thalidomide has been researched along with Abnormalities, Drug-Induced in 774 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to assess psychological/psychiatric problems and quality of life (QOL) in patients with thalidomide embryopathy (TE), with a specific focus on pain, including pain severity and the effects of coping strategies for pain." | 7.96 | Quality of life and pain in patients with thalidomide embryopathy in Japan. ( Hinoshita, F; Imai, K; Nakano, Y; Otomo, K; Sone, H, 2020) |
| "Earlier studies have shown that individuals with thalidomide embryopathy can have skeletal deformities, ear and eye aberrations, and facial palsy." | 7.78 | Facial palsy in individuals with thalidomide embryopathy: frequency and characteristics. ( Kiliaridis, S; Sjögreen, L, 2012) |
| "The case history of a fifteen year old patient with Thalidomide induced malformation who developed a lymphoma of high malignancy is presented." | 7.66 | [Coincidence of a thalidomide-induced malformation and a lymphoma of high malignancy (author's transl)]. ( Horwitz, A; Kosenow, W; Miller, A; Schmidt, CG, 1980) |
| "Thalidomide (TD) displays remarkable species specificity, causing birth defects (teratogenesis) in humans and rabbits, but not rats or mice; yet, few determinants of species susceptibility have been identified." | 5.37 | Resistance of CD-1 and ogg1 DNA repair-deficient mice to thalidomide and hydrolysis product embryopathies in embryo culture. ( Gonçalves, LL; Lee, CJ; Wells, PG, 2011) |
| "Celgene has developed and operated pregnancy prevention programs since 1998 with the first approval of thalidomide in the US." | 4.87 | Managing the teratogenic risk of thalidomide and lenalidomide: an industry perspective. ( Bwire, R; Freeman, J; Houn, F, 2011) |
| "The widely accepted standard therapy for cutaneous sarcoidosis includes corticosteroids, antimalarials, and methotrexate." | 4.84 | Cutaneous sarcoidosis therapy updated. ( Badgwell, C; Rosen, T, 2007) |
| "The difficulties in assessing the teratogenic potential of drugs used during pregnancy have been made evident by experiences with thalidomide and diethylstilbestrol (DES)." | 4.76 | In vivo assessment of the teratogenic potential of drugs in humans. ( Stern, L, 1981) |
| "The aim of this study was to assess psychological/psychiatric problems and quality of life (QOL) in patients with thalidomide embryopathy (TE), with a specific focus on pain, including pain severity and the effects of coping strategies for pain." | 3.96 | Quality of life and pain in patients with thalidomide embryopathy in Japan. ( Hinoshita, F; Imai, K; Nakano, Y; Otomo, K; Sone, H, 2020) |
| "Between 1957 and 1962 thalidomide was used as a nonaddictive, nonbarbiturate sedative that also was successful in relieving the symptoms of morning sickness in early pregnancy." | 3.85 | "The legacy of thalidomide" - A multidisciplinary meeting held at the University of York, United Kingdom, on September 30, 2016. ( Atkin, K; Newbronner, E; Vargesson, N, 2017) |
| "We analyzed the frequency of births with phenotypes consistent with thalidomide embryopathy (TEP) and correlated this with the distribution of thalidomide and the prevalence of leprosy between 2005 and 2010 in Brazil." | 3.81 | Pharmacoepidemiology and thalidomide embryopathy surveillance in Brazil. ( Camey, SA; de Lyra Rabello Neto, D; de Oliveira, MZ; Lopez-Camelo, J; Morelo, EF; Sales Luiz Vianna, F; Sanseverino, MT; Schuler-Faccini, L, 2015) |
| "Earlier studies have shown that individuals with thalidomide embryopathy can have skeletal deformities, ear and eye aberrations, and facial palsy." | 3.78 | Facial palsy in individuals with thalidomide embryopathy: frequency and characteristics. ( Kiliaridis, S; Sjögreen, L, 2012) |
| "Fifty years ago several thousand children were born with severe limb defects after their mothers had been given thalidomide in pregnancy." | 3.78 | The penumbra of thalidomide, the litigation culture and the licensing of pharmaceuticals. ( Lachmann, PJ, 2012) |
| "Thalidomide was a widely used drug in the late 1950s and early 1960s for the treatment of nausea in pregnant women." | 3.77 | Thalidomide: the tragedy of birth defects and the effective treatment of disease. ( Kim, JH; Scialli, AR, 2011) |
| "Autism spectrum disorder has been reported in two conditions with known early pregnancy exposure to the teratogenic agents thalidomide and misoprostol." | 3.72 | Autism with ophthalmologic malformations: the plot thickens. ( Bandim, JM; Gillberg, C; Johansson, M; Miller, MT; Strömland, K; Ventura, L, 2004) |
| "The common group of anomalies noted in both cases of thalidomide embryopathy and Möbius sequence suggests that brain-stem damage probably early in embryogenesis can sometimes be associated with autism." | 3.70 | The puzzle of autism: an ophthalmologic contribution. ( Gillberg, C; Johansson, M; Miller, MT; Nilsson, EW; Strömland, K, 1998) |
| "Thalidomide, mainly used for the treatment of leprosy, is a current teratogen in South America, and it is reasonable to assume that at present this situation is affecting many births in underdeveloped countries." | 3.69 | Thalidomide, a current teratogen in South America. ( Ashton-Prolla, P; Barreda-Mejia, E; Brunoni, D; Castilla, EE; Cavalcanti, DP; Correa-Neto, J; Delgadillo, JL; Dutra, MG; Felix, T; Giraldo, A; Juarez, N; Lopez-Camelo, JS; Nazer, J; Orioli, IM; Paz, JE; Pessoto, MA; Pina-Neto, JM; Quadrelli, R; Rittler, M; Rueda, S; Saltos, M; Sánchez, O; Schüler, L, 1996) |
| "A case of thalidomide syndrome diagnosed by ultrasound in the 17th week of pregnancy is presented." | 3.67 | Prenatal diagnosis of thalidomide syndrome. ( Eigier, A; Gollop, TR; Guidugli Neto, J, 1987) |
| "5 ml dimethylformamide (DMF) on day 10, 11, or 12 of the pregnancy." | 3.66 | Embryotoxicity and teratogenicity of thalidomide in rats. ( Parkhie, M; Webb, M, 1983) |
| "The case history of a fifteen year old patient with Thalidomide induced malformation who developed a lymphoma of high malignancy is presented." | 3.66 | [Coincidence of a thalidomide-induced malformation and a lymphoma of high malignancy (author's transl)]. ( Horwitz, A; Kosenow, W; Miller, A; Schmidt, CG, 1980) |
| " Animal models of hemifacial microsomia and thalidomide-induced otomandibular dysostosis are described; the causal mechanism of malformation appeared to be closely related to the formation of a hematoma at the time of development of the stapedial arterial systems." | 3.65 | Hemorrhage in development of the face. ( Poswillo, D, 1975) |
| "On Day 1 of pregnancy, a thalidomide suspension (." | 3.65 | Responses of pre-implantation mouse embryos to thalidomide exposure in utero. ( Batra, BK; Palayoor, T; Raveendran, P, 1976) |
| "Data are presented on 115 children, including three sets of twins, born in Canada in 1961 and 1962 with congenital malformations associated with the use of thalidomide by their mothers in early pregnancy." | 3.64 | CANADIAN THALIDOMIDE EXPERIENCE. ( WEBB, JF, 1963) |
| "Thalidomide is a known sensory neurotoxin in adults." | 2.61 | Thalidomide and neurotrophism. ( Bonar, SF; McCredie, J; O'Sullivan, DJ; Soper, JR; Willert, HG, 2019) |
| "Thalidomide is a teratogen that affects many organs but primarily induces limb truncations like phocomelia." | 2.55 | The Molecular Mechanisms of Thalidomide Teratogenicity and Implications for Modern Medicine. ( Jungck, D; Knobloch, J; Koch, A, 2017) |
| "Thalidomide has immunomodulatory and anti-tumor necrosis factor-α effects as well as antiangiogenic properties, making it useful for a broad spectrum of inflammatory disorders." | 2.52 | Review of thalidomide use in the pediatric population. ( Antaya, RJ; Kim, C; Yang, CS, 2015) |
| "New thalidomide analogues have been developed but lack clinical experience." | 2.50 | [Current therapeutic indications of thalidomide and lenalidomide]. ( Cosiglio, FJ; Ordi-Ros, J, 2014) |
| "Environmental causes of birth defects have increasingly been recognized since the mid-20th century." | 2.47 | Causes of birth defects: lessons from history. ( Lancaster, PA, 2011) |
| "We found that Duane syndrome and its variants were prominent in individuals who were exposed to thalidomide early in the sensitive period (days 20 to 26±)." | 2.47 | What can we learn from the thalidomide experience: an ophthalmologic perspective. ( Miller, MT; Strömland, KK, 2011) |
| "Thalidomide is a very potent teratogen capable of causing severe systemic malformations if the fetus is exposed during the sensitive period." | 2.45 | Thalidomide and misoprostol: Ophthalmologic manifestations and associations both expected and unexpected. ( Miller, MT; Strömland, K; Ventura, L, 2009) |
| "Most reported cases are associated with Duane syndrome." | 2.44 | Congenital aberrant tearing: a re-look. ( Miller, MT; Strömland, K; Ventura, L, 2008) |
| " The latter limit the long-term use of thalidomide and imply strict rules for its prescription and surveillance (efficient contraception, clinical neurological examinations, electroneurophysiological controls)." | 2.42 | [Management of a patient receiving thalidomide]. ( Brocvielle, H; Humbert, P; Kantelip, JP; Muret, P; Plenat, E, 2003) |
| "Thalidomide has proven to be effective in the treatment of erythema nodosum leprosum and aphthous stomatitis." | 2.41 | [Thalidomide--a dreaded drug with new indications]. ( Seidel, C; Waage, A, 2001) |
| "Thalidomide has been used in cases of Behçet's disease with some success." | 2.41 | Thalidomide in Behçet's disease. ( Lim, DL; Shek, LP, 2002) |
| "Important determinants or principles in developmental toxicology are: (1) genotype; (2) developmental stage when an insult is hitting; (3) mechanisms of action; (4) pharmacokinetics of the drug in the mother, conceptus and the neonate; (5) the manifestations of embryo/foeto- and neonatal toxicity such as death, malformations, growth inhibition and functional disturbances; and (6) dose-effect and dose-response relationships." | 2.40 | Susceptibility in utero and upon neonatal exposure. ( Dencker, L; Eriksson, P, 1998) |
| "For a baby with bilateral lower phocomelia, a special "sitting socket" was devised to enable sitting in an upright position." | 2.36 | Review of the treatment of thalidomide children with limb defeciency in Great Britain. ( Fletcher, I, 1980) |
| "Thalidomide is a drug used worldwide for several indications, but the molecular mechanisms of its teratogenic property are not fully understood." | 1.48 | Genetic susceptibility to thalidomide embryopathy in humans: Study of candidate development genes. ( Fraga, LR; Gomes, JDA; Kowalski, TW; Sanseverino, MTV; Schuler-Faccini, L; Tovo-Rodrigues, L; Vianna, FSL, 2018) |
| "Thalidomide-treated embryos with the human CYP3A gene cluster showed limb abnormalities, and human CYP3A was expressed in the placenta, suggesting that human CYP3A in the placenta may contribute to the teratogenicity of thalidomide." | 1.43 | Thalidomide-induced limb abnormalities in a humanized CYP3A mouse model. ( Abe, S; Akita, M; Kamataki, T; Kazuki, K; Kazuki, Y; Kobayashi, K; Ohta, R; Osaki, M; Oshimura, M; Satoh, D; Takehara, S; Yamazaki, H, 2016) |
| "Thalidomide is a known teratogen and it is estimated that more than ten thousand babies were affected by thalidomide embryopathy (TE), which is characterized mainly by limb defects, but can involve many organs and systems." | 1.42 | Thalidomide embryopathy: Follow-up of cases born between 1959 and 2010. ( Kowalski, TW; Sanseverino, MT; Schuler-Faccini, L; Vianna, FS, 2015) |
| " The post-implantation loss rate and number of placental remnants were increased and the number of live fetuses was decreased in both of the strains in the EFD study and in Kbl:NZW at 300 mg/kg dosed on GD 7-8 in the SP study." | 1.40 | Common nature in the effects of thalidomide on embryo-fetal development in Kbl:JW and Kbl:NZW rabbits. ( Awatsuji, H; Kawamura, Y; Matsumoto, K; Sato, K; Shirotsuka, Y, 2014) |
| "Thalidomide (TD) displays remarkable species specificity, causing birth defects (teratogenesis) in humans and rabbits, but not rats or mice; yet, few determinants of species susceptibility have been identified." | 1.37 | Resistance of CD-1 and ogg1 DNA repair-deficient mice to thalidomide and hydrolysis product embryopathies in embryo culture. ( Gonçalves, LL; Lee, CJ; Wells, PG, 2011) |
| "Thalidomide was used before its target cell or mode of action were known." | 1.35 | History, heresy and radiology in scientific discovery. ( McCredie, J, 2009) |
| "Lenalidomide (Revlimid) is an immunomodulatory drug and an analogue of thalidomide, a known teratogen." | 1.35 | RevAssist: a comprehensive risk minimization programme for preventing fetal exposure to lenalidomide. ( Brandenburg, NA; Bwire, R; Castaneda, CP; Freeman, J; Quigley, C; Zeldis, JB, 2008) |
| "In all studies, thalidomide was selectively toxic to development." | 1.34 | Evaluation of the developmental toxicity of lenalidomide in rabbits. ( Christian, MS; Hoberman, A; Laskin, OL; Latriano, L; Sharper, V; Stirling, DI, 2007) |
| "Thalidomide has a potent immunomodulatory property and has now a number of approved and off-label uses in dermatologic, oncologic, infectious and gastrointestinal conditions." | 1.34 | New cases of thalidomide embryopathy in Brazil. ( Castilla, EE; de Sousa, AC; Luna, E; Maximino, C; Schuler-Faccini, L; Schwartz, IV; Soares, RC; Waldman, C, 2007) |
| "The present study determined effects of thalidomide on three successive generations of New Zealand White rabbits after oral dosing to F0 maternal rabbits during the later third of gestation (post major organogenesis) and lactation." | 1.32 | Effects of thalidomide on developmental, peri- and postnatal function in female New Zealand white rabbits and offspring. ( Denny, KH; Hoberman, AM; Morseth, S; Stirling, DI; Teo, SK; Thomas, SD, 2004) |
| "It is confirmed that phocomelia is not an intercalary defect." | 1.32 | The classification of phocomelia. ( Hooper, G; Tytherleigh-Strong, G, 2003) |
| "Thalidomide was found to bind at the N-terminal domain of N-cadherin mimicking a tryptophan residue which is critical for the homodimerization of the adhesion molecule." | 1.31 | A possible role of N-cadherin in thalidomide teratogenicity. ( Eger, K; Hauschildt, S; Hofmann, HJ; Naumann, WW; Thiele, A; Thormann, M, 2000) |
| "In addition, it failed to induce chromosome aberrations in grasshopper neuroblasts when tested in the presence and absence of Aroclor-induced rat liver S9 mix." | 1.30 | Thalidomide: lack of mutagenic activity across phyla and genetic endpoints. ( Ashby, J; Callander, RD; Clay, P; Ferguson, MJ; Galloway, SM; Gaulden, ME; Greenwood, SK; Hill, RB; Kimber, I; Nivard, M; Parry, JM; Tinwell, H; Vogel, E; Williamson, J, 1997) |
| "Thalidomide has also prompted commentators to celebrate American drug regulation and the American liability system; Professor Bernstein argues that these paeans are exaggerated." | 1.30 | Formed by thalidomide: mass torts as a false cure for toxic exposure. ( Bernstein, A, 1997) |
| "Thalidomide is a drug associated with devastating side effects." | 1.30 | Thalidomide's long and winding road. ( Hanna, L, 1998) |
| "This case report describes phantom limbs in four adults with congenital limb deficiency." | 1.29 | Phantom limb experiences in congenital limb-deficient adults. ( Melzack, R; Saadah, ES, 1994) |
| "The dose-response of the teratogenic potency of the thalidomide (Thd) derivative EM12 was evaluated in the common marmoset (Callithrix jacchus)." | 1.29 | Embryotoxic effects of thalidomide derivatives in the non-human primate callithrix jacchus. IV. Teratogenicity of micrograms/kg doses of the EM12 enantiomers. ( Felies, A; Heger, W; Klug, S; Merker, HJ; Nau, H; Neubert, D; Schmahl, HJ, 1994) |
| "Cases with documented maternal alcohol abuse in pregnancy in this group were analyzed separately." | 1.28 | Congenital defects of the limbs and alcohol exposure in pregnancy: data from a population based study. ( Baird, PA; Froster, UG, 1992) |
| "After surgical removal of the meningocele all bladder and rectal disorders disappeared." | 1.28 | [Presacral meningocele in thalidomide-induced embryopathy]. ( Bröcheler, J; Halfmann, R, 1990) |
| "To evaluate the patterns of birth defects associated with diabetic embryopathy, a sensitivity-specificity analysis was performed on 4929 infants with major defects ascertained by the population-based Metropolitan Atlanta Congenital Defects Program between 1968 and 1980." | 1.28 | Clinical-epidemiologic assessment of pattern of birth defects associated with human teratogens: application to diabetic embryopathy. ( Becerra, JE; Cordero, JF; Erickson, JD; Khoury, MJ, 1989) |
| "For example, in the case of Congenital rubella syndrome (CRS), monitoring for the combination of cataracts with deafness and/or patent ductus arteriosus could have led to earlier detection of an epidemic than could monitoring for cataracts alone." | 1.27 | Monitoring for multiple malformations in the detection of epidemics of birth defects. ( Adams, MM; Erickson, JD; Khoury, MJ; Rhodes, P, 1987) |
| "Head anomalies in fetuses (anencephaly, holoprosencephaly and hydrocephaly) were induced at a high frequency by the maternal administration of thalidomide on day 7, and also in a few fetuses on day 8." | 1.27 | [Teratogenic potentially of single dose of thalidomide in JW-NIBS rabbits]. ( Matsubara, Y; Mikami, T, 1985) |
| "The Metropolitan Atlanta Congenital Defects Programme (MACDP) is an intensive surveillance system using several methods to identify infants born with birth defects in the Atlanta area." | 1.26 | Congenital malformations surveillance: two American systems. ( Edmonds, LD; Erickson, JD; Flynt, JW; James, LM; Layde, PM; Oakley, GP, 1981) |
| "A case of aortic regurgitation observed in a thalidomide deformed child is presented." | 1.26 | Congenital aortic regurgitation observed in a thalidomide-deformed child. ( Ando, J; Kobayashi, T; Sato, R; Yasuda, H, 1978) |
| "Thalidomide was administered to pregnant rabbits in dosages of 150-250 mg/kg/day on days 8-12 of gestation." | 1.26 | Studies of the etiology of thalidomide dysmorphogenesis. ( McBride, WG, 1976) |
| "Goiter is relatively common in infants whose mothers were treated with propylthiouracil and other antithyroid drugs, yet they usually show normal thyroid function." | 1.25 | Human experiences related to adverse drug reactions to the fetus or neonate from some maternally administered drugs. ( Shirkey, HC, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 603 (77.91) | 18.7374 |
| 1990's | 63 (8.14) | 18.2507 |
| 2000's | 49 (6.33) | 29.6817 |
| 2010's | 55 (7.11) | 24.3611 |
| 2020's | 4 (0.52) | 2.80 |
| Authors | Studies |
|---|---|
| Passarge, E | 2 |
| Farr, S | 1 |
| Jesus, SM | 1 |
| Santana, RS | 1 |
| Leite, SN | 1 |
| Imai, K | 2 |
| Sone, H | 1 |
| Otomo, K | 1 |
| Nakano, Y | 1 |
| Hinoshita, F | 1 |
| Newbronner, E | 1 |
| Vargesson, N | 5 |
| Atkin, K | 1 |
| Knobloch, J | 1 |
| Jungck, D | 1 |
| Koch, A | 1 |
| Ghassemi Jahani, SA | 1 |
| Danielsson, A | 1 |
| Karlsson, J | 1 |
| Brisby, H | 1 |
| Gomes, JDA | 1 |
| Kowalski, TW | 3 |
| Fraga, LR | 2 |
| Tovo-Rodrigues, L | 2 |
| Sanseverino, MTV | 1 |
| Schuler-Faccini, L | 6 |
| Vianna, FSL | 1 |
| Soper, JR | 1 |
| Bonar, SF | 1 |
| O'Sullivan, DJ | 1 |
| McCredie, J | 17 |
| Willert, HG | 2 |
| Samel, C | 1 |
| Albus, C | 1 |
| Nippert, I | 1 |
| Niecke, A | 1 |
| Lüngen, M | 1 |
| Pfaff, H | 1 |
| Peters, KM | 1 |
| Schulte-Wissermann, H | 2 |
| Parsa, CF | 1 |
| Robert, MP | 1 |
| Hoyt, CS | 1 |
| Mamopoulos, A | 1 |
| Nowak, T | 1 |
| Luther, B | 1 |
| Ordi-Ros, J | 1 |
| Cosiglio, FJ | 1 |
| Howland, RH | 1 |
| Kawamura, Y | 2 |
| Shirotsuka, Y | 1 |
| Awatsuji, H | 1 |
| Matsumoto, K | 2 |
| Sato, K | 2 |
| Yamashita, T | 1 |
| Yamauchi, T | 1 |
| Iida, T | 1 |
| Yamamoto, M | 1 |
| Komatsu, K | 1 |
| Nukui, Y | 1 |
| Yoshizawa, A | 2 |
| Kouros, N | 1 |
| Cuello-Garcia, CA | 1 |
| Hui, JY | 1 |
| Hoffmann, M | 1 |
| Kumar, G | 1 |
| Dyer, C | 1 |
| Yang, CS | 1 |
| Kim, C | 1 |
| Antaya, RJ | 1 |
| Sales Luiz Vianna, F | 1 |
| de Oliveira, MZ | 1 |
| Sanseverino, MT | 4 |
| Morelo, EF | 1 |
| de Lyra Rabello Neto, D | 1 |
| Lopez-Camelo, J | 1 |
| Camey, SA | 1 |
| Shiga, T | 1 |
| Shimbo, T | 1 |
| Vianna, FS | 3 |
| Watts, G | 1 |
| Coombes, R | 1 |
| Kazuki, Y | 1 |
| Akita, M | 1 |
| Kobayashi, K | 1 |
| Osaki, M | 1 |
| Satoh, D | 1 |
| Ohta, R | 1 |
| Abe, S | 1 |
| Takehara, S | 1 |
| Kazuki, K | 1 |
| Yamazaki, H | 1 |
| Kamataki, T | 1 |
| Oshimura, M | 1 |
| Beedie, SL | 1 |
| Rore, HM | 1 |
| Barnett, S | 1 |
| Chau, CH | 1 |
| Luo, W | 1 |
| Greig, NH | 1 |
| Figg, WD | 1 |
| Cassina, M | 1 |
| Cagnoli, GA | 1 |
| Zuccarello, D | 1 |
| Di Gianantonio, E | 1 |
| Clementi, M | 1 |
| Tagliani-Ribeiro, A | 1 |
| Godoy, BA | 1 |
| Hutz, MH | 1 |
| Sorensen, D | 1 |
| Sackett, A | 1 |
| Urban, DJ | 1 |
| Maier, J | 1 |
| Sears, KE | 1 |
| Castaneda, CP | 1 |
| Zeldis, JB | 1 |
| Freeman, J | 2 |
| Quigley, C | 1 |
| Brandenburg, NA | 1 |
| Bwire, R | 2 |
| Ekfeldt, A | 1 |
| Carlsson, GE | 1 |
| Jara, M | 1 |
| Khakoo, AY | 1 |
| Sidman, RL | 1 |
| Pasqualini, R | 1 |
| Arap, W | 1 |
| Miller, MT | 9 |
| Strömland, K | 8 |
| Ventura, L | 3 |
| Stephens, TD | 2 |
| Ema, M | 1 |
| Ise, R | 1 |
| Kato, H | 1 |
| Oneda, S | 1 |
| Hirose, A | 1 |
| Hirata-Koizumi, M | 1 |
| Singh, AV | 1 |
| Knudsen, TB | 1 |
| Ihara, T | 1 |
| Reichard-Brown, JL | 1 |
| Spinner, H | 1 |
| McBride, K | 1 |
| Monneret, C | 1 |
| Lefrère, JJ | 1 |
| Berche, P | 1 |
| Wilson, SS | 1 |
| Theodorescu, D | 1 |
| Prommer, EE | 1 |
| Twycross, R | 1 |
| Mihalyo, M | 1 |
| Wilcock, A | 1 |
| Houn, F | 1 |
| Lancaster, PA | 1 |
| Ito, T | 3 |
| Ando, H | 1 |
| Handa, H | 2 |
| Lee, CJ | 2 |
| Gonçalves, LL | 1 |
| Wells, PG | 3 |
| Shibata, N | 1 |
| Wiley, MJ | 1 |
| Kim, JH | 1 |
| Scialli, AR | 1 |
| Lopez-Camelo, JS | 2 |
| Leite, JC | 1 |
| Dutra, Mda G | 1 |
| Castilla, EE | 3 |
| Strömland, KK | 1 |
| Avorn, J | 1 |
| Martínez-Frías, ML | 1 |
| Dursun, A | 1 |
| Karadağ, N | 1 |
| Karagöl, B | 1 |
| Kundak, AA | 1 |
| Zenciroğlu, A | 1 |
| Okumuş, N | 1 |
| Ceylaner, S | 1 |
| Sjögreen, L | 1 |
| Kiliaridis, S | 1 |
| Lachmann, PJ | 1 |
| Emanuel, M | 1 |
| Rawlins, M | 1 |
| Duff, G | 1 |
| Breckenridge, A | 1 |
| Gulland, A | 1 |
| Papaseit, E | 1 |
| García-Algar, O | 1 |
| Farré, M | 1 |
| Sípek, A | 2 |
| Maňáková, E | 1 |
| Philipson, E | 1 |
| Andersson Grönlund, M | 1 |
| Young, D | 1 |
| Ashby, J | 3 |
| Tinwell, H | 3 |
| Cavenagh, JD | 1 |
| Oakervee, H | 1 |
| Daemmrich, A | 1 |
| Matthews, SJ | 1 |
| McCoy, C | 1 |
| Dodd-Butera, T | 1 |
| Broderick, M | 1 |
| Tytherleigh-Strong, G | 1 |
| Hooper, G | 1 |
| BENDA, CE | 1 |
| BAUGHMAN, FA | 1 |
| SURUGA, K | 5 |
| ROBSON, JM | 2 |
| RIEMSCHNEIDER, R | 1 |
| BROCKMEYER, K | 1 |
| IMDAHL, H | 1 |
| HERMANNS, A | 1 |
| KOCH, W | 1 |
| VOTAVA, Z | 2 |
| SOYKOVA PACHNEROVA, E | 1 |
| YANG, TZ | 1 |
| YU, KY | 1 |
| MCBRIDE, WG | 8 |
| DEBOCK, CA | 1 |
| PETERS, A | 1 |
| COHLAN, SQ | 3 |
| WEBB, JF | 1 |
| LARSEN, A | 1 |
| HOLE, LW | 1 |
| MACKENZIE, B | 1 |
| MONIE, IW | 1 |
| WEIDMAN, WH | 1 |
| YOUNG, HH | 1 |
| ZOLLMAN, PE | 1 |
| KELSEY, FO | 5 |
| ANDRIEU, R | 1 |
| STAPLES, RE | 2 |
| HOLTKAMP, DE | 1 |
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| Jonsson, BG | 4 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacologic T Cell Costimulation In HIV Disease[NCT00053430] | Phase 2 | 40 participants (Actual) | Interventional | 2001-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
109 reviews available for thalidomide and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
[Thalidomide embryopathy 60 years].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Female; Fetal Diseases; Humans; Teratog | 2022 |
[Thalidomide embryopathy 60 years].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Female; Fetal Diseases; Humans; Teratog | 2022 |
[Thalidomide embryopathy 60 years].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Female; Fetal Diseases; Humans; Teratog | 2022 |
[Thalidomide embryopathy 60 years].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Female; Fetal Diseases; Humans; Teratog | 2022 |
The organization, weaknesses, and challenges of the control of thalidomide in Brazil: A review.
