thalidomide has been researched along with Abortion, Spontaneous in 13 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Abortion, Spontaneous: Expulsion of the product of FERTILIZATION before completing the term of GESTATION and without deliberate interference.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide had no adverse effects on mating and fertility in male and female rabbits dosed up to 500 and 100 mg/kg/day, respectively, for 14 days prior to mating." | 1.32 | Effects of thalidomide on reproductive function and early embryonic development in male and female New Zealand white rabbits. ( Denny, KH; Hoberman, AM; Morseth, SL; Stirling, DI; Teo, SK; Thomas, SD, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (92.31) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HAUPT, H | 1 |
| MARIN-PADILLA, M | 1 |
| BENIRSCHKE, K | 1 |
| Teo, SK | 1 |
| Denny, KH | 1 |
| Stirling, DI | 1 |
| Thomas, SD | 1 |
| Morseth, SL | 1 |
| Hoberman, AM | 1 |
| Hendrickx, AG | 1 |
| Helm, FC | 1 |
| Holtzman, NA | 1 |
| Khoury, MJ | 1 |
| Bore, PJ | 1 |
| Scothorne, RJ | 1 |
| Wilson, JG | 1 |
| Kajii, T | 2 |
| Kida, M | 2 |
| Takahashi, K | 2 |
| Kozaczenko, J | 1 |
| Aeppli, L | 1 |
| Töndury, G | 1 |
| James, WH | 1 |
3 reviews available for thalidomide and Abortion, Spontaneous
| Article | Year |
|---|---|
Monitoring for congenital malformations.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Birth Certificates; England; Environmental Healt | 1986 |
Abnormalities of intrauterine development in non-human primates.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Abortion, Spontaneous; Animals; Antineoplastic | 1972 |
[Effect of drugs, ingested by the mother during pregnancy, on the fetus].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Caffeine; Female; Humans; Meclizine; Pregnancy; | 1969 |
10 other studies available for thalidomide and Abortion, Spontaneous
| Article | Year |
|---|---|
[Nil nocere: Roentgen examination in pregnancy after thalidomide use?].
Topics: Abortion, Induced; Abortion, Spontaneous; Abortion, Therapeutic; Congenital Abnormalities; Female; H | 1962 |
THALIDOMIDE INDUCED ALTERATIONS IN THE BLASTOCYST AND PLACENTA OF THE ARMADILLO, DASYPUS NOVEMCINCTUS MEXICANUS, INCLUDING A CHORIOCARCINOMA.
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Abortion, Spontaneous; Abortion, Veterinary; Animals | 1963 |
Effects of thalidomide on reproductive function and early embryonic development in male and female New Zealand white rabbits.
Topics: Aborted Fetus; Abortion, Spontaneous; Animals; Body Weight; Cesarean Section; Embryonic and Fetal De | 2004 |
Nonteratogenicity of a structural analog of thalidomide in pregnant baboons (Papio cynocephalus).
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Drug Evaluation, Preclinical; Female; P | 1980 |
Effect of thalidomide on survival of skin homografts in rabbits.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Female; Immunosuppressive Agents; Pregn | 1966 |
The effect of thalidomide intake during 113 human pregnancies.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Female; Gestational Age; Humans; Japan; Pregnanc | 1973 |
Thalidomide and critical period. Prescription for 113 pregnant women in a maternity.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Child; Female; Fetal Death; Fetus; Follow-Up Stu | 1973 |
[Teratologic studies with imipramine in rats and rabbits. Planning and interpretation of teratologic studies under consideration of the biochemistry and toxicology of test substance].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Body Weight; Desipramine; Drug Toleranc | 1969 |
[The genesis of congenital malformations].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Antineoplastic Agents; Cell Division; C | 1967 |
Teratogenetic properties of thalidomide.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Female; Humans; Pregnancy; Thalidomide | 1965 |