tetrandrine has been researched along with Disease Models, Animal in 55 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (14.55) | 18.2507 |
| 2000's | 14 (25.45) | 29.6817 |
| 2010's | 22 (40.00) | 24.3611 |
| 2020's | 11 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Lin, J; Wei, X; Yin, J; Yu, J; Zhu, B; Zhu, C | 1 |
| Ding, Y; Tang, X; Wang, Y; Yu, D; Yu, J; Zhu, C | 1 |
| Cheung, KH; Ho, OK; Huang, AS; Iyaswamy, A; Kong, AH; Li, M; Liu, J; Song, J; Sreenivasmurthy, SG; Su, C; Tong, BC; Wu, AJ; Zhu, Z | 1 |
| Chen, R; He, S; Li, C; Liao, Y; Liu, H; Wang, J; Zou, Q | 1 |
| Ding, M; Feng, W; Fu, X; Lin, Y; Wang, Y; Wei, Y; Wu, M; Yao, J; Ying, X | 1 |
| Chen, X; Deng, X; Fu, T; Han, X; Liang, Y; Lu, M; Meng, Z; Su, W; Zhang, Q; Zhu, H | 1 |
| Du, L; Jin, Y; Li, R; Liu, Y; Ma, J; Pang, L; Yu, X; Zhang, L; Zhi, W; Zhu, L; Zhu, S; Zhuang, X; Zuo, H | 1 |
| Bao, X; Cai, X; Lu, L; Tang, L; Wang, Y; Wu, Z; Xu, Y | 1 |
| Du, Z; Gao, H; Hao, L; Huang, L; Wang, Z; Zhong, Y | 1 |
| Fu, Y; Jiang, C; Li, Z; Liu, J; Ren, D; Wang, H; Wang, L; Yuan, J; Zhong, X | 1 |
| Li, K; Li, W; Liu, T; Yu, M; Zhang, Z | 1 |
| Chen, Y; Li, W; Li, Y; Liu, T; Yu, M | 1 |
| Chen, YJ; Cheng, SY; Hwang, JJ; Leu, JD; Lin, WC; Lin, YH; Wang, WH | 1 |
| Gao, A; Li, S; Shi, J; Zhang, H; Zhu, K | 1 |
| Cao, Z; Deng, Z; Liu, J; Peng, L; Yao, H; Zhang, X | 1 |
| Rossan, RN; Van Dyke, K; Ye, Z | 1 |
| Bei, G; Chen, L; Cui, Z; Ge, T; Lv, Y; Qin, G; Zhou, J | 1 |
| Chen, HM; Gong, QJ; Huang, HS; Jin, WX; Li, XJ; Ruan, L | 1 |
| Cao, Y; Chen, Q; Fang, Y; Li, H; Qin, R; Shen, H; Xu, W | 1 |
| Duan, WL; Guo, GF; Huang, XH; Liang, XM; Zeng, ZL | 1 |
| Chen, Y; Hong, Z; Jiang, H; Wang, C; Xiao, X; Xu, G | 1 |
| Fu, P; Han, B; Wang, G; Ye, Y; Zhang, H | 1 |
| Chen, C; Dong, W; Lin, X; Lv, S; Tong, G; Wang, X; Yang, D; Yang, Y | 1 |
| Dai, Y; Lv, Q; Wei, ZF; Xia, YF; Zhu, XY | 1 |
| Chen, J; Chen, R; Feng, L; Jiang, Z; Li, X; Lou, J; Xia, H; Xiao, Y; Yin, X; Yu, M; Zhang, X; Zhu, L | 1 |
| He, TZ; Ji, Y; Jiang, J; Li, TM; Liu, M; Xiao, B; Xu, C | 1 |
| Cheng, LN; Gan, HT; Huang, XL; Shi, W; Xiang, JY; Zhang, DK | 1 |
| Chen, CJ; Li, K; Li, XJ; Li, YN; Li, YY; Lu, XY | 1 |
| Chen, W; Huang, JX; Meng, CS; Wang, ML; Zhang, X; Zhu, QH | 1 |
| Gao, A; Ho, HI; Wang, K; Zhang, G; Zhang, H | 1 |
| Chang, BF; Chen, Y; Chiu, KM; Chu, SH; Lin, TY; Tseng, SH; Wu, CC; Wu, JM | 1 |
