tetramethylpyrazine has been researched along with Pulmonary Hypertension in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (27.27) | 18.7374 |
| 1990's | 10 (45.45) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 2 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Bai, YZ; Cao, YQ; Dong, WP; Dong, Z; Liu, Y; Ma, XM; Wang, XW; Yang, B; Yang, DP; Yang, YC; Zeng, YY | 1 |
| Chen, Y; He, W; Hong, C; Liu, C; Lu, W; Ouyang, H; Wang, J; Wang, T; Yang, K | 1 |
| Black, SM; Chen, J; Chen, X; Chen, Y; Desai, AA; Duan, X; Garcia, JGN; He, W; Hong, C; Hou, C; Kuang, M; Li, M; Liao, J; Liu, C; Liu, S; Lu, W; Makino, A; Rischard, F; Tang, H; Vanderpool, RR; Wang, J; Wu, X; Yang, K; Yuan, JX; Zhang, J; Zhang, N; Zhang, Z; Zheng, Q; Zhong, N; Zou, G | 1 |
| Huang, LJ; Miu, CL; Wang, WT; Wu, CY; Zhang, CC; Zhao, MP; Zheng, MX | 1 |
| Feng, EZ; Huang, NX; Tian, ZX; Yang, SY; Yin, H; Zhang, Y | 1 |
| Chen, DZ; Huang, RJ; Liao, CX | 1 |
| Cao, W; Luo, W; Zeng, Z | 1 |
| Liu, SM; Tang, TQ | 1 |
| Cao, W; Guo, Z; Luo, W | 1 |
| Liu, B; Liu, J; Wu, K; Xu, Z; Yan, Y | 1 |
| Chui, S; Ding, W; Wang, B; Yang, B; Zhou, C | 1 |
| Cui, S; Ding, W; Wang, B; Yang, B; Zhou, C | 1 |
| Chen, X; Sun, R; Yan, Y | 1 |
| Chen, D; Huang, R; Liao, C | 1 |
| Barer, G; Bee, D; Emery, C; Oddoy, A | 1 |
| Chen, BH | 1 |
| Barer, GR; Cai, YN | 1 |
| Duan, SF; Peng, W | 1 |
| Yuan, XJ | 1 |
| Sun, RY | 1 |
| Cui, XX; Tang, TQ; Zhou, HX | 1 |
| Wang, DX; Wu, F; Zou, AP | 1 |
6 trial(s) available for tetramethylpyrazine and Pulmonary Hypertension
| Article | Year |
|---|---|
Efficacy and safety of tetramethylpyrazine phosphate on pulmonary hypertension: study protocol for a randomized controlled study.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Arterial Pressure; China; Exercise Tolerance; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Pyrazines; Randomized Controlled Trials as Topic; Recovery of Function; Single-Blind Method; Time Factors; Treatment Outcome; Vasodilator Agents; Young Adult | 2019 |
[The effects and mechanisms of ligustrazine injection on pulmonary arterial hypertension in COPD patients].
Topics: Humans; Hypercapnia; Hypertension, Pulmonary; Pulmonary Disease, Chronic Obstructive; Pyrazines | 2016 |
Plasma endothelin-1 and nitric oxide correlate with ligustrazine alleviation of pulmonary artery hypertension in patients of chronic cor pulmonale from high altitude plateau during acute exacerbation.
Topics: Altitude; Blood Gas Analysis; Chronic Disease; Endothelin-1; Humans; Hypertension, Pulmonary; Nitric Oxide; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pyrazines; Respiration | 2014 |
[Effect of tetramethylpyrazine on endothelin, von Willebrand factor and thromboxane A2 during cardiopulmonary bypass in patients of congenital heart disease with pulmonary hypertension].
Topics: Adolescent; Adult; Calcium Channel Blockers; Cardiopulmonary Bypass; Child; Child, Preschool; Endothelins; Female; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Male; Pyrazines; Thromboxane B2; von Willebrand Factor | 2003 |
[Clinical and experimental studies of feiyaning in treating pulmonary arterial hypertension in cor pulmonale].
Topics: Adult; Aged; Aged, 80 and over; Animals; Cardiac Output; Cross-Over Studies; Drugs, Chinese Herbal; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Pulmonary Heart Disease; Pyrazines; Random Allocation; Rats; Rats, Wistar; Vascular Resistance | 1994 |
[Effects in tetramethylpyrazine on TXA2 and PGI2 by cardio-pulmonary bypass in congenital heart diseases with pulmonary hypertension patients].
Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Cardiopulmonary Bypass; Child; Child, Preschool; Female; Heart Septal Defects, Atrial; Heart Septal Defects, Ventricular; Humans; Hypertension, Pulmonary; Male; Pyrazines; Thromboxane B2; Vasodilator Agents | 1998 |
16 other study(ies) available for tetramethylpyrazine and Pulmonary Hypertension
| Article | Year |
|---|---|
Tetramethylpyrazine Improves Monocrotaline-Induced Pulmonary Hypertension through the ROS/iNOS/PKG-1 Axis.
Topics: Animals; Hypertension, Pulmonary; Monocrotaline; Nitric Oxide Synthase Type II; Protein Kinases; Pyrazines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2022 |
Tetramethylpyrazine: A promising drug for the treatment of pulmonary hypertension.
