Page last updated: 2024-08-21

tetramethylpyrazine and Stroke

tetramethylpyrazine has been researched along with Stroke in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's5 (50.00)24.3611
2020's3 (30.00)2.80

Authors

AuthorsStudies
Jiang, J; Liu, W; Sun, Y; Wang, L; Wang, Y; Xu, C; Yu, P; Zhang, Z1
Du, J; Sun, Y; Wang, Y; Yu, P; Zhang, G; Zhang, Z; Zhong, H1
Chen, J; Dong, L; Dong, Y; Fu, X; Guo, T; Liu, M; Mao, Y; Qiao, C; Yang, Y; Zhang, J; Zhang, X; Zhao, Y1
Fu, B; Gao, G; Meng, S1
Lijuan, T; Ting, W; Xi, L; Xiaolu, C; Xiliang, Y; Xin, W; Yu, Z; Yuying, H; Zhenli, M1
Cao, H; Ge, L; Xu, M; Zhang, C; Zhang, J; Zhu, X1
Gong, X; He, X; Sun, M; Sun, Y; Wang, BO; Wang, M; Wang, X; Wang, Z; Wei, X; Yi, F; Zhang, Y; Zhou, Z1
Chen, C; Hao, Y; Hong, Y; Lei, H; Li, G; Tian, Y; Wang, P; Zhang, Y1
Chen, H; Jiang, J; Li, S; Wang, X; Wang, Y; Wu, J1
Liao, F1

Reviews

1 review(s) available for tetramethylpyrazine and Stroke

ArticleYear
Herbs of activating blood circulation to remove blood stasis.
    Clinical hemorheology and microcirculation, 2000, Volume: 23, Issue:2-4

    Topics: Aged; Animals; Anticoagulants; Blood Viscosity; Cardiovascular Agents; Coronary Disease; Drugs, Chinese Herbal; Fibrinolytic Agents; Hemodynamics; Hemorheology; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazines; Rats; Rats, Wistar; Stroke; Thrombosis

2000

Other Studies

9 other study(ies) available for tetramethylpyrazine and Stroke

ArticleYear
Antioxidative and thrombolytic TMP nitrone for treatment of ischemic stroke.
    Bioorganic & medicinal chemistry, 2008, Oct-01, Volume: 16, Issue:19

    Topics: Animals; Antioxidants; Brain Ischemia; Fibrinolytic Agents; Nitrogen Oxides; Pyrazines; Rats; Stroke; Thrombolytic Therapy

2008
Novel multi-functional nitrones for treatment of ischemic stroke.
    Bioorganic & medicinal chemistry, 2012, Jun-15, Volume: 20, Issue:12

    Topics: Animals; Dose-Response Relationship, Drug; Drug Design; Free Radical Scavengers; Male; Molecular Structure; Neurons; Neuroprotective Agents; Nitrogen Oxides; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Stroke; Structure-Activity Relationship

2012
Hybrid molecules of scutellarein and tertramethylpyrazine's active metabolites for ischemic stroke.
    Bioorganic & medicinal chemistry letters, 2019, 10-01, Volume: 29, Issue:19

    Topics: Animals; Apigenin; Brain Ischemia; Disease Models, Animal; Infarction, Middle Cerebral Artery; Neurons; Neuroprotective Agents; PC12 Cells; Pyrazines; Rats; Reperfusion Injury; Stroke

2019
A combination of tetramethylpyrazine hydrochloride and butylphthalide on serum S100B, CRP, Hcy levels and NIHSS score in patients with acute cerebral infarction: A retrospective study.
    Pakistan journal of pharmaceutical sciences, 2022, Volume: 35, Issue:3(Special)

    Topics: Acute Disease; Benzofurans; Brain Ischemia; Cerebral Infarction; Humans; Pyrazines; Retrospective Studies; S100 Calcium Binding Protein beta Subunit; Stroke

2022
Identification of ligustrazine-based analogs of piperlongumine as potential anti-ischemic stroke agents.
    Fitoterapia, 2023, Volume: 165

    Topics: Animals; Molecular Structure; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Stroke

2023
Dose-dependent effects of tetramethylpyrazine on the characteristics of human umbilical cord mesenchymal stem cells for stroke therapy.
    Neuroscience letters, 2020, 03-23, Volume: 722

    Topics: Cell Movement; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Pyrazines; Stroke; Umbilical Cord; Vasodilator Agents

2020
Therapeutic Potential of Novel Twin Compounds Containing Tetramethylpyrazine and Carnitine Substructures in Experimental Ischemic Stroke.
    Oxidative medicine and cellular longevity, 2017, Volume: 2017

    Topics: Animals; Brain Ischemia; Carnitine; Disease Models, Animal; Male; NADPH Oxidase 2; Neuroprotective Agents; Pyrazines; Rats; Rats, Sprague-Dawley; Stroke

2017
A Novel Ligustrazine Derivative T-VA Prevents Neurotoxicity in Differentiated PC12 Cells and Protects the Brain against Ischemia Injury in MCAO Rats.
    International journal of molecular sciences, 2015, 09-09, Volume: 16, Issue:9

    Topics: Animals; Behavior, Animal; Brain Ischemia; Ca(2+) Mg(2+)-ATPase; Cell Differentiation; Cell Survival; Cyclooxygenase 2; Disease Models, Animal; Immunohistochemistry; Neuroprotective Agents; NF-kappa B; PC12 Cells; Pyrazines; Rats; Stroke; Superoxide Dismutase; Toxicity Tests, Acute; Vascular Endothelial Growth Factor A

2015
Pharmacokinetic study of a novel stroke therapeutic, 2-[[(1,1-dimethylethyl)oxidoimino]methyl]-3,5,6-trimethylpyrazine, by a simple HPLC-UV method in rats.
    European journal of drug metabolism and pharmacokinetics, 2011, Volume: 36, Issue:2

    Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Half-Life; Indicators and Reagents; Pyrazines; Quality Control; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Stroke

2011