Topics: Abnormalities, Drug-Induced; Brazil; Erythema Nodosum; Female; Humans; Leprostatic Agents; Leprosy; | 2020 |
The Molecular Mechanisms of Thalidomide Teratogenicity and Implications for Modern Medicine.
Topics: Abnormalities, Drug-Induced; Animals; Biomarkers; Female; Gene Expression Regulation; Humans; Limb D | 2017 |
The teratogenic effects of thalidomide on limbs.
Topics: Abnormalities, Drug-Induced; Extremities; Female; History, 20th Century; History, 21st Century; Huma | 2019 |
Thalidomide and neurotrophism.
Topics: Abnormalities, Drug-Induced; Extremities; Humans; Infant, Newborn; Limb Deformities, Congenital; Per | 2019 |
[Current therapeutic indications of thalidomide and lenalidomide].
Topics: Abnormalities, Drug-Induced; Anti-Inflammatory Agents; Antineoplastic Agents; Collagen Diseases; End | 2014 |
Review of thalidomide use in the pediatric population.
Topics: Abnormalities, Drug-Induced; Adolescent; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Au | 2015 |
Thalidomide-induced teratogenesis: history and mechanisms.
Topics: Abnormalities, Drug-Induced; Adult; Animals; Female; History, 20th Century; History, 21st Century; H | 2015 |
Does the renin-angiotensin system participate in regulation of human vasculogenesis and angiogenesis?
Topics: Abnormalities, Drug-Induced; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood | 2008 |
Congenital aberrant tearing: a re-look.
Topics: Abnormalities, Drug-Induced; Duane Retraction Syndrome; Eye Abnormalities; Female; Humans; Lacrimal | 2008 |
Thalidomide and misoprostol: Ophthalmologic manifestations and associations both expected and unexpected.
Topics: Abnormalities, Drug-Induced; Adult; Autistic Disorder; Child; Child, Preschool; Cranial Nerves; Embr | 2009 |
Rare bladder tumors: caveat emptor.
Topics: Abnormalities, Drug-Induced; Disease Progression; Female; Humans; Lenalidomide; Male; Multiple Myelo | 2010 |
Thalidomide.
Topics: Abnormalities, Drug-Induced; Cardiovascular Diseases; Chronic Disease; Dose-Response Relationship, D | 2011 |
Managing the teratogenic risk of thalidomide and lenalidomide: an industry perspective.
Topics: Abnormalities, Drug-Induced; Contraception; Contraindications; Drug Industry; Female; Humans; Lenali | 2011 |
Causes of birth defects: lessons from history.
Topics: Abnormalities, Drug-Induced; Animals; Australia; Congenital Abnormalities; Female; Fever; History, 2 | 2011 |
Teratogenic effects of thalidomide: molecular mechanisms.
Topics: Abnormalities, Drug-Induced; Adaptor Proteins, Signal Transducing; Animals; Chick Embryo; Fibroblast | 2011 |
[Molecular mechanism of thalidomide teratogenicity].
Topics: Abnormalities, Drug-Induced; Adaptor Proteins, Signal Transducing; Animals; DNA-Binding Proteins; Hu | 2011 |
What can we learn from the thalidomide experience: an ophthalmologic perspective.
Topics: Abnormalities, Drug-Induced; Duane Retraction Syndrome; Eye Abnormalities; Female; Humans; Limb Defo | 2011 |
[The thalidomide experience: review of its effects 50 years later].
Topics: Abnormalities, Drug-Induced; Angiogenesis Inhibitors; Ectromelia; Embryonic Development; Female; His | 2012 |
Thalidomide: a review of approved and investigational uses.
Topics: Abnormalities, Drug-Induced; Anti-HIV Agents; Antineoplastic Agents; Clinical Trials as Topic; Derma | 2003 |
THE PROBLEM OF TERATOGENICITY.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Cyclizine; Female; Imipramine; Nicotine; Preg | 1963 |
[EFFECT OF THALIDOMIDE ON THE PATHOGENESIS OF ABNORMALITIES IN NEWBORN INFANTS].
Topics: Abnormalities, Drug-Induced; Ectromelia; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; P | 1963 |
TERATOGENIC AGENTS AND CONGENITAL MALFORMATIONS.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Aminopterin; Congenital Abnormalities; Female; | 1963 |
[THALIDOMIDE ABNORMALITIES AND THEIR TREATMENT].
Topics: Abnormalities, Drug-Induced; Ectromelia; Surgical Procedures, Operative; Thalidomide; Toxicology | 1963 |
PHARMACOGENETICS.
Topics: Abnormalities, Drug-Induced; Animals; Dicumarol; Dogs; Drug Hypersensitivity; Drug Tolerance; Ethnol | 1964 |
[THALIDOMIDE EMBRYOPATHY. SURVEY AND PATHOGENIC MECHANISM].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Data Collection; Ectromelia; Embryology; Fetal | 1963 |
[ABNORMALLY SHORTENED EXTREMITIES 1950-1962. RESULTS OF A SURVEY].
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Ear Deformities, Acquired; Ear, External; Ect | 1964 |
[PHARMACOGENETICS].
Topics: Abnormalities, Drug-Induced; Atropine; Cleft Palate; Cortisone; Genetics; Glucosephosphate Dehydroge | 1964 |
FETAL AND NEONATAL HAZARDS FROM DRUGS ADMINISTERED DURING PREGNANCY.
Topics: Abnormalities, Drug-Induced; Anti-Bacterial Agents; Anticoagulants; Antimetabolites; Antineoplastic | 1964 |
[CONGENITAL ABNORMALITIES CAUSED BY CHEMICAL AGENTS AND DEFICIENCIES. I].
Topics: Abnormalities, Drug-Induced; Alkaloids; Amino Acids; Anti-Bacterial Agents; Antibodies; Congenital A | 1964 |
[EXOGENOUS MALFORMATIONS].
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Alcohols; Androgens; Anesthetics; Congenital A | 1964 |
[CLINICAL OBSERVATIONS ON PHARMACOGENIC TERATOGENESIS].
Topics: Abnormalities, Drug-Induced; Androgens; Infant, Newborn; Pregnancy; Progestins; Quinine; Teratogenes | 1964 |
[CLINICAL-STATISTICAL STUDIES ON CURRENT MALFORMATION PROBLEM. A REVIEW].
Topics: Abnormalities, Drug-Induced; Biomedical Research; Epidemiology; Germany; Germany, West; Pregnancy; S | 1964 |
CONGENITAL MALFORMATIONS. CLINICAL AND COMMUNITY CONSIDERATIONS.
Topics: Abnormalities, Drug-Induced; Abnormalities, Severe Teratoid; Achondroplasia; Anencephaly; Cleft Pala | 1965 |
[Management of a patient receiving thalidomide].
Topics: Abnormalities, Drug-Induced; Adult; Female; France; Humans; Immunosuppressive Agents; Male; Monitori | 2003 |
Cutaneous sarcoidosis therapy updated.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Allopurinol; Animals; Anti-Inflammatory Agents | 2007 |
Oxidative stress as a mechanism of teratogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Cell Compartmentation; Cell Cycle; Female; Humans; Models, Bio | 2006 |
Thalidomide therapy for inflammatory dermatoses.
Topics: Abnormalities, Drug-Induced; Adult; Animals; Chemical Phenomena; Chemistry; Female; Humans; Immunity | 1984 |
Fetal drug exposure-behavioral teratogenesis.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Behavior; Cannabinoids; Child; Chil | 1984 |
Drugs and pregnancy.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Alcoholic Beverages; Animals; Anticonvulsants; | 1980 |
Review of the treatment of thalidomide children with limb defeciency in Great Britain.
Topics: Abnormalities, Drug-Induced; Acromion; Arm; Child; Ectromelia; Foot Deformities, Congenital; Humans; | 1980 |
Critical periods of prenatal toxic insults.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Embryo, Mammalian; Female; Fetus; Gestational | 1980 |
Forms and causes of human malformations.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Estrogens; Fanconi Anemia; Female; Genes, Dom | 1980 |
In vivo assessment of the teratogenic potential of drugs in humans.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Animals; Cannabis; Diethylstilbestrol; Disease Model | 1981 |
Thalidomide revisited.
Topics: Abnormalities, Drug-Induced; Acquired Immunodeficiency Syndrome; Animals; Behcet Syndrome; Bone Marr | 1994 |
Mechanism of teratogenic action of thalidomide.
Topics: Abnormalities, Drug-Induced; Animals; Ascorbic Acid; Extremities; Female; Humans; Immune System Dise | 1996 |
Never-ending tales of the mode of the teratogenic action of thalidomide.
Topics: Abnormalities, Drug-Induced; Animals; DNA Adducts; DNA Damage; Embryo, Mammalian; Female; Humans; Pr | 1997 |
Oxidative damage in chemical teratogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Antioxidants; Benzo(a)pyrene; Biotransformati | 1997 |
Thalidomide in dermatology. New indications for an old drug.
Topics: Abnormalities, Drug-Induced; Erythema Nodosum; History, 20th Century; Humans; Immunosuppressive Agen | 1997 |
Drugs in pregnancy.
Topics: Abnormalities, Drug-Induced; Animals; Counseling; Dicyclomine; Doxylamine; Drug Combinations; Drug E | 1998 |
Susceptibility in utero and upon neonatal exposure.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Blastocyst; Diethylstilbestrol; Dose-Response | 1998 |
The possibility of epigenetic transmission of defects induced by teratogens.
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Humans; Limb Deformities, Congenita | 1998 |
A looking glass perspective: thalidomide and cyclopamine.
Topics: Abnormalities, Drug-Induced; Animals; Bioethics; Hedgehog Proteins; Humans; Hypnotics and Sedatives; | 1999 |
Thalidomide as an emerging immunotherapeutic agent.
Topics: Abnormalities, Drug-Induced; Acquired Immunodeficiency Syndrome; Adjuvants, Immunologic; Anti-Inflam | 1999 |
Hypothesis: thalidomide embryopathy-proposed mechanism of action.
Topics: Abnormalities, Drug-Induced; Animals; Embryonic and Fetal Development; Female; Gene Expression Regul | 2000 |
[Fetal thalidomide syndrome].
Topics: Abnormalities, Drug-Induced; Female; Fetal Diseases; Humans; Hypnotics and Sedatives; Infant, Newbor | 2001 |
[The thalidomide story and its lessons].
Topics: Abnormalities, Drug-Induced; Anti-HIV Agents; Antineoplastic Agents; Female; Germany; History, 20th | 2001 |
[New indications for thalidomide?].
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Angiogenesis Inhibitors; Animals; Anti-HIV Agents; A | 2001 |
[Thalidomide--a dreaded drug with new indications].
Topics: Abnormalities, Drug-Induced; Anti-HIV Agents; Contraindications; Dermatologic Agents; Female; Histor | 2001 |
Molecular basis of environmentally induced birth defects.
Topics: Abnormalities, Drug-Induced; Animals; Embryonic and Fetal Development; Female; Gene Expression Regul | 2002 |
Thalidomide in Behçet's disease.
Topics: Abnormalities, Drug-Induced; Adult; Age Factors; Behcet Syndrome; Child; Humans; Immunosuppressive A | 2002 |
Mechanisms of limb development and malformation.
Topics: Abnormalities, Drug-Induced; Animals; Cell Differentiation; Chick Embryo; Extremities; Genetics; Lim | 1976 |
Syndromes with reduction and surplus anomalies of the hand.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Fanconi Syndrome; Female; Fingers; Hand Deform | 1977 |
[On certain embryopathies induced by teratogenic agents (author's transl].
Topics: Abnormalities, Drug-Induced; Aminopterin; Busulfan; Chlorambucil; Cyclophosphamide; Ethanol; Germany | 1977 |
Thalidomide embryopathy.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Bone and Bones; Disease Models, Anima | 1977 |
Pathogenesis of congenital malformations. An hypothesis.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Congenital Abnormalities; Female; Ganglia, Spi | 1978 |
[Transplacental carcinogenesis].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abnormalities, Drug-Induced; Adenocarcinoma; Animals; Carcinogens; | 1977 |
[Theoretical and applied aspects of experimental teratology].
Topics: Abnormalities, Drug-Induced; Aminopterin; Animals; Dactinomycin; DNA Replication; Dose-Response Rela | 1977 |
Drug-induced somatic alterations.
Topics: Abnormalities, Drug-Induced; Alcoholism; Animals; Anticonvulsants; Cannabis; Environmental Exposure; | 1975 |
Embryological pigment epithelial dystrophies.
Topics: Abnormalities, Drug-Induced; Anti-Bacterial Agents; Deafness; Female; Fluorescein Angiography; Human | 1976 |
Thalidomide embryopathy: a model for the study of congenital incomitant horizontal strabismus.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Duane Retraction Syndrome; Embryo, Mamm | 1991 |
[Current use of thalidomide].
Topics: Abnormalities, Drug-Induced; Behcet Syndrome; Dose-Response Relationship, Drug; Humans; Leprosy, Lep | 1990 |
Drug therapy in pregnancy: the lessons of diethylstilbestrol, thalidomide, and bendectin.
Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Diethylstilbestrol; Doxylamine; Drug Combinat | 1990 |
Research and practice with congenital amputees: making the whole greater than the sum of its parts.
Topics: Abnormalities, Drug-Induced; Artificial Limbs; Child; Combined Modality Therapy; Ectromelia; Humans; | 1990 |
A short history of thalidomide embryopathy.
Topics: Abnormalities, Drug-Induced; Female; Humans; Male; Pregnancy; Radiography; Teratogens; Thalidomide | 1988 |
[Human genetic aspects of inborn ear, nose, and throat diseases].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Acrocephalosyndactylia; Child, Preschool; Chro | 1985 |
Monitoring for congenital malformations.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Birth Certificates; England; Environmental Healt | 1986 |
Testing drugs for teratogenicity and their effects on fertility. The present position.
Topics: Abnormalities, Drug-Induced; Animals; Cannabis; Chlormadinone Acetate; Female; Fertility; Fetal Deat | 1970 |
Dermatoglyphics.
Topics: Abnormalities, Drug-Induced; Anemia, Sickle Cell; Anencephaly; Cerebral Palsy; Chromosome Aberration | 1968 |
[Diseases and dermatoglyphics].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Bone and Bones; Chromosome Aberrations; Chromo | 1970 |
Phenocopies.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anemia, Aplastic; Anorexia Nervosa; Arm; Cleft | 1973 |
[Several problems of drug therapy in pregnancy].
Topics: Abnormalities, Drug-Induced; Anti-Bacterial Agents; Antineoplastic Agents; Antitubercular Agents; Ca | 1971 |
Thalidomide revisited.
Topics: Abnormalities, Drug-Induced; Animals; Dogs; Female; Fetus; Humans; Pregnancy; Rats; Thalidomide | 1972 |
[Drugs and congenital anomalies of the central nervous system].
Topics: Abnormalities, Drug-Induced; Animals; Brain; Carbon Monoxide Poisoning; Central Nervous System; Drug | 1972 |
[Teratogenic and mutagenic effects of anticonvulsive and psychotropic drugs (review of the literature)].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Antidepressive Agent | 1972 |
[Nutritional background and sensitivity of the organism to toxic substances].
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Diet; Dietary Carbohydrates; Dietary | 1972 |
The Mondini type of cochlear malformation. A survey of the literature.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Adult; Aged; Animals; Child, Presc | 1972 |
Chemical structure and teratogenic properties. 3. A review of available data on structure-activity relationships and mechanism of action of thalidomide analogues.
Topics: Abnormalities, Drug-Induced; Animals; Drug Interactions; Folic Acid; Glutamates; Humans; Hydrolysis; | 1972 |
Present status of drugs as teratogens in man.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Anti-Bacterial Agents; Anticonvulsants; Antiemetics; | 1973 |
Congenital malformations and environmental influence: the occupational environment of laboratory workers.
Topics: Abnormalities, Drug-Induced; Anesthetics; Anti-Bacterial Agents; Benzene; California; Congenital Abn | 1973 |
Toxicology and the environment.
Topics: Abnormalities, Drug-Induced; Animals; Breast Neoplasms; Carcinogens; Contraceptives, Oral; Culture T | 1973 |
Drugs in pregnancy and their effects on pre- and postnatal development.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Animals; Anticonvulsants; Antimetabolites; Central N | 1973 |
The fetal and neonatal pig in biomedical research.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anemia, Hypochromic; Animals; Animals, Laborat | 1974 |
Principles of teratology.
Topics: Abnormalities, Drug-Induced; Amniocentesis; Animals; Chromosome Aberrations; Chromosome Disorders; C | 1972 |
Human organ culture: applications in the screening of teratogenic drugs.
Topics: Abnormalities, Drug-Induced; Amino Acids; Anti-Bacterial Agents; Atmosphere; Carbon Dioxide; Culture | 1974 |
[The fawn rabbit of Burgundy in teratology. Spontaneous malformations and malformations provoked by thalidomide].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Rabbits; Teratogens; Thalidomide | 1974 |
Abnormalities of intrauterine development in non-human primates.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Abortion, Spontaneous; Animals; Antineoplastic | 1972 |
Certain causes of congenital malformations in Homo sapiens and their prevention.
