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tetramisole and Sarcoma 180

tetramisole has been researched along with Sarcoma 180 in 3 studies

6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole : An imidazothiazole that is imidazo[2,1-b][1,3]thiazole in which the double bonds at the 2-3 and 5-6 positions have been reduced to single bonds and in which one of the hydrogens at position 6 is replaced by a phenyl group.
tetramisole : A racemate comprising equimolar amounts of levamisole and dexamisole.

Sarcoma 180: An experimental sarcoma of mice.

Research Excerpts

ExcerptRelevanceReference
"Tetramisole and its analogues are potent inhibitors of alkaline phosphatase, including isoenzymes of Sarcoma 180/TG which appear to be involved in the mechanism of resistance of this neoplastic cell line to the 6-thiopurines."7.66Synthesis and biological evaluation of tetramisole analogues as inhibitors of alkaline phosphatase of the 6-thiopurine-resistant tumor sarcoma 180/TG. ( Lee, MH; Li, C; Sartorelli, AC, 1979)
"Tetramisole and its analogues are potent inhibitors of alkaline phosphatase, including isoenzymes of Sarcoma 180/TG which appear to be involved in the mechanism of resistance of this neoplastic cell line to the 6-thiopurines."3.66Synthesis and biological evaluation of tetramisole analogues as inhibitors of alkaline phosphatase of the 6-thiopurine-resistant tumor sarcoma 180/TG. ( Lee, MH; Li, C; Sartorelli, AC, 1979)
"A series of tetramisole derivatives was synthesized and tested for inhibitory activity against alkaline phosphatase which was partially purified from a murine ascitic neoplasm resistant to 6-thiopurines (Sarcoma 180/TG)."3.65Tetramisole analogues as inhibitors of alkaline phosphatase, an enzyme involved in the resistance of neoplastic cells to 6-thiopurines. ( Agrawal, KC; Bhargava, KK; Cunningham, LS; Huang, Y; Lee, MH; Sartorelli, AC, 1977)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, C1
Lee, MH3
Sartorelli, AC3
Bhargava, KK1
Huang, Y1
Cunningham, LS1
Agrawal, KC2
Huang, YM1

Other Studies

3 other studies available for tetramisole and Sarcoma 180

ArticleYear
Synthesis and biological evaluation of tetramisole analogues as inhibitors of alkaline phosphatase of the 6-thiopurine-resistant tumor sarcoma 180/TG.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:9

    Topics: Alkaline Phosphatase; Animals; Drug Resistance; In Vitro Techniques; Mice; Purines; Sarcoma 180; Str

1979
Tetramisole analogues as inhibitors of alkaline phosphatase, an enzyme involved in the resistance of neoplastic cells to 6-thiopurines.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:4

    Topics: Alkaline Phosphatase; Animals; Cells, Cultured; Cyclization; Drug Interactions; Drug Resistance; Pur

1977
Inhibitors of alkaline phosphatase of Sarcoma 180/TG.
    Biochemical pharmacology, 1975, Jun-15, Volume: 24, Issue:11-12

    Topics: Alkaline Phosphatase; Animals; Beryllium; Dose-Response Relationship, Drug; Heterocyclic Compounds;

1975