thalidomide has been researched along with Abnormalities, Congenital in 180 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The limb deformities in children commonly associated with the drug thalidomide are phocomelia and amelia." | 3.64 | Habilitation of patients with congenital malformations associated with thalidomide: prosthetic aspects. ( GILPIN, RE, 1963) |
| "The drug caused severe birth defects." | 2.58 | The changing health of Thalidomide survivors as they age: A scoping review. ( Atkin, K; Newbronner, E, 2018) |
| "Environmental causes of birth defects have increasingly been recognized since the mid-20th century." | 2.47 | Causes of birth defects: lessons from history. ( Lancaster, PA, 2011) |
| "Thalidomide was first synthesized in 1953 and was subsequently marketed as a mild hypnotic and sedative in more than 20 countries." | 1.34 | Living with thalidomide: health status and quality of life at 40 years. ( Bent, N; Chamberlain, MA; Neumann, V; Tennant, A, 2007) |
| "To evaluate the patterns of birth defects associated with diabetic embryopathy, a sensitivity-specificity analysis was performed on 4929 infants with major defects ascertained by the population-based Metropolitan Atlanta Congenital Defects Program between 1968 and 1980." | 1.28 | Clinical-epidemiologic assessment of pattern of birth defects associated with human teratogens: application to diabetic embryopathy. ( Becerra, JE; Cordero, JF; Erickson, JD; Khoury, MJ, 1989) |
| "The Metropolitan Atlanta Congenital Defects Programme (MACDP) is an intensive surveillance system using several methods to identify infants born with birth defects in the Atlanta area." | 1.26 | Congenital malformations surveillance: two American systems. ( Edmonds, LD; Erickson, JD; Flynt, JW; James, LM; Layde, PM; Oakley, GP, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 165 (91.67) | 18.7374 |
| 1990's | 3 (1.67) | 18.2507 |
| 2000's | 5 (2.78) | 29.6817 |
| 2010's | 7 (3.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ghassemi Jahani, SA | 1 |
| Danielsson, A | 1 |
| Karlsson, J | 1 |
| Brisby, H | 1 |
| Newbronner, E | 1 |
| Atkin, K | 1 |
| Weinrich, JM | 1 |
| Beyer, R | 1 |
| Well, L | 1 |
| Tahir, E | 1 |
| Lindemann, M | 1 |
| Wilke, U | 1 |
| Adam, G | 1 |
| Bannas, P | 1 |
| Lund, GK | 1 |
| PETERSEN, CE | 1 |
| Sales Luiz Vianna, F | 1 |
| Kowalski, TW | 1 |
| Fraga, LR | 1 |
| Sanseverino, MT | 1 |
| Schuler-Faccini, L | 1 |
| Klingberg, M | 1 |
| Lancaster, PA | 1 |
| Wadman, M | 1 |
| Strömland, K | 1 |
| Philipson, E | 1 |
| Andersson Grönlund, M | 1 |
| AIAZZI MANCINI, M | 1 |
| BERGSTROM, AL | 1 |
| NILSSON, L | 1 |
| PETTERSSON, G | 1 |
| SODERLING, B | 1 |
| VICTORIN, L | 1 |
| WINBERG, J | 2 |
| BLATTNER, RJ | 3 |
| HECHT, F | 1 |
| HOEFFLER, DF | 1 |
| SMITHELLS, RW | 3 |
| SOMERS, GS | 1 |
| SPEIRS, AL | 3 |
| TAUSSIG, HB | 3 |
| THIELE, S | 1 |
| TUCHMANN-DUPLESSIS, H | 7 |
| LAZURE, D | 1 |
| LECK, I | 1 |
| MILLAR, EL | 2 |
| LECUTIER, MA | 1 |
| LENZ, W | 4 |
| LINDEMANN, K | 1 |
| LUNING, KG | 1 |
| HELLGREN, K | 1 |
| LARSSON, KS | 2 |
| MASCITELLI-CORIANDOLI, E | 1 |
| MELLIN, GW | 1 |
| KATZENSTEIN, M | 1 |
| MURPHY, ML | 1 |
| PARKASH, O | 1 |
| GILPIN, RE | 1 |
| GIROUD, A | 1 |
| MERCIER-PAROT, L | 3 |
| HALL, JE | 1 |
| HEYNE, D | 1 |
| ISHIDA, M | 1 |
| SAITO, J | 1 |
| SAWAGUCHI, S | 1 |
| SATO, T | 1 |
| NAKAJO, S | 1 |
| HANAWA, M | 1 |
| JOKI, T | 1 |
| VAANANEN, I | 1 |
| FRANTZ, CH | 1 |
| GONZALEZ MENESES, A | 1 |
| HARKMARK, W | 1 |
