thalidomide has been researched along with AIDS Seroconversion in 13 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lenalidomide can be a good treatment option for AL amyloidosis in HIV-infected patients on antiretroviral therapy." | 5.46 | Lenalidomide as a treatment for relapsed AL amyloidosis in an HIV-positive patient. ( Cook, M; Denman, J; Manavi, K, 2017) |
| "Lenalidomide can be a good treatment option for AL amyloidosis in HIV-infected patients on antiretroviral therapy." | 1.46 | Lenalidomide as a treatment for relapsed AL amyloidosis in an HIV-positive patient. ( Cook, M; Denman, J; Manavi, K, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 8 (61.54) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Denman, J | 1 |
| Manavi, K | 1 |
| Cook, M | 1 |
| Agrawal, S | 1 |
| Deshpande, A | 1 |
| Sire, S | 1 |
| Fraisse, P | 1 |
| Rey, D | 1 |
| Jacquemin, C | 1 |
| Kempf, G | 1 |
| Partisani, M | 1 |
| Lang, JM | 1 |
| Naum, SM | 1 |
| Molloy, PJ | 1 |
| Kania, RJ | 1 |
| McGarr, J | 1 |
| Van Thiel, DH | 1 |
| Verberkmoes, A | 1 |
| Boer, K | 1 |
| Wertheim, PM | 1 |
| Bronkhorst, CM | 1 |
| Lange, JM | 1 |
| Ball, SC | 1 |
| Sepkowitz, KA | 1 |
| Jacobs, JL | 1 |
| Aseffa, A | 1 |
| Dietrich, MA | 1 |
| Shannon, EJ | 1 |
| Marriott, JB | 1 |
| Cookson, S | 1 |
| Carlin, E | 1 |
| Youle, M | 2 |
| Hawkins, DA | 1 |
| Nelson, M | 1 |
| Pearson, M | 1 |
| Vaughan, AN | 1 |
| Gazzard, B | 2 |
| Dalgleish, AG | 1 |
| Gori, A | 1 |
| Rossi, MC | 1 |
| Marchetti, G | 1 |
| Trabattoni, D | 1 |
| Molteni, C | 1 |
| Cogliati, M | 1 |
| Bandera, A | 1 |
| Clerici, M | 1 |
| Franzetti, F | 1 |
| Fieldston, E | 1 |
| Teo, SK | 1 |
| Chandula, RS | 1 |
| Harden, JL | 1 |
| Stirling, DI | 1 |
| Thomas, SD | 1 |
| Gorin, I | 1 |
| Vilette, B | 1 |
| Gehanno, P | 1 |
| Escande, JP | 1 |
| Clarbour, J | 1 |
| Farthing, C | 1 |
| Connolly, M | 1 |
| Hawkins, D | 1 |
| Staughton, R | 1 |
2 trials available for thalidomide and AIDS Seroconversion
| Article | Year |
|---|---|
A double-blind placebo-controlled phase II trial of thalidomide in asymptomatic HIV-positive patients: clinical tolerance and effect on activation markers and cytokines.
Topics: Adult; Anti-HIV Agents; Antigens, CD; beta 2-Microglobulin; Biomarkers; CD4 Antigens; CD8 Antigens; | 1997 |
Sensitive and rapid method for the determination of thalidomide in human plasma and semen using solid-phase extraction and liquid chromatography-tandem mass spectrometry.
Topics: Adult; Calibration; Chromatography, Liquid; Double-Blind Method; HIV Seropositivity; Humans; Male; M | 2002 |
11 other studies available for thalidomide and AIDS Seroconversion
| Article | Year |
|---|---|
Lenalidomide as a treatment for relapsed AL amyloidosis in an HIV-positive patient.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Dexamethasone; HI | 2017 |
A unique presentation of multiple myeloma in an HIV patient.
Topics: Aged; HIV; HIV Infections; HIV Seropositivity; Humans; Male; Multiple Myeloma; Radiography; Thalidom | 2013 |
[Efficacy of thalidomide in the treatment of esophageal ulcers in human immunodeficiency virus infection].
Topics: Acquired Immunodeficiency Syndrome; Adult; Esophageal Diseases; Fatal Outcome; HIV Infections; HIV S | 1995 |
Use of thalidomide in treatment and maintenance of idiopathic esophageal ulcers in HIV+ individuals.
Topics: Acquired Immunodeficiency Syndrome; Adult; Esophageal Diseases; Female; HIV Seropositivity; HIV-1; H | 1995 |
Thalidomide for genital ulcer in HIV-positive woman.
Topics: Adult; Female; Herpes Genitalis; HIV Seropositivity; HIV-1; Humans; Thalidomide; Ulcer; Vulvar Disea | 1996 |
Thalidomide for treatment of oral aphthous ulcers in patients with human immunodeficiency virus: case report and review.
Topics: Adult; Female; HIV Seropositivity; Humans; Stomatitis, Aphthous; Thalidomide | 1997 |
Effect of thalidomide on apoptosis of lymphocytes and neutrophils.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; CD3 Complex; Cell Line; HIV Seropositivity; Huma | 1997 |
Clinical and immunological benefit of adjuvant therapy with thalidomide in the treatment of tuberculosis disease.
Topics: Adult; Antitubercular Agents; CD4 Lymphocyte Count; Cytokines; Female; HIV Seronegativity; HIV Serop | 2000 |
AIDS, thalidomide and maternal-fetal rights in conflict.
Topics: Abortion, Eugenic; Acquired Immunodeficiency Syndrome; Coercion; Contraception; Drug-Related Side Ef | 1998 |
Thalidomide in hyperalgic pharyngeal ulceration of AIDS.
Topics: Acquired Immunodeficiency Syndrome; HIV Seropositivity; Homosexuality; Humans; Male; Middle Aged; Ph | 1990 |
Treatment of resistant aphthous ulceration with thalidomide in patients positive for HIV antibody.
Topics: Adult; Female; HIV Seropositivity; Humans; Male; Recurrence; Stomatitis, Aphthous; Thalidomide | 1989 |