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thalidomide and Aggressive Natural Killer Cell Leukemia

thalidomide has been researched along with Aggressive Natural Killer Cell Leukemia in 2 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Research Excerpts

ExcerptRelevanceReference
"Both T-cell and NK-cell LGL leukemia can manifest as indolent or aggressive neoplasia."1.39Very long-lasting remission of refractory T-large granular lymphocytes leukemia and myeloma by lenalidomide treatment. ( Alma, E; Cox, MC; Di Napoli, A; Naso, V; Pelliccia, S; Rebecchini, C, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pelliccia, S1
Di Napoli, A1
Naso, V1
Alma, E1
Rebecchini, C1
Cox, MC1
Cheng, J1
Talamo, G1
Malysz, J1
Ochmann, M1
Lamy, T1
Loughran, TP1

Other Studies

2 other studies available for thalidomide and Aggressive Natural Killer Cell Leukemia

ArticleYear
Very long-lasting remission of refractory T-large granular lymphocytes leukemia and myeloma by lenalidomide treatment.
    European journal of haematology, 2013, Volume: 91, Issue:2

    Topics: Antineoplastic Agents; Bone Marrow; Boronic Acids; Bortezomib; Humans; Lenalidomide; Leukemia, Large

2013
Report of 6 cases of large granular lymphocytic leukemia and plasma cell dyscrasia.
    Clinical lymphoma, myeloma & leukemia, 2014, Volume: 14, Issue:5

    Topics: Aged; Aged, 80 and over; Anemia; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Proto

2014