Topics: Abnormalities, Drug-Induced; Abortion, Therapeutic; Aminopterin; Antigen-Antibody Reactions; Chromos | 1967 |
The pathogenesis of congenital cardiovascular anomalies.
Topics: Abnormalities, Drug-Induced; Animals; Azo Compounds; Embryology; Female; Heart; Heart Defects, Conge | 1968 |
[Teratogenic molecules].
Topics: Abnormalities, Drug-Induced; Animals; Drug-Related Side Effects and Adverse Reactions; Female; Human | 1967 |
Etiology of congenital heart disease.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Chromosome Aberrations; Chromosome Disorders; | 1969 |
[Effect of drugs, ingested by the mother during pregnancy, on the fetus].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Caffeine; Female; Humans; Meclizine; Pregnancy; | 1969 |
[Some current problems of experimental teratology].
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Female; Hypoxia; Methods; Mice; Pregnancy; Rabbi | 1967 |
[Fetal diseases caused by environmental polltuion].
Topics: Abnormalities, Drug-Induced; Air Pollution; Congenital Abnormalities; Environment; Environmental Pol | 1971 |
[Studies in experiment animals and dysmelia syndrome].
Topics: Abnormalities, Drug-Induced; Animals; Anura; Cats; Chickens; Cricetinae; Dogs; Drosophila; Guinea Pi | 1966 |
[Combined abnormalities of the ear and eye].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Craniofacial Dysostosis; Ear; Embryology; Eye | 1967 |
Malformations caused by drugs in pregnancy.
Topics: Abnormalities, Drug-Induced; Aminopterin; Animals; Cyclophosphamide; Female; Humans; Infant, Newborn | 1966 |
Experimental and clinical chemoteratogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents; Female; Hormones; Humans; In Vitro Tech | 1966 |
The mechanism of thalidomide deformities correlated with the pathogenic effects of prolonged dosage in adults.
Topics: Abnormalities, Drug-Induced; Adult; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregna | 1966 |
1 trial available for thalidomide and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Thalidomide in America: a brush with tragedy.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Clinical Trials as Topic; Drug Evaluation; Fem | 1976 |
664 other studies available for thalidomide and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Commentary on Markiewicz et al. Age-related changes in patients with upper limb thalidomide embryopathy in the United Kingdom.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Female; Fetal Diseases; Humans; Thalidomide; U | 2023 |
Quality of life and pain in patients with thalidomide embryopathy in Japan.
Topics: Abnormalities, Drug-Induced; Adaptation, Psychological; Adult; Aged; Female; Humans; Japan; Male; Ma | 2020 |
"The legacy of thalidomide" - A multidisciplinary meeting held at the University of York, United Kingdom, on September 30, 2016.
Topics: Abnormalities, Drug-Induced; Adult; Aging; Child; Disabled Persons; Female; Humans; Hypnotics and Se | 2017 |
Middle-aged individuals with thalidomide embryopathy have undergone few surgical limb procedures and demonstrate a high degree of physical independence.
Topics: Abnormalities, Drug-Induced; Activities of Daily Living; Adult; Congenital Abnormalities; Female; Hu | 2017 |
Genetic susceptibility to thalidomide embryopathy in humans: Study of candidate development genes.
Topics: Abnormalities, Drug-Induced; Female; Genetic Predisposition to Disease; Genotype; Humans; Infant, Ne | 2018 |
Life situation of women impaired by Thalidomide embryopathy in North Rhine-Westphalia - a comparative analysis of a recent cross-sectional study with earlier data.
Topics: Abnormalities, Drug-Induced; Adult; Cross-Sectional Studies; Female; Fetal Diseases; Germany; Humans | 2019 |
[Independence of former Contergan children compromised].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Female; Humans; Hypnotics and Sedatives; Pregn | 2013 |
Thromboembolism and congenital malformations: from Duane syndrome to thalidomide embryopathy.
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Duane Retraction Syndrome; Eye Abnormalities; Female; F | 2013 |
No, not more talk about Duane syndrome.
Topics: Abnormalities, Drug-Induced; Duane Retraction Syndrome; Eye Abnormalities; Female; Fetal Diseases; H | 2013 |
Peripheral arterial reconstruction in a patient with thalidomide embryopathy and chronic occlusion of the femoral artery.
Topics: Abnormalities, Drug-Induced; Antiemetics; Arterial Occlusive Diseases; Chronic Disease; Constriction | 2013 |
Concern for truth: driving defensively when confronting a zombie epidemic.
Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Histor | 2013 |
Common nature in the effects of thalidomide on embryo-fetal development in Kbl:JW and Kbl:NZW rabbits.
Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic | 2014 |
Effects of thalidomide on Fgf8, Bmp4 and Hoxa11 expression in the limb bud in Kbl:JW rabbit embryos.
Topics: Abnormalities, Drug-Induced; Animals; Bone Morphogenetic Protein 4; Embryo, Mammalian; Embryonic Dev | 2014 |
Psychological and mental health problems in patients with thalidomide embryopathy in Japan.
Topics: Abnormalities, Drug-Induced; Cognition; Electroencephalography; Female; Health Status; Humans; Intel | 2014 |
Cases of babies in Brazil born with thalidomide defects.
Topics: Abnormalities, Drug-Induced; Brazil; Drug Repositioning; Ethics, Pharmacy; Female; Humans; Infant; M | 2013 |
50 years ago in the Journal of pediatrics: Drug testing in animals for teratogenic effects. Thalidomide in the pregnant rat.
Topics: Abnormalities, Drug-Induced; Animals; Female; History, 20th Century; Models, Animal; Pediatrics; Per | 2014 |
Embryo-fetal exposure and developmental outcome of thalidomide following oral and intravaginal administration to pregnant rabbits.
Topics: Abnormalities, Drug-Induced; Administration, Intravaginal; Administration, Oral; Animals; Embryo, Ma | 2014 |
Eight more people in UK sue Grünenthal and Diageo over thalidomide.
Topics: Abnormalities, Drug-Induced; Compensation and Redress; Drug Industry; Humans; Teratogens; Thalidomid | 2014 |
Pharmacoepidemiology and thalidomide embryopathy surveillance in Brazil.
Topics: Abnormalities, Drug-Induced; Brazil; Drug Prescriptions; Female; Humans; Infant, Newborn; Leprosy; P | 2015 |
Multicenter investigation of lifestyle-related diseases and visceral disorders in thalidomide embryopathy at around 50 years of age.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Cross-Sectional Studies; Female; Fetal Disease | 2015 |
Thalidomide embryopathy: Follow-up of cases born between 1959 and 2010.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Adult; Brazil; Child, Preschool; F | 2015 |
Frances Oldham Kelsey.
Topics: Abnormalities, Drug-Induced; Canada; Drug Approval; History, 20th Century; Teratogens; Thalidomide; | 2015 |
Attacking the devil: the thalidomide story.
Topics: Abnormalities, Drug-Induced; Antiemetics; Child; Europe; Female; History, 20th Century; Humans; Male | 2016 |
Thalidomide-induced limb abnormalities in a humanized CYP3A mouse model.
Topics: Abnormalities, Drug-Induced; Animals; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Embryo | 2016 |
In vivo screening and discovery of novel candidate thalidomide analogs in the zebrafish embryo and chicken embryo model systems.
Topics: Abnormalities, Drug-Induced; Angiogenesis Inhibitors; Animals; Animals, Genetically Modified; Anti-I | 2016 |
Human teratogens and genetic phenocopies. Understanding pathogenesis through human genes mutation.
Topics: Abnormalities, Drug-Induced; Angiotensin-Converting Enzyme Inhibitors; Animals; Female; Fetal Diseas | 2017 |
Genomic and in silico analyses of CRBN gene and thalidomide embryopathy in humans.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adaptor Proteins, Signal Transducing; Binding | 2016 |
A new mammalian model system for thalidomide teratogenesis: Monodelphis domestica.
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Embryonic Development; Female; Models, Anim | 2017 |
RevAssist: a comprehensive risk minimization programme for preventing fetal exposure to lenalidomide.
Topics: Abnormalities, Drug-Induced; Antineoplastic Agents; Female; Fetus; Humans; Lenalidomide; Male; Mater | 2008 |
Dental status and oral function in an adult group of subjects with thalidomide embryopathy - a clinical and questionnaire study.
Topics: Abnormalities, Drug-Induced; Anodontia; Dental Care for Disabled; Dental Caries; DMF Index; Female; | 2008 |
Campaigners demand equal treatment for all thalidomide victims.
Topics: Abnormalities, Drug-Induced; Compensation and Redress; Humans; Teratogens; Thalidomide | 2008 |
The effect of thalidomide in chicken embryos.
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Dose-Response Relationship, Drug; Extremities; L | 2009 |
Fetal malformations and early embryonic gene expression response in cynomolgus monkeys maternally exposed to thalidomide.
Topics: Abnormalities, Drug-Induced; Animals; Female; Gene Expression; Gene Expression Profiling; Gestationa | 2010 |
History, heresy and radiology in scientific discovery.
Topics: Abnormalities, Drug-Induced; History, 20th Century; History, 21st Century; Humans; Radiography; Radi | 2009 |
Sea urchin embryos exposed to thalidomide during early cleavage exhibit abnormal morphogenesis later in development.
Topics: Abnormalities, Drug-Induced; Animal Testing Alternatives; Animals; Embryo, Nonmammalian; Embryonic D | 2009 |
[Reinventing thalidomide under high supervision].
Topics: Abnormalities, Drug-Induced; Adult; Aged; Antineoplastic Agents; Device Approval; Female; History, 2 | 2010 |
Les bébés du thalidomide.
Topics: Abnormalities, Drug-Induced; Drug Industry; Ectromelia; Female; France; History, 20th Century; Human | 2011 |
Resistance of CD-1 and ogg1 DNA repair-deficient mice to thalidomide and hydrolysis product embryopathies in embryo culture.
Topics: Abnormalities, Drug-Induced; Animals; DNA Damage; DNA Glycosylases; DNA Repair; DNA Repair-Deficienc | 2011 |
Fluorothalidomide: a characterization of maternal and developmental toxicity in rabbits and mice.
Topics: Abnormalities, Drug-Induced; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationsh | 2011 |
Thalidomide: the tragedy of birth defects and the effective treatment of disease.
Topics: Abnormalities, Drug-Induced; Angiogenesis Inhibitors; Animals; Dose-Response Relationship, Drug; Ect | 2011 |
Epidemiological surveillance of birth defects compatible with thalidomide embryopathy in Brazil.
Topics: Abnormalities, Drug-Induced; Adult; Brazil; Female; Fetal Diseases; Geography; Humans; Infant, Newbo | 2011 |
Learning about the safety of drugs--a half-century of evolution.
Topics: Abnormalities, Drug-Induced; Drug-Related Side Effects and Adverse Reactions; Government Regulation; | 2011 |
Carbamazepine use in pregnancy and coincidental thalidomide-like phocomelia in a newborn.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Ectromelia; Female; Humans; Infant, New | 2012 |
Facial palsy in individuals with thalidomide embryopathy: frequency and characteristics.
Topics: Abnormalities, Drug-Induced; Adult; Case-Control Studies; Facial Expression; Facial Paralysis; Femal | 2012 |
The penumbra of thalidomide, the litigation culture and the licensing of pharmaceuticals.
Topics: Abnormalities, Drug-Induced; Animals; Child; Drug Costs; Female; Humans; Jurisprudence; Licensure; M | 2012 |
Thalidomide and its sequelae.
Topics: Abnormalities, Drug-Induced; Antiemetics; Drug and Narcotic Control; History, 20th Century; Humans; | 2012 |
Thalidomide manufacturer offers apology but no compensation.
Topics: Abnormalities, Drug-Induced; Compensation and Redress; Drug Industry; Humans; Thalidomide | 2012 |
[Thalidomide: an unfinished history].
Topics: Abnormalities, Drug-Induced; History, 20th Century; Humans; Infant, Newborn; Teratogens; Thalidomide | 2013 |
[Thalidomide epidemics: 50 years after].
Topics: Abnormalities, Drug-Induced; Female; History, 20th Century; Humans; Infant; Limb Deformities, Congen | 2012 |
Offspring of male and female parents with thalidomide embryopathy: birth defects and functional anomalies.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Child; Child, Preschool; Congenital Abnormalities; F | 2002 |
Thalidomide prescribers cannot assign survey responsibility to pharmacists.
Topics: Abnormalities, Drug-Induced; Antineoplastic Agents; Data Collection; Drug Prescriptions; Female; Hum | 2002 |
Thalidomide is not a human mutagen.
Topics: Abnormalities, Drug-Induced; Child; Female; Humans; Male; Mutagens; Thalidomide | 2002 |
Thalidomide in multiple myeloma: current status and future prospects.
Topics: Abnormalities, Drug-Induced; Adjuvants, Immunologic; Angiogenesis Inhibitors; Antineoplastic Combine | 2003 |
A tale of two experts: thalidomide and political engagement in the United States and West Germany.
Topics: Abnormalities, Drug-Induced; Germany; Government Regulation; History, 20th Century; Humans; Infant; | 2002 |
Thalidomide makes a comeback.
Topics: Abnormalities, Drug-Induced; Angiogenesis Inhibitors; Ectromelia; Erythema Nodosum; Female; Humans; | 2003 |
The classification of phocomelia.
Topics: Abnormalities, Drug-Induced; Ectromelia; Humans; Radiography; Thalidomide | 2003 |
[AN UNUSUAL CASE OF DEVELOPMENTAL DISORDER--PROBABLY BASED ON PRENATAL THALIDOMIDE DAMAGE, WITH CHROMOSOMAL ANALYSIS].
Topics: Abnormalities, Drug-Induced; Child; Chromosome Aberrations; Chromosome Disorders; Developmental Disa | 1963 |
[SURGERY ON THALIDOMIDE ABNORMALITIES].
Topics: Abnormalities, Drug-Induced; Extremities; Infant, Newborn; Surgical Procedures, Operative; Thalidomi | 1963 |
[TERATOGENIC EFFECT OF ORGANIC COMPOUNDS. III. FURTHER THALIDOMIDE EXPERIMENTS].
Topics: Abnormalities, Drug-Induced; Animals; Mammals; Organic Chemicals; Research; Teratogenesis; Thalidomi | 1963 |
[THALIDOMIDE AND RECTO-ANAL ATRESIA].
Topics: Abnormalities, Drug-Induced; Anal Canal; Anus, Imperforate; Biometry; Germany; Germany, West; Infant | 1963 |
[CONTINUOUS RISE IN THE INCIDENCE OF PHOCOMELIA IN NEWBORN INFANTS IN WESTERN EUROPE AND ITS RELATION TO THALIDOMIDE ADMINISTRATION. CURRENT STATUS OF THE PROBLEM].
Topics: Abnormalities, Drug-Induced; Drug Tolerance; Ectromelia; Europe; Female; Germany; Germany, West; Inc | 1963 |
[THE INCIDENCE OF DEFORMITIES OF THE EXTREMITIES IN HAMBURG IN THE YEARS 1960 TO 1962].
Topics: Abnormalities, Drug-Induced; Abnormalities, Severe Teratoid; Ear Deformities, Acquired; Ear, Externa | 1963 |
[1ST CASE REPORT FROM FORMOSA OF A CONGENITAL ANOMALY PROBABLY INDUCED BY THALIDOMIDE].
Topics: Abnormalities, Drug-Induced; Arm; China; Hand; Pregnancy; Taiwan; Thalidomide; Toxicology | 1962 |
THE TERATOGENIC ACTION OF DRUGS.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Australia; Chlorothiazide; Cyclizine; Hydroflumethiazide | 1963 |
EFFECT OF THALIDOMIDE ON THE DEVELOPMENT OF THE CHICK EMBRYO.
Topics: Abnormalities, Drug-Induced; Chick Embryo; Research; Thalidomide; Toxicology | 1963 |
CANADIAN THALIDOMIDE EXPERIENCE.
Topics: Abnormalities, Drug-Induced; Canada; Ectromelia; Extremities; Female; Fetal Death; Humans; Infant; I | 1963 |
[EFFECT OF DRUGS ON THE DEVELOPMENT OF THE FETUS WITH REFERENCE TO THE TERATOGENIC EFFECT OF THALIDOMIDE].
Topics: Abnormalities, Drug-Induced; Animals; Ectromelia; Female; Fetus; Humans; Pharmacology; Pregnancy; Te | 1963 |
CONGENITAL DEFORMITIES ASSOCIATED WITH THE USE OF THALIDOMIDE DURING PREGNANCY, BRITISH COLUMBIA, 1961-62.
Topics: Abnormalities, Drug-Induced; British Columbia; Canada; Ectromelia; Humans; Infant, Newborn; Infant, | 1963 |
INFLUENCE OF THE ENVIRONMENT ON THE UNBORN.
Topics: Abnormalities, Drug-Induced; Aminopterin; Animals; Communicable Diseases; Congenital Abnormalities; | 1963 |
THE EFFECT OF THALIDOMIDE ON THE UNBORN PUPPY.
Topics: Abnormalities, Drug-Induced; Animals; Dogs; Extremities; Female; Humans; Pregnancy; Pregnancy, Anima | 1963 |
DRUG EMBRYOPATHY: THE THALIDOMIDE STORY.
Topics: Abnormalities, Drug-Induced; Anti-Bacterial Agents; Female; Fetal Diseases; Glutethimide; Humans; In | 1963 |
[HOW TO EXPLAIN THE TERATOGENIC ACTION OF THALIDOMIDE].
Topics: Abnormalities, Drug-Induced; Ectromelia; Pregnancy; Teratogenesis; Teratogens; Thalidomide; Toxicolo | 1963 |
EFFECTS OF PARENTAL THALIDOMIDE TREATMENT ON GESTATION AND FETAL DEVELOPMENT.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Development; Humans; Lagomorpha; Maternal-Fetal | 1963 |
[POSSIBILITIES OF AID ACCORDING TO FEDERAL LEGISLATION ON SOCIAL ASSISTANCE FOR SUBJECTS WITH SEVERE ABNORMALITIES WITH SPECIAL REFERENCE TO REHABILITATION FOR THE HANDICAPPED].
Topics: Abnormalities, Drug-Induced; Artificial Limbs; Congenital Abnormalities; Disabled Persons; Germany; | 1963 |
[CONTROL OF AND EXPERIMENTATION WITH DRUGS].
Topics: Abnormalities, Drug-Induced; Empirical Research; Ethics, Medical; France; Legislation, Medical; Phar | 1963 |
[TERATOGENIC ACTION OF DRUGS IN THE PREGNANT WOMAN].
Topics: Abnormalities, Drug-Induced; Antineoplastic Agents; Avitaminosis; Chlorpromazine; Cortisone; Female; | 1963 |
[SURGERY ON THALIDOMIDE ABNORMALITIES].
Topics: Abnormalities, Drug-Induced; Humans; Infant; Surgical Procedures, Operative; Thalidomide; Toxicology | 1963 |
[SURGICAL TREATMENT OF CONGENITAL ANOMALIES IN THE NEONATAL PERIOD].
Topics: Abnormalities, Drug-Induced; Esophageal Stenosis; Humans; Infant, Newborn; Infant, Newborn, Diseases | 1963 |
[THALIDOMIDE-DEFORMED INFANTS].
Topics: Abnormalities, Drug-Induced; Ectromelia; Infant, Newborn; Medicine; Rehabilitation; Thalidomide; Tox | 1963 |
[CASE OF TOTAL AMELIA THOUGHT TO BE DUE TO THALIDOMIDE].
Topics: Abnormalities, Drug-Induced; Ectromelia; Extremities; Infant, Newborn; Pregnancy; Radiography; Thali | 1963 |
THALIDOMIDE INDUCED ALTERATIONS IN THE BLASTOCYST AND PLACENTA OF THE ARMADILLO, DASYPUS NOVEMCINCTUS MEXICANUS, INCLUDING A CHORIOCARCINOMA.
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Abortion, Spontaneous; Abortion, Veterinary; Animals | 1963 |
[1ST CASE OF THALIDOMIDE EMBRYOPATHY STUDIED IN FRANCE].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Ectromelia; Fetal Diseases; France; Infant, Ne | 1963 |
EFFECTS OF THALIDOMIDE IN THE RAT FOETUS.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Female; Fetus; Humans; Maternal-Fetal Exchan | 1963 |
[DRUG CONSUMPTION BY PREGNANT WOMEN AFTER CAUTIONS ON THALIDOMIDE. II. III].
Topics: Abnormalities, Drug-Induced; Alcoholic Beverages; Health Education; Humans; Pharmaceutical Preparati | 1963 |
[CONGENITAL MALFORMATIONS IN JAPAN].
Topics: Abnormalities, Drug-Induced; Classification; Congenital Abnormalities; Infant, Newborn; Japan; Pregn | 1963 |
[THE CONGENITAL ABNORMALITY, PHOCOMELIA, CAUSED BY CHEMICAL SUBSTANCES].
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Ectromelia; Female; Guinea Pigs; Humans; Pha | 1963 |
[TWINS WITH MALFORMATIONS OF THE EXTREMITIES. THALIDOMIDE EMBRYOPATHY. 3].
Topics: Abnormalities, Drug-Induced; Diseases in Twins; Ectromelia; Fetal Diseases; Infant, Newborn; Syndrom | 1963 |
PROBLEMS RAISED FOR THE FDA BY THE OCCURRENCE OF THALIDOMIDE EMBRYOPATHY IN GERMANY 1960-1961.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Fetal Diseases; Geriatrics; Germany; Germany, | 1964 |
TERATOGENIC ACTIVITY OF DRUGS.
Topics: Abnormalities, Drug-Induced; Fetal Death; Guanethidine; Pregnancy; Rats; Research; Reserpine; Thalid | 1964 |
TERATOGENIC ACTION OF THALIDOMIDE.
Topics: Abnormalities, Drug-Induced; Female; Folic Acid; Glutamine; Niacinamide; Pregnancy; Pregnancy Compli | 1964 |
EFFECT OF METHAQUALONE HYDROCHLORIDE IN PREGNANT RABBITS AND RATS.
Topics: Abnormalities, Drug-Induced; Animals; Female; Humans; Hypnotics and Sedatives; Methaqualone; Pregnan | 1963 |
[THALIDOMIDE EMBRYOPATHY IN ITALY].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Fetal Diseases; Italy; Statistics as Topic; Sy | 1963 |
[THALIDOMIDE EMBRYOPATHIES IN MILANO AND SUBURBS. ANATOMO-CLINICAL STUDY].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Biomedical Research; Ectromelia; Fetal Disease | 1963 |
[EXPERIMENTS WITH CONTERGAN IN CHICK EMBRYOS. PRELIMINARY RESULTS].
