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thalidomide and Angiitis

thalidomide has been researched along with Angiitis in 9 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Research Excerpts

ExcerptRelevanceReference
"Thalidomide is used for the acute treatment and suppression of the cutaneous manifestations of erythema nodosum leprosum (ENL)."7.75Thalidomide levels in patients with erythema nodosum leprosum. ( Valente, Mdo S; Vieira, JL, 2009)
"We found that thalidomide, through its antiinflammatory and antiproliferative effects, significantly inhibits neointimal hyperplasia in balloon-injured rat carotid arteries."7.72Thalidomide as a potent inhibitor of neointimal hyperplasia after balloon injury in rat carotid artery. ( Chae, IH; Choi, DJ; Jeon, SI; Kim, DH; Kim, HS; Koo, BK; Lee, MM; Oh, BH; Park, KW; Park, SJ; Park, YB; Yang, HM; Youn, SW, 2004)
"Thalidomide therapy was started for four patients with significant morbidity from Behçet's syndrome and for one patient with bowel-associated dermatosis-arthritis syndrome."5.27Thalidomide effects in Behçet's syndrome and pustular vasculitis. ( Cavallo, T; Daniels, JC; Jorizzo, JL; Rudloff, HB; Schmalstieg, EJ; Schmalstieg, FC; Solomon, AR; Taylor, RS, 1986)
"Thalidomide is used for the acute treatment and suppression of the cutaneous manifestations of erythema nodosum leprosum (ENL)."3.75Thalidomide levels in patients with erythema nodosum leprosum. ( Valente, Mdo S; Vieira, JL, 2009)
"We found that thalidomide, through its antiinflammatory and antiproliferative effects, significantly inhibits neointimal hyperplasia in balloon-injured rat carotid arteries."3.72Thalidomide as a potent inhibitor of neointimal hyperplasia after balloon injury in rat carotid artery. ( Chae, IH; Choi, DJ; Jeon, SI; Kim, DH; Kim, HS; Koo, BK; Lee, MM; Oh, BH; Park, KW; Park, SJ; Park, YB; Yang, HM; Youn, SW, 2004)
"Thalidomide is a synthetic glutamic acid derivative first introduced in 1956 in Germany as an over the counter medications."2.50[Current therapeutic indications of thalidomide and lenalidomide]. ( Cosiglio, FJ; Ordi-Ros, J, 2014)
"Thalidomide therapy was started for four patients with significant morbidity from Behçet's syndrome and for one patient with bowel-associated dermatosis-arthritis syndrome."1.27Thalidomide effects in Behçet's syndrome and pustular vasculitis. ( Cavallo, T; Daniels, JC; Jorizzo, JL; Rudloff, HB; Schmalstieg, EJ; Schmalstieg, FC; Solomon, AR; Taylor, RS, 1986)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ordi-Ros, J1
Cosiglio, FJ1
Baek, MC1
Jung, B1
Kang, H1
Lee, HS1
Bae, JS1
Hatemi, I1
Hatemi, G1
Çelik, AF1
Vieira, JL1
Valente, Mdo S1
Francès, C1
Barete, S1
Ayoub, N1
Piette, JC1
SCHULZ, KH1
JAENNER, M1
Park, SJ1
Kim, HS1
Yang, HM1
Park, KW1
Youn, SW1
Jeon, SI1
Kim, DH1
Koo, BK1
Chae, IH1
Choi, DJ1
Oh, BH1
Lee, MM1
Park, YB1
Silingardi, M1
Iotti, M1
Trenti, C1
Salvarani, C1
Iori, I1
Jorizzo, JL1
Schmalstieg, FC1
Solomon, AR1
Cavallo, T1
Taylor, RS1
Rudloff, HB1
Schmalstieg, EJ1
Daniels, JC1

Reviews

3 reviews available for thalidomide and Angiitis

ArticleYear
[Current therapeutic indications of thalidomide and lenalidomide].
    Medicina clinica, 2014, Apr-22, Volume: 142, Issue:8

    Topics: Abnormalities, Drug-Induced; Anti-Inflammatory Agents; Antineoplastic Agents; Collagen Diseases; End

2014
Novel insight into drug repositioning: Methylthiouracil as a case in point.
    Pharmacological research, 2015, Volume: 99

    Topics: Animals; Anti-Inflammatory Agents; Antithyroid Agents; Arthritis, Rheumatoid; Biomarkers; Doxycyclin

2015
Systemic vasculitis and the gut.
    Current opinion in rheumatology, 2017, Volume: 29, Issue:1

    Topics: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Behcet Syndrome; Cyclophosphamide; Gastr

2017

Other Studies

6 other studies available for thalidomide and Angiitis

ArticleYear
Thalidomide levels in patients with erythema nodosum leprosum.
    Therapeutic drug monitoring, 2009, Volume: 31, Issue:5

    Topics: Adult; Chromatography, Liquid; Erythema Nodosum; Humans; Leprostatic Agents; Leprosy, Lepromatous; M

2009
[Classification of dermatologic manifestations in lupus erythematosus].
    Annales de medecine interne, 2003, Volume: 154, Issue:1

    Topics: Acitretin; Adrenal Cortex Hormones; Adult; Antimalarials; Clinical Trials as Topic; Dapsone; Dermato

2003
[ALLERGIC VASCULITIS WITH THROMBOCYTOPENIA CAUSED BY THALIDOMIDE].
    Allergie und Asthma, 1963, Volume: 9

    Topics: Arteritis; Drug Hypersensitivity; Exanthema; Leg; Phlebitis; Purpura; Purpura, Thrombocytopenic; Tha

1963
Thalidomide as a potent inhibitor of neointimal hyperplasia after balloon injury in rat carotid artery.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carotid Arteries; Carotid Stenosis; Catheterizatio

2004
Thalidomide, deep venous thrombosis and vasculitis.
    Journal of thrombosis and haemostasis : JTH, 2004, Volume: 2, Issue:11

    Topics: Aged; Female; Humans; Lupus Erythematosus, Systemic; Thalidomide; Vasculitis; Venous Thrombosis

2004
Thalidomide effects in Behçet's syndrome and pustular vasculitis.
    Archives of internal medicine, 1986, Volume: 146, Issue:5

    Topics: Antigen-Antibody Complex; Behcet Syndrome; Cell Line; Cell Migration Inhibition; Glycoproteins; Memb

1986