| HAUPT, H | 1 |
| HIRSCH, W | 1 |
| KAJII, T | 2 |
| SHINOHARA, M | 1 |
| AUBERTIN, E | 1 |
| BASU, UP | 1 |
| BAYER, R | 1 |
| RAPOLA, J | 1 |
| ROSENDAL, T | 1 |
| SOMERS, GF | 1 |
| THOMAS, J | 1 |
| REITH, JF | 1 |
| ROVATI, AL | 1 |
| SHORB, MS | 1 |
| SMITH, C | 1 |
| VASAITIS, V | 1 |
| LUND, PG | 1 |
| POLLARD, W | 1 |
| SIEVERS, G | 1 |
| SOERGEL, W | 1 |
| SALZGEBER, B | 2 |
| SALAUN, J | 2 |
| UCHINO, S | 1 |
| NANJYO, N | 1 |
| UCHINO, H | 1 |
| SAKAGAWA, K | 1 |
| NARITA, T | 1 |
| WERTHEMANN, A | 1 |
| WILLIAMSON, AP | 1 |
| LUTZ, HR | 1 |
| YANG, TJ | 1 |
| YANG, TS | 1 |
| LIANG, HM | 1 |
| WEICKER, H | 1 |
| BACHMANN, KD | 1 |
| PFEIFFER, RA | 1 |
| GLEISS, J | 1 |
| WOOLLAM, DH | 1 |
| AARS, H | 1 |
| BOYLEN, JB | 1 |
| HORNE, HH | 1 |
| JOHNSON, WJ | 1 |
| CUTHBERT, R | 1 |
| DALMAU-CIRIA, M | 1 |
| KEMPER, F | 2 |
| KITTEL, G | 1 |
| KNAPP, K | 2 |
| ROBSON, JM | 1 |
| JAMES, JI | 1 |
| LAMB, DW | 1 |
| MATTURRI, L | 1 |
| NODARI, R | 1 |
| ROBECCHI, E | 1 |
| COHLAN, SQ | 1 |
| MONIE, IW | 1 |
| SCHIFINO, A | 1 |
| GRANA, E | 1 |
| SCHAUDIENST, R | 1 |
| MORIYAMA, Y | 1 |
| YANZON, NA | 1 |
| RODRIGUEZDEAGNESE, LR | 1 |
| MILDENSTEIN, F | 1 |
| RUETHER, K | 1 |
| PARTSCH, CJ | 2 |
| BIAGI, GL | 1 |
| FRANKLIN, AW | 1 |
| BPEOLCHINI, E | 1 |
| GINGRAS, G | 1 |
| MONGEAU, M | 1 |
| MOREAULT, P | 1 |
| DUPUIS, M | 1 |
| HEBERT, B | 1 |
| CORRIVEAU, C | 1 |
| ELSNER-MACKAY, P | 1 |
| SALLER, K | 2 |
| BUECHNER, F | 1 |
| SULAMAA, M | 1 |
| RYOEPPY, S | 1 |
| CONNELLY, JP | 1 |
| REYNOLDS, S | 1 |
| CRAWFORD, JD | 1 |
| TALBOT, NB | 1 |
| PAPPALEPORE, N | 1 |
| GOERTTLER, K | 1 |
| FREY, KW | 1 |
| INGALLS, TH | 1 |
| KLINGBERG, MA | 1 |
| LORKE, D | 1 |
| MAIER, W | 1 |
| JARVIK, LF | 1 |
| JOSEPH, MC | 1 |
| LECK, IM | 1 |
| MILLEN, JW | 1 |
| PLUM, P | 1 |
| RODIN, AE | 1 |
| KOLLER, LA | 1 |
| TAYLOR, JD | 1 |
| SAUNDERS, H | 1 |
| WRIGHT, R | 1 |
| HODGKIN, K | 1 |
| McBride, W | 1 |
| Bent, N | 1 |
| Tennant, A | 1 |
| Neumann, V | 1 |
| Chamberlain, MA | 1 |
| Goldman, AS | 1 |
| Edmonds, LD | 1 |
| Layde, PM | 1 |
| James, LM | 1 |
| Flynt, JW | 1 |
| Erickson, JD | 3 |
| Oakley, GP | 1 |
| Hook, EB | 1 |
| Regal, RR | 1 |
| Dally, A | 1 |
| Lary, JM | 1 |
| Daniel, KL | 1 |
| Roberts, HE | 1 |
| Moore, CA | 1 |
| Ances, BM | 1 |
| Bonta, I | 1 |
| McCredie, J | 3 |
| Loewenthal, J | 1 |
| Shepard, TH | 1 |
| Auroux, M | 1 |
| Schaller, A | 1 |
| Khoury, MJ | 1 |
| Becerra, JE | 1 |
| Cordero, JF | 1 |
| Smith, RJ | 1 |
| Schärli, AF | 1 |
| Shiono, H | 1 |
| Jörgensen, G | 2 |
| Fratta, ID | 1 |
| Wilson, JG | 3 |
| Gavan, JA | 1 |
| Zühlke, D | 1 |
| Mündnich, K | 1 |
| Bryan, EM | 1 |
| Kohler, HG | 1 |
| Shtenberg, AI | 1 |
| Illum, P | 1 |
| Holt, SB | 1 |
| Yager, JW | 1 |
| Kernis, MM | 1 |
| Poswillo, DE | 1 |
| Hamilton, WJ | 1 |
| Sopher, D | 1 |
| Palmer, AK | 1 |
| Kucera, J | 1 |
| Tuli, SM | 1 |
| Suzuki, M | 1 |
| Murai, N | 1 |
| Watanabe, G | 1 |
| Fradkin, R | 1 |
| Schönenberg, H | 1 |
| Poznanski, AK | 1 |
| Garn, SM | 1 |
| Holt, JF | 1 |
| Wulle, C | 1 |
| Nager, GT | 1 |
| Detenbeck, LC | 1 |
| Abrams, RC | 1 |
| Heine, W | 1 |
| Rett, A | 1 |
| Töndury, G | 1 |
| Källén, B | 1 |
| Gordon, H | 1 |
| Wolff, E | 1 |
| Kaiser, G | 1 |
| Henkel, L | 1 |
| Willert, HG | 1 |
| Piotrowski, J | 1 |
| Ciciliani, J | 1 |
| Tolks, H | 1 |
24 reviews available for thalidomide and Abnormalities, Congenital
| Article | Year |
|---|---|
The changing health of Thalidomide survivors as they age: A scoping review.
