suffering from type II collagen-induced arthritis." | 3.69 | Synergistic effects of thalidomide and poly (ADP-ribose) polymerase inhibition on type II collagen-induced arthritis in mice. ( Dietrich, A; Kröger, H; Miesel, R; Ockenfels, H; Ohde, M; Rajnavölgyi, E, 1996) |
| " Prednisolone in standard dosage schedule as recommended by WHO is now being widely used in control programmes." | 1.32 | Reactions and their management. ( Ganapati, R; Pai, VV, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (17.65) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 4 (23.53) | 2.80 |
| Authors | Studies |
|---|---|
| da Silva, YK | 1 |
| Augusto, CV | 1 |
| de Castro Barbosa, ML | 1 |
| de Albuquerque Melo, GM | 1 |
| de Queiroz, AC | 1 |
| de Lima Matos Freire Dias, T | 1 |
| Júnior, WB | 1 |
| Barreiro, EJ | 1 |
| Lima, LM | 1 |
| Alexandre-Moreira, MS | 1 |
| Icard, C | 1 |
| Mocquot, P | 1 |
| Nogaro, JC | 1 |
| Despas, F | 1 |
| Gauthier, M | 1 |
| Iizuka, Y | 1 |
| Takase-Minegishi, K | 1 |
| Hirahara, L | 1 |
| Kirino, Y | 1 |
| Soejima, Y | 1 |
| Namkoong, HO | 1 |
| Horita, N | 1 |
| Yoshimi, R | 1 |
| Takeuchi, M | 1 |
| Takeno, M | 1 |
| Mizuki, N | 1 |
| Nakajima, H | 1 |
| Wang, W | 2 |
| Zhong, LQ | 1 |
| Li, WD | 1 |
| Wu, SJ | 1 |
| Song, HM | 1 |
| Takama, H | 1 |
| Ando, Y | 1 |
| Yanagishita, T | 1 |
| Ohshima, Y | 1 |
| Akiyama, M | 1 |
| Watanabe, D | 1 |
| Kikuchi, N | 1 |
| Yamamoto, T | 1 |
| Song, SD | 1 |
| Tang, HF | 1 |
| Cozzani, E | 1 |
| Gasparini, G | 1 |
| Parodi, A | 1 |
| Rao, RS | 1 |
| Medhi, B | 1 |
| Saikia, UN | 1 |
| Arora, SK | 1 |
| Toor, JS | 1 |
| Khanduja, KL | 1 |
| Pandhi, P | 1 |
| Andres, M | 1 |
| Agullo, A | 1 |
| Negrete, R | 1 |
| Batlle, E | 1 |
| Martinez, A | 1 |
| Evans, R | 1 |
| Ganapati, R | 1 |
| Pai, VV | 1 |
| Trèves, R | 1 |
| Arnaud, M | 1 |
| Jacob, P | 1 |
| Lubeau, M | 1 |
| Tabaraud, F | 1 |
| Burki, F | 1 |
| Desproges-Gotteron, R | 1 |
| Kröger, H | 1 |
| Miesel, R | 1 |
| Dietrich, A | 1 |
| Ohde, M | 1 |
| Rajnavölgyi, E | 1 |
| Ockenfels, H | 1 |
| Hauschild, A | 1 |
| Kroeger, H | 1 |
| Mitchison, NA | 1 |
| Ugrinovic, S | 1 |
| Zwingenberger, K | 1 |
| Goihman-Yahr, M | 1 |
| Convit, J | 1 |
| Rodríguez-Ochoa, G | 1 |
| Aranzazu, N | 1 |
| Villalba-Pimentel, L | 1 |
| Ocanto, A | 1 |
| de Gómez, ME | 1 |
| Hamza, MH | 1 |
4 reviews available for thalidomide and Arthritis
| Article | Year |
|---|---|
Lenalidomide-induced arthritis: A case report and review of literature and pharmacovigilance databases.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arthritis; Cyclophosphamide; Doxorubici | 2022 |
Beneficial effects of apremilast on genital ulcers, skin lesions, and arthritis in patients with Behçet's disease: A systematic review and meta-analysis.
Topics: Arthritis; Behcet Syndrome; Genitalia; Humans; Oral Ulcer; Skin Ulcer; Thalidomide; Ulcer | 2022 |
[Progress in PDE4 targeted therapy for inflammatory diseases].
Topics: Aminopyridines; Aminoquinolines; Arthritis; Asthma; Benzamides; Cyclopropanes; Dermatitis; Humans; I | 2014 |
Pyoderma gangrenosum: a systematic review.
Topics: Anti-Inflammatory Agents; Arthritis; Dermatologic Agents; Diagnosis, Differential; Disease Progressi | 2014 |
13 other studies available for thalidomide and Arthritis
| Article | Year |
|---|---|
Synthesis and pharmacological evaluation of pyrazine N-acylhydrazone derivatives designed as novel analgesic and anti-inflammatory drug candidates.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Ear; Edema; Female; Freund's Adjuvant; Hyd | 2010 |
Thalidomide may be an effective drug for Blau syndrome: a case report.
Topics: Arthritis; Female; Humans; Nod2 Signaling Adaptor Protein; Sarcoidosis; Synovitis; Thalidomide; Uvei | 2022 |
Successful treatment of pustulotic arthro-osteitis with apremilast: a case report with follow-up MRI.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Female; Follow-Up Studies; Humans; Magneti | 2019 |
Effects of apremilast on pustulotic arthro-osteitis in a real-world setting: Report of five cases.
Topics: Arthritis; Humans; Osteitis; Psoriasis; Thalidomide | 2020 |
Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat.
Topics: Acetic Acid; Analysis of Variance; Animals; Arthritis; Colitis; Cyclooxygenase Inhibitors; Cytokines | 2008 |
Lepromatous leprosy presenting as an acute polyarthritis in a Colombian immigrant in Spain.
Topics: Acute Disease; Adult; Arthritis; Biopsy; Colombia; Emigration and Immigration; Humans; Leprostatic A | 2012 |
Anti arthritic drugs--SMi conference: dual inhibitors. 28-29 April 2003, London, UK.
Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Arthritis; Clinical Trial | 2003 |
Reactions and their management.
Topics: Arthritis; Cicatrix; Clofazimine; Dose-Response Relationship, Drug; Drug-Related Side Effects and Ad | 2004 |
[Speculative ameloriation of arthritis in Behcet disease with thalidomide. A case report].
Topics: Adult; Arthritis; Behcet Syndrome; Humans; Male; Thalidomide | 1984 |
Synergistic effects of thalidomide and poly (ADP-ribose) polymerase inhibition on type II collagen-induced arthritis in mice.
Topics: Animals; Arthritis; Arthritis, Rheumatoid; Cattle; Collagen; Disease Models, Animal; Drug Synergism; | 1996 |
Thalidomide therapy of established collagen-induced arthritis (CIA) not accompanied by an evident Th2 shift.
Topics: Animals; Arthritis; Collagen; Mice; Mice, Inbred DBA; Th1 Cells; Th2 Cells; Thalidomide; Tumor Necro | 1997 |
Significance of neutrophil activation in reactional lepromatous leprosy: effects of thalidomide in vivo and in vitro. Activation in adjuvant disease.
Topics: Arthritis; Arthritis, Experimental; Leprosy; Lymphocyte Activation; Neutrophils; Thalidomide | 1978 |
Treatment of Behçet's disease with thalidomide.
Topics: Adolescent; Adult; Arthritis; Behcet Syndrome; Humans; Male; Middle Aged; Thalidomide | 1986 |