| Bian, ZY; Li, H; Liu, C; Shen, DF; Tang, QZ; Wang, L; Yan, L; Zhang, Y; Zhu, LH | 1 |
| Huang, P; Li, H; Liu, J; Tang, Y; Wei, R; Xu, Y; Zhang, C; Zhang, SS | 1 |
| Cui, DJ; Gan, HT; He, FQ; Huang, XL; Li, TK; Qiu, BY; Xie, Q; Zhang, XH | 1 |
| Chang, CK; Du, Z; Huang, Z; Liu, W; Liu, X; Zhao, W | 1 |
| Cui, YL; Gao, S; Wang, QS; Yu, CQ; Zhang, Y | 1 |
| Li, XL; Li, YY; Yang, CX; Yao, H; Zhong, H; Zhu, L | 1 |
| Kobayashi, S; Kontani, H; Liu, YY; Tsutsumi, T | 1 |
| Leng, J; Li, QP; Peng, T; Rao, MR | 1 |
| Al-Humadi, NH; Hu, S; Ma, JK; Yin, XJ; Zhao, H | 1 |
| Lin, H; Liu, W; Wang, Y | 1 |
| Chen, ZX; Liu, WY; Wang, YG; Xiong, ZX; Xu, C | 1 |
| Jia, Q; Xin, HT; Xu, SH; Zhang, HN; Zhang, WD; Zhang, Y | 1 |
| Cheng, ZX; Liu, WY; Wang, YX; Xiong, ZX; Xu, C | 1 |
| Rao, MR; Xu, Y | 1 |
| Li, J; Wang, Y; Wu, S; Xiao, J; Zhang, S | 2 |
| Seow, WK; Thong, YH; Wong, CW | 1 |
| Dutt, J; Foster, CS; Hu, S; Zhao, T | 1 |
| Hong, CY; Huang, YT; Lin, HC; Liu, TB; Yang, MC | 1 |
| Chen, CF; Shen, YC; Sung, YJ | 1 |
| Kang, HC; Kim, JY; Ko, G; Nan, JX; Park, EJ; Park, PH; Sohn, DH | 1 |
| Feng, J; Hu, T; Hu, X; Jia, H; Jiang, X; Liu, W; Tang, Y | 1 |
| Kang, A; Liu, Z; San, S | 1 |
55 other study(ies) available for tetrandrine and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Tetrandrine may treat membranous glomerulopathy via P13K/Akt signaling pathway regulation: therapeutic mechanism validation using Heymann nephritis rat model.
Topics: Animals; Antioxidants; Benzylisoquinolines; Disease Models, Animal; Glomerulonephritis, Membranous; Male; Network Pharmacology; Phosphatidylinositol 3-Kinases; Protein Interaction Maps; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction | 2021 |
Tetrandrine alleviates podocyte injury via calcium-dependent calpain-1 signaling blockade.
Topics: Animals; Benzylisoquinolines; Calcium; Calcium Channel Blockers; Calpain; Cell Line; Disease Models, Animal; Doxorubicin; Male; Mice; Podocytes; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Signal Transduction | 2021 |
Tetrandrine ameliorates cognitive deficits and mitigates tau aggregation in cell and animal models of tauopathies.
Topics: Alzheimer Disease; Animals; Calcium; Cognition; Disease Models, Animal; Mice; Mice, Transgenic; tau Proteins; Tauopathies | 2022 |
Tetrandrine alleviates inflammation and neuron apoptosis in experimental traumatic brain injury by regulating the IRE1α/JNK/CHOP signal pathway.