Topics: Aging; Comorbidity; Congenital Abnormalities; Disabled Persons; Female; Health Status; Humans; Menta | 2018 |
Causes of birth defects: lessons from history.
Topics: Abnormalities, Drug-Induced; Animals; Australia; Congenital Abnormalities; Female; Fever; History, 2 | 2011 |
THE PROBLEM OF TERATOGENICITY.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Cyclizine; Female; Imipramine; Nicotine; Preg | 1963 |
TERATOGENIC AGENTS AND CONGENITAL MALFORMATIONS.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Aminopterin; Congenital Abnormalities; Female; | 1963 |
[ABNORMALLY SHORTENED EXTREMITIES 1950-1962. RESULTS OF A SURVEY].
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Ear Deformities, Acquired; Ear, External; Ect | 1964 |
[CONGENITAL ABNORMALITIES CAUSED BY CHEMICAL AGENTS AND DEFICIENCIES. I].
Topics: Abnormalities, Drug-Induced; Alkaloids; Amino Acids; Anti-Bacterial Agents; Antibodies; Congenital A | 1964 |
[EXOGENOUS MALFORMATIONS].
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Alcohols; Androgens; Anesthetics; Congenital A | 1964 |
[ABNORMALITIES CAUSED BY TEMPORARY RESPIRATORY DISORDERS IN VERTEBRATES].
Topics: Animals; Autoradiography; Carbon Isotopes; Congenital Abnormalities; Decidua; Embryo, Mammalian; Emb | 1963 |
[ETIOPATHOGENESIS OF DEVELOPMENTAL DISORDERS. EXPERIMENTAL CONTRIBUTION TO THE CONCEPT OF PHENOCOPY].
Topics: Animals; Antimetabolites; Avitaminosis; Congenital Abnormalities; Hypoxia; Mammals; Pregnancy; Pregn | 1964 |
CONGENITAL MALFORMATIONS. CLINICAL AND COMMUNITY CONSIDERATIONS.
Topics: Abnormalities, Drug-Induced; Abnormalities, Severe Teratoid; Achondroplasia; Anencephaly; Cleft Pala | 1965 |
Critical periods of prenatal toxic insults.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Embryo, Mammalian; Female; Fetus; Gestational | 1980 |
Forms and causes of human malformations.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Estrogens; Fanconi Anemia; Female; Genes, Dom | 1980 |
The return of thalidomide: can birth defects be prevented?
Topics: Adult; Animals; Congenital Abnormalities; Female; Humans; Leprostatic Agents; Male; Pregnancy; Terat | 1999 |
New concerns about thalidomide.
Topics: Congenital Abnormalities; Drug Approval; Female; Guidelines as Topic; Humans; Infant, Newborn; Male; | 2002 |
Pathogenesis of congenital malformations. An hypothesis.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Congenital Abnormalities; Female; Ganglia, Spi | 1978 |
[Diseases and dermatoglyphics].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Bone and Bones; Chromosome Aberrations; Chromo | 1970 |
[Nutritional background and sensitivity of the organism to toxic substances].
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Diet; Dietary Carbohydrates; Dietary | 1972 |
The Mondini type of cochlear malformation. A survey of the literature.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Adult; Aged; Animals; Child, Presc | 1972 |
Congenital malformations and environmental influence: the occupational environment of laboratory workers.
Topics: Abnormalities, Drug-Induced; Anesthetics; Anti-Bacterial Agents; Benzene; California; Congenital Abn | 1973 |
Principles of teratology.
Topics: Abnormalities, Drug-Induced; Amniocentesis; Animals; Chromosome Aberrations; Chromosome Disorders; C | 1972 |
Abnormalities of intrauterine development in non-human primates.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Abortion, Spontaneous; Animals; Antineoplastic | 1972 |
Certain causes of congenital malformations in Homo sapiens and their prevention.
Topics: Abnormalities, Drug-Induced; Abortion, Therapeutic; Aminopterin; Antigen-Antibody Reactions; Chromos | 1967 |
[Fetal diseases caused by environmental polltuion].
Topics: Abnormalities, Drug-Induced; Air Pollution; Congenital Abnormalities; Environment; Environmental Pol | 1971 |
[Experimental epidemiology].
Topics: Animals; Chromosome Aberrations; Chromosome Disorders; Cleft Palate; Congenital Abnormalities; Diabe | 1971 |
156 other studies available for thalidomide and Abnormalities, Congenital
| Article | Year |
|---|---|
Middle-aged individuals with thalidomide embryopathy have undergone few surgical limb procedures and demonstrate a high degree of physical independence.
Topics: Abnormalities, Drug-Induced; Activities of Daily Living; Adult; Congenital Abnormalities; Female; Hu | 2017 |
Assessment of Congenital Vascular and Organ Anomalies in Subjects With Thalidomide Embryopathy Using Non-Contrast Magnetic Resonance Angiography.
Topics: Congenital Abnormalities; Creatinine; Female; Fetal Diseases; Gallbladder; Glomerular Filtration Rat | 2018 |
[Thalidomide and malformations. Contribution to the problem of the etiology of a frequently occurring malformation complex].
Topics: Congenital Abnormalities; Extremities; Hypnotics and Sedatives; Limb Deformities, Congenital; Thalid | 1962 |
The impact of thalidomide use in birth defects in Brazil.
Topics: Abnormalities, Multiple; Brazil; Congenital Abnormalities; Fetal Diseases; Humans; Leprosy; Teratoge | 2017 |
An epidemiologist's journey from typhus to thalidomide, and from the Soviet Union to Seveso.
