Page last updated: 2024-08-21

tetramethylpyrazine and Lung Neoplasms

tetramethylpyrazine has been researched along with Lung Neoplasms in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's2 (18.18)29.6817
2010's5 (45.45)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Ai, Y; Ding, K; Huang, Z; Kang, F; Lai, Y; Li, J; Peng, S; Ren, C; Tian, J; Zhang, Y; Zhu, B1
Li, X; Lin, D; Lin, J; Lin, Z; Wang, P; Xu, J; Zhang, D; Zhou, C1
Ding, R; Fan, P; Guo, M; Wang, G; Xu, D; Xu, X; Zhang, E; Zheng, Y1
Bai, Y; Gao, J; Hu, D; Liang, C; Liu, Y; Wang, F; Wu, J; Zhou, J1
Huang, HH; Liu, FB; Ruan, Z; Su, YJ; Wang, J; Zheng, J1
Chen, S; Fu, Y; Jia, Y; Jiao, S; Wang, Z; Zang, A1
Liang, Y; Lin, Y; Liu, Y; Yin, W; Zhang, J1
Chen, L; Gao, M; Lei, N; Lu, Y; Wang, AY; Wu, JM; Xu, B; Zhang, CB; Zhang, LJ; Zhang, WW; Zheng, SZ1
Pan, XJ; Xiao, W; Yang, ZH; Zheng, CY; Zhou, SY; Zhu, MX1
Feng, J; Sun, R; Tian, Z; Wei, H; Xiao, W; Xu, X; Zhen, C1
Chen, SX; Wang, LX; Xing, LL1

Trials

1 trial(s) available for tetramethylpyrazine and Lung Neoplasms

ArticleYear
[Effects of tetramethylpyrazine on platelet functions of advanced cases of lung carcinoma].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1997, Volume: 17, Issue:9

    Topics: 6-Ketoprostaglandin F1 alpha; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Female; Humans; Lung Neoplasms; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazines; Thromboxane B2

1997

Other Studies

10 other study(ies) available for tetramethylpyrazine and Lung Neoplasms

ArticleYear
Discovery of New Monocarbonyl Ligustrazine-Curcumin Hybrids for Intervention of Drug-Sensitive and Drug-Resistant Lung Cancer.
    Journal of medicinal chemistry, 2016, Mar-10, Volume: 59, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Curcumin; Dose-Response Relationship, Drug; Drug Discovery; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Lung Neoplasms; Mice; Molecular Structure; Neoplasms, Experimental; Pyrazines; Reactive Oxygen Species; Structure-Activity Relationship; Thioredoxin-Disulfide Reductase

2016
Tetramethylpyrazine-Rhein Derivative inhibits the migration of canine inflammatory mammary carcinoma cells by mitochondrial damage-mediated apoptosis and cadherins downregulation.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 162

    Topics: Animals; Apoptosis; Cadherins; Carcinoma; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dogs; Down-Regulation; Lung Neoplasms

2023
Synthesis and in-vitro study of a novel ligustrazine diselenide as a potential chemotherapy drug for lung adenocarcinoma.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 165

    Topics: Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt

2023
Development of novel celastrol-ligustrazine hybrids as potent peroxiredoxin 1 inhibitors against lung cancer.
    European journal of medicinal chemistry, 2023, Nov-05, Volume: 259

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Pentacyclic Triterpenes; Peroxiredoxins; Reactive Oxygen Species; Triterpenes

2023
Tetramethylpyrazine (TMPZ) triggers S-phase arrest and mitochondria-dependent apoptosis in lung cancer cells.
    Neoplasma, 2018, Mar-14, Volume: 65, Issue:3

    Topics: Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Pyrazines

2018
Tetramethylpyrazine inhibits tumor growth of lung cancer through disrupting angiogenesis via BMP/Smad/Id-1 signaling.
    International journal of oncology, 2016, Volume: 48, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Bone Morphogenetic Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Differentiation Protein 1; Injections, Intraperitoneal; Lung Neoplasms; Mice; Pyrazines; Signal Transduction; Smad Proteins; Time Factors; Xenograft Model Antitumor Assays

2016
IRE1α-TRAF2-ASK1 pathway is involved in CSTMP-induced apoptosis and ER stress in human non-small cell lung cancer A549 cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 82

    Topics: A549 Cells; Apoptosis; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Cycle; Cell Survival; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Endoribonucleases; Humans; Lung Neoplasms; MAP Kinase Kinase Kinase 5; Mitochondria; Protein Binding; Protein Serine-Threonine Kinases; Pyrazines; RNA, Small Interfering; Signal Transduction; TNF Receptor-Associated Factor 2

2016
Ligustrazine inhibits B16F10 melanoma metastasis and suppresses angiogenesis induced by Vascular Endothelial Growth Factor.
    Biochemical and biophysical research communications, 2009, Aug-21, Volume: 386, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Cell Movement; Cell Proliferation; Female; Fibroblasts; Humans; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Microvessels; Neovascularization, Pathologic; Pyrazines; Rats; Vascular Endothelial Growth Factor A

2009
Inhibition of cyclooxygenase-2 by tetramethylpyrazine and its effects on A549 cell invasion and metastasis.
    International journal of oncology, 2012, Volume: 40, Issue:6

    Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclooxygenase 2 Inhibitors; Dinoprostone; Female; Humans; Immunoglobulin G; Lung Neoplasms; Matrix Metalloproteinase 2; Melphalan; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Pyrazines; Xenograft Model Antitumor Assays

2012
Type two cytokines predominance of human lung cancer and its reverse by traditional Chinese medicine TTMP.
    Cellular & molecular immunology, 2004, Volume: 1, Issue:1

    Topics: Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Drugs, Chinese Herbal; Female; Gene Expression; Humans; Ligusticum; Lung Neoplasms; Male; Medicine, Chinese Traditional; Mice; Middle Aged; Pyrazines

2004