thalidomide has been researched along with Acute Hepatic Failure in 4 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reed-Guy, L | 1 |
| Hoteit, MA | 1 |
| Garfall, AL | 1 |
| Jain, P | 1 |
| Hamadani, M | 1 |
| Benson, DM | 1 |
| Copelan, EA | 1 |
| Liu, S | 1 |
| Zheng, M | 1 |
| Li, Z | 1 |
| Yu, Z | 1 |
| Lu, H | 1 |
1 review available for thalidomide and Acute Hepatic Failure
| Article | Year |
|---|---|
Lenalidomide-induced acute liver failure.
Topics: Adenine; Aged, 80 and over; Antineoplastic Agents; Antiviral Agents; Hepatitis B, Chronic; Humans; L | 2009 |
3 other studies available for thalidomide and Acute Hepatic Failure
| Article | Year |
|---|---|
Acute Liver Failure Associated With Pomalidomide Therapy for Multiple Myeloma.
Topics: Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Humans; Liver Failure, Acute; Liver F | 2018 |
Thalidomide-induced fulminant hepatic failure.
Topics: Fatal Outcome; Female; Humans; Immunosuppressive Agents; Liver Failure, Acute; Middle Aged; Multiple | 2007 |
[The protective effects of thalidomide on acute liver failure].
Topics: Animals; Galactosamine; Immunosuppressive Agents; Lipopolysaccharides; Liver Failure, Acute; Male; R | 1999 |