thalidomide has been researched along with Arteriovenous Malformations in 6 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Arteriovenous Malformations: Abnormal formation of blood vessels that shunt arterial blood directly into veins without passing through the CAPILLARIES. They usually are crooked, dilated, and with thick vessel walls. A common type is the congenital arteriovenous fistula. The lack of blood flow and oxygen in the capillaries can lead to tissue damage in the affected areas.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although epistaxis is usually presented in childhood (mean age 11 ± 7." | 1.48 | Clinical features and treatment of hereditary hemorrhagic telangiectasia. ( Li, S; Wang, SJ; Zhao, YQ, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Namdaran, P | 1 |
| Zikos, TA | 1 |
| Pan, JY | 1 |
| Banerjee, D | 1 |
| Bongetta, D | 1 |
| Zoia, C | 1 |
| Lafe, E | 1 |
| Gaetani, P | 1 |
| Li, S | 1 |
| Wang, SJ | 1 |
| Zhao, YQ | 1 |
| Abrantes, J | 1 |
| Fernandes, C | 1 |
| Vieira, CL | 1 |
| Perez Botero, J | 1 |
| Burns, D | 1 |
| Thompson, CA | 1 |
| Pruthi, RK | 1 |
| Blinc, A | 1 |
| Golli, T | 1 |
| Vodnik, AC | 1 |
| Zver, S | 1 |
6 other studies available for thalidomide and Arteriovenous Malformations
| Article | Year |
|---|---|
Thalidomide Use Reduces Risk of Refractory Gastrointestinal Bleeding in Patients with Continuous Flow Left Ventricular Assist Devices.
Topics: Adult; Aged; Arteriovenous Malformations; Female; Gastrointestinal Hemorrhage; Heart Failure; Heart- | 2020 |
Could Thalidomide Be a Treatment Option for Arteriovenous Malformations?
Topics: Angiogenesis Inhibitors; Arteriovenous Malformations; Humans; Thalidomide | 2017 |
Clinical features and treatment of hereditary hemorrhagic telangiectasia.
Topics: Adult; Angiogenesis Inhibitors; Arteriovenous Malformations; Delayed Diagnosis; Epistaxis; Female; H | 2018 |
Pulmonary arteriovenous malformation in hereditary haemorrhagic telangiectasia.
Topics: Angiogenesis Inhibitors; Argon Plasma Coagulation; Arteriovenous Malformations; Bevacizumab; Endosco | 2019 |
Successful treatment with thalidomide of a patient with congenital factor V deficiency and factor V inhibitor with recurrent gastrointestinal bleeding from small bowel arteriovenous malformations.
Topics: Aged; Angiogenesis Inhibitors; Arteriovenous Malformations; Blood Coagulation Factor Inhibitors; Blo | 2013 |
Concurrent thalidomide and radiation therapy for extensive arterio-venous malformations.
Topics: Angiogenesis Inhibitors; Arm; Arteriovenous Malformations; Combined Modality Therapy; Humans; Male; | 2008 |