Topics: Congenital Abnormalities; Crime; Disease Outbreaks; Epidemiology; History, 20th Century; Humans; Int | 2010 |
US lawsuit extends thalidomide's reach.
Topics: Animals; Chick Embryo; Congenital Abnormalities; Drug Industry; Ectromelia; Female; Humans; Liabilit | 2011 |
Offspring of male and female parents with thalidomide embryopathy: birth defects and functional anomalies.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Child; Child, Preschool; Congenital Abnormalities; F | 2002 |
[Thalidomide: a teratogenic drug?].
Topics: Congenital Abnormalities; Hypnotics and Sedatives; Teratogenesis; Teratogens; Thalidomide | 1962 |
[Thalidomide embryopathy].
Topics: Abnormalities, Multiple; Congenital Abnormalities; Fetal Diseases; Hypnotics and Sedatives; Syndrome | 1962 |
Drugs in pregnancy--thalidomide.
Topics: Congenital Abnormalities; Hypnotics and Sedatives; Pregnancy; Thalidomide | 1962 |
Thalidomide studies in experimental animals.
Topics: Congenital Abnormalities; Hypnotics and Sedatives; Thalidomide | 1962 |
The thalidomide babies.
Topics: Congenital Abnormalities; Hypnotics and Sedatives; Thalidomide | 1962 |
Thalidomide.
Topics: Congenital Abnormalities; Hypnotics and Sedatives; Thalidomide | 1962 |
Thalidomide and after.
Topics: Congenital Abnormalities; Humans; Hypnotics and Sedatives; Thalidomide | 1962 |
Thalidomide and malformations in Liverpool.
Topics: Congenital Abnormalities; Hypnotics and Sedatives; Thalidomide | 1962 |
Thalidomide and congenital abnormalities.
Topics: Congenital Abnormalities; Humans; Hypnotics and Sedatives; Thalidomide | 1962 |
Thalidomide and congenital abnormalities.
Topics: Congenital Abnormalities; Hypnotics and Sedatives; Thalidomide | 1962 |
Thalidomide--a lesson in remote effects of drugs.
Topics: Congenital Abnormalities; Hypnotics and Sedatives; Thalidomide | 1962 |
Phocomelia and thalidomide.
Topics: Congenital Abnormalities; Ectromelia; Hypnotics and Sedatives; Thalidomide | 1962 |
The thalidomide syndrome.
Topics: Congenital Abnormalities; Hypnotics and Sedatives; Thalidomide | 1962 |
Thalidomide abnormalities
Topics: Congenital Abnormalities; Hypnotics and Sedatives; Thalidomide | 1962 |
[Apropos of abnormalities attributed to a somnifacient: thalidomide].
Topics: Congenital Abnormalities; Fetus; Hypnotics and Sedatives; Thalidomide | 1962 |
Habilitation of patients with congenital malformations associated with thalidomide: psychiatric and psychological aspects.
Topics: Body Image; Canada; Child; Congenital Abnormalities; Humans; Medicine; Mental Disorders; Mothers; Pa | 1963 |
Short-term changes in the incidence of malformations.
Topics: Congenital Abnormalities; Incidence; Thalidomide | 1963 |
Phocomelia and internal defects due to thalidomide.
Topics: Congenital Abnormalities; Ectromelia; Humans; Thalidomide | 1962 |
[How can the physician prevent dangers for the offspring?].
Topics: Congenital Abnormalities; Ectromelia; Family; Pharmaceutical Preparations; Physicians; Radiation Gen | 1962 |
[On the prognosis and therapy of severe abnormalities of the extremities].
Topics: Artificial Limbs; Congenital Abnormalities; Ectromelia; Extremities; Prognosis; Prostheses and Impla | 1962 |
[Experiences in animal experimentation with drugs with suspected fetusdamaging effects].
Topics: Animal Experimentation; Animals; Congenital Abnormalities; Thalidomide | 1962 |
[The problem of thalidomide].
Topics: Congenital Abnormalities; Thalidomide | 1963 |
The saga of thalidomide. Neuropathy to embryopathy, with case reports of congenital anomalies.
Topics: Congenital Abnormalities; Fetal Diseases; Humans; Neurology; Peripheral Nervous System Diseases; Tha | 1962 |
Teratogenic effects in rats of growth inhibiting chemicals, including studies on thalidomide.
Topics: Animals; Antineoplastic Agents; Congenital Abnormalities; Humans; Male; Oligospermia; Rats; Teratoge | 1962 |
[Abnormalities caused by Contergan (thalidomide, N-phtalimido-glutarimide) in Drosophila melanogaster].
Topics: Animals; Congenital Abnormalities; Drosophila; Drosophila melanogaster; Piperidones; Thalidomide | 1962 |
Habilitation of patients with congenital malformations associated with thalidomide: prosthetic aspects.
Topics: Artificial Limbs; Child; Congenital Abnormalities; Ectromelia; Extremities; Humans; Medicine; Prosth | 1963 |
[Observatios on the teratogenic repercussions of thalidomide in the mouse and rabbit].
Topics: Animals; Congenital Abnormalities; Mice; Rabbits; Teratogenesis; Teratogens; Thalidomide | 1962 |
Habilitation of patients with congenital malformations associated with thalidomide: surgery of limb defects.
Topics: Adolescent; Amputees; Artificial Limbs; Child; Congenital Abnormalities; Ectromelia; Extremities; Hu | 1963 |
[Initial statistical elements relative to congenital malformations in Belgium].
