tetramethylpyrazine has been researched along with Spinal Cord Injuries in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 11 (61.11) | 24.3611 |
| 2020's | 6 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Li, W; Wang, C; Wang, P; Zeng, W | 1 |
| Li, J; Liu, Y; Luo, J; Qiao, R; Rao, Y | 1 |
| Bai, H; Deng, B; Fan, X; Jiang, S; Liu, G; Mu, X; Xu, L; Zhao, Y | 1 |
| Cui, XJ; Li, G; Shu, B; Sng, KS; Wang, YJ; Yao, M | 1 |
| Jiang, Q; Li, SJ; Qi, GD; Qi, W; Yang, ZX; Yu, ZJ | 1 |
| Du, X; Li, C; Li, J; Li, T; Lin, Y; Liu, Z; Wan, Y; Wei, J; Zhong, Z; Zhou, M | 1 |
| Bai, X; Du, X; Li, C; Li, J; Lin, Y; Liu, Z; Wan, Y; Wei, J; Zhong, Z; Zhou, M | 1 |
| Fan, Y; Wu, Y | 1 |
| Gao, T; Jiang, JD; Li, T; Shi, T; Wiesenfeld-Hallin, Z; Xu, XJ | 1 |
| Cheong, YJ; Kang, C; Moon, JY; Seong, JW; Shin, JW; Sohn, NW; Song, SH | 1 |
| Koushki, D; Latifi, S; Matin, M; Norouzi Javidan, A | 1 |
| Cao, Y; Hu, J; Lang, Y; Lu, H; Zhang, T | 1 |
| Cao, Y; Hu, J; Li, D; Lu, H; Wu, T | 1 |
| Cao, M; Cao, Y; Hu, JZ; Huang, JH; Lu, HB; Wang, G; Zeng, L | 1 |
| Cao, Y; Hu, JZ; Li, DZ; Lu, HB; Wang, XK; Wu, TD; Xu, DQ; Zhang, T | 1 |
| Hu, JZ; Li, XM; Lü, HB; Shen, ZX; Wang, XY; Xu, DQ | 1 |
| Hu, J; Li, J; Lu, H; Wang, S; Xiao, Z; Xu, D; Zhuo, X | 1 |
| Hu, JZ; Huang, JH; Li, JH; Li, XM; Lu, HB; Xiao, ZM | 1 |
2 review(s) available for tetramethylpyrazine and Spinal Cord Injuries
| Article | Year |
|---|---|
Effects of tetramethylpyrazine treatment in a rat model of spinal cord injury: A systematic review and meta-analysis.
Topics: Animals; Pyrazines; Quality of Life; Rats; Recovery of Function; Spinal Cord; Spinal Cord Injuries | 2023 |
Efficacy of some non-conventional herbal medications (sulforaphane, tanshinone IIA, and tetramethylpyrazine) in inducing neuroprotection in comparison with interleukin-10 after spinal cord injury: A meta-analysis.
Topics: Abietanes; Herbal Medicine; Humans; Interleukin-10; Isothiocyanates; Neuroprotective Agents; Pyrazines; Spinal Cord Injuries; Sulfoxides | 2015 |
16 other study(ies) available for tetramethylpyrazine and Spinal Cord Injuries
| Article | Year |
|---|---|
Tetramethylpyrazine improves the recovery of spinal cord injury via Akt/Nrf2/HO-1 pathway.
Topics: Animals; Apoptosis; Caspase 3; Chromones; Cytokines; Heme Oxygenase-1; Locomotion; Male; Morpholines; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-akt; Pyrazines; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord Injuries | 2016 |
Tetramethylpyrazine and Astragaloside IV have synergistic effects against spinal cord injury-induced neuropathic pain via the OIP5-AS1/miR-34a/Sirt1/NF-κB axis.
Topics: Animals; Apoptosis; MicroRNAs; Neuralgia; NF-kappa B; Rats; Rats, Sprague-Dawley; RNA, Long Noncoding; Sirtuin 1; Spinal Cord; Spinal Cord Injuries | 2023 |
[Experimental study on the repair of spinal cord injury by conducting hydrogel loaded with tetramethylpyrazine sustained-release microparticles].
Topics: Animals; Delayed-Action Preparations; Female; Hydrogels; Interleukin-10; NF-kappa B; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Tumor Necrosis Factor-alpha | 2023 |
[Neuroprotective effect of tetramethylpyrazine on mice after spinal cord injury].
