thalidomide has been researched along with Arteriosclerosis in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of the current study was to evaluate the effects of thalidomide on graft arteriosclerosis." | 7.77 | Thalidomide attenuates graft arteriosclerosis of aortic transplant in a rat model. ( Cai, Y; Chen, BC; Chen, WW; Xia, P; Yang, M; Yang, Y; Yang, YR; Zhang, Y; Zheng, SL, 2011) |
| "The purpose of the current study was to evaluate the effects of thalidomide on graft arteriosclerosis." | 3.77 | Thalidomide attenuates graft arteriosclerosis of aortic transplant in a rat model. ( Cai, Y; Chen, BC; Chen, WW; Xia, P; Yang, M; Yang, Y; Yang, YR; Zhang, Y; Zheng, SL, 2011) |
| "Mice treated with thalidomide had significantly smaller mean (7986 +/- 5189 vs 19607 +/- 10353 microns 2, p = 0." | 1.32 | Thalidomide inhibits early atherogenesis in apoE-deficient mice. ( Chew, M; Daugherty, A; Ellermann-Eriksen, S; Eriksson, T; Falk, E; Hansen, PR; Zhou, J, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Y | 1 |
| Yang, M | 1 |
| Yang, Y | 1 |
| Zheng, SL | 1 |
| Cai, Y | 1 |
| Xia, P | 1 |
| Chen, WW | 1 |
| Chen, BC | 1 |
| Yang, YR | 1 |
| Chew, M | 1 |
| Zhou, J | 1 |
| Daugherty, A | 1 |
| Eriksson, T | 1 |
| Ellermann-Eriksen, S | 1 |
| Hansen, PR | 1 |
| Falk, E | 1 |
2 other studies available for thalidomide and Arteriosclerosis
| Article | Year |
|---|---|
Thalidomide attenuates graft arteriosclerosis of aortic transplant in a rat model.
Topics: Animals; Aorta; Arteriosclerosis; Blotting, Western; Disease Models, Animal; Enzyme-Linked Immunosor | 2011 |
Thalidomide inhibits early atherogenesis in apoE-deficient mice.
Topics: Animals; Apolipoproteins E; Arteriosclerosis; Disease Models, Animal; Mice; Thalidomide; Tumor Necro | 2003 |