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thalidomide and Abscess, Tubercular, Intracranial

thalidomide has been researched along with Abscess, Tubercular, Intracranial in 3 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Research Excerpts

ExcerptRelevanceReference
"Thalidomide was introduced as an immunomodulatory adjunct and subsequently the patient made a complete neurological recovery."1.32The use of thalidomide in the treatment of intracranial tuberculomas in adults: two case reports. ( Carmichael, A; Lever, AM; Mendelson, M; Meyer, P; Roberts, MT, 2003)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Roberts, MT1
Mendelson, M2
Meyer, P1
Carmichael, A1
Lever, AM1
Schoeman, JF2
Fieggen, G1
Seller, N1
Hartzenberg, B1
Ravenscroft, A1
Hartzenberg, HB1

Other Studies

3 other studies available for thalidomide and Abscess, Tubercular, Intracranial

ArticleYear
The use of thalidomide in the treatment of intracranial tuberculomas in adults: two case reports.
    The Journal of infection, 2003, Volume: 47, Issue:3

    Topics: Adult; Female; Humans; Immunosuppressive Agents; Thalidomide; Treatment Outcome; Tuberculoma, Intrac

2003
Intractable intracranial tuberculous infection responsive to thalidomide: report of four cases.
    Journal of child neurology, 2006, Volume: 21, Issue:4

    Topics: Arachnoiditis; Blindness; Brain; Child; Child, Preschool; Disease Progression; Drug Therapy, Combina

2006
Possible role of adjunctive thalidomide therapy in the resolution of a massive intracranial tuberculous abscess.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2001, Volume: 17, Issue:6

    Topics: Antitubercular Agents; Combined Modality Therapy; Drug Therapy, Combination; Humans; Infant; Magneti

2001