tezosentan has been researched along with Pulmonary Hypertension in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (47.37) | 29.6817 |
| 2010's | 10 (52.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, Z; Danser, AHJ; Duncker, DJ; Garcia-Alvarez, A; Ibanez, B; Merkus, D; Reiss, IKM; Stam, K; Uitterdijk, A; van Duin, RWB | 1 |
| Cromie, M; D'Armini, AM; Denault, AY; Lindberg, E; Michler, RE; Pearl, RG; Rao, V; Seitelberger, R; Tsui, SS | 1 |
| Badesch, DB; Barst, RJ; Benton, WW; Chakinala, MM; Farber, HW; Frantz, RP; Frost, AE; Hartline, BK; McLaughlin, VV; Miller, DP; Rosenberg, DM; Schilz, RJ | 1 |
| Fischer, V; Geiger, R; Kleinsasser, A; Loeckinger, A; Neu, N; Stein, JI; Treml, B | 1 |
| Oldner, A; Persson, BP; Rossi, P; Weitzberg, E | 1 |
| Couchot, E; de Lagausie, P; de Magnée, C; Guys, JM; Héry, G; Leprêtre, O; Paut, O; Rolland, PH; Stathopoulos, E | 1 |
| Andersson, A; Fenhammar, J; Frithiof, R; Hjelmqvist, H; Sollevi, A; Weitzberg, E | 1 |
| Albu, G; Beghetti, M; Fontao, F; Habre, W; Janosi, TZ; Petak, F; von Ungern-Sternberg, BS | 1 |
| Hedelin, P; Kylhammar, D; Rådegran, G | 1 |
| Fontoura, D; Leite-Moreira, AF; Lourenço, AP; Oliveira-Pinto, J; Roncon-Albuquerque, R; Vasques-Nóvoa, F | 1 |
| Hedelin, P; Kylhammar, D; Lundgren, J; Rådegran, G | 1 |
| Coralic, A; Dawson, KL; Fuentes, A | 1 |
| Minushkina, LO; Sidorenko, BA; Zateĭshchikov, DA | 1 |
| Fineman, JR; Fitzgerald, RK; Johengen, MJ; Oishi, P; Ovadia, B; Reinhartz, O; Ross, GA | 1 |
| Lorts, A; Shanley, TP | 1 |
| Fischer, V; Fratz, S; Geiger, R; Kleinsasser, A; Loeckinger, A; Maier, S; Navarro-Psiha, S; Neu, N; Pajk, W; Treml, B | 1 |
| Adatia, I; Coates, AL; Humpl, T; Katz, SL; Leung, K; Louca, E; Reyes, JT | 1 |
| Boomsma, F; Duncker, DJ; Houweling, B; Merkus, D; Sorop, O | 1 |
| Arner, A; Boels, PJ; Oldner, A; Persson, B; Rossi, P; Weitzberg, E | 1 |
2 review(s) available for tezosentan and Pulmonary Hypertension
| Article | Year |
|---|---|
A new epoprostenol formulation for the treatment of pulmonary arterial hypertension.
Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Storage; Epoprostenol; Exercise Tolerance; Familial Primary Pulmonary Hypertension; Humans; Hypertension, Pulmonary; Infusions, Intravenous; Medication Errors; Patient Education as Topic; Pyridines; Tetrazoles; Vasodilator Agents | 2012 |
[Endothelin receptor blockers--one more agent for the treatment of pulmonary hypertension].
Topics: Antihypertensive Agents; Bosentan; Carboxylic Acids; Clinical Trials as Topic; Endothelin Receptor Antagonists; Endothelium, Vascular; Humans; Hypertension, Pulmonary; Indans; Pyridines; Sulfonamides; Tetrazoles; Vasodilator Agents | 2003 |
1 trial(s) available for tezosentan and Pulmonary Hypertension
| Article | Year |
|---|---|
Tezosentan and right ventricular failure in patients with pulmonary hypertension undergoing cardiac surgery: the TACTICS trial.
Topics: Adult; Aged; Aged, 80 and over; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Double-Blind Method; Endpoint Determination; Female; Heart Failure; Humans; Hypertension, Pulmonary; Infusions, Intravenous; Male; Middle Aged; Pyridines; Tetrazoles; Vasodilator Agents; Ventricular Dysfunction, Right; Young Adult | 2013 |
16 other study(ies) available for tezosentan and Pulmonary Hypertension
| Article | Year |
|---|---|
Transition from post-capillary pulmonary hypertension to combined pre- and post-capillary pulmonary hypertension in swine: a key role for endothelin.
Topics: Animals; Down-Regulation; Endothelins; Endothelium, Vascular; Female; Hypertension, Pulmonary; Lung; Male; Microvessels; Pyridines; Swine; Tetrazoles; Vasodilator Agents; Ventricular Dysfunction, Left | 2019 |
Hospitalization and survival in patients using epoprostenol for injection in the PROSPECT observational study.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Female; Hospitalization; Humans; Hypertension, Pulmonary; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Pyridines; Tetrazoles; Vasodilator Agents | 2015 |
Intravenous tezosentan and vardenafil attenuate acute hypoxic pulmonary hypertension.
Topics: Animals; Dose-Response Relationship, Drug; Female; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Imidazoles; Injections, Intravenous; Male; Piperazines; Pulmonary Gas Exchange; Pyridines; Random Allocation; Sulfones; Swine; Tetrazoles; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents | 2008 |
Inhaled tezosentan reduces pulmonary hypertension in endotoxin-induced lung injury.