Topics: Belgium; Biometry; Congenital Abnormalities; Diabetes Mellitus; Female; Humans; Pregnancy; Pregnancy | 1963 |
[Thalidomide deformities and their treatment].
Topics: Congenital Abnormalities; Thalidomide | 1963 |
[Thalidomide and embryopathies. Report of 2 cases].
Topics: Congenital Abnormalities; Fetal Diseases; Thalidomide | 1962 |
Increased incidence of malformed infants in West Germany during 1959-1962.
Topics: Congenital Abnormalities; Germany, West; Incidence; Thalidomide | 1963 |
[Thalidomide].
Topics: Congenital Abnormalities; Thalidomide | 1962 |
[Thalidomide and abnormalities].
Topics: Congenital Abnormalities; Thalidomide | 1962 |
[Nil nocere: Roentgen examination in pregnancy after thalidomide use?].
Topics: Abortion, Induced; Abortion, Spontaneous; Abortion, Therapeutic; Congenital Abnormalities; Female; H | 1962 |
Phocomelia.
Topics: Congenital Abnormalities; Ectromelia; Humans; Learning; Metabolic Diseases; Prenatal Exposure Delaye | 1963 |
Thalidomide in Japan.
Topics: Congenital Abnormalities; Japan; Thalidomide | 1963 |
[Thalidomide deformities].
Topics: Congenital Abnormalities; Humans; Thalidomide | 1963 |
[The thalidomide tragedies].
Topics: Congenital Abnormalities; Ectromelia; Euthanasia; Humans; Thalidomide | 1962 |
Thalidomide raises a problem in drug research.
Topics: Congenital Abnormalities; Drug Therapy; Humans; Pharmacology; Pyrrolidinones; Research; Thalidomide | 1962 |
[The significance of new exogenous noxae for the developmental damage of germ cells and ova and their prevention].
Topics: Abortion, Induced; Congenital Abnormalities; Ectromelia; Female; Fetal Death; Germ Cells; Iatrogenic | 1962 |
[Thalidomide and malformations].
Topics: Congenital Abnormalities; Thalidomide | 1962 |
Thalidomide and aplasia-hypoplasia of the otic labyrinth.
Topics: Congenital Abnormalities; Ear Deformities, Acquired; Ear, External; Ear, Inner; Labyrinth Diseases; | 1963 |
[Thalidomide and abnormalities of development].
Topics: Animals; Congenital Abnormalities; Female; Pregnancy; Pregnancy, Animal; Thalidomide | 1962 |
[Thalidomide dysplasias of the extremities and their concomitant abnormalities].
Topics: Congenital Abnormalities; Extremities; Hyperplasia; Thalidomide | 1962 |
[Role of external factors in the production of malformations].
Topics: Antineoplastic Agents; Avitaminosis; Congenital Abnormalities; Cortisone; Gonadal Steroid Hormones; | 1962 |
[Embryonal injury by toxic substances].
Topics: Congenital Abnormalities; Thalidomide; Veratrum; Veratrum Alkaloids | 1962 |
[The chronic toxicity of new synthetic drugs].
Topics: Alcohols; Barbiturates; Bemegride; Congenital Abnormalities; Glutethimide; Nitrofurans; Orotic Acid; | 1963 |
Effect of thalidomide treatment of hens on embryonic development and fertility.
Topics: Animals; Chickens; Congenital Abnormalities; Embryo, Mammalian; Embryo, Nonmammalian; Embryonic Deve | 1963 |
[Comments on the aetiology of the dysmelia syndrome].
Topics: Congenital Abnormalities; Ectromelia; Humans; Thalidomide | 1963 |
The incidence of limb and ear defects since the withdrawal of thalidomide.
Topics: Congenital Abnormalities; Ear Deformities, Acquired; Ear, External; Ectromelia; Incidence; Thalidomi | 1963 |
[On the increase in deformities of the extremities and external ear since 1960 with reference to exogenous factors].
Topics: Congenital Abnormalities; Ear Deformities, Acquired; Ear, External; Extremities; Female; Humans; Pre | 1962 |
Drug-induced malformations in the fetus.
Topics: Congenital Abnormalities; Fetus; Humans; Thalidomide | 1962 |
[Malformations of extremities obtained in the chick embryo after treatment by thalidomide].
Topics: Animals; Chick Embryo; Congenital Abnormalities; Extremities; Thalidomide | 1963 |
[Teratogenic action of thalidomide on the chick embryo, at different stages of development].
Topics: Animals; Chick Embryo; Congenital Abnormalities; Teratogenesis; Teratogens; Thalidomide | 1963 |
[Influence of increasing doses of glutethimide (Doriden) on pregnancy and fetal development in the rabbit].
Topics: Animals; Congenital Abnormalities; Female; Fetal Development; Glutethimide; Leadership; Pregnancy; P | 1963 |
[The teratogenic risk].
Topics: Congenital Abnormalities; Drug Therapy; Ectromelia; Risk; Teratogenesis; Teratogens; Thalidomide | 1963 |
[A case of phocomelia of the upper limbs probably induced by thalidomide].
Topics: Arm; Congenital Abnormalities; Ectromelia; Humans; Thalidomide; Upper Extremity | 1962 |
[General and special problems concerning the analysis of causes of malformations, especially thalidomide and aminopterin damages].
Topics: Aminopterin; Congenital Abnormalities; Ectromelia; Thalidomide | 1963 |
Abnormalities in chick embryos following thalidomide and other insoluble compounds in the amniotic cavity.
