thalidomide has been researched along with Alcohol Drinking in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment options for alcohol use disorders (AUDs) have minimally advanced since 2004, while the annual deaths and economic toll have increased alarmingly." | 3.30 | Preclinical and clinical evidence for suppression of alcohol intake by apremilast. ( Aziz, HC; Becker, HC; Beneze, A; Bess, J; Crabbe, JC; Eisenstein, TK; Firsick, EJ; Grigsby, KB; Light, JM; Lopez, MF; Mangieri, RA; Mason, BJ; Meissler, JJ; Metten, P; Miller, J; Morrisett, RA; Ozburn, AR; Quello, S; Roberto, M; Roberts, AJ; Shadan, F; Skinner, M; Townsley, KG, 2023) |
| "Apremilast is a selective PDE4 inhibitor with fewer gastrointestinal side effects that is FDA-approved for the treatment of psoriasis." | 1.48 | Apremilast Alters Behavioral Responses to Ethanol in Mice: I. Reduced Consumption and Preference. ( Blednov, YA; Da Costa, AJ; Harris, RA; Messing, RO; Ponomareva, O; Tarbox, T, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Grigsby, KB | 1 |
| Mangieri, RA | 1 |
| Roberts, AJ | 1 |
| Lopez, MF | 1 |
| Firsick, EJ | 1 |
| Townsley, KG | 1 |
| Beneze, A | 1 |
| Bess, J | 1 |
| Eisenstein, TK | 1 |
| Meissler, JJ | 1 |
| Light, JM | 1 |
| Miller, J | 1 |
| Quello, S | 1 |
| Shadan, F | 1 |
| Skinner, M | 1 |
| Aziz, HC | 1 |
| Metten, P | 1 |
| Morrisett, RA | 1 |
| Crabbe, JC | 1 |
| Roberto, M | 1 |
| Becker, HC | 1 |
| Mason, BJ | 1 |
| Ozburn, AR | 1 |
| Kalisch-Smith, JI | 1 |
| Ved, N | 1 |
| Sparrow, DB | 1 |
| Blednov, YA | 1 |
| Da Costa, AJ | 1 |
| Tarbox, T | 1 |
| Ponomareva, O | 1 |
| Messing, RO | 1 |
| Harris, RA | 1 |
1 review available for thalidomide and Alcohol Drinking
| Article | Year |
|---|---|
Environmental Risk Factors for Congenital Heart Disease.
Topics: Alcohol Drinking; Animals; Diabetes Mellitus; Environmental Exposure; Gene-Environment Interaction; | 2020 |
1 trial available for thalidomide and Alcohol Drinking
| Article | Year |
|---|---|
Preclinical and clinical evidence for suppression of alcohol intake by apremilast.
Topics: Alcohol Drinking; Alcoholism; Animals; Ethanol; Humans; Mice; Phosphodiesterase 4 Inhibitors; Psoria | 2023 |
1 other study available for thalidomide and Alcohol Drinking
| Article | Year |
|---|---|
Apremilast Alters Behavioral Responses to Ethanol in Mice: I. Reduced Consumption and Preference.
Topics: Alcohol Drinking; Animals; Brain; Choice Behavior; Ethanol; Female; Food Preferences; Liver; Male; M | 2018 |