Topics: Administration, Inhalation; Animals; Endotoxins; Female; Hypertension, Pulmonary; Male; Pyridines; Random Allocation; Swine; Tetrazoles; Vasodilator Agents | 2009 |
Acute effect of a dual ETA-ETB receptor antagonist on pulmonary arterial vasculature in preterm lamb fetuses with surgically induced diaphragmatic hernia.
Topics: Animals; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Female; Fetus; Hemodynamics; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Pregnancy; Pulmonary Artery; Pyridines; Sheep; Statistics, Nonparametric; Tetrazoles | 2011 |
Endothelin-mediated gut microcirculatory dysfunction during porcine endotoxaemia.
Topics: Animals; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Endotoxemia; Female; Hypertension, Pulmonary; Ileum; Intestinal Mucosa; Isoxazoles; Microcirculation; Pyridines; Receptor, Endothelin A; Receptor, Endothelin B; Splanchnic Circulation; Sulfones; Sus scrofa; Tetrazoles; Vasodilator Agents | 2010 |
Prevention of bronchial hyperreactivity in a rat model of precapillary pulmonary hypertension.
Topics: Administration, Oral; Airway Resistance; Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelins; Hypertension, Pulmonary; Iloprost; Infusion Pumps, Implantable; Infusions, Parenteral; Lung; Lung Volume Measurements; Male; Nitric Oxide; Phosphodiesterase 5 Inhibitors; Piperazines; Prostaglandins I; Purines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Signal Transduction; Sildenafil Citrate; Sulfones; Tetrazoles; Time Factors; Vasoactive Intestinal Peptide; Vasodilator Agents | 2011 |
Dual endothelin receptor blockade with tezosentan markedly attenuates hypoxia-induced pulmonary vasoconstriction in a porcine model.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiac Output; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Female; Heart Rate; Hypertension, Pulmonary; Hypoxia; Infusions, Intravenous; Pulmonary Artery; Pyridines; Receptor, Endothelin A; Receptor, Endothelin B; Swine; Tetrazoles; Time Factors; Vascular Resistance; Vasoconstriction; Vasodilator Agents | 2012 |
Haemodynamic and neuroendocrine effects of tezosentan in chronic experimental pulmonary hypertension.
Topics: Animals; Chronic Disease; Cytokines; Dose-Response Relationship, Drug; Hemodynamics; Hypertension, Pulmonary; Male; Neurosecretion; Nitric Oxide; Prostaglandin-Endoperoxide Synthases; Pyridines; Random Allocation; Rats; Rats, Wistar; Tetrazoles; Vasodilator Agents; Ventricular Function, Right | 2012 |
sGC stimulation totally reverses hypoxia-induced pulmonary vasoconstriction alone and combined with dual endothelin-receptor blockade in a porcine model.
Topics: Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelin Receptor Antagonists; Enzyme Activators; Female; Guanylate Cyclase; Hypertension, Pulmonary; Hypoxia; Lung; Morpholines; Pyridines; Pyrimidines; Receptors, Endothelin; Swine; Tetrazoles; Vascular Resistance; Vasoconstriction; Vasodilator Agents | 2012 |
Tezosentan, a combined parenteral endothelin receptor antagonist, produces pulmonary vasodilation in lambs with acute and chronic pulmonary hypertension.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acute Disease; Animals; Animals, Newborn; Chronic Disease; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Hypertension, Pulmonary; Injections, Intra-Arterial; Pulmonary Circulation; Pyridines; Random Allocation; Sheep; Tetrazoles; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2004 |
Tezosentan, another selective selection for pulmonary hypertension, or not?
Topics: Animals; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Humans; Hypertension, Pulmonary; Pulmonary Circulation; Pyridines; Tetrazoles; Vasodilation; Vasodilator Agents | 2004 |
Tezosentan decreases pulmonary artery pressure and improves survival rate in an animal model of meconium aspiration.
Topics: Animals; Blood Pressure; Disease Models, Animal; Endothelin Receptor Antagonists; Humans; Hypertension, Pulmonary; Infant, Newborn; Meconium Aspiration Syndrome; Pulmonary Artery; Pulmonary Gas Exchange; Pyridines; Survival Analysis; Sus scrofa; Tetrazoles; Vascular Resistance | 2006 |
Nebulized therapies for childhood pulmonary hypertension: an in vitro model.
Topics: Adolescent; Antihypertensive Agents; Child; Epoprostenol; Humans; Hypertension, Pulmonary; Models, Theoretical; Nebulizers and Vaporizers; Piperazines; Purines; Pyridines; Sildenafil Citrate; Sulfones; Tetrazoles; Vasodilator Agents | 2006 |
Role of endothelin receptor activation in secondary pulmonary hypertension in awake swine after myocardial infarction.
Topics: Animals; Blood Pressure; Consciousness; Endothelin Receptor Antagonists; Endothelin-1; Female; Hemodynamics; Hypertension, Pulmonary; Male; Myocardial Infarction; Physical Conditioning, Animal; Pulmonary Circulation; Pyridines; Receptors, Endothelin; Rest; Swine; Tetrazoles; Vasoconstriction; Vasodilator Agents | 2006 |
Endotoxemic pulmonary hypertension is largely mediated by endothelin-induced venous constriction.
Topics: Animals; Ciprofloxacin; Endothelin-1; Female; Hypertension, Pulmonary; Lipopolysaccharides; Lung; Male; Pyridines; Respiratory Distress Syndrome; Sepsis; Swine; Tetrazoles; Vascular Resistance; Vasoconstriction; Vasodilator Agents | 2008 |