Topics: Abnormalities, Drug-Induced; Cardiovascular System; Chick Embryo; Ectromelia; Kidney; Liver; Myocard | 1963 |
[TWINS WITH MALFORMATIONS OF THE EXTREMITIES. THALIDOMIDE EMBRYOPATHY. III].
Topics: Abnormalities, Drug-Induced; Diseases in Twins; Ectromelia; Fetal Diseases; Infant, Newborn; Syndrom | 1963 |
[TOXIC AND TERATOGENIC EFFECTS OF THALIDOMIDE ON A RABBIT FETUS].
Topics: Abnormalities, Drug-Induced; Animals, Newborn; Ectromelia; Fetal Diseases; Fetus; Pregnancy; Pregnan | 1963 |
OBSERVATIONS ON PROGENY OF THALIDOMIDE-TREATED MALE RABBITS.
Topics: Abnormalities, Drug-Induced; Animal Experimentation; Animals; Fertilization; Lagomorpha; Male; Rabbi | 1964 |
[COMMENTARIES ABOUT 107 CONGENITAL MALFORMATIONS].
Topics: Abnormalities, Drug-Induced; Aminopterin; Chromosome Aberrations; Chromosome Disorders; Congenital A | 1963 |
[ON THE FORMAL GENESIS OF EAR ABNORMALITIES IN THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Coenzymes; Ear; Fetal Diseases; Humans; Infant | 1963 |
[DRUG USE DURING PREGNANCY AFTER DISCOVERY OF THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Drug-Induced; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Ectromelia; Female; | 1964 |
CONGENITAL MALFORMATIONS ASSOCIATED WITH THALIDOMIDE AND THEIR MANAGEMENT.
Topics: Abnormalities, Drug-Induced; Artificial Limbs; Disease Management; Ectromelia; Humans; Infant, Newbo | 1964 |
[CONGENITAL MALFORMATIONS OF SKELETON IN RABBITS].
Topics: Abnormalities, Drug-Induced; Animals; Bone Diseases; Female; Humans; Lagomorpha; Mucopolysaccharidos | 1964 |
[TERATOGENIC SUBSTANCES?].
Topics: Abnormalities, Drug-Induced; Ectromelia; Fetal Diseases; Infant, Newborn; Meclizine; Phenmetrazine; | 1964 |
DIAGNOSIS AND TREATMENT OF UNWANTED REACTIONS TO DRUGS.
Topics: Abnormalities, Drug-Induced; Drug Hypersensitivity; Humans; Thalidomide; Toxicology | 1964 |
[A NEW THALIDOMIDE CASE].
Topics: Abnormalities, Drug-Induced; Arm; Hand Deformities; Infant, Newborn; Pregnancy; Radiography; Radius; | 1964 |
THE TERATOGENIC EFFECTS OF THALIDOMIDE, IMIPRAMINE HC1 AND IMIPRAMINE-N-OXIDE HC1 ON WHITE DANISH RABBITS.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Female; Fetal Diseases; Humans; Imipramine; | 1963 |
[TERSTOGENIC SUBSTANCES?].
Topics: Abnormalities, Drug-Induced; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Meclizine; Ph | 1963 |
PSYCHIATRIC INDICATIONS FOR THERAPEUTIC ABORTION AND STERILIZATION.
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Abortion, Therapeutic; Depression; Family; Female; H | 1964 |
[EAR DEFORMITIES IN THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Drug-Induced; Cleft Palate; Congenital Abnormalities; Cryptorchidism; Ear Deformities | 1964 |
[THALIDOMIDE SYNDROME AND THE TREATMENT OF THALIDOMIDE CASES].
Topics: Abnormalities, Drug-Induced; Hand Deformities; Infant, Newborn; Pregnancy; Syndrome; Thalidomide; To | 1964 |
[ACTION ON PREGNANCY AND FETAL DEVELOPMENT OF A GLUTARIMIC DERIVATIVE, ATURBANE].
Topics: Abnormalities, Drug-Induced; Animals; Fetal Development; Fetus; Hypnotics and Sedatives; Lagomorpha; | 1964 |
[INVESTIGATION ON THE POSSIBLE RELATION OF FETAL INJURIES AND DRUGS. IV. RETROSPECTIVE STUDY ON DRUG CONSUMPTION AMONG MOTHERS WITH MALFORMED CHILDREN].
Topics: Abnormalities, Drug-Induced; Diphenhydramine; Down Syndrome; Fetal Diseases; Hip Dislocation; Hip Di | 1964 |
THE CHILD WITH CONGENITAL LIMB DEFORMITIES.
Topics: Abnormalities, Drug-Induced; Achondroplasia; Arm; Congenital Abnormalities; Ectromelia; Education; F | 1964 |
EXPERIMENTAL TERATOGENESIS IN RELATION TO CONGENITAL MALFORMATIONS IN MAN.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Bacterial Agents; Caffeine; Cortisone; Insulin; Lagomorph | 1964 |
[THALIDOMIDE ABNORMALITIES].
Topics: Abnormalities, Drug-Induced; Child; Child Care; Child Welfare; Ectromelia; Humans; Infant, Newborn; | 1964 |
REPORT FROM THE DUKE UNIVERSITY POISON CONTROL CENTER. DRUG DANGERS (MATERNAL MEDICATION) TO THE FETUS.
Topics: Abnormalities, Drug-Induced; Aminopterin; Anti-Bacterial Agents; Antimetabolites; Chloramphenicol; C | 1964 |
DRUG TESTING IN ANIMALS FOR TERATOGENIC EFFECTS. THALIDOMIDE IN THE PREGNANT RAT.
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Embryo, Nonmammalian; Female; Humans; Injec | 1964 |
[METABOLISM OF THALIDOMIDE. II. PRELIMINARY STUDIES ON THE MECHANISM OF ACTION OF THALIDOMIDE].
Topics: Abnormalities, Drug-Induced; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carboxy-Lya | 1963 |
[THE PATHOGENESIS OF VARIOUS EXTERNAL MALFORMATIONS AS A CONSEQUENCE OF EXOGENOUS STIMULI IN MAMMALS].
Topics: Abnormalities, Drug-Induced; Animals; Cyclophosphamide; Ectromelia; Female; Humans; Lagomorpha; Mamm | 1963 |
MAMMALIAN BLASTOPATHIOS DUE TO DRUGS.
Topics: Abnormalities, Drug-Induced; Animals; Cyclophosphamide; Female; Humans; Mammals; Mechlorethamine; Pr | 1964 |
CONGENITAL ANOMALIES OF THE LIMBS. I. MEDICAL ASPECTS.
Topics: Abnormalities, Drug-Induced; Artificial Limbs; Child; Classification; Ectromelia; Extremities; Femal | 1964 |
MALFORMATIONS INDUCED IN THE MOUSE BY THALIDOMIDE.
Topics: Abnormalities, Drug-Induced; Animals; Bone Diseases; Embryo, Mammalian; Embryo, Nonmammalian; Female | 1964 |
EAR ABNORMALITIES AND CRANIAL NERVE PALSIES IN THALIDOMIDE CHILDREN.
Topics: Abnormalities, Drug-Induced; Child; Cranial Nerve Diseases; Cranial Nerves; Deafness; Ear Deformitie | 1964 |
[THALIDOMIDE TERATOGENESIS IN CHICKS].
Topics: Abnormalities, Drug-Induced; Chick Embryo; Research; Teratogenesis; Thalidomide; Toxicology | 1964 |
[IMIDAZOLE AND THALIDOMIDE].
Topics: Abnormalities, Drug-Induced; Chemistry, Pharmaceutical; Imidazoles; Research; Thalidomide | 1964 |
[ON THE EFFECT OF THALIDOMIDE ON A CHICK EMBRYO].
Topics: Abnormalities, Drug-Induced; Chick Embryo; Research; Thalidomide; Toxicology | 1964 |
[HISTOCHEMICAL DIFFERENTIATION OF THE SKELETAL DEVELOPMENT OF EXTREMITIES].
Topics: Abnormalities, Drug-Induced; Bone and Bones; Dihydrolipoamide Dehydrogenase; Embryology; Enzymes; Ex | 1963 |
[STATISTICAL AND GENETIC RESEARCH ON CONGENITAL MALFORMATIONS. II. CONSIDERATIONS ON THE FREQUENCY OF CONGENITAL MALFORMATIONS OBSERVED AT THE ISTITUTO OSPITALIERO PROVINCIALE PER LA MATERNIT'A DI MILANO AMONG 85976 INFANTS BORN BETWEEN 1942 AND 1962].
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Genetic Research; Genetics, Medical; Humans; | 1964 |
THALIDOMIDE EMBRYOPATHY IN HYBRID RABBITS.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Extremities; Female; Fetal Diseases; Humans; K | 1964 |
THE USE OF SWINE IN DRUG TOXICITY STUDIES.
Topics: Abnormalities, Drug-Induced; Amphotericin B; Animals; Drug-Related Side Effects and Adverse Reaction | 1964 |
[RESEARCH ON THE TERATOGENIC EFFECT OF 2-DIETHYLAMINOPROPIOPHENONE].
Topics: Abnormalities, Drug-Induced; Animals; Diethylpropion; Female; Humans; Mice; Pregnancy; Rats; Researc | 1964 |
THE HANDICAPPED CHILD: 4 PHYSICAL HANDICAPS AND THE IMPORTANCE OF EARLY DIAGNOSIS.
Topics: Abnormalities, Drug-Induced; Clubfoot; Diagnosis; Disabled Persons; Early Diagnosis; Ectromelia; Inf | 1964 |
EFFECTS OF D,1-3-PHTHALIMIDOGLUTARIMIDE AND N-PHTHALYL-D,L-ASPARTIMIDE ON RAT PREGNANCY.
Topics: Abnormalities, Drug-Induced; Animals; Aspartic Acid; Female; Humans; Imides; Pharmacology; Phthalic | 1963 |
[APROPOS OF TERATOGENIC TESTS. SPONTANEOUS MALFORMATIONS IN RABBITS].
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Lagomorpha; Rabbits; Research; Terat | 1964 |
[ON POTENTIATION OF THE EMBRYOTOXIC EFFECTS OF THALIDOMIDE IN THE FEMALE RAT].
Topics: Abnormalities, Drug-Induced; Animals; Female; Humans; Pharmacology; Pregnancy; Rats; Research; Ribof | 1964 |
[METHODS AND PROBLEMS IN EXPERIMENTAL DRUG-INDUCED TERATOGENESIS].
Topics: Abnormalities, Drug-Induced; Animals; Drugs, Investigational; Female; Humans; Lagomorpha; Pregnancy; | 1964 |
[REPERCUSSIONS OF NEUROLEPTIC AND ANTITUMOR AGENTS ON PRENATAL DEVELOPMENT].
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Ant | 1964 |
AUTORADIOGRAPHIC INVESTIGATIONS OF 14-C-LABELLED THALIDOMIDE AND GLUTETHIMIDE IN PREGNANT MICE.
Topics: Abnormalities, Drug-Induced; Animals; Female; Glutethimide; Humans; Maternal-Fetal Exchange; Metabol | 1964 |
OCULAR DEFECTS IN THALIDOMIDE BABIES.
Topics: Abnormalities, Drug-Induced; Eye; Eye Diseases; Female; Humans; Infant; Infant, Newborn; Infant, New | 1964 |
EFFECTS OF THALIDOMIDE ON PREGNANCY IN THE RABBIT.
Topics: Abnormalities, Drug-Induced; Animals; Cell Biology; Embryo, Mammalian; Embryo, Nonmammalian; Female; | 1964 |
[THALIDOMIDE AND EAR-MALFORMATION].
Topics: Abnormalities, Drug-Induced; Ear, External; Humans; Infant; Pregnancy; Thalidomide; Toxicology | 1964 |
[ON THE FREQUENCY OF MALFORMATIONS IN BAVARIA. 2].
Topics: Abnormalities, Drug-Induced; Anencephaly; Cleft Lip; Cleft Palate; Clubfoot; Congenital Abnormalitie | 1964 |
PHARMACOLOGICAL PROPERTIES AND TERATOGENIC ACTION OF 2-(HEXAHYDROPHTHALIMIDO) GLUTARIMIDE AND 2-PHTHALIMIDO-N-METHYLGLUTARIMIDE.
Topics: Abnormalities, Drug-Induced; Animals; Female; Humans; Mice; Piperidines; Piperidones; Pregnancy; Pre | 1964 |
TERATOGENIC ACTIVITY OF THALIDOMIDE AND RELATED COMPOUNDS.
Topics: Abnormalities, Drug-Induced; Animals; Female; Humans; Pharmacology; Piperidines; Pregnancy; Rabbits; | 1964 |
THALIDOMIDE SYNDROME IN MONKEYS.
Topics: Abnormalities, Drug-Induced; Animals; Embryo Implantation; Extremities; Female; Fetus; Haplorhini; H | 1964 |
THALIDOMIDE INJURY TO AN IMPLANTED ARMADILLO BLASTOCYST.
Topics: Abnormalities, Drug-Induced; Animals; Armadillos; Embryo Implantation; Embryology; Extraembryonic Me | 1964 |
THE USE OF THALIDOMIDE AS TERATOGENIC AGENT IN RABBITS.
Topics: Abnormalities, Drug-Induced; Animal Experimentation; Animals; Ectromelia; Lagomorpha; Pathology; Rab | 1964 |
CONGENITAL ABSENCE OF THE TIBIA.
Topics: Abnormalities, Drug-Induced; Amputation, Surgical; Bone Diseases; Bone Transplantation; Child; Conge | 1964 |
[ON THE STATUS OF DYSMELIA IN BERLIN].
Topics: Abnormalities, Drug-Induced; Berlin; Biometry; Ectromelia; Extremities; Germany; Germany, West; Medi | 1964 |
VIRAL AND DRUG HAZARDS IN PREGNANCY.
Topics: Abnormalities, Drug-Induced; Androgens; Chickenpox; Congenital Abnormalities; Female; Hand Deformiti | 1964 |
EFFECT OF ACETYLSALICYLIC ACID ON FOETAL RATS.
Topics: Abnormalities, Drug-Induced; Aspirin; Caseins; Fetus; Pharmacology; Pregnancy; Rats; Research; Reser | 1964 |
HAZARDS OF OBSTETRICAL AND GYNECOLOGICAL DRUGS.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Androgens; Drug Therapy; Estrogens; Female; Gy | 1964 |
AMPUTATIONS, INCLUDING CONGENITAL ABNORMALITIES.
Topics: Abnormalities, Drug-Induced; Amputation Stumps; Amputation, Surgical; Artificial Limbs; Child; Ectro | 1964 |
[THALIDOMIDE-DAMAGED CHILDREN; EXPERIENCES IN THE EUGENIAHEMMET].
Topics: Abnormalities, Drug-Induced; Infant; Infant, Newborn; Thalidomide; Toxicology | 1964 |
[CHONDRODYSTROPHY AFTER THALIDOMIDE MEDICATION].
Topics: Abnormalities, Drug-Induced; Bone Diseases, Developmental; Drug Therapy; Ectromelia; Enchondromatosi | 1964 |
[EAR MALFORMATIONS IN THE FRAMEWORK OF THALIDOMIDE EMBRYOPATHY. (BASED ON A SURVEY OF 70 INFANTS BORN DURING 1959-1962)].
Topics: Abnormalities, Drug-Induced; Deafness; Ear Deformities, Acquired; Ear, External; Fetal Diseases; Hea | 1964 |
THALIDOMIDE-INDUCED APLASIA OF THE INNER EAR.
Topics: Abnormalities, Drug-Induced; Ear Deformities, Acquired; Ear, External; Ear, Inner; Facial Paralysis; | 1964 |
[THALIDOMIDE EMBRYOPATHY IN RABBITS FOLLOWING TRANSIENT LIVER DAMAGE IN THE MOTHER BY CARBON TETRACHLORIDE].
Topics: Abnormalities, Drug-Induced; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical | 1964 |
[ON THE PRENATAL TOXICITY OF DIPHENYLPYRALINE 8-CHLOROTHEOPHYLLINATE WITH REFERENCE TO EXPERIENCES WITH THALIDOMIDE AND CAFFEINE].
Topics: Abnormalities, Drug-Induced; Anti-Allergic Agents; Caffeine; Fetal Death; Histamine H1 Antagonists; | 1964 |
[MORAL MEDICAL ASPECTS OF CONGENITAL MALFORMATIONS].
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Ethics, Medical; Euthanasia; Humans; Infant, | 1964 |
MICROBIOLOGICALLY DETERMINED PANTOTHENIC ACID AND NICOTINIC ACID CONTENT OF CHICK EMBRYOS AFTER TREATMENT WITH THALIDOMIDE AND OF RAT FETUSES, NEWBORNS AND PLACENTAS FROM MOTHERS TREATED WITH THALIDOMIDE.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Biological Assay; Chick Embryo; Embryo, Mamm | 1964 |
[DRUGS WHICH SHOULD NOT BE GIVEN TO A PREGNANT WOMAN].
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Antineoplastic Agents; Dihydrostreptomycin Sul | 1964 |
THALIDOMIDE AND INDUCED AMPHIBIAN METAMORPHOSIS.
Topics: Abnormalities, Drug-Induced; Amphibians; Animals; Anura; Glutamine; Glutethimide; Metamorphosis, Bio | 1964 |
[EAR DEFORMATIONS RELATED TO THALIDOMIDE].
Topics: Abnormalities, Drug-Induced; Ear Deformities, Acquired; Ear, External; Infant, Newborn; Pregnancy; T | 1964 |
MORPHOLOGICAL AND PHYSIOLOGICAL EFFECTS OF THALIDOMIDE AND TRYPAN BLUE ON UTERI AND CONCEPTI OF GRAVID MICE.
Topics: Abnormalities, Drug-Induced; Amnion; Amniotic Fluid; Animals; Animals, Newborn; Ectromelia; Female; | 1965 |
[THALIDOMIDE AND CONGENITAL ABNORMALITIES OF THE EYE].
Topics: Abnormalities, Drug-Induced; Anophthalmos; Child; Eye Diseases; Infant; Learning; Microphthalmos; Op | 1964 |
[OCULOMOTOR PARALYSIS IN THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Female; Fetal Diseases; Ophthalmoplegia | 1964 |
[CONTERGAN INJURY WITH EYE INVOLVEMENT].
Topics: Abnormalities, Drug-Induced; Child; Eye Diseases; Female; Learning; Microphthalmos; Pregnancy; Prena | 1964 |
[THALIDOMIDE AND CONGENITAL ABNORMALITIES OF THE EYE].
Topics: Abnormalities, Drug-Induced; Child; Eye Diseases; Female; Learning; Microphthalmos; Pregnancy; Prena | 1964 |
[INDUCTION OF FETAL MALFORMATIONS IN RABBITS WITH THALIDOMIDE].
Topics: Abnormalities, Drug-Induced; Animals; Female; Humans; Lagomorpha; Pregnancy; Pregnancy, Animal; Rabb | 1964 |
THE MANAGEMENT OF UPPER LIMB DEFICIENCIES IN THE THALIDOMIDE-TYPE SYNDROME.
Topics: Abnormalities, Drug-Induced; Artificial Limbs; Disease Management; Prostheses and Implants; Syndrome | 1965 |
[THE PROCEDURES FOR THE TESTING OF TERATOGENIC EFFECTS TAKE SHAPE].
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Female; Haplorhini; Humans; Pregnancy; Sodium Chlori | 1965 |
[ON THE INCIDENCE OF MALFORMATIONS IN BAVARIA. 3].
Topics: Abnormalities, Drug-Induced; Biometry; Congenital Abnormalities; Ectromelia; Germany; Germany, West; | 1965 |
[PROBLEMS OF COMPARATIVE PATHOLOGY RELATIVE TO THALIDOMIDE].
Topics: Abnormalities, Drug-Induced; Biology; Thalidomide; Toxicology | 1964 |
CONGENITAL MALFORMATIONS IN A THALIDOMIDE BABY: A POSTMORTEM ANATOMICAL STUDY.
Topics: Abnormalities, Drug-Induced; Arm; Canada; Gallbladder Diseases; Infant; Kidney Diseases; Leg; Lung D | 1965 |
[ABNORMALITIES OF THE INTERNAL AND MIDDLE EAR AS A SEQUEL TO THALIDOMIDE EMBRYOPATHY--RESULTS OF TOMOGRAPHIC EXAMINATIONS OF THE EAR].
Topics: Abnormalities, Drug-Induced; Cochlear Nerve; Ear, Middle; Facial Nerve; Facial Paralysis; Fetal Dise | 1965 |
[TOMOGRAPHY IN LABYRINTH ABNORMALITIES].
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Ear, Inner; Labyrinth Diseases; Thalidomide; | 1965 |
[EMBRYOTOXIC EFFECTS IN RATS].
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Ethionamide; Female; Fetal Death; Hu | 1965 |
ANATOMY AND CLINICAL ASPECTS OF THE FACIAL NERVE.
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Anatomy; Ear; Facial Nerve; Facial Paralysis; Humans; O | 1965 |
[FETAL MALFORMATIONS PRODUCED BY THALIDOMIDE IN THE MOUSE].
Topics: Abnormalities, Drug-Induced; Animals; Female; Humans; Infant, Newborn; Mice; Pregnancy; Research; Th | 1964 |
RADIOGRAPHIC STUDIES OF THALIDOMIDE-INDUCED MALFORMATIONS IN MICE.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Ectromelia; Female; Humans; Kyphosis; | 1965 |
THALIDOMIDE EMBRYOPATHY AND LIMB DEFECTS; ESPERIENCES IN HABILITATION OF CHILDREN WITH ECTROMELIAS.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Angiography; Artificial Limbs; Child; Ectromel | 1965 |
PROBLEMS RAISED FOR THE FDA BY THE OCCURRENCE OF THALIDOMIDE EMBRYOPATHY IN GERMANY, 1960-1961.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Drug Industry; Female; Fetal Diseases; Germany | 1965 |
EFFECT OF SOME THERAPEUTIC AGENTS ON THE DEVELOPING RAT FETUS.
Topics: Abnormalities, Drug-Induced; Animals; Antipyrine; Aspirin; Chloral Hydrate; Dimenhydrinate; Female; | 1965 |
EFFECTS OF THALIDOMIDE ON FETAL DEVELOPMENT IN RABBITS AND ON ESTABLISHMENT OF PREGNANCY IN MONKEYS.
Topics: Abnormalities, Drug-Induced; Animals; Arthrogryposis; Extremities; Fetal Death; Fetal Development; F | 1965 |
TERATOGENIC EFFECTS OF THALIDOMIDE IN RABBITS, RATS, HAMSTERS, AND MICE.