Topics: Animals; Apoptosis; Benzylisoquinolines; Brain Injuries, Traumatic; Caspase 12; Caspase 3; Disease Models, Animal; Endoribonucleases; Inflammation; MAP Kinase Kinase 4; Mice; Neurons; NF-kappa B; Protein Serine-Threonine Kinases; Signal Transduction; TNF Receptor-Associated Factor 1; Transcription Factor CHOP; Tumor Necrosis Factor-alpha; Water | 2022 |
Tetrandrine Ameliorates Airway Remodeling of Chronic Asthma by Interfering TGF-
Topics: Airway Remodeling; Animals; Asthma; Benzylisoquinolines; Chronic Disease; Disease Models, Animal; Drug Evaluation, Preclinical; Heme Oxygenase-1; Immunosuppressive Agents; Male; Matrix Metalloproteinases; Membrane Proteins; Myocytes, Smooth Muscle; NF-E2-Related Factor 2; Oxidative Stress; Phytotherapy; Plant Extracts; Random Allocation; Rats, Wistar; Receptors, Leukotriene | 2019 |
Inhalation of Tetrandrine-hydroxypropyl-β-cyclodextrin Inclusion Complexes for Pulmonary Fibrosis Treatment.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Inhalation; Animals; Benzylisoquinolines; Disease Models, Animal; Lung; Male; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Solubility; Spectroscopy, Fourier Transform Infrared; Tumor Necrosis Factor-alpha | 2020 |
Intranasal tetrandrine temperature-sensitive in situ hydrogels for the treatment of microwave-induced brain injury.
Topics: Administration, Intranasal; Administration, Oral; Animals; Behavior, Animal; Benzylisoquinolines; Blood-Brain Barrier; Brain; Brain Injuries; Calcium Channel Blockers; Calcium Channels; Delayed-Action Preparations; Disease Models, Animal; Drug Compounding; Drug Liberation; Hydrogels; Male; Microwaves; Poloxamer; Rats, Wistar; Stimuli Responsive Polymers; Temperature; Tissue Distribution; Viscosity | 2020 |
Tetrandrine attenuates ischemia/reperfusion‑induced neuronal damage in the subacute phase.
Topics: Animals; Apoptosis; Autophagy; Benzylisoquinolines; Cerebral Cortex; Disease Models, Animal; Hippocampus; Humans; Male; Malondialdehyde; Neurons; Neuroprotective Agents; Oxidative Stress; Rats, Sprague-Dawley; Reperfusion Injury; Stroke | 2021 |
Combination Nanotherapeutics for Dry Eye Disease Treatment in a Rabbit Model.
Topics: Animals; Benzylisoquinolines; Cytokines; Disease Models, Animal; Drug Interactions; Dry Eye Syndromes; Epithelium, Corneal; Intraocular Pressure; Liposomes; Nanomedicine; Rabbits | 2021 |
Tetrandrine ameliorated Alzheimer's disease through suppressing microglial inflammatory activation and neurotoxicity in the 5XFAD mouse.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzylisoquinolines; Disease Models, Animal; Mice; Mice, Transgenic; Microglia; Peptide Fragments | 2021 |
The plant alkaloid tetrandrine inhibits metastasis via autophagy-dependent Wnt/β-catenin and metastatic tumor antigen 1 signaling in human liver cancer cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Autophagy; Benzylisoquinolines; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Epithelial-Mesenchymal Transition; Gene Expression; Gene Knockout Techniques; Histone Deacetylases; Humans; Liver Neoplasms; Male; Mice; Repressor Proteins; Trans-Activators; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2018 |
Combination therapy with protein kinase inhibitor H89 and Tetrandrine elicits enhanced synergistic antitumor efficacy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Benzylisoquinolines; Cell Line, Tumor; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Genes, myc; Genes, Reporter; Humans; Isoquinolines; Mice; Myeloid Cell Leukemia Sequence 1 Protein; Protein Kinase Inhibitors; Reactive Oxygen Species; Sulfonamides; Xenograft Model Antitumor Assays | 2018 |
Synergistic effects of tetrandrine combined with ionizing radiation on a murine colorectal carcinoma‑bearing mouse model.
Topics: Animals; Apoptosis; Benzylisoquinolines; Cell Proliferation; Chemoradiotherapy; Colorectal Neoplasms; Disease Models, Animal; Male; Mice; Mice, Inbred BALB C; Radiation-Sensitizing Agents; Radiation, Ionizing; Tumor Cells, Cultured | 2018 |
Tetrandrine enhances the antifungal activity of fluconazole in a murine model of disseminated candidiasis.
Topics: Animals; Antifungal Agents; Benzylisoquinolines; Candida albicans; Candidiasis; Disease Models, Animal; Drug Resistance, Fungal; Drug Synergism; Drugs, Chinese Herbal; Female; Fluconazole; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests | 2018 |
A novel controlled release tetrandrine-loaded PDLLA film: evaluation of drug release and anti-adhesion effects in vitro and in vivo.