Topics: Animals; Female; Interleukin-6; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Tumor Necrosis Factor-alpha | 2023 |
TAT-modified serum albumin nanoparticles for sustained-release of tetramethylpyrazine and improved targeting to spinal cord injury.
Topics: Animals; Cell Line; Delayed-Action Preparations; Drug Delivery Systems; Humans; Male; Mice; Nanoparticles; Pyrazines; Rats, Sprague-Dawley; Serum Albumin; Spinal Cord Injuries; tat Gene Products, Human Immunodeficiency Virus; Vasodilator Agents | 2021 |
TAT-modified tetramethylpyrazine-loaded nanoparticles for targeted treatment of spinal cord injury.
Topics: Animals; Nanoparticles; Neuroprotective Agents; Pyrazines; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries | 2021 |
Tetramethylpyrazine alleviates neural apoptosis in injured spinal cord via the downregulation of miR-214-3p.
Topics: Animals; Apoptosis; Blotting, Western; Disease Models, Animal; Down-Regulation; Flow Cytometry; HEK293 Cells; Humans; In Situ Nick-End Labeling; Male; MicroRNAs; Neurons; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Recovery of Function; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord Injuries; Up-Regulation | 2017 |
Sinomenine facilitates the efficacy of gabapentin or ligustrazine hydrochloride in animal models of neuropathic pain.
Topics: Analgesics; Animals; Disease Models, Animal; Drug Synergism; Gabapentin; Male; Mice; Mice, Inbred C57BL; Morphinans; Neuralgia; Peripheral Nerve Injuries; Pyrazines; Spinal Cord Injuries | 2019 |
Effects of tetramethylpyrazine on microglia activation in spinal cord compression injury of mice.
Topics: Animals; Cyclooxygenase 2; Drugs, Chinese Herbal; Inflammation Mediators; Interleukin-1beta; Ligusticum; Male; Mice; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; Neutrophil Infiltration; Nitric Oxide Synthase Type II; Phytotherapy; Pyrazines; Spinal Cord; Spinal Cord Compression; Spinal Cord Injuries; Tumor Necrosis Factor-alpha; Up-Regulation | 2013 |
The Neuroprotective Effect of Tetramethylpyrazine Against Contusive Spinal Cord Injury by Activating PGC-1α in Rats.
Topics: Animals; Locomotion; Male; Models, Biological; Neuroprotective Agents; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Pyrazines; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Transcription Factors | 2015 |
Micro-CT as a Tool to Investigate the Efficacy of Tetramethylpyrazine in a Rat Spinal Cord Injury Model.
Topics: Animals; Disease Models, Animal; Hindlimb; Male; Motor Activity; Neuroprotective Agents; Pyrazines; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries; X-Ray Microtomography | 2016 |
Tetramethylpyrazine enhances functional recovery after contusion spinal cord injury by modulation of MicroRNA-21, FasL, PDCD4 and PTEN expression.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Contusions; Disease Models, Animal; Fas Ligand Protein; Male; MicroRNAs; Neuroprotective Agents; PTEN Phosphohydrolase; Pyrazines; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord; Spinal Cord Injuries | 2016 |
Tetramethylpyrazine Facilitates Functional Recovery after Spinal Cord Injury by Inhibiting MMP2, MMP9, and Vascular Endothelial Cell Apoptosis.
Topics: Animals; Apoptosis; Disease Models, Animal; Endothelial Cells; Follow-Up Studies; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neurologic Examination; Platelet Aggregation Inhibitors; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries; Time Factors | 2017 |
[Tetramethylpyrazine accelerated spinal cord repair through regulation of caspase-3 and neurofilament protein expression: an acute spinal cord injury model in rats].
Topics: Animals; Caspase 3; Female; Male; Nerve Regeneration; Neurofilament Proteins; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 2008 |
[Effect of tetramethylpyrazine on the expression of macrophage migration inhibitory factor in acute spinal cord injury in rats].
Topics: Animals; Immunohistochemistry; Intramolecular Oxidoreductases; Macrophage Migration-Inhibitory Factors; Pyrazines; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 2012 |
Tetramethylpyrazine accelerates the function recovery of traumatic spinal cord in rat model by attenuating inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Count; Cytokines; Hindlimb; I-kappa B Proteins; Immunohistochemistry; Inflammation; Macrophage Migration-Inhibitory Factors; Male; Motor Activity; Neutrophil Infiltration; NF-kappa B; Pyrazines; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries | 2013 |