Topics: Abnormalities, Drug-Induced; Animals; Avitaminosis; Cricetinae; Female; Humans; Mice; Pharmacology; | 1965 |
[ANATOMICAL FINDINGS OF THE SO-CALLED "THALIDOMIDE BABIES" WITH SPECIAL REFERENCE TO LIMBS].
Topics: Abnormalities, Drug-Induced; Ectromelia; Extremities; Female; Humans; Infant; Infant, Newborn; Mater | 1965 |
[GENETIC ACTIVITY OF THALIDOMIDE (P-PHTHALYLGLUTAMIC ACID IMIDE)].
Topics: Abnormalities, Drug-Induced; Animals; Drosophila; Genetic Therapy; Imides; Research; Thalidomide; To | 1965 |
[METHOD OF PRELIMINARY EVALUATION OF THE TERATOGENIC EFFECT OF DRUGS ON CHICK EMBRYOS].
Topics: Abnormalities, Drug-Induced; Chick Embryo; Research; Teratogenesis; Thalidomide; Toxicology | 1965 |
[ROENTGENOLOGIC CHANGES IN RABBIT THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Carbon Tetrachloride; Ectromelia; Fet | 1965 |
[RESEARCH ON SUBSTANCES STRUCTURALLY RELATED TO 2-PHTHALIMIDOGLUTARIMIDE (THALIDOMIDE)].
Topics: Abnormalities, Drug-Induced; Chemistry, Pharmaceutical; Imides; Pharmacy; Research; Thalidomide; Tox | 1965 |
APLASIA-HYPOPLASIA OF THE OTIC LABYRINTH AFTER THALIDOMIDE.
Topics: Abnormalities, Drug-Induced; Cochlear Nerve; Ear Canal; Ear Deformities, Acquired; Ear, External; Ea | 1965 |
[STUDIES ON THE PROBLEM OF HAND RIDGES AND CONFIGURATIONS IN ABNORMALITIES OF THE EXTREMITIES].
Topics: Abnormalities, Drug-Induced; Adolescent; Child; Dermatoglyphics; Ectromelia; Extremities; Hand; Huma | 1964 |
[THALIDOMIDE AND CLEFT LIP, JAW AND PALATE].
Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Female; Humans; Infant; Infant, Newborn; Pregn | 1965 |
[OUR CURRENT KNOWLEDGE ON EXTERNAL INJURIOUS INFLUENCES ON THE EMBRYO AND CONGENITAL DEFECTS].
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Drug Hypersensitivity; Knowledge; Thalidomide | 1964 |
EFFECT OF THALIDOMIDE WARNING ON MEDICINE PRESCRIBED FOR PREGNANT WOMEN. ANALYSIS OF FREE MEDICINES DELIVERED TO EXPECTANT MOTHERS IN THE VAESTERBOTTEN COUNTY OF SWEDEN DURING 1961 AND 1962.
Topics: Abnormalities, Drug-Induced; Animals; Female; Humans; Medicine; Mothers; Pregnancy; Prenatal Care; S | 1965 |
AN ATTEMPTED REVERSAL OF THALIDOMIDE EMBRYOPATHY IN THE RAT BY GLUTAMINE.
Topics: Abnormalities, Drug-Induced; Fetal Diseases; Glutamates; Glutamine; Pathology; Pharmacology; Pregnan | 1965 |
STUDIES ON THE EFFECT OF TRYPAN BLUE IN THE PREGNANT ARMADILLO, DASYPUS NOVEMCINCTUS.
Topics: Abnormalities, Drug-Induced; Animals; Armadillos; Blood Proteins; Female; Humans; Maternal-Fetal Exc | 1965 |
BIOCHEMICAL EFFECTS OF DRUGS ON THE MAMMALIAN CONCEPTUS.
Topics: Abnormalities, Drug-Induced; Animals; Blood; Electrophoresis; Embryology; Female; Glutamates; Humans | 1965 |
[ACTION OF THALIDOMIDE ON THE CHICK EMBRYO].
Topics: Abnormalities, Drug-Induced; Chick Embryo; Ectromelia; Extremities; Research; Thalidomide; Toxicolog | 1965 |
SKELETAL MALFORMATIONS IN THE HOLTZMAN RAT EMBRYO FOLLOWING THE ADMINISTRATION OF THALIDOMIDE.
Topics: Abnormalities, Drug-Induced; Animals; Bone Diseases; Female; Humans; Injections; Injections, Intrape | 1965 |
[THALIDOMIDE EMBRYOPATHY IN ANIMAL EXPERIMENT. REPRODUCTION OF THE THALIDOMIDE EMBRYOPATHY IN A TERATOLOGIC EXPERIMENT IN RABBITS WITH TRANSIENT LIVER DAMAGE].
Topics: Abnormalities, Drug-Induced; Animal Experimentation; Animals; Carbon Tetrachloride Poisoning; Female | 1964 |
[THE CONTRIBUTION OF EXPERIMENTAL ANIMAL STUDIES TO THE CLARIFICATION OF THE QUESTION OF RESPONSIBILITY IN THE CASE OF THALIDOMIDE (CONTERGAN) DAMAGE].
Topics: Abnormalities, Drug-Induced; Animal Experimentation; Animals; Animals, Laboratory; Drug Industry; Gu | 1964 |
[THE OCCURENCE OF DYSMELIA SYNDROMES IN THE SAAR REGION].
Topics: Abnormalities, Drug-Induced; Biometry; Germany; Germany, West; Infant, Newborn; Statistics as Topic; | 1965 |
[FETAL DAMAGE CAUSED BY PHARMACEUTICAL AGENTS].
Topics: Abnormalities, Drug-Induced; Endocrine System Diseases; Fetal Diseases; Humans; Morphine Dependence; | 1965 |
The return of thalidomide: new uses and renewed concerns.
Topics: Abnormalities, Drug-Induced; Global Health; Health Policy; Humans; Leprostatic Agents; Leprosy; Tera | 2003 |
On thalidomide and WHO policies.
Topics: Abnormalities, Drug-Induced; Global Health; Health Policy; Humans; Leprostatic Agents; Leprosy; Thal | 2003 |
Health of thalidomide victims and their progeny.
Topics: Abnormalities, Drug-Induced; Cause of Death; Child of Impaired Parents; Congenital Abnormalities; Fe | 2004 |
Effects of thalidomide on developmental, peri- and postnatal function in female New Zealand white rabbits and offspring.
Topics: Abnormalities, Drug-Induced; Abortifacient Agents; Animals; Animals, Newborn; Body Weight; Dose-Resp | 2004 |
Corneal endothelial abnormalities associated with thalidomide toxicity.
Topics: Abnormalities, Drug-Induced; Adult; Corneal Diseases; Ectromelia; Endothelium, Corneal; Humans; Male | 2005 |
Autism with ophthalmologic malformations: the plot thickens.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Autistic Disorder; Child; Child, P | 2004 |
[Surgical improvement of hearing in atresia auris congenita].
Topics: Abnormalities, Drug-Induced; Audiometry, Pure-Tone; Deafness; Ear, External; Female; Humans; Infant; | 1966 |
Carpal tunnel syndrome accompanying radial dysplasia due to thalidomide embryopathy.
Topics: Abnormalities, Drug-Induced; Adult; Carpal Tunnel Syndrome; Endoscopy; Female; Hand Deformities, Con | 2006 |
[Guideline for the appropriate use of thalidomide in the treatment of multiple myeloma].
Topics: Abnormalities, Drug-Induced; Dexamethasone; Drug Therapy, Combination; Humans; Informed Consent; Man | 2005 |
45 years later...where do we stand?
Topics: Abnormalities, Drug-Induced; Canada; Drug-Related Side Effects and Adverse Reactions; Female; Foreca | 2007 |
Thalidomide: the true story?
Topics: Abnormalities, Drug-Induced; Drama; Drug Industry; Germany; Humans; Television; Teratogens; Thalidom | 2007 |
Evaluation of the developmental toxicity of lenalidomide in rabbits.
Topics: Abnormalities, Drug-Induced; Animals; Embryonic Development; Female; Fetal Death; Fetus; Lenalidomid | 2007 |
New cases of thalidomide embryopathy in Brazil.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Adult; Brazil; Contraindications; | 2007 |
Thalidomide--the drama continues.
Topics: Abnormalities, Drug-Induced; Drug Industry; Germany; Humans; Interprofessional Relations; Motion Pic | 2007 |
[Contribution to the study of the fetal toxicity of thalidomide in the rat].
Topics: Abnormalities, Drug-Induced; Animals; Fetus; Rats; Thalidomide | 1966 |
[The significance of group B vitamins and genetic factors on the reaction of the rat embryo to thalidomide].
Topics: Abnormalities, Drug-Induced; Abnormalities, Severe Teratoid; Animals; Diet; Drug Hypersensitivity; E | 1966 |
[The teratogenic effect of thalidomide in experiments on chick embryos].
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Thalidomide | 1966 |
[Thalidomide embryopathy in animal experiments. II. Thalidomide blood level in experimental animals with normal and damaged liver].
Topics: Abnormalities, Drug-Induced; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Live | 1966 |
The embryotoxic effect on rabbits of monophenylbutazone (monazan) compared with phenylbutazone and thalidomide.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fertility; Fetal Death; Male; Phenylbutazone; Pregnanc | 1966 |
[On the teratogenic study of nirtomethaqualone of parnox].
Topics: Abnormalities, Drug-Induced; Animals; Mustard Compounds; Rats; Thalidomide; Tranquilizing Agents | 1966 |
The thalidomide embryopathy in hybrid rabbits.
Topics: Abnormalities, Drug-Induced; Animals; Cardiovascular Abnormalities; Digestive System Abnormalities; | 1967 |
Motor handicap in children: a study of a population in 1965.
Topics: Abnormalities, Drug-Induced; Adolescent; Arthritis, Juvenile; Brain Damage, Chronic; Cerebral Palsy; | 1967 |
[Otoneurological studies of facial nerve paralysis in thalidomide dysplasia].
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Child; Child, Preschool; Ear Deformities, Acquired; Ele | 1967 |
[On form and extent of hearing loss in ear deformities partially caused by thalidomide].
Topics: Abnormalities, Drug-Induced; Child; Child, Preschool; Craniofacial Dysostosis; Ear Deformities, Acqu | 1967 |
Non-teratogenicity of antituberculous drugs.
Topics: Abnormalities, Drug-Induced; Aminosalicylic Acids; Antitubercular Agents; Drug Synergism; Ethionamid | 1967 |
Effect of some therapeutic agents on the rabbit fetus.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Aspirin; Dimenhydrinate; Female; Fetus; Glut | 1967 |
LSD: effects on offspring.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetus; Lysergic Acid Diethylamide; Pregnancy; Pregnanc | 1967 |
The influence of thalidomide on the development of chick embryos cultivated in vitro.
Topics: Abnormalities, Drug-Induced; Adenosine Triphosphate; Animals; Brain; Chick Embryo; Culture Technique | 1967 |
Toxicity and teratogenicity of optical isomers of thalidomide.
Topics: Abnormalities, Drug-Induced; Animals; Chemical Phenomena; Chemistry, Physical; Female; Fetus; Hexoba | 1967 |
Chromosome changes in embryos treated with various teratogens.
Topics: Abnormalities, Drug-Induced; Animals; Chlorambucil; Chromosome Aberrations; Diet; Female; Hydroxyure | 1967 |
Teratogenic effects of the amino acid leucine in the chicken.
Topics: Abnormalities, Drug-Induced; Amnion; Animals; Animals, Newborn; Chick Embryo; Injections; Leg; Leuci | 1967 |
[Cleft lip and palate in thalidomide-induced embryopathies].
Topics: Abnormalities, Drug-Induced; Adult; Arm; Child; Child, Preschool; Cleft Lip; Cleft Palate; Ear Defor | 1967 |
The effect of thalidomide on the developing rat foetus.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Female; Pregnancy; Pregnancy, Animal; Rats; Thali | 1967 |
[The sensitivity period of thalidomide embryopathy in monkeys and humans].
Topics: Abnormalities, Drug-Induced; Animals; Female; Humans; Pregnancy; Thalidomide; Time Factors | 1967 |
[83 cases of deformity caused by thalidomide and its problems].
Topics: Abnormalities, Drug-Induced; Child, Preschool; Female; Humans; Infant; Japan; Male; Thalidomide | 1967 |
Effects of thalidomide treatment of inbred female mice on pregnancy, fetal development, and mortality of offspring.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Female; Fetal Death; Fetus; Mice; Pregnancy; Pre | 1967 |
Another, late thalidomide abnormality.
Topics: Abnormalities, Drug-Induced; Adult; Female; Humans; Maternal-Fetal Exchange; Pregnancy; Thalidomide; | 1981 |
Thalidomide: 20 years on.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Europe; Female; History, 20th Century; Humans; Male; | 1981 |
Studies on the hypothetical relationship of thalidomide-induced embryopathy and collagen biosynthesis.
Topics: Abnormalities, Drug-Induced; Animals; Collagen; Female; Hydroxyproline; Pregnancy; Procollagen-Lysin | 1981 |
Effect of thalidomide-derivatives on limb development in culture.
Topics: Abnormalities, Drug-Induced; Animals; Biotransformation; Extremities; Female; Limb Deformities, Cong | 1983 |
Classic illustration. Figure showing the relationship between malformations of the thalidomide type and the sales of thalidomide.
Topics: Abnormalities, Drug-Induced; Female; History, 20th Century; Humans; Infant, Newborn; Pregnancy; Thal | 1984 |
Embryotoxicity and teratogenicity of thalidomide in rats.
Topics: Abnormalities, Drug-Induced; Animals; Dimethylformamide; Eye Abnormalities; Female; Fetal Death; Pre | 1983 |
[Gynecological and endocrinological studies of thalidomide-damaged girls].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Amenorrhea; Female; Follicle Stimu | 1984 |
[Teratogenic action of Rifaximin in the rat and rabbit and its effect on perinatal development in the rat].
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetus; Hydroxyurea; Pregnancy; Prenatal Exposure Delay | 1984 |
Thalidomide deformities and their nerve supply.
Topics: Abnormalities, Drug-Induced; Animals; Axons; Extremities; Limb Deformities, Congenital; Rabbits; Sci | 1984 |
Differential inhibition of protein synthesis: a possible biochemical mechanism of thalidomide teratogenesis.
Topics: Abnormalities, Drug-Induced; Acylation; Animals; Chemical Phenomena; Chemistry; Cycloheximide; Embry | 1984 |
Clinical studies on teenage Brazilian victims of thalidomide.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Brazil; Child; Female; Gynecomasti | 1983 |
Platanna (Xenopus laevis) as a test organism for determining the embryotoxic effects of environmental chemicals.
Topics: Abnormalities, Drug-Induced; Animals; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Embr | 1984 |
Thalidomide teratogenesis: evidence for a toxic arene oxide metabolite.
Topics: Abnormalities, Drug-Induced; Animals; Biotransformation; Dose-Response Relationship, Drug; Epoxide H | 1981 |
Carbon fibre reinforced plastic applied to prosthetics and orthotics.
Topics: Abnormalities, Drug-Induced; Artificial Limbs; Carbon; Carbon Fiber; Humans; Orthotic Devices; Prost | 1981 |
Holt Oram syndrome mistaken for thalidomide embryopathy--embryological considerations.
Topics: Abnormalities, Drug-Induced; Adult; Diagnosis, Differential; Ectromelia; Female; Genetic Counseling; | 1982 |
[Teratogenic effect of drugs].
Topics: Abnormalities, Drug-Induced; Animals; Female; History, 16th Century; History, 17th Century; History, | 1982 |
Dissimilar effects of thalidomide in dizygotic twins.
Topics: Abnormalities, Drug-Induced; Adult; Brazil; Diseases in Twins; Ectromelia; Female; Humans; Pregnancy | 1980 |
[An examination programme for functional analysis of the upper extremities (author's transl)].
Topics: Abnormalities, Drug-Induced; Adult; Arm; Ectromelia; Female; Fingers; Humans; Male; Motor Skills; Mu | 1981 |
Fetal ear malformations induced by maternal ingestion of thalidomide in the bonnet monkey (Macaca radiata).
Topics: Abnormalities, Drug-Induced; Animals; Ear; Female; Gestational Age; Macaca radiata; Pregnancy; Thali | 1981 |
The thalidomide disaster briefly revisited.
Topics: Abnormalities, Drug-Induced; Ectromelia; Humans; Thalidomide | 1981 |
Congenital malformations surveillance: two American systems.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Data Collection; Humans; Methods; Thalidomide | 1981 |
The thalidomide embryopathy. An analysis from the UK.
Topics: Abnormalities, Drug-Induced; Humans; Infant, Newborn; Thalidomide; United Kingdom | 1981 |
[Consequences of unexpected drug effects, beginning with contergan studies by pediatrists].
Topics: Abnormalities, Drug-Induced; Acrodynia; Bacterial Infections; Child; Child, Preschool; Chloramphenic | 1981 |
[The situation of thalidomide-affected young people in choosing an occupation (author's transl)].
Topics: Abnormalities, Drug-Induced; Adolescent; Career Choice; Disability Evaluation; Ectromelia; Female; H | 1981 |
[Coincidence of a thalidomide-induced malformation and a lymphoma of high malignancy (author's transl)].
Topics: Abnormalities, Drug-Induced; Adolescent; Female; Humans; Lymphoma; Mediastinal Neoplasms; Pathology; | 1980 |
Causal inference in teratology.
Topics: Abnormalities, Drug-Induced; Alcoholic Beverages; Diazepam; Epidemiologic Methods; Female; Humans; I | 1980 |
Congenital short femur. Clinical, genetic and epidemiological comparison of the naturally occurring condition with that caused by thalidomide.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Child; Female; Femur; Hip Joint; Humans; Infant; Inf | 1980 |
Nonteratogenicity of a structural analog of thalidomide in pregnant baboons (Papio cynocephalus).
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Drug Evaluation, Preclinical; Female; P | 1980 |
A metabolite of a structural analog of thalidomide lacks teratogenic effect in pregnant rhesus monkeys.
Topics: Abnormalities, Drug-Induced; Animals; Drug Evaluation, Preclinical; Female; Macaca; Macaca mulatta; | 1980 |
Contraceptive efficacy.
Topics: Abnormalities, Drug-Induced; Contraception; Female; Humans; Isotretinoin; Pregnancy; Teratogens; Tha | 1995 |
Is thalidomide mutagenic?
Topics: Abnormalities, Drug-Induced; Animals; Child; Humans; Male; Mice; Mutagens; Salmonella; Thalidomide | 1995 |
Phantom limb experiences in congenital limb-deficient adults.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Arm; Artificial Limbs; Child; Ectromelia; Female; Hu | 1994 |
Evidence for teratogenicity of thalidomide using congenic and recombinant inbred rat strains.
Topics: Abnormalities, Drug-Induced; Alleles; Animals; Embryonic and Fetal Development; Female; Fetus; Genot | 1994 |
Thalidomide--the way forward.
Topics: Abnormalities, Drug-Induced; Erythema Nodosum; Humans; Leprosy, Lepromatous; Thalidomide | 1994 |
Thalidomide: 35 years on and still deforming.
Topics: Abnormalities, Drug-Induced; Brazil; Female; Humans; Infant, Newborn; Pregnancy; Thalidomide | 1994 |
Embryotoxic effects of thalidomide derivatives in the non-human primate callithrix jacchus. IV. Teratogenicity of micrograms/kg doses of the EM12 enantiomers.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Callithrix; Dose-Response Relationship, Drug; | 1994 |
Thalidomide embryopathy: revisited 27 years later.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Duane Retraction Syndrome; Eye Abnormal | 1993 |
The place of thalidomide in the treatment of inflammatory disease.
Topics: Abnormalities, Drug-Induced; Anti-Inflammatory Agents, Non-Steroidal; Contraindications; Cytokines; | 1996 |
A risk assessment of topical tretinoin as a potential human developmental toxin based on animal and comparative human data.
Topics: Abnormalities, Drug-Induced; Administration, Topical; Animals; Female; Humans; Isotretinoin; Keratol | 1997 |
Thalidomide, a current teratogen in South America.
Topics: Abnormalities, Drug-Induced; Female; Humans; Infant, Newborn; Leprostatic Agents; Leprosy; Male; Pre | 1996 |
Therapeutic Teratology: the 1996 Teratology Society Public Affairs Symposium.
Topics: Abnormalities, Drug-Induced; Female; Humans; Isotretinoin; Patient Education as Topic; Pregnancy; Te | 1996 |
Jekyll and Hyde: a new license for thalidomide?
Topics: Abnormalities, Drug-Induced; Acquired Immunodeficiency Syndrome; Antineoplastic Agents; Clinical Tri | 1997 |
The return of thalidomide: are birth defects surveillance systems ready?
Topics: Abnormalities, Drug-Induced; Child, Preschool; Female; Georgia; Humans; Infant; Infant, Newborn; Lim | 1997 |
Thalidomide: lack of mutagenic activity across phyla and genetic endpoints.
Topics: Abnormalities, Drug-Induced; Animals; Biotransformation; Cells, Cultured; CHO Cells; Chromosome Aber | 1997 |
Dominant gene probably caused some of defects ascribed to thalidomide.
Topics: Abnormalities, Drug-Induced; Child; Child, Preschool; Genes, Dominant; Humans; Teratogens; Thalidomi | 1998 |
[Misfortune at the beginning of life. Challenge and accomplishments].
Topics: Abnormalities, Drug-Induced; Heart Defects, Congenital; Humans; Infant, Newborn; Intensive Care Unit | 1998 |
A cautious comeback for thalidomide.
Topics: Abnormalities, Drug-Induced; Antineoplastic Agents; Graft vs Host Disease; HIV Wasting Syndrome; Hum | 1998 |
Was tumour necrosis factor-alpha responsible for the fetal malformations associated with thalidomide in the early 1960s?
Topics: Abnormalities, Drug-Induced; Antigens, CD; Female; Humans; Models, Biological; Pregnancy; Receptors, | 1998 |
Thalidomide.
Topics: Abnormalities, Drug-Induced; Adjuvants, Immunologic; AIDS-Related Opportunistic Infections; Anti-Inf | 1998 |
Does thalidomide cause second generation birth defects?
Topics: Abnormalities, Drug-Induced; Female; Humans; Pregnancy; Prenatal Exposure Delayed Effects; Thalidomi | 1998 |
A developmental model for thalidomide defects.
Topics: Abnormalities, Drug-Induced; Body Patterning; Ectoderm; Fibroblast Growth Factors; Humans; Limb Buds | 1998 |
Limb deficiencies identified by malformations surveillance programs.