Topics: Animals; Benzylisoquinolines; Chromatography, High Pressure Liquid; Collagen; Delayed-Action Preparations; Disease Models, Animal; Laminectomy; Polyesters; Rabbits; Random Allocation; Tissue Adhesions | 2020 |
Effective treatment with a tetrandrine/chloroquine combination for chloroquine-resistant falciparum malaria in Aotus monkeys.
Topics: Administration, Oral; Animals; Antimalarials; Aotus trivirgatus; Benzylisoquinolines; Chloroquine; Disease Models, Animal; Drug Resistance; Drug Therapy, Combination; Malaria, Falciparum; Parasitemia; Plasmodium falciparum; Recurrence; Treatment Outcome | 2013 |
Tetrandrine ameliorates cognitive impairment via inhibiting astrocyte-derived S100B activation in a rat model of chronic cerebral hypoperfusion.
Topics: Animals; Astrocytes; Benzylisoquinolines; Cerebrovascular Disorders; Chronic Disease; Cognition Disorders; Disease Models, Animal; Drugs, Chinese Herbal; Male; Maze Learning; Rats; S100 Calcium Binding Protein beta Subunit | 2013 |
Tetrandrine attenuated cerebral ischemia/reperfusion injury and induced differential proteomic changes in a MCAO mice model using 2-D DIGE.
Topics: Animals; Benzylisoquinolines; Brain Ischemia; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Endoplasmic Reticulum Chaperone BiP; Infarction, Middle Cerebral Artery; Male; Mass Spectrometry; Mice; Mice, Inbred BALB C; Proteomics; Reperfusion Injury | 2013 |
Tetrandrine induces mitochondria-mediated apoptosis in human gastric cancer BGC-823 cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Benzylisoquinolines; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Stomach Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Isotetrandrine protects against lipopolysaccharide-induced acute lung injury by suppression of mitogen-activated protein kinase and nuclear factor-kappa B.
Topics: Acute Lung Injury; Animals; Benzylisoquinolines; Bronchoalveolar Lavage Fluid; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Immunosuppressive Agents; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; NF-kappa B; Peroxidase; Pulmonary Edema | 2014 |
Beneficial effect of tetrandrine on refractory epilepsy via suppressing P-glycoprotein.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B; Benzylisoquinolines; Cell Line; Chemotherapy, Adjuvant; Disease Models, Animal; Drug Resistance, Multiple; Drug Resistant Epilepsy; Male; Rats; Rats, Sprague-Dawley | 2015 |
Protective effects of tetrandrine on brain cells in phenobarbital-dependent and -withdrawn rats.
Topics: Animals; bcl-2-Associated X Protein; Benzylisoquinolines; Brain; Disease Models, Animal; Drugs, Chinese Herbal; Female; Immunohistochemistry; Male; Neuroprotective Agents; Phenobarbital; Proto-Oncogene Proteins c-bcl-2; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders | 2015 |
Tetrandrine prevents monocrotaline-induced pulmonary arterial hypertension in rats through regulation of the protein expression of inducible nitric oxide synthase and cyclic guanosine monophosphate-dependent protein kinase type 1.
Topics: Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Antioxidants; Arterial Pressure; Benzylisoquinolines; Catalase; Cell Proliferation; Cyclic GMP-Dependent Protein Kinase Type I; Disease Models, Animal; Glutathione; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Malondialdehyde; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide Synthase Type II; Oxidative Stress; Pulmonary Artery; Rats, Sprague-Dawley; Signal Transduction; Superoxide Dismutase; Time Factors; Vascular Remodeling; Ventricular Remodeling | 2016 |
Tetrandrine inhibits migration and invasion of rheumatoid arthritis fibroblast-like synoviocytes through down-regulating the expressions of Rac1, Cdc42, and RhoA GTPases and activation of the PI3K/Akt and JNK signaling pathways.
Topics: Animals; Arthritis; Arthritis, Rheumatoid; Benzylisoquinolines; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Down-Regulation; Fibroblasts; Humans; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Phytotherapy; Plant Extracts; Plant Roots; Protein Serine-Threonine Kinases; rac1 GTP-Binding Protein; rhoA GTP-Binding Protein; Signal Transduction; Stephania; Synovial Membrane | 2015 |
[Study on the therapeutic effects of tetrandrine combined with N-acetylcysteine on experimental silicosis of rats].
