thalidomide has been researched along with Acantholysis in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Acantholysis: Separation of the prickle cells of the stratum spinosum of the epidermis, resulting in atrophy of the prickle cell layer. It is seen in diseases such as pemphigus vulgaris (see PEMPHIGUS) and DARIER DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide (Tha) can be used as a selective treatment for mild pemphigus vulgaris (PV)." | 8.31 | Thalidomide Alleviates Apoptosis, Oxidative Damage and Inflammation Induced by Pemphigus Vulgaris IgG in HaCat Cells and Neonatal Mice Through MyD88. ( Chen, J; Chen, M; Li, X; Lu, Z; Luan, C; Zhao, R, 2023) |
| "Thalidomide (Tha) can be used as a selective treatment for mild pemphigus vulgaris (PV)." | 4.31 | Thalidomide Alleviates Apoptosis, Oxidative Damage and Inflammation Induced by Pemphigus Vulgaris IgG in HaCat Cells and Neonatal Mice Through MyD88. ( Chen, J; Chen, M; Li, X; Lu, Z; Luan, C; Zhao, R, 2023) |
| "In cases of malignancy that are refractive to treatment, other therapies have been found to be effective for paraneoplastic itch, including selective serotonin reuptake inhibitors, mirtazapine, gabapentin, thalidomide, opioids, aprepitant, and histone deacetylase inhibitors." | 2.53 | Paraneoplastic Itch Management. ( Rowe, B; Yosipovitch, G, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luan, C | 1 |
| Lu, Z | 1 |
| Chen, J | 1 |
| Chen, M | 1 |
| Zhao, R | 1 |
| Li, X | 1 |
| Rowe, B | 1 |
| Yosipovitch, G | 1 |
1 review available for thalidomide and Acantholysis
| Article | Year |
|---|---|
Paraneoplastic Itch Management.
Topics: Acantholysis; Acanthosis Nigricans; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Apre | 2016 |
1 other study available for thalidomide and Acantholysis
| Article | Year |
|---|---|
Thalidomide Alleviates Apoptosis, Oxidative Damage and Inflammation Induced by Pemphigus Vulgaris IgG in HaCat Cells and Neonatal Mice Through MyD88.
Topics: Acantholysis; Animals; Animals, Newborn; Apoptosis; bcl-2-Associated X Protein; Caspase 3; HaCaT Cel | 2023 |