Topics: Abnormalities, Drug-Induced; Humans; Limb Deformities, Congenital; Population Surveillance; Thalidom | 1998 |
Longitudinal limb deficiencies and the sclerotomes. An analysis of 378 dysmelic malformations induced by thalidomide.
Topics: Abnormalities, Drug-Induced; Bone and Bones; Humans; Infant; Limb Deformities, Congenital; Radiograp | 1999 |
Formed by thalidomide: mass torts as a false cure for toxic exposure.
Topics: Abnormalities, Drug-Induced; Canada; Europe; Female; Government Agencies; Humans; Japan; Legislation | 1997 |
Was the thalidomide tragedy preventable?
Topics: Abnormalities, Drug-Induced; Animals; Disease Models, Animal; Female; History, 20th Century; Humans; | 1998 |
Was the thalidomide tragedy preventable?
Topics: Abnormalities, Drug-Induced; Art; Ectromelia; Famous Persons; Female; History, 18th Century; Humans; | 1998 |
The puzzle of autism: an ophthalmologic contribution.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Autistic Disorder; Child; Eye Diseases; Facial Paral | 1998 |
Oxidative DNA damage and embryo development.
Topics: Abnormalities, Drug-Induced; Animals; Antioxidants; DNA Damage; Embryonic and Fetal Development; Fem | 1999 |
A possible role of N-cadherin in thalidomide teratogenicity.
Topics: Abnormalities, Drug-Induced; Animals; Cadherins; Chick Embryo; Models, Molecular; Molecular Structur | 2000 |
[The Contergan (Thalidomide) case. Catastrophic consequences].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Female; Humans; Hypnotics and Sedatives; Infan | 2000 |
The re-emergence of thalidomide: results of a scientific conference.
Topics: Abnormalities, Drug-Induced; Adjuvants, Immunologic; Adolescent; Adult; Anti-HIV Agents; Anti-Inflam | 2000 |
Specialist life - William McBride.
Topics: Abnormalities, Drug-Induced; Humans; Medicine; Obstetrics; Scientific Misconduct; Scopolamine; Speci | 2001 |
The rehabilitation of thalidomide.
Topics: Abnormalities, Drug-Induced; CD4 Lymphocyte Count; Conflict of Interest; Contraception; Drug Approva | 1998 |
Thalidomide's long and winding road.
Topics: Abnormalities, Drug-Induced; Clinical Trials as Topic; Drug Approval; Female; Health Services Access | 1998 |
Animal research. Various fallacies persist in vivisection debate.
Topics: Abnormalities, Drug-Induced; Animal Welfare; Animals; Bronchodilator Agents; Drug Evaluation, Precli | 2001 |
[The thalidomide story: the Israeli chapter].
Topics: Abnormalities, Drug-Induced; Antineoplastic Agents; Female; History, 20th Century; Humans; Israel; P | 2001 |
[On the history of the Contergan (thalidomide) catastrophe in the light of drug legislation].
Topics: Abnormalities, Drug-Induced; Animals; Drug Industry; Female; Fetus; France; Germany; History, 19th C | 2001 |
The redemption of thalidomide: standardizing the risk of birth defects.
Topics: Abnormalities, Drug-Induced; Birth Injuries; Drug and Narcotic Control; History, 20th Century; Human | 2000 |
Thalidomide, drug safety and early drug regulation in the UK.
Topics: Abnormalities, Drug-Induced; History, 20th Century; Humans; Legislation, Drug; State Medicine; Terat | 2001 |
Editorial: Postscript to thalidomide.
Topics: Abnormalities, Drug-Induced; Adult; Age Factors; Child; Child, Preschool; Ectodermal Dysplasia; Fema | 1975 |
Letter: Postscript to thalidomide.
Topics: Abnormalities, Drug-Induced; Female; Fetus; Humans; Maternal-Fetal Exchange; Pregnancy; Thalidomide | 1975 |
Letter: Neural crest, limb development, and thalidomide embryopathy.
Topics: Abnormalities, Drug-Induced; Animals; Arm; Ectromelia; Female; Fetus; Gestational Age; Haplorhini; H | 1976 |
Thalidomide and female genital malformations.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Ectromelia; Female; Genitalia, Fem | 1976 |
Thalidomide-type malformations and subsequent osteosarcoma.
Topics: Abnormalities, Drug-Induced; Adolescent; Arm; Femoral Neoplasms; Finland; Humans; Leg; Male; Osteosa | 1977 |
Teratogenic action of thalidomide.
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Ectromelia; Embryo, Mammalian; Female; Forelimb; | 1978 |
Agenesis of appendix: a further thalidomide anomaly.
Topics: Abnormalities, Drug-Induced; Adolescent; Appendix; Female; Humans; Maternal-Fetal Exchange; Pregnanc | 1978 |
Developmental staging and thalidomide teratogenicity in the green monkey (Cercopithecus aethiops).
Topics: Abnormalities, Drug-Induced; Animals; Chlorocebus aethiops; Female; Gestational Age; Haplorhini; Lim | 1978 |
Unusual muscle abnormalities associated with thalidomide treatment in a rhesus monkey: a case report.
Topics: Abnormalities, Drug-Induced; Animals; Female; Forearm; Haplorhini; Macaca mulatta; Muscles; Pregnanc | 1979 |
The use of in vitro procedures in teratology.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Aminopterin; Animals; Azaserine; Bromodeoxyuridine; | 1975 |
Partial unilateral cryptophthalmos with syndactyly, brachycephaly, and renal anomalies.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child, Preschool; Eye Abnormalities; Eyelids; | 1975 |
Thalidomide anomalies of the ear.
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Adolescent; Child; Deafness; Ear; Ear, External; Ear, I | 1976 |
Segmental embryonic peripheral neuropathy.
Topics: Abnormalities, Drug-Induced; Animals; Arm; Bone and Bones; Extremities; Humans; Leg; Limb Deformitie | 1975 |
The long search for the causes of congenital malformations in mammals.
Topics: Abnormalities, Drug-Induced; Animals; Cattle; Cattle Diseases; Humans; Polybrominated Biphenyls; Rab | 1978 |
A survey of thalidomide embryopathy in Taiwan.
Topics: Abnormalities, Drug-Induced; Female; Humans; Infant, Newborn; Male; Pregnancy; Taiwan; Thalidomide | 1977 |
Experimental aspects and clinical implications.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Chick Embryo; Congenital Abn | 1979 |
A conversation with Helen Taussig. Interview by Dr. W. Proctor Harvey.
Topics: Abnormalities, Drug-Induced; Cardiology; Education, Medical; Forecasting; Heart Defects, Congenital; | 1978 |
The state control of medicines: the first 3000 years.
Topics: Abnormalities, Drug-Induced; Drug Compounding; History, 18th Century; History, 19th Century; History | 1979 |
Thalidomide and lack of teratogenesis in Long-Evans rats.
Topics: Abnormalities, Drug-Induced; Animals; Female; Pregnancy; Rats; Thalidomide | 1979 |
The teratogenic activity of a thalidomide analogus EM12 in rats on a low-zinc diet.
Topics: Abnormalities, Drug-Induced; Animals; Diet; Female; Forelimb; Gestational Age; Male; Pregnancy; Rats | 1979 |
Teratologic evaluation of synthetic delta 9-tetrahydrocannabinol in rabbits.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Dronabinol; Eating; Female; Fetal Viability; Gest | 1979 |
[Scholastic and professional rehabilitation of patients with abnormalities of the upper extremities].
Topics: Abnormalities, Drug-Induced; Arm; Ectromelia; Female; Humans; Learning Disabilities; Male; Pregnancy | 1979 |
Drug and chemical effects on mother and child.
Topics: Abnormalities, Drug-Induced; Alcoholic Beverages; Contraceptive Agents, Female; Environmental Pollut | 1979 |
Teratogenicity of therapeutic agents.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Abortion, Induced; Anesthetics; Anima | 1979 |
[Development of the extremities in the embryo].
Topics: Abnormalities, Drug-Induced; Animals; Arm; Congenital Abnormalities; Female; Humans; Infant, Newborn | 1978 |
[Atypical retinal detachment in an adolescent with thalidomide abnormalities].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Female; Humans; Retinal Degenerati | 1977 |
[Serial studies in thalidomide damaged children].
Topics: Abnormalities, Drug-Induced; Adolescent; Humans; Mass Screening; Pigment Epithelium of Eye; Retinal | 1977 |
Two congenital neurological abnormalities caused by thalidomide.
Topics: Abnormalities, Drug-Induced; Adolescent; Brain Diseases; Female; Humans; Ophthalmoplegia; Thalidomid | 1977 |
Non-confirmation of thalidomide induced teratogenesis in rats and mice.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Resorption; Mice; Pharmaceutical Vehicles; Polys | 1977 |
The effect of thalidomide on a prosimian: the greater galago (Galago crassicaudatus).
Topics: Abnormalities, Drug-Induced; Animals; Female; Galago; Pregnancy; Thalidomide | 1977 |
Thalidomide and cranial nerve abnormalities.
Topics: Abnormalities, Drug-Induced; Child; Cranial Nerves; Humans; Paralysis; Thalidomide | 1978 |
Thalidomide and neurological damage revisited.
Topics: Abnormalities, Drug-Induced; Central Nervous System Diseases; Female; Fetus; Humans; Infant, Newborn | 1978 |
Poisoned people: psychotropic drugs in pregnancy: morphological and psychological adverse effects on offspring.
Topics: Abnormalities, Drug-Induced; Alcoholism; Behavior; Female; Fetal Alcohol Spectrum Disorders; Fetus; | 1978 |
Congenital aortic regurgitation observed in a thalidomide-deformed child.
Topics: Abnormalities, Drug-Induced; Adolescent; Aortic Valve Insufficiency; Arm; Echocardiography; Humans; | 1978 |
Editorial: Ocular teratogens: A commentary.
Topics: Abnormalities, Drug-Induced; Aminopterin; Child; Eye Abnormalities; Humans; Mercury; Thalidomide | 1975 |
Hemorrhage in development of the face.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Arteries; Craniofacial Dysostosis; Di | 1975 |
Unilateral and asymmetric limb defects in man: delineation of the femur-fibula-ulna complex.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Arm; Consanguinity; Femur; Fibula; Fingers; Ge | 1977 |
Evalulation of thalidomide children.
Topics: Abnormalities, Drug-Induced; Arm; Child; Femur; Hip Joint; Humans; Knee Joint; Leg; Radiography; Sho | 1977 |
Clinical observations on the thalidomide syndrome.
Topics: Abnormalities, Drug-Induced; Adolescent; Central Nervous System; Child; Female; Genitalia; Humans; L | 1977 |
[Epidemiology of congenital abnormalities].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Congenital Abnormalities; Epidemiologic Method | 1977 |
Agenesis of the vermiform appendix in a thalidomide child.
Topics: Abnormalities, Drug-Induced; Adolescent; Appendix; Female; Humans; Thalidomide | 1977 |
The spinal abnormalities in thalidomide embryopathy.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Child; Follow-Up Studies; Humans; | 1977 |
Linear growth of children with limb deformities following exposure to thalidomide in utero.
Topics: Abnormalities, Drug-Induced; Adolescent; Body Height; Child; Female; Growth; Humans; Limb Deformitie | 1977 |
Sclerotome subtraction: a radiologic interpretation of reduction deformities of the limbs.
Topics: Abnormalities, Drug-Induced; Bone and Bones; Extremities; Humans; Infant, Newborn; Limb Deformities, | 1977 |
Teratology study of two isoglutamine derivatives.
Topics: Abnormalities, Drug-Induced; Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Chemical Ph | 1976 |
Studies of the etiology of thalidomide dysmorphogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Axons; Extremities; Ganglia, Spinal; Limb Deformities, Congeni | 1976 |
[Teratogenic effect and stereospecificity of a thalidomide metabolite].
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Female; Fetus; Glutamates; Isomerism; Mi | 1976 |
Responses of pre-implantation mouse embryos to thalidomide exposure in utero.
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Embryonic Development; Female; Mice; Mitosi | 1976 |
[Genital malformations in thalidomide-damaged girls (author's transl)].
Topics: Abnormalities, Drug-Induced; Adolescent; Female; Genitalia, Female; Humans; Thalidomide; Uterus; Vag | 1976 |
[Problems of treating the clubhand in dysmelia syndrome (thalidomide-embryopathy)].
Topics: Abnormalities, Drug-Induced; Arthrodesis; Bone Development; Child; Follow-Up Studies; Forearm; Hand; | 1976 |
Predictiveness and limitations of test methods in teratology: overview.
Topics: Abnormalities, Drug-Induced; Animals; Drug Evaluation, Preclinical; Environmental Exposure; Female; | 1976 |
A clinical look at the problem of drugs in pregnancy and their effect on the fetus.
Topics: Abnormalities, Drug-Induced; Anesthesia, Obstetrical; Aspirin; Drug-Related Side Effects and Adverse | 1975 |
Congenital fusion of bones: radiology, embryology and pathogenesis.
Topics: Abnormalities, Drug-Induced; Bone and Bones; Bone Development; Carpal Bones; Cartilage; Child, Presc | 1975 |
Letter: Congenital malformations and embryonic neuropathy.
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Humans; Neurons; Peripheral Nerves; | 1975 |
The action of thalidomide on the peripheral nervous system of the embryo.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Embryo, Mammalian; Forelimb; Ganglia, Spinal | 1975 |
The pathogenesis of congenital malformations.
Topics: Abnormalities, Drug-Induced; Animals; Child; Extremities; Ganglia, Spinal; Humans; Infant, Newborn; | 1975 |
Teratogenesis.
Topics: Abnormalities, Drug-Induced; Alcoholism; Aminopterin; Animals; Anticonvulsants; Dose-Response Relati | 1976 |
The perception of teratogenic risk of cocaine.
Topics: Abnormalities, Drug-Induced; Abortion, Therapeutic; Cocaine; Counseling; Education, Medical; Female; | 1992 |
Thalidomide for systemic lupus erythematosus.
Topics: Abnormalities, Drug-Induced; Female; Humans; Lupus Erythematosus, Systemic; Pregnancy; Thalidomide | 1992 |
Comments on "Reply to 'Comments on "Moebius syndrome: animal model--human correlations and evidence for a brainstem vascular etiology"'".
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Brain Stem; Female; Humans; Pregnancy; Syndrom | 1992 |
Recognition of thalidomide defects.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Diagnosis, Differential; Head; Humans; Limb De | 1992 |
Thalidomide retrospective: what did the clinical teratologist learn?
Topics: Abnormalities, Drug-Induced; Female; Germany; History, 20th Century; Humans; Infant, Newborn; Pregna | 1992 |
The contributions of Widukind Lenz to teratology and science: comments on "Thalidomide retrospective: what did the clinical teratologist learn?".
Topics: Abnormalities, Drug-Induced; Female; Germany; History, 20th Century; Humans; Infant, Newborn; Pregna | 1992 |
A personal perspective on the thalidomide tragedy.
Topics: Abnormalities, Drug-Induced; Female; Germany; History, 20th Century; Humans; Infant, Newborn; Pregna | 1992 |
Congenital defects of the limbs and alcohol exposure in pregnancy: data from a population based study.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Alcoholism; Animals; British Columbia; Cocaine | 1992 |
The study of malformations "by the company they keep".
Topics: Abnormalities, Drug-Induced; Adult; Eye Abnormalities; Female; Humans; Male; Ocular Motility Disorde | 1992 |
Scientific fraud: the McBride case.
Topics: Abnormalities, Drug-Induced; Animals; Biomedical Research; Editorial Policies; Female; Humans; Infan | 1992 |
Refractive evaluation in thalidomide embryopathy.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Cornea; Eye Abnormalities; Female; Huma | 1992 |
Foetal life and a legal duty of care.
Topics: Abnormalities, Drug-Induced; Female; Fetus; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male | 1991 |
[Cocaine in pregnancy: a second Contergan?].
Topics: Abnormalities, Drug-Induced; Cocaine; Female; Humans; Infant, Newborn; Pregnancy; Risk Factors; Thal | 1990 |
Amelia: incidence and associated defects in a large population.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; British Columbia; Diagnosis, Differential; Ect | 1990 |
Research focuses on immunosuppressive effect, unknown teratogenic mechanism of thalidomide.
Topics: Abnormalities, Drug-Induced; Humans; Immunosuppression Therapy; T-Lymphocytes; Thalidomide | 1990 |
Comments on "Proposed Mechanisms of Action in Thalidomide Embryopathy".
Topics: Abnormalities, Drug-Induced; Humans; Limb Deformities, Congenital; Thalidomide | 1990 |
Comments on "Proposed Mechanisms of Action in Thalidomide Embryopathy".
Topics: Abnormalities, Drug-Induced; Humans; Limb Deformities, Congenital; Thalidomide | 1990 |
[Presacral meningocele in thalidomide-induced embryopathy].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Humans; Laminectomy; Male; Meningocele; | 1990 |
Induction of neural-tube defects in nonhuman primates.
Topics: Abnormalities, Drug-Induced; alpha-Fetoproteins; Animals; Female; Macaca mulatta; Neural Tube Defect | 1985 |
Clinical-epidemiologic assessment of pattern of birth defects associated with human teratogens: application to diabetic embryopathy.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Diabetes Mellitus, Type 1; Female; Georgia; H | 1989 |
[The education and occupational status of young adults damaged by thalidomide].
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Disability Evaluation; Education, Special; Female; G | 1989 |
Thalidomide, orogenital ulcers, and the risk of teratogenesis.
Topics: Abnormalities, Drug-Induced; Female; Genital Diseases, Female; Humans; Mouth Diseases; Risk; Thalido | 1985 |
Thalidomide, orogenital ulcers, and risk of teratogenicity.
Topics: Abnormalities, Drug-Induced; Female; Genital Diseases, Female; Humans; Pregnancy; Risk; Stomatitis, | 1985 |
Anaesthesia and thalidomide-related abnormalities.
Topics: Abnormalities, Drug-Induced; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean Section; | 1989 |
After the tragedy: living with the consequences.
Topics: Abnormalities, Drug-Induced; Attitude to Health; Disabled Persons; Female; Humans; Infant, Newborn; | 1988 |
On the ability of birth defects monitoring to detect new teratogens.
Topics: Abnormalities, Drug-Induced; Epidemiologic Methods; Humans; Infant, Newborn; Isotretinoin; Risk; Ter | 1987 |
Embryotoxic effects of thalidomide derivatives on the non-human primate Callithrix jacchus; 3. Teratogenic potency of the EM 12 enantiomers.
Topics: Abnormalities, Drug-Induced; Animals; Callithrix; Female; Pregnancy; Stereoisomerism; Thalidomide | 1988 |
Thalidomide retrospective: what did we learn?
Topics: Abnormalities, Drug-Induced; Female; Humans; Infant, Newborn; Pregnancy; Teratogens; Thalidomide | 1988 |
Thalidomide update: regulatory aspects.
Topics: Abnormalities, Drug-Induced; Female; Humans; Infant, Newborn; Legislation, Drug; Pregnancy; Teratoge | 1988 |
Prenatal diagnosis of thalidomide syndrome.
Topics: Abnormalities, Drug-Induced; Adult; Ectromelia; Female; Fetal Diseases; Humans; Pregnancy; Prenatal | 1987 |
Embryotoxic effects of thalidomide-derivatives in the non-human primate Callithrix jacchus. I. Effects of 3-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-dioxopiperidine (EM12) on skeletal development.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Callithrix; Dose-Response Relationship, Drug; | 1988 |
Pregnancy in women with thalidomide-induced disabilities. Case report and a questionnaire study.
Topics: Abnormalities, Drug-Induced; Adult; Cesarean Section; Ectromelia; Female; Humans; Infant, Newborn; P | 1988 |
Monitoring for multiple malformations in the detection of epidemics of birth defects.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Biometry; Female; Humans; Pregnancy; Rubella; | 1987 |
The value of case reports in human teratology.
Topics: Abnormalities, Drug-Induced; Animals; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Eryth | 1986 |
Preventive surgery for congenital deformities of the hand.
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Female; Fetus; Genetic Engineering; | 1985 |
[Detection and quantification of adverse reactions on the embryo and the fetus: studies and registries of congenital malformations].
Topics: Abnormalities, Drug-Induced; Ectromelia; Female; Humans; Pregnancy; Registries; Research Design; Spa | 1986 |
The role of cholinergic nerves in development.
Topics: Abnormalities, Drug-Induced; Animals; Extremities; Female; Humans; Limb Deformities, Congenital; Par | 1985 |
Thalidomide embryopathy in Germany, 1959-1961.
Topics: Abnormalities, Drug-Induced; Ectromelia; Female; Germany, West; Humans; Infant, Newborn; Male; Pregn | 1985 |
Temporomandibular malformations in the bonnet monkey (Macaca radiata) fetus following maternal ingestion of thalidomide.
Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Female; Fetus; Gestational A | 1985 |
On predicting environmentally-induced human reproductive hazards: an overview and historical perspective.
Topics: Abnormalities, Drug-Induced; Aminopterin; Animals; Dose-Response Relationship, Drug; Female; Humans; | 1985 |
[Teratogenic potentially of single dose of thalidomide in JW-NIBS rabbits].
Topics: Abnormalities, Drug-Induced; Anencephaly; Animals; Brain; Female; Heart Defects, Congenital; Hydroce | 1985 |
Blame, compensation and birth defects.
Topics: Abnormalities, Drug-Induced; Animals; Drug Evaluation; Drug Industry; Female; Humans; Infant, Newbor | 1985 |
[Adaptation problems in Neurosedyn-children. Evaluation of children's adaptation in home and school milieu along with the results of hand surgery].
Topics: Abnormalities, Drug-Induced; Child; Developmental Disabilities; Disabled Persons; Education, Special | 1971 |
Thalidomide and congenital Charcot's joints.
Topics: Abnormalities, Drug-Induced; Ankle; Arthrography; Arthropathy, Neurogenic; Bone and Bones; Child; Em | 1973 |
Letter: Thalidomide and embryonic neuropathy.
Topics: Abnormalities, Drug-Induced; Animals; Cervical Plexus; Female; Ganglia, Spinal; Pregnancy; Rabbits; | 1974 |
The susceptibility of the fetus and child to chemical pollutants. Chemicals in human teratogenesis and transplacental carcinogenesis.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Amphetamine; Androgens; Anticonvulsants; Antithyroid | 1974 |
Human experiences related to adverse drug reactions to the fetus or neonate from some maternally administered drugs.
Topics: Abnormalities, Drug-Induced; Antineoplastic Agents; Antithyroid Agents; Contraceptives, Oral; Diethy | 1972 |
[Congenital abnormalities of rectum and anus. Diagnosis, physiology and therapy].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anal Canal; Anus, Imperforate; Congenital Abno | 1971 |
Another chance for thalidomide?
Topics: Abnormalities, Drug-Induced; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Culture | 1966 |
Thalidomide.
