thalidomide has been researched along with Allergy, Drug in 23 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide appears to be a safe and effective alternative for short-term healing in patients who develop infliximab-induced delayed hypersensitivity reaction and may be an alternative strategy for those at risk." | 6.70 | Thalidomide as "salvage" therapy for patients with delayed hypersensitivity response to infliximab: a case series. ( Ehrenpreis, E; Kane, S; Stone, LJ, 2002) |
| "Pomalidomide is an immunomodulating agent that is used to treat relapsed and/or refractory multiple myeloma." | 3.96 | Pomalidomide desensitization for hypersensitivity: A case report. ( Cooper, DL; Huang, E; Kane, MP; Monteleone, CA; Park, JJ, 2020) |
| "Lenalidomide is a new immunomodulatory drug, FDA-approved for the treatment of the 5q-myelodysplastic syndrome and refractory or relapsed multiple myeloma (MM)." | 3.76 | A case of lenalidomide-induced hypersensitivity pneumonitis. ( Feilchenfeldt, J; Györik, S; Lerch, E; Mazzucchelli, L; Quadri, F, 2010) |
| "Thalidomide appears to be a safe and effective alternative for short-term healing in patients who develop infliximab-induced delayed hypersensitivity reaction and may be an alternative strategy for those at risk." | 2.70 | Thalidomide as "salvage" therapy for patients with delayed hypersensitivity response to infliximab: a case series. ( Ehrenpreis, E; Kane, S; Stone, LJ, 2002) |
| "Thalidomide has immunomodulatory and anti-tumor necrosis factor-α effects as well as antiangiogenic properties, making it useful for a broad spectrum of inflammatory disorders." | 2.52 | Review of thalidomide use in the pediatric population. ( Antaya, RJ; Kim, C; Yang, CS, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (47.83) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 3 (13.04) | 29.6817 |
| 2010's | 6 (26.09) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Park, JJ | 1 |
| Huang, E | 1 |
| Monteleone, CA | 1 |
| Kane, MP | 1 |
| Cooper, DL | 1 |
| Grandoni, F | 1 |
| Stalder, G | 1 |
| Borgeat Kaeser, A | 1 |
| Ribi, C | 1 |
| Cairoli, A | 1 |
| Blum, S | 1 |
| Lee, MJ | 1 |
| Wickner, P | 1 |
| Fanning, L | 1 |
| Schlossman, R | 1 |
| Richardson, P | 1 |
| Laubach, J | 1 |
| Castells, M | 1 |
| Yang, CS | 1 |
| Kim, C | 1 |
| Antaya, RJ | 1 |
| Nucera, E | 1 |
| Schiavino, D | 1 |
| Hohaus, S | 1 |
| Leone, G | 1 |
| Buonomo, A | 1 |
| Lombardo, C | 1 |
| Patriarca, G | 1 |
| Kortuem, M | 1 |
| Einsele, H | 1 |
| Lerch, E | 1 |
| Györik, S | 1 |
| Feilchenfeldt, J | 1 |
| Mazzucchelli, L | 1 |
| Quadri, F | 1 |
| Seki, JT | 1 |
| Banglawala, S | 1 |
| Lentz, EM | 1 |
| Reece, DE | 1 |
| Kane, S | 1 |
| Stone, LJ | 1 |
| Ehrenpreis, E | 1 |
| SKRE, H | 1 |
| DIMITRIU, CG | 1 |
| SCHULZ, KH | 1 |
| JAENNER, M | 1 |
| MOTULSKY, AG | 1 |
| KEEFER, CS | 1 |
| MAIER, W | 1 |
| Phillips, J | 1 |
| Kujawa, J | 1 |
| Davis-Lorton, M | 1 |
| Hindenburg, A | 1 |
| Dyban, AP | 1 |
| Akimova, IM | 1 |
| Matsuzawa, T | 1 |
| Ramanujam, K | 1 |
| Iyer, CG | 1 |
| Ramu, G | 1 |
| Williams, I | 1 |
| Weller, IV | 1 |
| Malni, A | 1 |
| Anderson, J | 1 |
| Waters, MF | 1 |
| Keplinger, ML | 1 |
| Fancher, OE | 1 |
| Lyman, FL | 1 |
| Calandra, JC | 1 |
| Modell, W | 1 |
| Schuppli, R | 1 |
3 reviews available for thalidomide and Allergy, Drug
| Article | Year |
|---|---|
Review of thalidomide use in the pediatric population.
Topics: Abnormalities, Drug-Induced; Adolescent; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Au | 2015 |
PHARMACOGENETICS.
