Page last updated: 2024-11-05

thalidomide and Abnormal Karyotype

thalidomide has been researched along with Abnormal Karyotype in 2 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Abnormal Karyotype: A variation from the normal set of chromosomes characteristic of a species.

Research Excerpts

ExcerptRelevanceReference
"Treatment benefit in multiple myeloma (MM) patients with high-risk cytogenetics remains suboptimal."1.62Subgroup analysis of ICARIA-MM study in relapsed/refractory multiple myeloma patients with high-risk cytogenetics. ( Alegre, A; Campana, F; Delimpasi, S; Facon, T; Harrison, SJ; Hulin, C; Inchauspé, M; Macé, S; Perrot, A; Richardson, P; Risse, ML; Simpson, D; Spencer, A; Sunami, K; van de Velde, H; Vlummens, P; Wang, MC; Yong, K, 2021)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Harrison, SJ1
Perrot, A1
Alegre, A1
Simpson, D1
Wang, MC1
Spencer, A1
Delimpasi, S1
Hulin, C1
Sunami, K1
Facon, T1
Vlummens, P1
Yong, K1
Campana, F1
Inchauspé, M1
Macé, S1
Risse, ML1
van de Velde, H1
Richardson, P1
Ortega, M1
Mallo, M1
Solé, F1
Sánchez-Morata, C1
López-Andreoni, L1
Martínez-Morgado, N1
Gironella, M1
Valcárcel, D1
Vallespí, T1

Other Studies

2 other studies available for thalidomide and Abnormal Karyotype

ArticleYear
Subgroup analysis of ICARIA-MM study in relapsed/refractory multiple myeloma patients with high-risk cytogenetics.
    British journal of haematology, 2021, Volume: 194, Issue:1

    Topics: Abnormal Karyotype; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplasti

2021
5q- syndrome and multiple myeloma diagnosed simultaneously and successful treated with lenalidomide.
    Leukemia research, 2013, Volume: 37, Issue:10

    Topics: Abnormal Karyotype; Aged; Anemia, Macrocytic; Antineoplastic Combined Chemotherapy Protocols; Chromo

2013