thalidomide has been researched along with Aqueductal Stenosis in 7 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tuberculous meningitis is a highly morbid, often fatal disease." | 1.48 | Intracranial tuberculous mass lesions treated with thalidomide in an immunocompetent child from a low tuberculosis endemic country: A case report. ( Ajassa, C; Caraffa, E; Ciardi, MR; Lichtner, M; Massetti, AP; Mastroianni, CM; Russo, G; Vita, S; Vullo, V, 2018) |
| "Head anomalies in fetuses (anencephaly, holoprosencephaly and hydrocephaly) were induced at a high frequency by the maternal administration of thalidomide on day 7, and also in a few fetuses on day 8." | 1.27 | [Teratogenic potentially of single dose of thalidomide in JW-NIBS rabbits]. ( Matsubara, Y; Mikami, T, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Caraffa, E | 1 |
| Russo, G | 1 |
| Vita, S | 1 |
| Lichtner, M | 1 |
| Massetti, AP | 1 |
| Mastroianni, CM | 1 |
| Vullo, V | 1 |
| Ciardi, MR | 1 |
| Ajassa, C | 1 |
| INGALLS, TH | 1 |
| KLINGBERG, MA | 1 |
| Matsubara, Y | 1 |
| Mikami, T | 1 |
| Bryan, EM | 1 |
| Kohler, HG | 1 |
| Pearn, JH | 1 |
| Vickers, TH | 1 |
| Aeppli, L | 1 |
1 review available for thalidomide and Aqueductal Stenosis
| Article | Year |
|---|---|
CONGENITAL MALFORMATIONS. CLINICAL AND COMMUNITY CONSIDERATIONS.
Topics: Abnormalities, Drug-Induced; Abnormalities, Severe Teratoid; Achondroplasia; Anencephaly; Cleft Pala | 1965 |
6 other studies available for thalidomide and Aqueductal Stenosis
| Article | Year |
|---|---|
Intracranial tuberculous mass lesions treated with thalidomide in an immunocompetent child from a low tuberculosis endemic country: A case report.
Topics: Antitubercular Agents; Brain; Cerebrospinal Fluid; Child; Female; Glucocorticoids; Humans; Hydroceph | 2018 |
[THE INCIDENCE OF DEFORMITIES OF THE EXTREMITIES IN HAMBURG IN THE YEARS 1960 TO 1962].
Topics: Abnormalities, Drug-Induced; Abnormalities, Severe Teratoid; Ear Deformities, Acquired; Ear, Externa | 1963 |
[Teratogenic potentially of single dose of thalidomide in JW-NIBS rabbits].
Topics: Abnormalities, Drug-Induced; Anencephaly; Animals; Brain; Female; Heart Defects, Congenital; Hydroce | 1985 |
The missing umbilical artery. I. Prospective study based on a maternity unit.
Topics: Adult; Anencephaly; Birth Weight; Congenital Abnormalities; Female; Gestational Age; Humans; Hydroce | 1974 |
The rabbit thalidomide embryopathy.
Topics: Abnormalities, Drug-Induced; Animals; Biliary Tract; Digestive System Abnormalities; Eye Abnormaliti | 1966 |
[Teratologic studies with imipramine in rats and rabbits. Planning and interpretation of teratologic studies under consideration of the biochemistry and toxicology of test substance].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Body Weight; Desipramine; Drug Toleranc | 1969 |