Page last updated: 2024-11-05

thalidomide and 17p11.2 Monosomy

thalidomide has been researched along with 17p11.2 Monosomy in 4 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Biran, N1
Jagannath, S1
Chari, A1
Strati, P1
Keating, MJ1
O'Brien, SM1
Ferrajoli, A1
Burger, J1
Faderl, S1
Tambaro, FP1
Jain, N1
Wierda, WG1
Sun, C1
Wiestner, A1
Lee, J1
Smith, D1
Rabin, N1
Tobias, J1
Yong, K1

Reviews

2 reviews available for thalidomide and 17p11.2 Monosomy

ArticleYear
Risk stratification in multiple myeloma, part 2: the significance of genetic risk factors in the era of currently available therapies.
    Clinical advances in hematology & oncology : H&O, 2013, Volume: 11, Issue:9

    Topics: Angiogenesis Inhibitors; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair 13; Chr

2013
Prognosis and therapy of chronic lymphocytic leukemia and small lymphocytic lymphoma.
    Cancer treatment and research, 2015, Volume: 165

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Biomarkers, Tumor; Chromosome Deletion; Chromosomes,

2015

Other Studies

2 other studies available for thalidomide and 17p11.2 Monosomy

ArticleYear
Outcomes of first-line treatment for chronic lymphocytic leukemia with 17p deletion.
    Haematologica, 2014, Volume: 99, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chem

2014
17P deleted multiple myeloma presenting with intracranial disease: durable remission after tailored management.
    Hematological oncology, 2016, Volume: 34, Issue:3

    Topics: Autografts; Bortezomib; Brain Neoplasms; Chromosome Deletion; Chromosomes, Human, Pair 17; Consolida

2016