Topics: Acetylcysteine; Animals; Benzylisoquinolines; Disease Models, Animal; Dust; Hydroxyproline; Interleukin-6; Lung; Malondialdehyde; Pulmonary Fibrosis; Quartz; Rats; Rats, Wistar; Silicon Dioxide; Silicosis; Tumor Necrosis Factor-alpha | 2015 |
[Effects of Tetrandrine Prenatal Intervention on Alveolar Epithelial Cells Type I Differentiation in Rat Model of Nitrofen-induced Congenital Diaphragmatic Hernia].
Topics: Alveolar Epithelial Cells; Animals; Benzylisoquinolines; Cell Differentiation; Disease Models, Animal; Female; Fetus; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley | 2016 |
Tetrandrine ameliorates dextran-sulfate-sodium-induced colitis in mice through inhibition of nuclear factor -kappaB activation.
Topics: Animals; Benzylisoquinolines; Colitis; Dextran Sulfate; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Immunosuppressive Agents; Interleukin-1beta; Mice; Mice, Inbred BALB C; NF-kappa B; Peroxidase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 2009 |
Intervention of pyrrolidine dithiocarbamate and tetrandrine on cellular calcium overload of pancreatic acinar cells induced by serum and ascitic fluid from rats with acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Anti-Inflammatory Agents; Ascitic Fluid; Benzylisoquinolines; Calcium; Calcium Channel Blockers; Cell Survival; Cells, Cultured; Deoxycholic Acid; Disease Models, Animal; NF-kappa B; Pancreas, Exocrine; Pancreatitis; Pyrrolidines; Rats; Rats, Sprague-Dawley; Thiocarbamates; Time Factors | 2009 |
[Experimental study on therapeutic efficacy of tetrandrine on lung injury induced by acute of paraquat poisoning].
Topics: Acute Disease; Animals; Benzylisoquinolines; Disease Models, Animal; Glutathione Peroxidase; Lung; Lung Injury; Male; Malondialdehyde; Paraquat; Rats; Rats, Wistar; Superoxide Dismutase | 2008 |
Synergistic anti-candidal activity of tetrandrine on ketoconazole: an experimental study.
Topics: Animals; Antifungal Agents; Benzylisoquinolines; Candida albicans; Candidiasis, Vulvovaginal; Colony Count, Microbial; Disease Models, Animal; Drug Resistance, Fungal; Drug Synergism; Drugs, Chinese Herbal; Female; Ketoconazole; Mice; Microbial Sensitivity Tests; Microbial Viability; Mucous Membrane; Phytotherapy; Random Allocation; Stephania tetrandra; Vagina; Vaginitis | 2010 |
Tetrandrine ameliorated reperfusion injury of small bowel transplantation.
Topics: Animals; Benzylisoquinolines; Cytokines; Disease Models, Animal; Drugs, Chinese Herbal; Enzyme-Linked Immunosorbent Assay; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-6; Intestine, Small; Male; Neutrophil Infiltration; Reperfusion Injury; Swine | 2009 |
Tetrandrine blocks cardiac hypertrophy by disrupting reactive oxygen species-dependent ERK1/2 signalling.
Topics: Administration, Oral; Animals; Animals, Newborn; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Benzylisoquinolines; Cardiomegaly; Cardiotonic Agents; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Fibrosis; Heart Failure; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; NF-kappa B; NFATC Transcription Factors; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Recovery of Function; Signal Transduction; Time Factors; Transfection; Ultrasonography; Ventricular Function, Left | 2010 |
Efficacy of tetrandrine on lowering intraocular pressure in animal model with ocular hypertension.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Benzylisoquinolines; Disease Models, Animal; Drugs, Chinese Herbal; Intraocular Pressure; Male; Ocular Hypertension; Rats; Rats, Sprague-Dawley; Timolol; Tonometry, Ocular; Treatment Outcome | 2011 |
Tetrandrine attenuates spatial memory impairment and hippocampal neuroinflammation via inhibiting NF-κB activation in a rat model of Alzheimer's disease induced by amyloid-β(1-42).
Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Animals; Benzylisoquinolines; Calcium Channel Blockers; Disease Models, Animal; Drug Interactions; Electrophoretic Mobility Shift Assay; Encephalitis; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Hippocampus; Interleukin-1beta; Male; Maze Learning; Memory Disorders; Neurons; NF-kappa B; Peptide Fragments; Phosphorus Isotopes; Protein Binding; Rats; Rats, Sprague-Dawley; Time Factors; Tumor Necrosis Factor-alpha | 2011 |
Inhibition effect of tetrandrine on haze formation after Epi-LASIK surgery in rabbits.
Topics: Animals; Benzylisoquinolines; Collagen Type III; Corneal Opacity; Corneal Stroma; Disease Models, Animal; Drugs, Chinese Herbal; Female; Fluorometholone; Immunoenzyme Techniques; Immunosuppressive Agents; Keratomileusis, Laser In Situ; Male; Ophthalmic Solutions; Postoperative Complications; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta2 | 2011 |
Tetrandrine exerts antidepressant-like effects in animal models: role of brain-derived neurotrophic factor.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzylisoquinolines; Brain-Derived Neurotrophic Factor; Depressive Disorder; Disease Models, Animal; Hindlimb Suspension; Hippocampus; Male; Mice; Mice, Inbred ICR; Motor Activity; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin; Stress, Psychological; Swimming | 2013 |
Effects of Tetrandrine and QYT on ICAM-1 and SOD gene expression in pancreas and liver of rats with acute pancreatitis.
Topics: Acute Disease; Alkaloids; Animals; Benzylisoquinolines; Disease Models, Animal; Drugs, Chinese Herbal; Female; Gene Expression Regulation; Immunosuppressive Agents; Intercellular Adhesion Molecule-1; Liver; Male; Pancreas; Pancreatitis; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxide Dismutase | 2003 |
Anti-hyperglycemic effect of fangchinoline isolated from Stephania tetrandra Radix in streptozotocin-diabetic mice.
Topics: Alkaloids; Animals; Benzylisoquinolines; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Fasting; Hyperglycemia; Insulin; Male; Mice; Mice, Inbred Strains; Stephania tetrandra; Structure-Activity Relationship | 2003 |
[Regression of vascular remodeling in renovascular hypertensive rats by tetrandrine and enalapril].
Topics: Alkaloids; Animals; Antihypertensive Agents; Aorta, Abdominal; Arterioles; Benzylisoquinolines; Blood Pressure; Disease Models, Animal; Drugs, Chinese Herbal; Enalapril; Hypertension, Renovascular; Kidney; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley | 2003 |
Silica-induced apoptosis in alveolar macrophages: evidence of in vivo thiol depletion and the activation of mitochondrial pathway.
Topics: Acetylcysteine; Alkaloids; Animals; Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulatory Proteins; Benzylisoquinolines; Caspase 3; Caspases; Cysteine; Cytochromes c; Disease Models, Animal; Glutathione; Inflammation Mediators; Macrophages, Alveolar; Male; Membrane Potentials; Microscopy, Confocal; Mitochondria; Oxidative Stress; Paclitaxel; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Silicon Dioxide; Sulfhydryl Compounds; Tumor Necrosis Factor-alpha | 2006 |
[Effect and significance of tetrandrine on epidermal growth factor and its receptor in the lung of congenital diaphragmatic hernia rat model].
Topics: Animals; Benzylisoquinolines; Disease Models, Animal; Epidermal Growth Factor; ErbB Receptors; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Pregnancy; Rats; Rats, Sprague-Dawley | 2006 |
[Effect of tetrandrine on endothelin expression in the lungs and clinical significance thereof: experiment with rat models with nitrofen-induced congenital diaphragmatic hernia].
Topics: Animals; Antineoplastic Agents, Phytogenic; Benzylisoquinolines; Disease Models, Animal; Endothelins; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Immunohistochemistry; Lung; Phenyl Ethers; Rats; Rats, Sprague-Dawley | 2007 |
[Effect of Chinese herbal drugs and tetrandrine on TGF-beta1 signaling pathway].
Topics: Animals; Benzylisoquinolines; Disease Models, Animal; Drugs, Chinese Herbal; Male; Rats; Rats, Wistar; Signal Transduction; Silicosis; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta1 | 2007 |
[Effect of tetrandrine on lung development: experiment of nitrofen-induced congenital diaphragmatic hernia fetal rat model].
