Page last updated: 2024-11-05

thalidomide and Arterial Obstructive Diseases

thalidomide has been researched along with Arterial Obstructive Diseases in 3 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Research Excerpts

ExcerptRelevanceReference
"Thalidomide has been associated with venous thrombotic events, as reported in the post-marketing surveillance reports by Celgene Corporation; as well as case reports in the literature."5.33Arterial thrombosis in four patients treated with thalidomide. ( Brown, K; Chanan-Khan, A; Hahn, T; McCarthy, PL; Paplham, P; Roy, H; Scarpace, SL; van Besien, K, 2005)
"Thalidomide has been associated with venous thrombotic events, as reported in the post-marketing surveillance reports by Celgene Corporation; as well as case reports in the literature."1.33Arterial thrombosis in four patients treated with thalidomide. ( Brown, K; Chanan-Khan, A; Hahn, T; McCarthy, PL; Paplham, P; Roy, H; Scarpace, SL; van Besien, K, 2005)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abe, N1
Tomita, T1
Bohgaki, M1
Kasahara, H1
Koike, T1
Mamopoulos, A1
Nowak, T1
Luther, B1
Scarpace, SL1
Hahn, T1
Roy, H1
Brown, K1
Paplham, P1
Chanan-Khan, A1
van Besien, K1
McCarthy, PL1

Other Studies

3 other studies available for thalidomide and Arterial Obstructive Diseases

ArticleYear
Crystalglobulinemia manifesting as chronic arthralgia and acute limb ischemia: A clinical case report.
    Medicine, 2017, Volume: 96, Issue:16

    Topics: Amputation, Surgical; Arterial Occlusive Diseases; Arthralgia; Bortezomib; Dexamethasone; Humans; Le

2017
Peripheral arterial reconstruction in a patient with thalidomide embryopathy and chronic occlusion of the femoral artery.
    VASA. Zeitschrift fur Gefasskrankheiten, 2013, Volume: 42, Issue:4

    Topics: Abnormalities, Drug-Induced; Antiemetics; Arterial Occlusive Diseases; Chronic Disease; Constriction

2013
Arterial thrombosis in four patients treated with thalidomide.
    Leukemia & lymphoma, 2005, Volume: 46, Issue:2

    Topics: Aged; Arterial Occlusive Diseases; Aspirin; Drug Therapy, Combination; Female; Humans; Intracranial

2005