Topics: Amnion; Animals; Chick Embryo; Chorion; Congenital Abnormalities; Embryo, Mammalian; Embryo, Nonmamm | 1963 |
Thalidomide and congenital abnormalities.
Topics: Congenital Abnormalities; Thalidomide | 1963 |
[Thalidomide embryopathy. II. Results of individual anamnestic findings in the areas of inquiry of the universities of Bonn, Cologne, Muenster and Duesseldorf pediatric clinics].
Topics: Congenital Abnormalities; Fetal Diseases; Hypnotics and Sedatives; Research; Syndrome; Thalidomide; | 1962 |
Thalidomide disaster considered as an experiment in mammalian teratology.
Topics: Animals; Congenital Abnormalities; Disasters; Hypnotics and Sedatives; Mammals; Teratology; Thalidom | 1962 |
[Treatment of thalidomide children].
Topics: Congenital Abnormalities; Extremities; Thalidomide | 1963 |
Teratogenic effects of thalidomide and related substances.
Topics: Congenital Abnormalities; Thalidomide | 1963 |
Thalidomide induced malformations--a radiological survey.
Topics: Abnormalities, Multiple; Congenital Abnormalities; Data Collection; Radiology; Syndrome; Thalidomide | 1963 |
[Thalidomide and congenital abnormalities].
Topics: Congenital Abnormalities; Thalidomide | 1962 |
[Chick egg embryopathy].
Topics: Animals; Chickens; Congenital Abnormalities; Fetal Diseases; Thalidomide | 1963 |
[Abnormalities of the visceral arch with reference to the developmental history and influences of Contergan].
Topics: Branchial Region; Congenital Abnormalities; Craniofacial Dysostosis; Humans; Thalidomide | 1963 |
[Studies on Thalidomide as a cause of congenital malformations].
Topics: Congenital Abnormalities; Humans; Thalidomide | 1963 |
CONGENITAL ABNORMALITIES OF THE LIMBS.
Topics: Arm; Congenital Abnormalities; Ectromelia; Extremities; Foot Diseases; Hand Deformities; Hip Disloca | 1963 |
[ANATOMOCLINICAL STUDY OF 19 CASES OF EMBRYOPATHY CAUSED BY THALIDOMIDE].
Topics: Appendix; Congenital Abnormalities; Ectromelia; Female; Fetal Diseases; Heart Defects, Congenital; H | 1963 |
[MEDICAL THERAPY IN PREGNANCY AND ITS REPERCUSSIONS ON THE FETUS].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Androgens; Anti-Bacterial Agents; Anticoagulan | 1963 |
INFLUENCE OF THE ENVIRONMENT ON THE UNBORN.
Topics: Abnormalities, Drug-Induced; Aminopterin; Animals; Communicable Diseases; Congenital Abnormalities; | 1963 |
[EXPERIMENTAL CONTRIBUTION TO THE STUDY OF FETAL MALFORMATIONS CAUSED BY DRUGS].
Topics: Animals; Congenital Abnormalities; Lagomorpha; Rabbits; Research; Thalidomide; Toxicology | 1963 |
[POSSIBILITIES OF AID ACCORDING TO FEDERAL LEGISLATION ON SOCIAL ASSISTANCE FOR SUBJECTS WITH SEVERE ABNORMALITIES WITH SPECIAL REFERENCE TO REHABILITATION FOR THE HANDICAPPED].
Topics: Abnormalities, Drug-Induced; Artificial Limbs; Congenital Abnormalities; Disabled Persons; Germany; | 1963 |
[CONGENITAL MALFORMATIONS IN JAPAN].
Topics: Abnormalities, Drug-Induced; Classification; Congenital Abnormalities; Infant, Newborn; Japan; Pregn | 1963 |
[COMMENTARIES ABOUT 107 CONGENITAL MALFORMATIONS].
Topics: Abnormalities, Drug-Induced; Aminopterin; Chromosome Aberrations; Chromosome Disorders; Congenital A | 1963 |
[EAR DEFORMITIES IN THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Drug-Induced; Cleft Palate; Congenital Abnormalities; Cryptorchidism; Ear Deformities | 1964 |
THE CHILD WITH CONGENITAL LIMB DEFORMITIES.
Topics: Abnormalities, Drug-Induced; Achondroplasia; Arm; Congenital Abnormalities; Ectromelia; Education; F | 1964 |
[STATISTICAL AND GENETIC RESEARCH ON CONGENITAL MALFORMATIONS. II. CONSIDERATIONS ON THE FREQUENCY OF CONGENITAL MALFORMATIONS OBSERVED AT THE ISTITUTO OSPITALIERO PROVINCIALE PER LA MATERNIT'A DI MILANO AMONG 85976 INFANTS BORN BETWEEN 1942 AND 1962].
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Genetic Research; Genetics, Medical; Humans; | 1964 |
CONGENITAL ANOMALIES OF THE LIMBS: II. PSYCHOLOGICAL AND EDUCATIONAL ASPECTS.
Topics: Adaptation, Psychological; Adolescent; Artificial Limbs; Biomedical Research; Body Image; Canada; Ch | 1964 |
[APROPOS OF TERATOGENIC TESTS. SPONTANEOUS MALFORMATIONS IN RABBITS].
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Lagomorpha; Rabbits; Research; Terat | 1964 |
[ON THE FREQUENCY OF MALFORMATIONS IN BAVARIA. 2].
Topics: Abnormalities, Drug-Induced; Anencephaly; Cleft Lip; Cleft Palate; Clubfoot; Congenital Abnormalitie | 1964 |
CONGENITAL ABSENCE OF THE TIBIA.
