tetrodotoxin and Kidney-Failure--Chronic

tetrodotoxin has been researched along with Kidney-Failure--Chronic* in 2 studies

Other Studies

2 other study(ies) available for tetrodotoxin and Kidney-Failure--Chronic

ArticleYear
Serial electrophysiological changes in uraemic patients with tetrodotoxin intoxication.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2011, Volume: 122, Issue:11

    Topics: Adult; Animals; Disease Progression; Electrodiagnosis; Electrophysiology; Humans; Kidney Failure, Chronic; Male; Median Nerve; Middle Aged; Neural Conduction; Sodium Channel Blockers; Tetraodontiformes; Tetrodotoxin; Uremia

2011
[Case of tetrodotoxin intoxication in a uremic patient].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2007, Volume: 20, Issue:2

    Ingestion of certain types of puffer fish can result in severe and potentially lethal intoxication, referred to as tetrodotoxin (TTX) intoxication. It is well known that respiratory support plays a key role in the management of patients with TTX intoxication. We describe here the case of a 52-year-old uremic woman, who complained of numbness of the lips and weakness in the legs after ingestion of puffer fish (Lagocephalus wheeleri; called shirosaba-fugu in Japanese). While her symptoms were not severe and she did not require respiratory support, her condition did not improve after 2 days of hospitalization. Hemodialysis was therefore performed on hospital days 3, 4 and 5, and resulted in marked improvement of symptoms. We suggest that the patient's renal dysfunction caused an accumulation of TTX due to delayed excretion and thus modified the clinical course of TTX intoxication. Hemodialysis may be effective in the treatment of TTX intoxication. This is the first report of TTX intoxication in a uremic patient in Japan, and, importantly, the first report of intoxication with Lagocephalus wheeleri, which was previously considered to be a non-toxic species.

    Topics: Animals; Female; Humans; Kidney Failure, Chronic; Middle Aged; Renal Dialysis; Tetraodontiformes; Tetrodotoxin; Time Factors; Uremia

2007