Topics: Abnormalities, Drug-Induced; Anodontia; Child, Preschool; Female; Humans; Pregnancy; Thalidomide; To | 1965 |
Minor ocular abnormalities associated with thalidomide.
Topics: Abnormalities, Drug-Induced; Child, Preschool; Choroid; Eye Abnormalities; Female; Humans; Infant; I | 1966 |
Immunosuppression by thalidomide: implications for teratology.
Topics: Abnormalities, Drug-Induced; Abortion, Habitual; Female; Humans; Immunosuppressive Agents; Pregnancy | 1966 |
Effect of thalidomide on survival of skin homografts in rabbits.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Female; Immunosuppressive Agents; Pregn | 1966 |
Another chance for thalidomide?
Topics: Abnormalities, Drug-Induced; Animals; Poultry; Thalidomide | 1966 |
Perthes-like changes in thalidomide children.
Topics: Abnormalities, Drug-Induced; Child, Preschool; Humans; Infant; Infant, Newborn; Osteochondritis; Tha | 1967 |
Settlement of claims of thalidomide families.
Topics: Abnormalities, Drug-Induced; Drug Industry; Humans; Jurisprudence; Thalidomide; United Kingdom | 1968 |
Is lysergide a teratogen?
Topics: Abnormalities, Drug-Induced; Animals; Female; Lysergic Acid Diethylamide; Pregnancy; Rabbits; Specie | 1968 |
Damages awarded for thalidomide children.
Topics: Abnormalities, Drug-Induced; Child; England; Humans; Jurisprudence; Male; Thalidomide | 1969 |
Teratology.
Topics: Abnormalities, Drug-Induced; Amphibians; Animals; Chick Embryo; Congenital Abnormalities; Embryo, Ma | 1969 |
[Problems posed by the effects of medication on offspring].
Topics: Abnormalities, Drug-Induced; Animals; Dactinomycin; Female; Fetus; Glutethimide; Humans; Hypoglycemi | 1969 |
Appendicular skeletal and visceral malformations induced by thalidomide in bonnet monkeys.
Topics: Abnormalities, Drug-Induced; Animals; Arm; Bone and Bones; Brain; Dose-Response Relationship, Drug; | 1973 |
Embryonic neuropathy. A hypothesis of neural chest injury as the pathogenesis of congenital malformations.
Topics: Abnormalities, Drug-Induced; Animals; Cell Movement; Central Nervous System; Child; Cleft Palate; Co | 1974 |
The sensitive period and malformation syndrome produced by thalidomide in crab-eating monkey (Macaca fascicularis).
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Coccyx; Female; Femur; Fingers; Gestatio | 1973 |
Congenital lesions of the inner ear, demonstrated by tomography.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Adult; Child; Cochlea; Ear; Ear, I | 1974 |
Toxicologic studies of four fluorescent whitening agents.
Topics: Abnormalities, Drug-Induced; Animals; Dogs; Dose-Response Relationship, Drug; Drug Hypersensitivity; | 1974 |
Care of the handicapped child.
Topics: Abnormalities, Drug-Induced; Child; Child, Preschool; Disabled Persons; Humans; Rehabilitation; Thal | 1967 |
[Comparative studies on the problem of the further development disorders of the vertebral column in children with dysmelia syndrome and children with peromelia].
Topics: Abnormalities, Drug-Induced; Child; Child, Preschool; Diagnosis, Differential; Ectromelia; Female; H | 1967 |
[Dysmelia].
Topics: Abnormalities, Drug-Induced; Child; Child Guidance; Ectromelia; Education, Special; Humans; Thalidom | 1969 |
How thalidomide children see themselves.
Topics: Abnormalities, Drug-Induced; Body Image; Canada; Child; Disabled Persons; Female; Humans; Male; Thal | 1969 |
[Teratologic study of a new, structurally related to thalidomide, sedative-hypnotic effective compound (K-2004)].
Topics: Abdominal Muscles; Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Fetal Death; Her | 1969 |
A morphological and histochemical study of thalidomide-induced upper limb malformations in rabbit fetuses.
Topics: Abnormalities, Drug-Induced; Alkaline Phosphatase; Animals; Bone and Bones; Calcium; Cartilage; Embr | 1971 |
[Abnormalities in the field of otorhinolaryngology. Genetic report].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Acrocephalosyndactylia; Chromosome Aberrations | 1972 |
[Adaptation of extremely handicapped children, together with a report on the importance of early training of the motor apparatus].
Topics: Abnormalities, Drug-Induced; Adaptation, Physiological; Adaptation, Psychological; Child; Disabled P | 1972 |
[Malformations in otorhinolaryngology. Genetic report].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Chromosome Aberrations; Chromosome Diso | 1972 |
[Documentation and report on thalidomide damage].
Topics: Abnormalities, Drug-Induced; Activities of Daily Living; Child; Disability Evaluation; Documentation | 1973 |
[Growth in length of children damaged through thalidomide (author's transl)].
Topics: Abnormalities, Drug-Induced; Age Factors; Anthropometry; Arm; Body Height; Child; Child, Preschool; | 1974 |
[Proceedings: Changes of the shoulder joints in distal ectromelia in the scope of thalidomide embryopathy].
Topics: Abnormalities, Drug-Induced; Child; Ectromelia; Female; Germany, West; Humans; Male; Radiography; Sh | 1974 |
Tumour-incidence in progeny of thalidomide-treated mice.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Carcinoma, Hepatocellular; Female; Hodgkin D | 1967 |
Nicotinamide deficiency and thalidomide: potential teratogenic disturbances in Long-Evans rats.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Animal Feed; Animals; Birth Weight; Chlorproma | 1969 |
A histological and histochemical study of the development of the sternum in thalidomide-treated rats.
Topics: Abnormalities, Drug-Induced; Alkaline Phosphatase; Animals; Calcification, Physiologic; Calcium; Car | 1968 |
[Drug-induced polyneuropathy].
Topics: Abnormalities, Drug-Induced; Adult; Animals; Drug-Related Side Effects and Adverse Reactions; Female | 1970 |
[Genetic analysis of skeletal diseases. Genetic report].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Bone and Bones; Bone Diseases; Child; Chromoso | 1973 |
Pollicization for congenital deformities of the hand.
Topics: Abnormalities, Drug-Induced; Child; Child, Preschool; Fingers; Humans; Syndactyly; Tendons; Thalidom | 1973 |
Editorial: The pathogenesis of congenital malformations.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Female; Humans; Infant, Newborn; Pregnancy; P | 1974 |
Congenital malformations in nonhuman primates: spontaneous and experimentally induced.
Topics: Abnormalities, Drug-Induced; Aminopterin; Animals; Aspirin; Congenital Abnormalities; Female; Haplor | 1967 |
[Embryotoxicity of N-phthaloyl-DL-glutamine].
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Glutamine; Mice; Phthalic Acids; Pr | 1971 |
[Embryotoxic acitivity of N-phthaloyl-DL-isoglutamine].
Topics: Abnormalities, Drug-Induced; Animals; Drug Synergism; Female; Glutamine; Mice; Mice, Inbred Strains; | 1971 |
[Surgery of ear abnormalities (excluding the auricle)].
Topics: Abnormalities, Drug-Induced; Adrenergic beta-Antagonists; Anesthesia; Child; Congenital Abnormalitie | 1972 |
The dysplasias of the middle and the inner ear in different types of malformation.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Ear, Inner; Ear, Middle; Humans; Klippel-Feil | 1974 |
Fetal nerve cell degeneration produced by thalidomide in rabbits.
Topics: Abnormalities, Drug-Induced; Animals; Cell Nucleolus; Cell Nucleus; Dose-Response Relationship, Drug | 1974 |
Teratogenicity and embryotoxicity of thalidomide and 3-aza-thalidomide in mice.
Topics: Abnormalities, Drug-Induced; Animals; Aza Compounds; Body Weight; Bone and Bones; Depression, Chemic | 1974 |
Problems associated with the screening of drugs for possible teratogenic activity.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Animals; Aspirin; Dose-Response Rela | 1974 |
On the defect of digital creases.
Topics: Abnormalities, Drug-Induced; Child; Dermatoglyphics; Fetus; Humans; Thalidomide | 1974 |
[Teratological study on the thalidomide-like compounds K-2004 and K-2604 in the mouse and rat].
Topics: Abnormalities, Drug-Induced; Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Drug Evalua | 1974 |
Teratogenicity from drugs--an increasing problem.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Aminopterin; Amniocentesis; Animals; Anti-Bact | 1974 |
The significance of dermatoglyphics in medicine. A short survey and summary.
Topics: Abnormalities, Drug-Induced; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 13-15 | 1973 |
Some congenital abnormalities: possibly due to embryonic peripheral neuropathy.
Topics: Abnormalities, Drug-Induced; Child; Extremities; Female; Humans; Joints; Limb Deformities, Congenita | 1973 |
[Drugs as cause of diseases].
Topics: Abnormalities, Drug-Induced; Berlin; Contraceptives, Oral; Cortisone; Drug-Related Side Effects and | 1974 |
Monitoring adverse reactions to drugs: toward a therapeutic audit.
Topics: Abnormalities, Drug-Induced; Ambulatory Care; Analgesics; Anemia, Aplastic; Australia; Bibliographie | 1974 |
The teratogenic activity of a thalidomide analogue, EM 12 in rabbits, rats, and monkeys.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Bone Diseases, Developmental; Female; Fetal De | 1972 |
The marmoset as a model for teratological research.
Topics: Abnormalities, Drug-Induced; Animals; Estrus; Female; Haplorhini; Pregnancy; Thalidomide; Twins; Vit | 1972 |
Limb reduction anomalies induced in the marmoset by thalidomide.
Topics: Abnormalities, Drug-Induced; Animals; Ectromelia; Female; Haplorhini; Limb Deformities, Congenital; | 1972 |
Effects on macaque embryos of drugs reported or suspected to be teratogenic to humans.
Topics: Abnormalities, Drug-Induced; Aminopterin; Animals; Aspirin; Cesarean Section; Embryo, Mammalian; Fem | 1972 |
The marmoset as an animal model for teratological research.
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Disease Models, Animal; Female; Fetu | 1972 |
Defects and disabilities of thalidomide children.
Topics: Abnormalities, Drug-Induced; Arm; Child; Coloboma; Ear; Ectromelia; Eye Abnormalities; Heart Defects | 1973 |
Pharmacodynamic principles in chemical teratology: dose-effect relationships.
Topics: Abnormalities, Drug-Induced; Adsorption; Cyclophosphamide; Dose-Response Relationship, Drug; Drug-Re | 1972 |
Television programme no contempt.
Topics: Abnormalities, Drug-Induced; Child; Female; Humans; Jurisprudence; Pregnancy; Television; Thalidomid | 1972 |
Thalidomide injunction granted.
Topics: Abnormalities, Drug-Induced; Child, Preschool; Female; Humans; Jurisprudence; Newspapers as Topic; P | 1972 |
The effect of absence of thumb on palmar dermatoglyphics.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Dermatoglyphics; Hand Deformities, Congenital; | 1972 |
[Drug therapy in females of the reproductive age with reference to teratologic aspects].
Topics: Abnormalities, Drug-Induced; Age Factors; Aminopterin; Drug-Related Side Effects and Adverse Reactio | 1972 |
The use of an incubator in detecting drug-induced congenital malformations.
Topics: Abnormalities, Drug-Induced; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotra | 1972 |
Drugs and fetal development. Chairman's introductory address.
Topics: Abnormalities, Drug-Induced; Fetus; Thalidomide | 1972 |
Sporadic malformations in laboratory animals and their influence on drug testing.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Laboratory; Aspirin; Bone and Bones; Congenital Abnor | 1972 |
Drug testing for teratogenicity: its implications, limitations and application to man.
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Animals; Animals, Laboratory; Communication; Compute | 1972 |
Disabled children--free contraception for all? More liberal liquor laws?
Topics: Abnormalities, Drug-Induced; Adult; Alcoholism; Child; Contraception; Family Planning Services; Fema | 1973 |
Congenital malformations and their control.
Topics: Abnormalities, Drug-Induced; Animals; Dogs; Female; Humans; Mice; Pregnancy; Rats; Thalidomide | 1973 |
Moebius syndrome associated with the mother taking thalidomide during gestation. Case report.
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Abnormalities, Multiple; Anxiety; Facial Expression; Fa | 1973 |
The fetus: medicine's newest patient.
Topics: Abnormalities, Drug-Induced; Embryonic and Fetal Development; Female; Fetal Diseases; Fetus; Humans; | 1973 |
[Teratological tests of the hydrolysis products of thalidomide].
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetus; Gestational Age; Glutamates; Hydrolysis; Matern | 1973 |
Cardiovascular malformations in the chick embryo induced by thalidomide.
Topics: Abnormalities, Drug-Induced; Animals; Aortic Arch Syndromes; Aortic Valve Stenosis; Cardiovascular A | 1973 |
[Crocodile tears in thalidomide embryopathy].
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Child; Female; Humans; Male; Paralysis; Reflex, Abnorma | 1973 |
The effect of thalidomide intake during 113 human pregnancies.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Female; Gestational Age; Humans; Japan; Pregnanc | 1973 |
[The drama of thalidomide].
Topics: Abnormalities, Drug-Induced; Drug Industry; England; Germany, West; Humans; Jurisprudence; Sweden; T | 1973 |
Psychological test results of children with Thalidomide deformities.
Topics: Abnormalities, Drug-Induced; Activities of Daily Living; Adolescent; Canada; Child; Child, Preschool | 1973 |
Otological features in exomphalos-macro-glossia-gigantism syndrome (Wiedemann's syndrome).
Topics: Abnormalities, Drug-Induced; Adolescent; Audiometry; Deafness; Female; Gigantism; Hernia, Umbilical; | 1973 |
[Action of psychopharmacological agents on the product of conception].
Topics: Abnormalities, Drug-Induced; Amphetamine; Animals; Anticonvulsants; Embryo, Mammalian; Female; Fetal | 1973 |
[Morphological findings in surgically treated, bilateral, tibial aplasia].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Ankle; Ankle Joint; Autopsy; Child, Preschool; | 1973 |
[Research approaches and their promotion in the rehabilitation of amelic children].
Topics: Abnormalities, Drug-Induced; Child; Ectromelia; Germany, West; Humans; Research; Thalidomide | 1973 |
Thalidomide and critical period. Prescription for 113 pregnant women in a maternity.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Child; Female; Fetal Death; Fetus; Follow-Up Stu | 1973 |
Prospects and limitations of epidemiology in human teratology.
Topics: Abnormalities, Drug-Induced; Carcinogens; Chromosome Aberrations; Chromosome Disorders; Congenital A | 1973 |
First--cause no harm: an early warning system for iatrogenic disease.
Topics: Abnormalities, Drug-Induced; Computers; Ectromelia; Forecasting; Hospital Communication Systems; Med | 1973 |
[Surgical exploration of deafness due to thalidomide].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Audiometry; Child; Deafness; Ear; Ear, Inner; | 1974 |
Teratologic studies with FD and C red no. 2 in rats and rabbits.
Topics: Abnormalities, Drug-Induced; Animals; Autopsy; Body Weight; Cleft Palate; Coloring Agents; Female; F | 1974 |
Special prostheses.
Topics: Abnormalities, Drug-Induced; Athletic Injuries; Dentures; Facial Neoplasms; Humans; Lip; Mandibular | 1968 |
[The teratogenic risk].
Topics: Abnormalities, Drug-Induced; Animals; Azathioprine; Busulfan; Carbutamide; Congenital Abnormalities; | 1968 |
An award for Dr. William McBride.
Topics: Abnormalities, Drug-Induced; Australia; Awards and Prizes; France; History, 20th Century; Thalidomid | 1971 |
[The first description of the Widemann-Beckwith syndrome?].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adrenal Gland Diseases; Endocrinology; Hernia, | 1971 |
The rabbit thalidomide embryopathy.
Topics: Abnormalities, Drug-Induced; Animals; Biliary Tract; Digestive System Abnormalities; Eye Abnormaliti | 1966 |
The teratogenic activity of thalidomide in the rabbit.
Topics: Abnormalities, Drug-Induced; Animals; Eye Abnormalities; Female; Limb Deformities, Congenital; Nervo | 1966 |
Teratogenic agents and thalidomide.
Topics: Abnormalities, Drug-Induced; Coloboma; Eye Abnormalities; Female; Humans; Infant, Newborn; Male; Mic | 1966 |
'Thalidomide' syndrome in baboons.
Topics: Abnormalities, Drug-Induced; Animals; Haplorhini; Thalidomide | 1966 |
Ocular findings in thalidomide children.
Topics: Abnormalities, Drug-Induced; Blepharoptosis; Canada; Coloboma; Eye Abnormalities; Female; Humans; In | 1967 |
[On ocular malformations in the dysmelia syndrome].
Topics: Abnormalities, Drug-Induced; Child; Child, Preschool; Ectromelia; Eye Abnormalities; Female; Humans; | 1966 |
Drug toxicity in the animal fetus.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Cats; Cricetinae; Dogs; Embryo, Mammalian; Female; Fe | 1967 |
[Combination of eye and ear changes in the thalidomide induced syndrome of the 1st visceral arch].
Topics: Abnormalities, Drug-Induced; Branchial Region; Ear; Eye Abnormalities; Humans; Thalidomide | 1966 |
[Characteristics of the pathogenic effect of thalidomide on the various stages of development in the chick embryo].
Topics: Abnormalities, Drug-Induced; Animals; Anophthalmos; Brain; Chick Embryo; Eye Abnormalities; Gestatio | 1966 |
[A case of thalidomide anotia].
Topics: Abnormalities, Drug-Induced; Ataxia; Blepharoptosis; Child; Ear; Eye Abnormalities; Female; Humans; | 1967 |
[A comparison of the sensitive phase for thalidomide in animal experiment and in man].
Topics: Abnormalities, Drug-Induced; Animals; Arm; Ear; Female; Fetal Diseases; Haplorhini; Humans; Infant, | 1968 |
Toxicology: use of nonhuman primates.
Topics: Abnormalities, Drug-Induced; Animals; Central Nervous System; Drug-Related Side Effects and Adverse | 1967 |
Teratogeny in nonhuman primates, with notes on breeding procedures in Macaca mulatta.
Topics: Abnormalities, Drug-Induced; Androgens; Animals; Breeding; Chorionic Gonadotropin; Congenital Abnorm | 1969 |
[Thalidomide embryopathy with peculiar eye changes].
Topics: Abnormalities, Drug-Induced; Child; Ectodermal Dysplasia; Eye Abnormalities; Eye Manifestations; Fem | 1971 |
Teratologists united.
Topics: Abnormalities, Drug-Induced; Animals; Central Nervous System; Congenital Abnormalities; Genetics, Me | 1971 |
An investigation into the teratogenic potential of captan, folpet, and Difolatan in nonhuman primates.
Topics: Abnormalities, Drug-Induced; Animals; Antifungal Agents; Female; Fetus; Haplorhini; Humerus; Indoles | 1971 |
[Teratogenic effects induced by N-phthaloylglutamic acid imide in the maxillofacial region].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Animals, Newborn; Cleft Lip; Cleft Pa | 1971 |
Motor skills of infant rhesus monkeys with thalidomide-induced forelimb malformations.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Disease Models, Animal; Exploratory Behavior | 1969 |
[Social integration of dysmelic children caused by thalidomide in normal school classes].
Topics: Abnormalities, Drug-Induced; Ectromelia; Education; Germany, West; Public Opinion; Schools; Social A | 1972 |
[The Hamburg model for the education of thalidomide damaged children].
Topics: Abnormalities, Drug-Induced; Child; Education, Special; Germany, West; Humans; Rehabilitation Center | 1972 |
[Social integration of dysmelic children in special schools for the handicapped].
Topics: Abnormalities, Drug-Induced; Child; Ectromelia; Education, Special; Female; Humans; Male; Social Adj | 1972 |
[Scholastic achievement, intelligence and socioeconomic status of thadidomide-damaged children in regular school classes].
Topics: Abnormalities, Drug-Induced; Achievement; Child; Education; Educational Measurement; Educational Sta | 1972 |
[Diagnosis of malformations of the ear and temporal bone].
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Abnormalities, Multiple; Audiometry; Craniofacial Dysos | 1972 |
The treatment of radial club hand. Absent radius, aplasia of the radius, hypoplasia of the radius, radial paraxial hemimelia.
Topics: Abnormalities, Drug-Induced; Carpal Bones; Child, Preschool; Contracture; Hand; Hand Deformities, Co | 1972 |
Teratological studies on thalidomide in rats.
Topics: Abnormalities, Drug-Induced; Animals; Birth Weight; Body Weight; Bone and Bones; Cesarean Section; F | 1972 |
Teratological studies on thalidomide in rabbits.
Topics: Abnormalities, Drug-Induced; Animals; Autolysis; Birth Weight; Body Weight; Bone and Bones; Cesarean | 1972 |
Thalidomide teratology in swine: a preparatory study.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Bone and Bones; Female; Fetus; Gestation | 1972 |
Effects of thalidomide on the embryonic development of the axolotl (Ambystoma mexicanum).
Topics: Abnormalities, Drug-Induced; Ambystoma; Animals; Cell Differentiation; Cell Division; Edema; Heart R | 1972 |
[Supportive measures in dysmelic children in infancy].
Topics: Abnormalities, Drug-Induced; Age Factors; Child; Child Development; Child Health Services; Child, Pr | 1972 |
Michel's deafness.
Topics: Abnormalities, Drug-Induced; Child; Deafness; Ear Canal; Ear, Inner; Female; Humans; Pregnancy; Thal | 1972 |
Congenital heart disease in radial clubbed hand syndrome.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Female; Hand Deformities, Acquired; Heart Defe | 1971 |
[Compensation of the teratogenic effect of a thalidomide metabolite using L-glutamic acid].
Topics: Abnormalities, Drug-Induced; Animals; Drug Antagonism; Female; Glutamates; Injections, Intraperitone | 1971 |
[Suitability of silver fawn rabbits for toxicoloiical studies].
Topics: Abnormalities, Drug-Induced; Animals; Animals, Laboratory; Animals, Newborn; Rabbits; Species Specif | 1971 |
[Thalidomide-process in West Germany].
Topics: Abnormalities, Drug-Induced; Drug Industry; Germany, West; Humans; Jurisprudence; Thalidomide | 1971 |
[Malformation syndrome and urinary organs].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Child, Preschool; Chromosomes, Human, 1 | 1971 |
[Teratological determination of some thalidomide metabolites].
Topics: Abnormalities, Drug-Induced; Amides; Animals; Benzoates; Drug Interactions; Female; Fetus; Glutamate | 1971 |
[Cardiovascular findings in children with the thalidomide-dysmelia-syndrome].