Topics: Abnormalities, Drug-Induced; Amputation, Surgical; Bone Diseases; Bone Transplantation; Child; Conge | 1964 |
VIRAL AND DRUG HAZARDS IN PREGNANCY.
Topics: Abnormalities, Drug-Induced; Androgens; Chickenpox; Congenital Abnormalities; Female; Hand Deformiti | 1964 |
[MORAL MEDICAL ASPECTS OF CONGENITAL MALFORMATIONS].
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Ethics, Medical; Euthanasia; Humans; Infant, | 1964 |
[ON THE INCIDENCE OF MALFORMATIONS IN BAVARIA. 3].
Topics: Abnormalities, Drug-Induced; Biometry; Congenital Abnormalities; Ectromelia; Germany; Germany, West; | 1965 |
[TOMOGRAPHY IN LABYRINTH ABNORMALITIES].
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Ear, Inner; Labyrinth Diseases; Thalidomide; | 1965 |
[EMBRYOTOXIC EFFECTS IN RATS].
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Ethionamide; Female; Fetal Death; Hu | 1965 |
[OUR CURRENT KNOWLEDGE ON EXTERNAL INJURIOUS INFLUENCES ON THE EMBRYO AND CONGENITAL DEFECTS].
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Drug Hypersensitivity; Knowledge; Thalidomide | 1964 |
Congenital malformations attributed to sleeping pill (Thalidomide).
Topics: Congenital Abnormalities; Hypnotics and Sedatives; Thalidomide | 1962 |
Thalidomide and congenital abnormalities.
Topics: Congenital Abnormalities; Humans; Hypnotics and Sedatives; Thalidomide | 1962 |
[Thalidomide and development of the chick embryo].
Topics: Congenital Abnormalities; Embryo, Mammalian; Embryo, Nonmammalian; Hypnotics and Sedatives; Thalidom | 1962 |
Incidence of malformations since the introduction of thalidomide.
Topics: Congenital Abnormalities; Hypnotics and Sedatives; Incidence; Thalidomide | 1962 |
[Thalidomide embryopathy].
Topics: Congenital Abnormalities; Fetal Diseases; Hypnotics and Sedatives; Syndrome; Thalidomide | 1962 |
Thalidomide and limb deformities.
Topics: Congenital Abnormalities; Hypnotics and Sedatives; Thalidomide | 1962 |
[Congenital abnormalities and thalidomide].
Topics: Congenital Abnormalities; Hypnotics and Sedatives; Thalidomide | 1962 |
Association of thalidomide (Kevadon) with congenital anomalies.
Topics: Congenital Abnormalities; Hypnotics and Sedatives; Thalidomide | 1962 |
Thalidomide and congenital deformities.
Topics: Congenital Abnormalities; Humans; Hypnotics and Sedatives; Infant, Newborn; Infant, Newborn, Disease | 1962 |
Health of thalidomide victims and their progeny.
Topics: Abnormalities, Drug-Induced; Cause of Death; Child of Impaired Parents; Congenital Abnormalities; Fe | 2004 |
Living with thalidomide: health status and quality of life at 40 years.
Topics: Adult; Congenital Abnormalities; Disabled Persons; Female; Health Status; Humans; Hypnotics and Seda | 2007 |
Congenital malformations surveillance: two American systems.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Data Collection; Humans; Methods; Thalidomide | 1981 |
Representative and misrepresentative associations of birth defects in livebirths. Conditions under which relative risks greater than unity in livebirths necessarily imply relative risks greater than unity in all conceptuses.
Topics: Congenital Abnormalities; Embryo, Mammalian; Female; Fetal Death; Fetus; Humans; Infant, Newborn; Mo | 1993 |
Thalidomide: was the tragedy preventable?
Topics: Congenital Abnormalities; Ectromelia; Female; History, 16th Century; History, 18th Century; History, | 1998 |
Thalidomide disaster: old wine in new bottles?
Topics: Congenital Abnormalities; Disasters; Female; History, 20th Century; History, 21st Century; History, | 2001 |
Abstracts of papers presented at the eighteenth annual meeting of the Congenital Anomalies Research Association of Japan Yokohama, Japan July 13-14, 1978.
Topics: Animals; Chromosomes; Congenital Abnormalities; Congresses as Topic; Disease Models, Animal; Humans; | 1978 |
Experimental aspects and clinical implications.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Chick Embryo; Congenital Abn | 1979 |
Teratogenicity of therapeutic agents.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Abortion, Induced; Anesthetics; Anima | 1979 |
[Development of the extremities in the embryo].
Topics: Abnormalities, Drug-Induced; Animals; Arm; Congenital Abnormalities; Female; Humans; Infant, Newborn | 1978 |
[Epidemiology of congenital abnormalities].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Congenital Abnormalities; Epidemiologic Method | 1977 |
Letter: Congenital malformations and embryonic neuropathy.
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Humans; Neurons; Peripheral Nerves; | 1975 |
Clinical-epidemiologic assessment of pattern of birth defects associated with human teratogens: application to diabetic embryopathy.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Diabetes Mellitus, Type 1; Female; Georgia; H | 1989 |
Preventive surgery for congenital deformities of the hand.
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Female; Fetus; Genetic Engineering; | 1985 |
[Congenital abnormalities of rectum and anus. Diagnosis, physiology and therapy].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anal Canal; Anus, Imperforate; Congenital Abno | 1971 |
Teratology.