Topics: Alkaloids; Animals; Animals, Newborn; Benzylisoquinolines; Disease Models, Animal; Drugs, Chinese Herbal; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Microscopy, Electron; Phenyl Ethers; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley | 2007 |
Effects of tetrandrine on left ventricle hypertrophy in deoxycorticosterone acetate-salt hypertensive rats.
Topics: Alkaloids; Animals; Antihypertensive Agents; Benzylisoquinolines; Binding, Competitive; Blood Pressure; Body Weight; Calcium; Desoxycorticosterone; Dihydropyridines; Disease Models, Animal; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Isradipine; Male; Mitochondria, Heart; Organ Size; Radioligand Assay; Random Allocation; Rats; Rats, Sprague-Dawley | 1995 |
Inhibitory effects of tetrandrine on bovine serum albumin-induced uveitis in rabbits.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigen-Antibody Complex; Aqueous Humor; Autoimmune Diseases; Benzylisoquinolines; Dexamethasone; Disease Models, Animal; Eye Proteins; Female; Lymphocyte Activation; Male; Rabbits; Serum Albumin, Bovine; T-Lymphocytes; Uveitis | 1993 |
Comparative effects of tetrandrine and berbamine on guineapig airway microvascular leakage induced by platelet-activating factor and other allergic mediators.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Benzylisoquinolines; Bradykinin; Capillary Permeability; Disease Models, Animal; Female; Guinea Pigs; Histamine; Hypersensitivity; Male; Platelet Activating Factor; Respiratory System; SRS-A | 1993 |
Tetrandrine potently inhibits herpes simplex virus type-1-induced keratitis in BALB/c mice.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Benzylisoquinolines; Blindness; Chlorocebus aethiops; Disease Models, Animal; Drugs, Chinese Herbal; Enzyme-Linked Immunosorbent Assay; Herpesvirus 1, Human; Keratitis, Herpetic; Male; Mice; Mice, Inbred BALB C; Vero Cells | 1997 |
Hemodynamic effects of chronic tetrandrine and propranolol administration on portal hypertensive rats.
Topics: Administration, Oral; Alkaloids; Analysis of Variance; Animals; Antihypertensive Agents; Benzylisoquinolines; Blood Pressure; Cardiac Output; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Heart Rate; Hemodynamics; Hypertension, Portal; Portal Vein; Propranolol; Rats; Rats, Sprague-Dawley; Vascular Resistance | 1997 |
Tetrandrine ameliorates ischaemia-reperfusion injury of rat myocardium through inhibition of neutrophil priming and activation.
Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzylisoquinolines; Blood Pressure; Cell Adhesion; Disease Models, Animal; Heart Rate; Macrophage-1 Antigen; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Neutrophil Activation; Neutrophil Infiltration; Neutrophils; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Up-Regulation | 1999 |
Effect of tetrandrine on experimental hepatic fibrosis induced by bile duct ligation and scission in rats.
Topics: Actins; Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzylisoquinolines; Bile Ducts; Cell Division; Cell Survival; Cells, Cultured; Cholestasis; Disease Models, Animal; Hepatocytes; Ligation; Liver Cirrhosis; Male; Muscle, Smooth; Rats; Rats, Sprague-Dawley | 2000 |
Effect of prenatal tetrandrine therapy on pulmonary vascular structural remodeling in the nitrofen-induced CDH rat model.
Topics: Alkaloids; Animals; Animals, Newborn; Benzylisoquinolines; Disease Models, Animal; Drugs, Chinese Herbal; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Male; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2000 |
Inhibitory effect of tetrandrine on lens proteins-induced ocular inflammation in rabbits.
Topics: Alkaloids; Animals; Anterior Chamber; Anti-Inflammatory Agents, Non-Steroidal; Benzylisoquinolines; Crystallins; Disease Models, Animal; Endophthalmitis; Eye Diseases; Female; Indomethacin; Injections; Intraocular Pressure; Iris; Leukocyte Count; Male; Neutrophils; Prostaglandins E; Rabbits | 1992 |
Effects of tetrandrine on lung-lipid contents of rats with experimental silicosis.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzylisoquinolines; Disease Models, Animal; Lipids; Lung; Macrophages, Alveolar; Male; Organ Size; Pulmonary Surfactants; Rats; Silicosis | 1992 |