Page last updated: 2024-11-05

thalidomide and Acquired Autoimmune Hemolytic Anemia

thalidomide has been researched along with Acquired Autoimmune Hemolytic Anemia in 9 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Research Excerpts

ExcerptRelevanceReference
" The diagnosis of multiple myeloma and Evan's syndrome was made, we underwent chemotherapy by BTD (bortezomib-thalidomide-dexamethasone) and continuous corticosteroid therapy but unfortunately the patient died secondary of a Lactic acidosis."3.83Multiple myeloma associated with an Evan's syndrome. ( Abderrahim, K; Amina, BB; Asma, A; Bechir, A; Emna, B; Haifa, R; Mondher, K; Mrabet, S; Nesrine, BS; Senda, M; Yosra, BY, 2016)
"One patient developed autoimmune hemolytic anemia and another grade 4 thrombocytopenia."2.87Lenalidomide as immune adjuvant to a dendritic cell vaccine in chronic lymphocytic leukemia patients. ( Adamson, L; Eriksson, I; Gentilcore, G; Hansson, L; Heimersson, K; Mellstedt, H; Mozaffari, F; Mulder, TA; Näsman-Glaser, B; Österborg, A; Palma, M; Ryblom, H; Svensson, A, 2018)
"Lenalidomide is an amino-substituted analog of thalidomide with potent immunomodulatory properties."1.38Plasma exchange and rituximab treatment for lenalidomide-associated cold agglutinin disease. ( Akpek, G; Brauer, DL; Edelman, B; Hess, JR; Rapoport, AP, 2012)
"Autoimmune haemolytic anaemia is also recognised, is frequently difficult to treat and overall prognosis is often poor, usually from associated problems."1.31Remission of severe, intractable autoimmune haemolytic anaemia following matched unrelated donor transplantation. ( Kinsey, SE; Pratt, G, 2001)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's6 (66.67)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Wu, Y1
Yang, K1
Kong, W1
Xiao, J1
Liu, X1
Palma, M1
Hansson, L1
Mulder, TA1
Adamson, L1
Näsman-Glaser, B1
Eriksson, I1
Heimersson, K1
Ryblom, H1
Mozaffari, F1
Svensson, A1
Gentilcore, G1
Österborg, A1
Mellstedt, H1
Fattizzo, B1
Zaninoni, A1
Nesa, F1
Sciumbata, VM1
Zanella, A1
Cortelezzi, A1
Barcellini, W1
Chic Acevedo, C1
García Torres, E1
Álvarez Rivas, MÁ1
Bechir, A1
Haifa, R1
Nesrine, BS1
Emna, B1
Senda, M1
Asma, A1
Amina, BB1
Mrabet, S1
Yosra, BY1
Mondher, K1
Abderrahim, K1
Sun, WL1
Köck, L1
Walder, A1
Erdel, M1
Kilga-Nogler, S1
Schennach, H1
Fiegl, M1
Brauer, DL1
Edelman, B1
Rapoport, AP1
Hess, JR1
Akpek, G1
Darabi, K1
Kantamnei, S1
Wiernik, PH1
Pratt, G1
Kinsey, SE1

Trials

1 trial available for thalidomide and Acquired Autoimmune Hemolytic Anemia

ArticleYear
Lenalidomide as immune adjuvant to a dendritic cell vaccine in chronic lymphocytic leukemia patients.
    European journal of haematology, 2018, Volume: 101, Issue:1

    Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; A

2018

Other Studies

8 other studies available for thalidomide and Acquired Autoimmune Hemolytic Anemia

ArticleYear
Thalidomide-associated autoimmune hemolytic anemia.
    Pediatric blood & cancer, 2023, Volume: 70, Issue:4

    Topics: Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Humans; Thalidomide

2023
Lessons from very severe, refractory, and fatal primary autoimmune hemolytic anemias.
    American journal of hematology, 2015, Volume: 90, Issue:8

    Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal, Murine-Derived; Erythrocytes; Hemolysis; Huma

2015
[Cold agglutinin disease of IgA class as early manifestation of multiple myeloma and resolution after treatment with new anti-myeloma drugs].
    Medicina clinica, 2016, Dec-02, Volume: 147, Issue:11

    Topics: Anemia, Hemolytic, Autoimmune; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols

2016
Multiple myeloma associated with an Evan's syndrome.
    The Pan African medical journal, 2016, Volume: 25

    Topics: Acidosis, Lactic; Adrenal Cortex Hormones; Anemia, Hemolytic, Autoimmune; Antineoplastic Combined Ch

2016
Successful treatment of MDS with lenalidomide, complicated by transient autoimmune hemolysis.
    Annals of hematology, 2010, Volume: 89, Issue:3

    Topics: Anemia, Hemolytic, Autoimmune; Antineoplastic Agents; Female; Humans; Immunoglobulins; Lenalidomide;

2010
Plasma exchange and rituximab treatment for lenalidomide-associated cold agglutinin disease.
    Transfusion, 2012, Volume: 52, Issue:11

    Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Combin

2012
Lenalidomide-induced warm autoimmune hemolytic anemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Dec-10, Volume: 24, Issue:35

    Topics: Aged; Anemia, Hemolytic, Autoimmune; Female; Humans; Lenalidomide; Lymphoma, B-Cell; Thalidomide

2006
Remission of severe, intractable autoimmune haemolytic anaemia following matched unrelated donor transplantation.
    Bone marrow transplantation, 2001, Volume: 28, Issue:8

    Topics: Adrenal Cortex Hormones; Alemtuzumab; Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal; Antibod

2001