thalidomide has been researched along with Alcoholism in 10 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment options for alcohol use disorders (AUDs) have minimally advanced since 2004, while the annual deaths and economic toll have increased alarmingly." | 3.30 | Preclinical and clinical evidence for suppression of alcohol intake by apremilast. ( Aziz, HC; Becker, HC; Beneze, A; Bess, J; Crabbe, JC; Eisenstein, TK; Firsick, EJ; Grigsby, KB; Light, JM; Lopez, MF; Mangieri, RA; Mason, BJ; Meissler, JJ; Metten, P; Miller, J; Morrisett, RA; Ozburn, AR; Quello, S; Roberto, M; Roberts, AJ; Shadan, F; Skinner, M; Townsley, KG, 2023) |
| "Cases with documented maternal alcohol abuse in pregnancy in this group were analyzed separately." | 1.28 | Congenital defects of the limbs and alcohol exposure in pregnancy: data from a population based study. ( Baird, PA; Froster, UG, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grigsby, KB | 1 |
| Mangieri, RA | 1 |
| Roberts, AJ | 1 |
| Lopez, MF | 1 |
| Firsick, EJ | 1 |
| Townsley, KG | 1 |
| Beneze, A | 1 |
| Bess, J | 1 |
| Eisenstein, TK | 1 |
| Meissler, JJ | 1 |
| Light, JM | 1 |
| Miller, J | 1 |
| Quello, S | 1 |
| Shadan, F | 1 |
| Skinner, M | 1 |
| Aziz, HC | 1 |
| Metten, P | 1 |
| Morrisett, RA | 1 |
| Crabbe, JC | 1 |
| Roberto, M | 1 |
| Becker, HC | 1 |
| Mason, BJ | 1 |
| Ozburn, AR | 1 |
| MILLER, JM | 1 |
| GINSBERG, M | 1 |
| MCELFATRICK, GC | 1 |
| SHONBERG, IL | 1 |
| Cooper, SJ | 1 |
| Rennert, OM | 1 |
| Harris, JM | 1 |
| Pashayan, HM | 1 |
| Froster, UG | 1 |
| Baird, PA | 1 |
| Liebaldt, GP | 1 |
| Broser, F | 1 |
| O'Sullivan, DJ | 1 |
| Swallow, M | 1 |
| Lister, J | 1 |
| Modell, W | 1 |
1 review available for thalidomide and Alcoholism
| Article | Year |
|---|---|
Drug-induced somatic alterations.
Topics: Abnormalities, Drug-Induced; Alcoholism; Animals; Anticonvulsants; Cannabis; Environmental Exposure; | 1975 |
1 trial available for thalidomide and Alcoholism
| Article | Year |
|---|---|
Preclinical and clinical evidence for suppression of alcohol intake by apremilast.
Topics: Alcohol Drinking; Alcoholism; Animals; Ethanol; Humans; Mice; Phosphodiesterase 4 Inhibitors; Psoria | 2023 |
8 other studies available for thalidomide and Alcoholism
| Article | Year |
|---|---|
The use of contergan-268 in the treatment of the withdrawal syndrome in chronic alcoholism.
Topics: Alcoholism; Anesthesia; Humans; Hypnotics and Sedatives; Substance Withdrawal Syndrome; Thalidomide | 1960 |
Poisoned people: psychotropic drugs in pregnancy: morphological and psychological adverse effects on offspring.
Topics: Abnormalities, Drug-Induced; Alcoholism; Behavior; Female; Fetal Alcohol Spectrum Disorders; Fetus; | 1978 |
Teratogenesis.
Topics: Abnormalities, Drug-Induced; Alcoholism; Aminopterin; Animals; Anticonvulsants; Dose-Response Relati | 1976 |
Congenital defects of the limbs and alcohol exposure in pregnancy: data from a population based study.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Alcoholism; Animals; British Columbia; Cocaine | 1992 |
[What is the relevance of various previous lesions of the peripheral nervous system to a thalidomide polyneuropathy?].
Topics: Adult; Alcoholism; Autopsy; Diagnosis, Differential; Humans; Male; Muscles; Peripheral Nerves; Polyn | 1971 |
The fibre size and content of the radial and sural nerves.
Topics: Adolescent; Adult; Age Factors; Aged; Alcoholism; Extremities; Female; Humans; Male; Middle Aged; My | 1968 |
Disabled children--free contraception for all? More liberal liquor laws?
Topics: Abnormalities, Drug-Induced; Adult; Alcoholism; Child; Contraception; Family Planning Services; Fema | 1973 |
Mass drug catastrophes and the roles of science and technology.
Topics: Alcoholism; Caffeine; Cannabis; Central Nervous System; Cocaine; Drug Hypersensitivity; Hallucinogen | 1967 |