tetramisole has been researched along with Down Syndrome in 2 studies
6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole : An imidazothiazole that is imidazo[2,1-b][1,3]thiazole in which the double bonds at the 2-3 and 5-6 positions have been reduced to single bonds and in which one of the hydrogens at position 6 is replaced by a phenyl group.
tetramisole : A racemate comprising equimolar amounts of levamisole and dexamisole.
Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
| Excerpt | Relevance | Reference |
|---|---|---|
| "By contrast, in pregnancies with trisomy 21 fetus, the proportion reached 60-80% of activity." | 1.31 | Kinetic comparison of tissue non-specific and placental human alkaline phosphatases expressed in baculovirus infected cells: application to screening for Down's syndrome. ( Biasini, GG; Brisson-Lougarre, AA; Denier, CC; Fournier, DD; Grozdea, JJ, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Denier, CJ | 1 |
| Vergnes, HA | 1 |
| Brisson-Lougarre, A | 1 |
| Grozdea, JG | 1 |
| Fournie, AE | 1 |
| Klaebe, AG | 1 |
| Perie, JJ | 1 |
| Denier, CC | 1 |
| Brisson-Lougarre, AA | 1 |
| Biasini, GG | 1 |
| Grozdea, JJ | 1 |
| Fournier, DD | 1 |
2 other studies available for tetramisole and Down Syndrome
| Article | Year |
|---|---|
Inhibition by sodium thiophosphate and L-p-bromotetramisole of neutrophil alkaline phosphatase in normal and trisomy 21 pregnancies.
Topics: Adult; Alkaline Phosphatase; Binding, Competitive; Bone and Bones; Case-Control Studies; Down Syndro | 1996 |
Kinetic comparison of tissue non-specific and placental human alkaline phosphatases expressed in baculovirus infected cells: application to screening for Down's syndrome.
Topics: Alkaline Phosphatase; Baculoviridae; Clinical Enzyme Tests; Down Syndrome; Enzyme Inhibitors; Enzyme | 2002 |