Topics: Abnormalities, Drug-Induced; Child; Ectromelia; Female; Germany, West; Heart Defects, Congenital; Hu | 1971 |
The thumb in the congenital malformation syndromes.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Acrocephalosyndactylia; Anemia, Aplastic; Arm; | 1971 |
[Synostosis of the radius and scaphoid bone in hypoplasia of the thumb].
Topics: Abnormalities, Drug-Induced; Carpal Bones; Child; Congenital Abnormalities; Humans; Male; Radiograph | 1971 |
Congenital aural atresia: anatomy and surgical management.
Topics: Abnormalities, Drug-Induced; Chromosome Aberrations; Congenital Abnormalities; Ear; Female; Follow-U | 1971 |
[Thalidomide victims in a rehabilitation center].
Topics: Abnormalities, Drug-Induced; Nursing; Thalidomide | 1966 |
[Pediatricians' viewpoints on Contergan incidents].
Topics: Abnormalities, Drug-Induced; Nursing; Thalidomide | 1968 |
[Research and thalidomide children].
Topics: Abnormalities, Drug-Induced; Research; Thalidomide | 1969 |
[How thalidomide children see themselves].
Topics: Abnormalities, Drug-Induced; Body Image; Self Concept; Thalidomide | 1970 |
[Care study of an Isomin (thalidomide) child].
Topics: Abnormalities, Drug-Induced; Pediatric Nursing; Thalidomide | 1969 |
[Thalidomide incidents].
Topics: Abnormalities, Drug-Induced; Thalidomide | 1971 |
[Thalidomide-embryopathies and their effect on dentition].
Topics: Abnormalities, Drug-Induced; Ectromelia; Female; Humans; Infant, Newborn; Jaw Abnormalities; Pregnan | 1965 |
[Dysplasia in the mouth, jaw and teeth in dysmelia. Contribution to the thalidomide-embryopathies].
Topics: Abnormalities, Drug-Induced; Dental Caries; Ectromelia; Female; Humans; Infant, Newborn; Male; Pregn | 1967 |
[The dentition of a contergan child].
Topics: Abnormalities, Drug-Induced; Dentistry; Odontogenesis; Thalidomide | 1967 |
[Dysgnathias in the deciduous dentition in dysmelia: contribution to thalidomide embryopathy].
Topics: Abnormalities, Drug-Induced; Child; Child, Preschool; Dentition; Diastema; Ectromelia; Female; Human | 1966 |
[Cephalometric findings in dysmelic children with symptoms of thalidomide embryopathy].
Topics: Abnormalities, Drug-Induced; Cephalometry; Child; Child, Preschool; Female; Humans; Infant; Male; Mo | 1968 |
[It's not only contergan. In May the big lawsuit begins. It touches on basic problems].
Topics: Abnormalities, Drug-Induced; Drug Industry; Female; Forensic Medicine; Germany, West; Humans; Infant | 1968 |
Clinical, orthodontic and radiological findings in the jaws and face of children with dysmelia associated with thalidomide-embryopathy.
Topics: Abnormalities, Drug-Induced; Ankylosis; Cephalometry; Child, Preschool; Cleft Lip; Cleft Palate; Fem | 1968 |
"The induction of cleft palate in experimental animals with thalidomide".
Topics: Abnormalities, Drug-Induced; Cleft Palate; Dentistry; Thalidomide | 1969 |
Anomalies of the teeth in a child with upper phocomelia. Report of a case.
Topics: Abnormalities, Drug-Induced; Arm; Child; Ectromelia; Face; Female; Humans; Male; Pregnancy; Pregnanc | 1970 |
[The thalidomide drama].
Topics: Abnormalities, Drug-Induced; Artificial Limbs; Chemical Phenomena; Chemistry; Humans; Thalidomide | 1965 |
[Problems in retrospective and prospective studies of congenital anomalies].
Topics: Abnormalities, Drug-Induced; Humans; Prospective Studies; Retrospective Studies; Thalidomide | 1971 |
Tomography in inner and middle ear malformations: value, limits, results.
Topics: Abnormalities, Drug-Induced; Child; Child, Preschool; Cochlea; Ear; Ear Diseases; Ear Ossicles; Ear, | 1969 |
Conscious control of motor units with thalidomide children: an electromyographic study.
Topics: Abnormalities, Drug-Induced; Action Potentials; Child; Child, Preschool; Cybernetics; Electrodes; El | 1969 |
[The medical examination of children with malformations suspected to be due to thalidomide].
Topics: Abnormalities, Drug-Induced; Child; Ear Deformities, Acquired; Humans; Limb Deformities, Congenital; | 1969 |
[Possibilities, successes and failures of plastic operations in childhood].
Topics: Abnormalities, Drug-Induced; Humans; Infant; Kidney; Methods; Thalidomide; Ureter; Urinary Bladder; | 1969 |
[Characteristics of the action of medicinal substances on the fetus at various periods of intrauterine development].
Topics: Abnormalities, Drug-Induced; Animals; Anti-Bacterial Agents; Anticoagulants; Antimetabolites; Antine | 1969 |
Developmental biology.
Topics: Abnormalities, Drug-Induced; Biology; Cell Differentiation; Cortisone; DNA; Embryonic and Fetal Deve | 1969 |
[Teratologic studies with imipramine in rats and rabbits. Planning and interpretation of teratologic studies under consideration of the biochemistry and toxicology of test substance].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Body Weight; Desipramine; Drug Toleranc | 1969 |
[Congenital ear abnormalities as a cause of deafness].
Topics: Abnormalities, Drug-Induced; Animals; Anura; Cats; Chick Embryo; Congenital Abnormalities; Cricetina | 1969 |
Teratogenic activity of several phthalimide derivatives in the golden hamster.
Topics: Abnormalities, Drug-Induced; Animals; Chemical Phenomena; Chemistry; Cricetinae; Embryo, Mammalian; | 1970 |
Hand and foot preference in thalidomide children.
Topics: Abnormalities, Drug-Induced; Child; Functional Laterality; Humans; Thalidomide | 1970 |
Pollicisation in cases of radial club hand.
Topics: Abnormalities, Drug-Induced; Child; Female; Hand Deformities, Acquired; Humans; Male; Methods; Surge | 1970 |
The alimentary tract malformations in the rabbit thalidomide embryopathy.
Topics: Abnormalities, Drug-Induced; Animals; Colon; Digestive System Abnormalities; Diverticulum, Colon; Es | 1970 |
Malformation in the progeny of thalidomide-treated male rats.
Topics: Abnormalities, Drug-Induced; Animals; Breeding; Female; Male; Rats; Thalidomide | 1970 |
Thalidomide as a mutagenic agent in the mosquito (Culex pipiens molestus).
Topics: Abnormalities, Drug-Induced; Animals; Culex; Female; Genes, Lethal; Head; Male; Mosaicism; Mutagens; | 1970 |
Investigations on the possible teratogenic effects of trazodone in rats and rabbits.
Topics: Abnormalities, Drug-Induced; Animals; Cyclizine; Female; Maternal-Fetal Exchange; Piperazines; Pregn | 1970 |
Teratological studies of p-butoxyphenylacethydroxamic acid (CP 1044 J3) in rats and rabbits.
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Fetal Death; Hydroxamic Acids; Hydr | 1970 |
[Drug-induced chromosome aberrations].
Topics: Abnormalities, Drug-Induced; Animals; Chromosome Aberrations; Drug-Related Side Effects and Adverse | 1970 |
[The L-isomer as teratogenic principle of N-phthalyl-DL-glutamic acid].
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Fetal Death; Glutamates; Isotonic S | 1970 |
Congenital symmetric limb deformities.
Topics: Abnormalities, Drug-Induced; Arm; Black People; Congenital Abnormalities; Female; Humans; Infant, Ne | 1970 |
[Surgery in middle ear abnormalities].
Topics: Abnormalities, Drug-Induced; Child; Child, Preschool; Ear Ossicles; Ear, Middle; Ectromelia; Female; | 1970 |
[Fenestration surgery in ear abnormalities].
Topics: Abnormalities, Drug-Induced; Child; Child, Preschool; Ear Canal; Ear Ossicles; Ear, Middle; Ectromel | 1970 |
Roentgenographic changes in healed meningococcal labyrinthitis.
Topics: Abnormalities, Drug-Induced; Child; Deafness; Diagnosis, Differential; Ear, Inner; Humans; Labyrinth | 1970 |
[Skin ridges and skin furrows in dysmelia].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Child, Preschool; Chromosome Aberration | 1970 |
Further observations on the thalidomide embryopathy in rabbits.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Cytogenetics; Embryo, Mammalian; Fore | 1970 |
[Lesions of the auditory apparatus during pregnancy].
Topics: Abnormalities, Drug-Induced; Animals; Bacterial Infections; Deafness; Drug-Related Side Effects and | 1970 |
[Teratogenic effect of N-phthalyl-DL-glutamic acid following intraperitoneal application in mice].
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Fetus; Glutamates; Mice; Phthalic Acids; | 1970 |
[Study of the thalidomide effect on chick embryo].
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Eggs; Extremities; Female; Fetal Death; Pregnanc | 1970 |
[Intermolecular interaction of folic acid with N-phthaloyl-DL-glutamic acid. Teratogenic effect of thalidomide].
Topics: Abnormalities, Drug-Induced; Chemical Phenomena; Chemistry; Dioxins; Folic Acid; Solubility; Thalido | 1971 |
Chromosomal breakage and teratogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Antibiotics, Antineoplastic; Chromosome Aberrations; Chromosom | 1971 |
[The front line in research in experimental teratology].
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Female; Hominidae; Humans; Pregnancy | 1967 |
[Species differences in the metabolism of drugs].
Topics: Abnormalities, Drug-Induced; Animals; Dogs; Female; Mice; Pharmaceutical Preparations; Pregnancy; Ra | 1967 |
[Teratogenesis and drug control].
Topics: Abnormalities, Drug-Induced; Aminosalicylic Acids; Androgens; Animals; Chlordiazepoxide; Drug and Na | 1967 |
[Significance of exogenous influences for the development of human abnormalities].
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Female; Fetal Diseases; Humans; Infa | 1967 |
[Symposium on congential malformations. Introduction].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Congenital Abnormalities; Female; Humans; Infa | 1967 |
[Dysmelia from the view-point of the obstetrician].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Ectromelia; Female; Germany, East; Germany, We | 1967 |
[Malformation and liver damage. On the necessary 2nd noxa in experimental thalidomide embryopathies].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Carbon Tetrachloride; Chemical and Dr | 1967 |
[On methods and statistics in dysmelia research].
Topics: Abnormalities, Drug-Induced; Ectromelia; Factor Analysis, Statistical; Female; Health Surveys; Human | 1967 |
[Concluding remarks on the preceding comment by W. Lenz].
Topics: Abnormalities, Drug-Induced; Austria; Ectromelia; Female; Humans; Pregnancy; Thalidomide | 1967 |
[Remarks on the work of A. Rett: "The Thalidomide Problem in Austria" Wien. med. Wschr. (1965):21].
Topics: Abnormalities, Drug-Induced; Austria; Ectromelia; Female; Humans; Pregnancy; Thalidomide | 1967 |
[Abnormalities of internal organs in thalidomide embryopathy. A contribution to the determination of the sensitivity phase in thalidomide administration during early pregnancy].
Topics: Abnormalities, Drug-Induced; Adult; Digestive System Abnormalities; Ear Deformities, Acquired; Femal | 1967 |
[The genesis of congenital malformations].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Antineoplastic Agents; Cell Division; C | 1967 |
Drug testing in animals for fetal toxicity.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fertility; Fetus; Male; Pregnancy; Propylene Glycols; | 1967 |
Concerning the morphogeneis of thalidomide dysmelia in rabbits.
Topics: Abnormalities, Drug-Induced; Animals; Blood Vessels; Bone and Bones; Cell Differentiation; Ectromeli | 1967 |
[The so-called dysmelia syndrome (Thalidomide embryopathy) and its differential diagnosis].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Diagnosis, Differential; Ectromelia; Facial Ex | 1967 |
[The importance of psychology in the research on the etiology of dysmelia].
Topics: Abnormalities, Drug-Induced; Anxiety; Ectromelia; Female; Health Surveys; Humans; Maternal-Fetal Exc | 1967 |
[Inhibition of the immune reaction by thalidomide and the results of this process on the theory of the teratogenous effect of this substance].
Topics: Abnormalities, Drug-Induced; Animals; Female; Genes; Immunosuppressive Agents; Mice; Pregnancy; Thal | 1967 |
A comparison of the teratogenic activity of thalidomide in rabbits and rats.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Dimethyl Sulfoxide; Embryo Implantation; Femal | 1968 |
Congenital anomaly of the middle and inner ear.
Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Ear, Inner; Ear, Middle; Humans; Infant; Male; | 1968 |
Settlement for thalidomide babies.
Topics: Abnormalities, Drug-Induced; Humans; Infant, Newborn; Jurisprudence; Thalidomide | 1968 |
A Swedish register of congenital malformations. Experience with continuous registration during 2 years with special reference to multiple malformations.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Congenital Abnormalities; Female; Fetal Death; | 1968 |
The cardiovascular malformations in the rabbit thalidomide embryopathy.
Topics: Abnormalities, Drug-Induced; Animals; Aorta; Bronchial Arteries; Cardiovascular Abnormalities; Cardi | 1968 |
Thalidomide. A study of biochemical teratology.
Topics: Abnormalities, Drug-Induced; Amines; Animals; Chemistry, Pharmaceutical; Ectromelia; Embryo, Mammali | 1968 |
The susceptible period for thalidomide malformations in man and monkey.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Female; Humans; Monkey Diseases; Pregnancy; | 1968 |
[Action of thalidomide on the rate of malformations in rats with preformed genetic damage caused by malachite green].
Topics: Abnormalities, Drug-Induced; Aniline Compounds; Animals; Coloring Agents; Dwarfism; Female; Fetal De | 1968 |
Genetical, social, and medical aspects of abortion.
Topics: Abnormalities, Drug-Induced; Abortion, Criminal; Abortion, Legal; Abortion, Therapeutic; Adolescent; | 1968 |
[Angiography of atresia of the radius].
Topics: Abnormalities, Drug-Induced; Angiography; Child; Child, Preschool; Female; Humans; Infant; Male; Rad | 1968 |
[Prenatal and neonatal drug-induced lesions].
Topics: Abnormalities, Drug-Induced; Adult; Androgens; Drug-Related Side Effects and Adverse Reactions; Eryt | 1968 |
[On the incidence of congenital malformations of the central nervous system and the alimentary tract during the years 1950-61].
Topics: Abnormalities, Drug-Induced; Anal Canal; Anencephaly; Esophageal Atresia; Esophagus; Female; Hand De | 1968 |
[The induction of monstrosities by chemical substances and their explanation].
Topics: Abnormalities, Drug-Induced; Animals; Arsenicals; Chick Embryo; Colchicine; Congenital Abnormalities | 1968 |
[Thalidomide embryopathy in Japan].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Ear; Ectromelia; Female; Fetal Diseases; Finge | 1968 |
[Malformations].
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Embryology; Female; Fetal Diseases; | 1968 |
[Congenital metabolic diseases--thalidomide embryopathies].
Topics: Abnormalities, Drug-Induced; Animals; Child; Germany, West; Humans; Metabolism, Inborn Errors; Rabbi | 1968 |
[Chemotherapeutic fetopathy].
Topics: Abnormalities, Drug-Induced; Animals; Female; Humans; Hypnotics and Sedatives; Maternal-Fetal Exchan | 1968 |
Relationship between teratogeny and structure in the thalidomide field.
Topics: Abnormalities, Drug-Induced; Amides; Animals; Aortic Valve Stenosis; Chemical Phenomena; Chemistry; | 1968 |
Reconstructive surgery of major congenital skeletal deformities of the limbs.
Topics: Abnormalities, Drug-Induced; Amputation, Surgical; Child, Preschool; Fibula; Foot Deformities, Conge | 1969 |
Thalidomide claims.
Topics: Abnormalities, Drug-Induced; Child; Humans; Jurisprudence; Male; Thalidomide; United Kingdom | 1969 |
Teratogenicity of soporific drugs.
Topics: Abnormalities, Drug-Induced; Female; Glutethimide; Humans; Lysergic Acid Diethylamide; Mescaline; Ph | 1969 |
[Study of drug toxicity on the fetus].
Topics: Abnormalities, Drug-Induced; Animals; Drug-Related Side Effects and Adverse Reactions; Fetus; Mice; | 1964 |
[Thalidomide embryopathy. V. Kidney malformations].
Topics: Abnormalities, Drug-Induced; Female; Humans; Kidney; Pregnancy; Thalidomide | 1965 |
Persistent stapedial artery.
Topics: Abnormalities, Drug-Induced; Child, Preschool; Deafness; Ear Ossicles; Ear, Middle; Female; Humans; | 1965 |
Congenital short femur.
Topics: Abnormalities, Drug-Induced; Child, Preschool; Femur; Humans; Infant; Leg Length Inequality; Osteoto | 1965 |
Thalidomide teratogenesis in the developing chick embryo and its relationship to vitamin metabolism.
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Poultry Diseases; Thalidomide; Vitamins | 1965 |
[On the problems of thalidomide embryopathy].
Topics: Abnormalities, Drug-Induced; Ectromelia; Humans; Infant, Newborn; Thalidomide | 1965 |
Providing for their education.
Topics: Abnormalities, Drug-Induced; Artificial Limbs; Child; Education; Humans; Thalidomide | 1965 |
Susceptibility of certain inbred strains of hamsters to teratogenic effects of thalidomide.
Topics: Abnormalities, Drug-Induced; Animals; Breeding; Cricetinae; Female; Fetus; In Vitro Techniques; Preg | 1965 |
Embryotoxic activity of some pesticides and drugs related to phthalimide.
Topics: Abnormalities, Drug-Induced; Animals; Antifungal Agents; Chemical Phenomena; Chemistry; Female; Imid | 1965 |
Thalidomide malformations and genetic background in the rabbit.
Topics: Abnormalities, Drug-Induced; Animals; Female; Pregnancy; Rabbits; Thalidomide | 1965 |
[Animal experiments with thalidomide and a thalidomide-serum mixture].
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Ear Deformities, Acquired; Guinea Pigs; Immune S | 1965 |
Transplacental effects of drugs in mice.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Male; Maternal-Fetal Exchange; Methylcell | 1965 |
Teratogenetic properties of thalidomide.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Female; Humans; Pregnancy; Thalidomide | 1965 |
Thalidomide injury to the myocardium of armadillo embryos.
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Heart; Myocardium; Necrosis; Pregna | 1965 |
Thalidomide experience in Japan.
Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Ectromelia; Female; Humans; Infant, Newborn; J | 1965 |
[Disorders of induction and morphogenesis caused by drugs].
Topics: Abnormalities, Drug-Induced; Cell Differentiation; DNA; Embryo, Mammalian; Enzymes; Female; Genetic | 1965 |
[Conclusiveness of the thalidomide hypothesis].
Topics: Abnormalities, Drug-Induced; Ectromelia; Humans; Thalidomide | 1965 |
Teratogenicity studies.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Phenobarbital; Rabbits; Rats; Thalidomide | 1966 |
The thalidomide syndrome: comprehensive care.
Topics: Abnormalities, Drug-Induced; Child Care; Child, Preschool; Ectromelia; Humans; Infant; Rehabilitatio | 1966 |
[The experimental production of phocomelia in the chick embryo].
Topics: Abnormalities, Drug-Induced; Animals; Ectromelia; Mechlorethamine; Thalidomide | 1966 |
Medical and psychosocial aspects of the habilitation of thalidomide children.
Topics: Abnormalities, Drug-Induced; Adult; Artificial Limbs; Child, Preschool; Deafness; Ear Deformities, A | 1966 |
[Human genetic perspectives. Antenatal and perinatal exogenous disease causes].
Topics: Abnormalities, Drug-Induced; Asphyxia Neonatorum; Brain Diseases; Genetics, Medical; Humans; Infant, | 1966 |
Thalidomide: the case for legal action.
Topics: Abnormalities, Drug-Induced; Australia; Drug Industry; Female; Humans; Jurisprudence; Pregnancy; Tha | 1966 |
[Thalidomide-damaged children with multiple handicaps. The problem of diagnosis and rehabilitation].
Topics: Abnormalities, Drug-Induced; Female; Humans; Infant, Newborn; Pregnancy; Sweden; Thalidomide | 1966 |
Hazards to the newlyborn infant from thalidomide-containing drugs administered to pregnant mothers. (Report on three cases).
Topics: Abnormalities, Drug-Induced; Female; Humans; Infant; Limb Deformities, Congenital; Male; Pregnancy; | 1966 |
Teratological studies in the thalidomide field.
Topics: Abnormalities, Drug-Induced; Animals; Drug Synergism; Female; Fetal Death; Hexobarbital; Mice; Pregn | 1966 |
Early changes in limb buds of chick embryos after thalidomide treatment.
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Extremities; Microscopy, Electron; Thalidomide | 1966 |
[Considerations on the occurrence of human abnormalities].
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Environment; Environmental Exposure; Female; | 1966 |
[Results of systematic studies of 96 dysmelia children].
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Ectromelia; Humans; Infant; Thalidomide | 1966 |
[Thalidomide embryopathy in animal experiments. 3. Teratologic tests of thalidomide catabolic products].
Topics: Abnormalities, Drug-Induced; Animals; Encephalocele; Female; Glutamates; Glutamine; Phthalic Acids; | 1966 |
[Reference to central nervous system damage within the context of thalidomide embryopathy. Pathological-anatomic, electroencephalographic and neurologic findings].
Topics: Abnormalities, Drug-Induced; Central Nervous System Diseases; Child, Preschool; Ear Deformities, Acq | 1966 |
[Embryopathies and fetal diseases of therapeutic origin].
Topics: Abnormalities, Drug-Induced; Animals; Anti-Bacterial Agents; Anticoagulants; Antimalarials; Antineop | 1966 |
[Triphalangia of the thumb as a manifestation of thalidomide embryopathy].
Topics: Abnormalities, Drug-Induced; Child; Humans; Thalidomide; Thumb | 1966 |
[Toxic and teratogenic effects of thalidomide].
Topics: Abnormalities, Drug-Induced; Age Factors; Animals; Drug Synergism; Environmental Exposure; Female; G | 1966 |
[Development disturbances of the ductus and saccus endolymphaticus as causes of inner ear abnormalities].
Topics: Abnormalities, Drug-Induced; Child; Child, Preschool; Cochlea; Ear, Inner; Humans; Semicircular Cana | 1966 |
[Epidemiologic studies of malformations].
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Female; Germany, West; Humans; Infant Mortality; Inf | 1966 |