Topics: Abnormalities, Drug-Induced; Animals; Dicumarol; Dogs; Drug Hypersensitivity; Drug Tolerance; Ethnol | 1964 |
Issues and problems regarding the prediction of delayed side-effects (toxicity) of pharmaceutical compounds.
Topics: Animals; Clioquinol; Drug Evaluation, Preclinical; Drug Hypersensitivity; Drug-Related Side Effects | 1996 |
2 trials available for thalidomide and Allergy, Drug
| Article | Year |
|---|---|
Thalidomide as "salvage" therapy for patients with delayed hypersensitivity response to infliximab: a case series.
Topics: Adult; Antibodies, Monoclonal; Crohn Disease; Drug Hypersensitivity; Female; Follow-Up Studies; Huma | 2002 |
Open trial with clofazimine in the management of recurrent lepra reaction and of sulphone sensitive cases: a preliminary report.
Topics: Adult; Clinical Trials as Topic; Clofazimine; Drug Hypersensitivity; Humans; Leprosy; Male; Sulfones | 1975 |
18 other studies available for thalidomide and Allergy, Drug
| Article | Year |
|---|---|
Pomalidomide desensitization for hypersensitivity: A case report.
Topics: Aged; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Immunologic Factors; Mult | 2020 |
Successful desensitization to pomalidomide in a patient with POEMS syndrome with delayed-type hypersensitivity to immunomodulatory imid drugs.
Topics: Aged; Biomarkers; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Hypersensitiv | 2019 |
Lenalidomide desensitization for delayed hypersensitivity reactions in 5 patients with multiple myeloma.
Topics: Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; Immu | 2014 |
Desensitization to thalidomide in a patient with multiple myeloma.
Topics: Aged; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Immunosuppressive Agents; | 2008 |
Lenalidomide-induced hypersensitivity pneumonitis.
Topics: Adrenal Cortex Hormones; Aged; Alveolitis, Extrinsic Allergic; Antineoplastic Agents; Antineoplastic | 2010 |
A case of lenalidomide-induced hypersensitivity pneumonitis.
Topics: Aged; Alveolitis, Extrinsic Allergic; Antineoplastic Agents; Diagnosis, Differential; Drug Hypersens | 2010 |
Desensitization to lenalidomide in a patient with relapsed multiple myeloma.
Topics: Antineoplastic Agents; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Lenalidomide; Ma | 2013 |
[THALIDOMIDE POLYNEURITIS: A FORM OF RIBOFLAVIN AVITAMINOSIS?].
Topics: Avitaminosis; Dermatology; Drug Hypersensitivity; Edema; Folic Acid; Geriatrics; Headache; Neuritis; | 1963 |
[THE SECONDARY EFFECTS OF MODERN MEDICAMENTS].
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Anticoagulants; Antihypertensive Agents; Antithy | 1963 |
[ALLERGIC VASCULITIS WITH THROMBOCYTOPENIA CAUSED BY THALIDOMIDE].
Topics: Arteritis; Drug Hypersensitivity; Exanthema; Leg; Phlebitis; Purpura; Purpura, Thrombocytopenic; Tha | 1963 |
DIAGNOSIS AND TREATMENT OF UNWANTED REACTIONS TO DRUGS.
Topics: Abnormalities, Drug-Induced; Drug Hypersensitivity; Humans; Thalidomide; Toxicology | 1964 |
[OUR CURRENT KNOWLEDGE ON EXTERNAL INJURIOUS INFLUENCES ON THE EMBRYO AND CONGENITAL DEFECTS].
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Drug Hypersensitivity; Knowledge; Thalidomide | 1964 |
Successful desensitization in a patient with lenalidomide hypersensitivity.
Topics: Adult; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Lenalidomide; Multiple M | 2007 |
[The significance of group B vitamins and genetic factors on the reaction of the rat embryo to thalidomide].
Topics: Abnormalities, Drug-Induced; Abnormalities, Severe Teratoid; Animals; Diet; Drug Hypersensitivity; E | 1966 |
Thalidomide hypersensitivity in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Drug Hypersensitivity; Humans; Male; Stomatitis, Aphthous; Thali | 1991 |
Toxicologic studies of four fluorescent whitening agents.
Topics: Abnormalities, Drug-Induced; Animals; Dogs; Dose-Response Relationship, Drug; Drug Hypersensitivity; | 1974 |
Mass drug catastrophes and the roles of science and technology.
Topics: Alcoholism; Caffeine; Cannabis; Central Nervous System; Cocaine; Drug Hypersensitivity; Hallucinogen | 1967 |
[Results of modern therapy of leprosy].
Topics: Communicable Disease Control; Drug Hypersensitivity; Humans; Leprosy; Sulfathiazoles; Sulfonamides; | 1969 |