Page last updated: 2024-11-05

thalidomide and Acute Pain

thalidomide has been researched along with Acute Pain in 1 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Acute Pain: Intensely discomforting, distressful, or agonizing sensation associated with trauma or disease, with well-defined location, character, and timing.

Research Excerpts

ExcerptRelevanceReference
"Thalidomide (5-50mg/kg) was intraperitoneally administered immediately after laparotomy."1.46Thalidomide alleviates postoperative pain and spatial memory deficit in aged rats. ( Guo, P; Hu, SP, 2017)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guo, P1
Hu, SP1

Other Studies

1 other study available for thalidomide and Acute Pain

ArticleYear
Thalidomide alleviates postoperative pain and spatial memory deficit in aged rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 95

    Topics: Acute Pain; Aging; Animals; Cytokines; Inflammation Mediators; Locomotion; Male; Memory Disorders; P

2017