thalidomide has been researched along with Alcohol Abuse in 10 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment options for alcohol use disorders (AUDs) have minimally advanced since 2004, while the annual deaths and economic toll have increased alarmingly." | 3.30 | Preclinical and clinical evidence for suppression of alcohol intake by apremilast. ( Aziz, HC; Becker, HC; Beneze, A; Bess, J; Crabbe, JC; Eisenstein, TK; Firsick, EJ; Grigsby, KB; Light, JM; Lopez, MF; Mangieri, RA; Mason, BJ; Meissler, JJ; Metten, P; Miller, J; Morrisett, RA; Ozburn, AR; Quello, S; Roberto, M; Roberts, AJ; Shadan, F; Skinner, M; Townsley, KG, 2023) |
| "Cases with documented maternal alcohol abuse in pregnancy in this group were analyzed separately." | 1.28 | Congenital defects of the limbs and alcohol exposure in pregnancy: data from a population based study. ( Baird, PA; Froster, UG, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grigsby, KB | 1 |
| Mangieri, RA | 1 |
| Roberts, AJ | 1 |
| Lopez, MF | 1 |
| Firsick, EJ | 1 |
| Townsley, KG | 1 |
| Beneze, A | 1 |
| Bess, J | 1 |
| Eisenstein, TK | 1 |
| Meissler, JJ | 1 |
| Light, JM | 1 |
| Miller, J | 1 |
| Quello, S | 1 |
| Shadan, F | 1 |
| Skinner, M | 1 |
| Aziz, HC | 1 |
| Metten, P | 1 |
| Morrisett, RA | 1 |
| Crabbe, JC | 1 |
| Roberto, M | 1 |
| Becker, HC | 1 |
| Mason, BJ | 1 |
| Ozburn, AR | 1 |
| MILLER, JM | 1 |
| GINSBERG, M | 1 |
| MCELFATRICK, GC | 1 |
| SHONBERG, IL | 1 |
| Cooper, SJ | 1 |
| Rennert, OM | 1 |
| Harris, JM | 1 |
| Pashayan, HM | 1 |
| Froster, UG | 1 |
| Baird, PA | 1 |
| Liebaldt, GP | 1 |
| Broser, F | 1 |
| O'Sullivan, DJ | 1 |
| Swallow, M | 1 |
| Lister, J | 1 |
| Modell, W | 1 |
1 review available for thalidomide and Alcohol Abuse
| Article | Year |
|---|---|
Drug-induced somatic alterations.
Topics: Abnormalities, Drug-Induced; Alcoholism; Animals; Anticonvulsants; Cannabis; Environmental Exposure; | 1975 |
1 trial available for thalidomide and Alcohol Abuse
| Article | Year |
|---|---|
Preclinical and clinical evidence for suppression of alcohol intake by apremilast.
Topics: Alcohol Drinking; Alcoholism; Animals; Ethanol; Humans; Mice; Phosphodiesterase 4 Inhibitors; Psoria | 2023 |
8 other studies available for thalidomide and Alcohol Abuse
| Article | Year |
|---|---|
The use of contergan-268 in the treatment of the withdrawal syndrome in chronic alcoholism.
Topics: Alcoholism; Anesthesia; Humans; Hypnotics and Sedatives; Substance Withdrawal Syndrome; Thalidomide | 1960 |
Poisoned people: psychotropic drugs in pregnancy: morphological and psychological adverse effects on offspring.
Topics: Abnormalities, Drug-Induced; Alcoholism; Behavior; Female; Fetal Alcohol Spectrum Disorders; Fetus; | 1978 |
Teratogenesis.
Topics: Abnormalities, Drug-Induced; Alcoholism; Aminopterin; Animals; Anticonvulsants; Dose-Response Relati | 1976 |
Congenital defects of the limbs and alcohol exposure in pregnancy: data from a population based study.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Alcoholism; Animals; British Columbia; Cocaine | 1992 |
[What is the relevance of various previous lesions of the peripheral nervous system to a thalidomide polyneuropathy?].
Topics: Adult; Alcoholism; Autopsy; Diagnosis, Differential; Humans; Male; Muscles; Peripheral Nerves; Polyn | 1971 |
The fibre size and content of the radial and sural nerves.
Topics: Adolescent; Adult; Age Factors; Aged; Alcoholism; Extremities; Female; Humans; Male; Middle Aged; My | 1968 |
Disabled children--free contraception for all? More liberal liquor laws?
Topics: Abnormalities, Drug-Induced; Adult; Alcoholism; Child; Contraception; Family Planning Services; Fema | 1973 |
Mass drug catastrophes and the roles of science and technology.
Topics: Alcoholism; Caffeine; Cannabis; Central Nervous System; Cocaine; Drug Hypersensitivity; Hallucinogen | 1967 |