Topics: Animals; Cell Proliferation; Disease Models, Animal; Humans; Hypertension, Pulmonary; Monocrotaline; Myocytes, Smooth Muscle; Pharmaceutical Preparations; Pulmonary Artery; Pyrazines; Rats; Rats, Sprague-Dawley | 2020 |
[The effect of acute pulmonary alveolar hypoxia on canine plasma endothelin-1 levels].
Topics: Animals; Calcium Channel Blockers; Dogs; Endothelins; Female; Hypertension, Pulmonary; Hypoxia; Male; Pyrazines | 1994 |
[Effects of ligustrazine and nitroglycerine on acute hypoxic pulmonary hypertension in anesthetized dogs].
Topics: Acute Disease; Animals; Blood Pressure; Calcium Channel Blockers; Dogs; Female; Hypertension, Pulmonary; Hypoxia; Male; Methylene Blue; Nitroglycerin; Pyrazines; Vascular Resistance | 1994 |
[Changes of collagen distribution in extrapulmonary arteries of hypoxia-induced pulmonary hypertensive rat].
Topics: Altitude Sickness; Animals; Anti-Inflammatory Agents, Non-Steroidal; Collagen; Drugs, Chinese Herbal; Fibrinolytic Agents; Hypertension, Pulmonary; Male; Pulmonary Artery; Pyrazines; Rats; Rats, Wistar | 1995 |
[Image morphological quantitative analysis of pathological changes of intra-acinar arteries in experimental pulmonary artery hypertension and outcomes of treatment].
Topics: Alkaloids; Allyl Compounds; Animals; Antihypertensive Agents; Benzylisoquinolines; Disulfides; Hypertension, Pulmonary; Image Processing, Computer-Assisted; Pulmonary Artery; Pyrazines; Rats; Rats, Wistar | 1996 |
[Observation of relationship between function and structure of experimental pulmonary artery hypertension in rats and inhibitory effect of garlicin and other herbal medicines].
Topics: Alkaloids; Allyl Compounds; Animals; Antihypertensive Agents; Benzylisoquinolines; Blood Pressure; Disulfides; Hypertension, Pulmonary; Male; Monocrotaline; Pulmonary Artery; Pyrazines; Random Allocation; Rats; Rats, Wistar; Vasodilator Agents | 1996 |
[Effect of 764-3 and ligustrazine on collagen content of extrapulmonary arteries during chronic hypoxia].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Collagen; Drugs, Chinese Herbal; Hydroxyproline; Hypertension, Pulmonary; Hypoxia; Male; Pulmonary Artery; Pyrazines; Rats; Rats, Wistar | 1996 |
Effects of ligustrazine on the pressure/flow relationship in isolated perfused rat lungs.
Topics: Animals; Arginine; Blood Flow Velocity; Blood Pressure; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Hypoxia; Male; Nitric Oxide; Pulmonary Artery; Pulmonary Circulation; Pyrazines; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilator Agents | 1991 |
[Effect of penicillamine and tetramethyl pyrazine on the hypoxic pulmonary hypertension in rats].
Topics: Animals; Female; Hypertension, Pulmonary; Hypoxia; Male; Penicillamine; Pyrazines; Rats; Rats, Inbred Strains; Vasodilator Agents | 1990 |
Effect of ligustrazine on pulmonary vascular changes induced by chronic hypoxia in rats.
Topics: Animals; Blood Pressure; Chronic Disease; Hypertension, Pulmonary; Hypoxia; Pulmonary Artery; Pyrazines; Rats; Rats, Inbred Strains; Vasodilator Agents | 1989 |
The acute effects of ligustrazini on hemodynamics and right cardiac function in pulmonary arterial hypertension secondary to chronic obstructive pulmonary disease.
Topics: Adult; Aged; Female; Heart; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Male; Middle Aged; Pyrazines; Vasodilator Agents | 1989 |
[Inhibitory effect of ligustrazine on acute and chronic pulmonary hypertension in rats].
Topics: Animals; Calcium Channel Blockers; Hemodynamics; Hyperbaric Oxygenation; Hypertension, Pulmonary; Hypoxia; Pyrazines; Rats; Rats, Inbred Strains | 1988 |
[Dilative effect of injection of radix Angelicae, Salvia miltiorrhiza and ligustrazin on the pulmonary vessels in rats].
Topics: Animals; Blood Pressure; Drug Combinations; Drugs, Chinese Herbal; Hypertension, Pulmonary; Male; Phenanthrolines; Plant Extracts; Pulmonary Artery; Pyrazines; Rats; Rats, Inbred Strains; Salvia miltiorrhiza; Vasodilator Agents | 1988 |
[Therapeutic effects of ligustrazine on pulmonary hypertension. Report on 38 assessments with right heart catheterization and blood gas analysis].
Topics: Adult; Aged; Carbon Dioxide; Cardiac Catheterization; Female; Humans; Hypertension, Pulmonary; Injections, Intra-Arterial; Male; Middle Aged; Oxygen; Pulmonary Artery; Pyrazines | 1988 |
Effect of tetramethylpyrazine on acute and chronic hypoxic pulmonary hypertension of the rat.
Topics: Animals; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Male; Pyrazines; Rats; Rats, Inbred Strains; Vasodilator Agents | 1986 |