Topics: Abnormalities, Drug-Induced; Amphibians; Animals; Chick Embryo; Congenital Abnormalities; Embryo, Ma | 1969 |
Embryonic neuropathy. A hypothesis of neural chest injury as the pathogenesis of congenital malformations.
Topics: Abnormalities, Drug-Induced; Animals; Cell Movement; Central Nervous System; Child; Cleft Palate; Co | 1974 |
[Malformations in otorhinolaryngology. Genetic report].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Chromosome Aberrations; Chromosome Diso | 1972 |
Nicotinamide deficiency and thalidomide: potential teratogenic disturbances in Long-Evans rats.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Animal Feed; Animals; Birth Weight; Chlorproma | 1969 |
[Genetic analysis of skeletal diseases. Genetic report].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Bone and Bones; Bone Diseases; Child; Chromoso | 1973 |
Editorial: The pathogenesis of congenital malformations.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Female; Humans; Infant, Newborn; Pregnancy; P | 1974 |
Congenital malformations in nonhuman primates: spontaneous and experimentally induced.
Topics: Abnormalities, Drug-Induced; Aminopterin; Animals; Aspirin; Congenital Abnormalities; Female; Haplor | 1967 |
[Surgery of ear abnormalities (excluding the auricle)].
Topics: Abnormalities, Drug-Induced; Adrenergic beta-Antagonists; Anesthesia; Child; Congenital Abnormalitie | 1972 |
The dysplasias of the middle and the inner ear in different types of malformation.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Ear, Inner; Ear, Middle; Humans; Klippel-Feil | 1974 |
The missing umbilical artery. I. Prospective study based on a maternity unit.
Topics: Adult; Anencephaly; Birth Weight; Congenital Abnormalities; Female; Gestational Age; Humans; Hydroce | 1974 |
The significance of dermatoglyphics in medicine. A short survey and summary.
Topics: Abnormalities, Drug-Induced; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 13-15 | 1973 |
The marmoset as an animal model for teratological research.
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Disease Models, Animal; Female; Fetu | 1972 |
Sporadic malformations in laboratory animals and their influence on drug testing.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Laboratory; Aspirin; Bone and Bones; Congenital Abnor | 1972 |
Prospects and limitations of epidemiology in human teratology.
Topics: Abnormalities, Drug-Induced; Carcinogens; Chromosome Aberrations; Chromosome Disorders; Congenital A | 1973 |
[The teratogenic risk].
Topics: Abnormalities, Drug-Induced; Animals; Azathioprine; Busulfan; Carbutamide; Congenital Abnormalities; | 1968 |
Teratogeny in nonhuman primates, with notes on breeding procedures in Macaca mulatta.
Topics: Abnormalities, Drug-Induced; Androgens; Animals; Breeding; Chorionic Gonadotropin; Congenital Abnorm | 1969 |
Teratologists united.
Topics: Abnormalities, Drug-Induced; Animals; Central Nervous System; Congenital Abnormalities; Genetics, Me | 1971 |
[Malformation syndrome and urinary organs].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Child, Preschool; Chromosomes, Human, 1 | 1971 |
The thumb in the congenital malformation syndromes.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Acrocephalosyndactylia; Anemia, Aplastic; Arm; | 1971 |
[Synostosis of the radius and scaphoid bone in hypoplasia of the thumb].
Topics: Abnormalities, Drug-Induced; Carpal Bones; Child; Congenital Abnormalities; Humans; Male; Radiograph | 1971 |
Congenital aural atresia: anatomy and surgical management.
Topics: Abnormalities, Drug-Induced; Chromosome Aberrations; Congenital Abnormalities; Ear; Female; Follow-U | 1971 |
[Congenital ear abnormalities as a cause of deafness].
Topics: Abnormalities, Drug-Induced; Animals; Anura; Cats; Chick Embryo; Congenital Abnormalities; Cricetina | 1969 |
Congenital symmetric limb deformities.
Topics: Abnormalities, Drug-Induced; Arm; Black People; Congenital Abnormalities; Female; Humans; Infant, Ne | 1970 |
[The front line in research in experimental teratology].
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Female; Hominidae; Humans; Pregnancy | 1967 |
[Significance of exogenous influences for the development of human abnormalities].
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Female; Fetal Diseases; Humans; Infa | 1967 |
[Symposium on congential malformations. Introduction].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Congenital Abnormalities; Female; Humans; Infa | 1967 |
[The genesis of congenital malformations].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Antineoplastic Agents; Cell Division; C | 1967 |
A Swedish register of congenital malformations. Experience with continuous registration during 2 years with special reference to multiple malformations.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Congenital Abnormalities; Female; Fetal Death; | 1968 |
Genetical, social, and medical aspects of abortion.
Topics: Abnormalities, Drug-Induced; Abortion, Criminal; Abortion, Legal; Abortion, Therapeutic; Adolescent; | 1968 |
[The induction of monstrosities by chemical substances and their explanation].
Topics: Abnormalities, Drug-Induced; Animals; Arsenicals; Chick Embryo; Colchicine; Congenital Abnormalities | 1968 |
[Malformations].
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Embryology; Female; Fetal Diseases; | 1968 |
Dysmelia. A classification and a pattern of malformation in a group of congenital defects of the limbs.
Topics: Bone and Bones; Child; Congenital Abnormalities; Ectromelia; Femur; Humans; Humerus; Limb Deformitie | 1969 |
[Considerations on the occurrence of human abnormalities].
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Environment; Environmental Exposure; Female; | 1966 |
[Results of systematic studies of 96 dysmelia children].
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Ectromelia; Humans; Infant; Thalidomide | 1966 |