thalidomide has been researched along with Aneurysm, Anterior Cerebral Artery in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cerebral aneurysms were induced through hypertension and a single stereotactic injection of elastase into the basal cistern in mice." | 1.40 | Critical role of TNF-α in cerebral aneurysm formation and progression to rupture. ( Chalouhi, N; Dumont, AS; Gonzalez, LF; Greig, NH; Hasan, DM; Jabbour, PM; Owens, GK; Rosenwasser, RH; Shimada, K; Starke, RM; Tjoumakaris, SI; Wada, K, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ali, MS | 1 |
| Starke, RM | 2 |
| Jabbour, PM | 2 |
| Tjoumakaris, SI | 2 |
| Gonzalez, LF | 2 |
| Rosenwasser, RH | 2 |
| Owens, GK | 2 |
| Koch, WJ | 1 |
| Greig, NH | 2 |
| Dumont, AS | 2 |
| Chalouhi, N | 1 |
| Wada, K | 1 |
| Shimada, K | 1 |
| Hasan, DM | 1 |
2 other studies available for thalidomide and Aneurysm, Anterior Cerebral Artery
| Article | Year |
|---|---|
TNF-α induces phenotypic modulation in cerebral vascular smooth muscle cells: implications for cerebral aneurysm pathology.
Topics: Animals; Apoptosis; Carotid Arteries; Cell Differentiation; Cells, Cultured; Circle of Willis; Disea | 2013 |
Critical role of TNF-α in cerebral aneurysm formation and progression to rupture.
Topics: Aneurysm, Ruptured; Animals; Blood Pressure; Blood Vessels; Disease Models, Animal; Disease Progress | 2014 |