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tetramethylpyrazine and Injury, Myocardial Reperfusion

tetramethylpyrazine has been researched along with Injury, Myocardial Reperfusion in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (14.29)18.2507
2000's7 (50.00)29.6817
2010's5 (35.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ding, JD; Ma, GS; Sheng, ZL; Wang, X; Zuo, PF; Zuo, Z1
Gao, Q; Huang, W; Su, M; Yang, Y; Zeng, Z; Zhu, B1
Jiao, BM; Li, ZL; Qian, HJ; Su, L; Zheng, JS1
Fang, ZX; Hao, ML; Ni, SR; Song, ZJ; Wang, FY; Wang, WT; Xie, KJ1
He, Z; Liu, H; Liu, J; Liu, X; Zeng, Z; Zhou, W1
Cheng, Y; Gong, JB; Jiang, SS; Lv, L; Xu, J1
Cheng, Y; Gong, J; Jiang, S; Lv, L; Meng, Q; Xu, J1
Deng, HW; Deng, PY; Hu, CP; Li, YJ; Zhou, Y1
Chen, SY; Cheng, PY; Hsiao, G; Hwang, HR; Lee, YM1
Davey, AK; Evans, AM; Li, Y; Wang, J; Xu, D; Zhang, S1
Chen, HP; He, M; Huang, QR; Liu, D; Zeng, GH1
Fu, CJ; Zhang, JF; Zhao, GS1
Lin, LN; Wang, WT; Xu, ZJ1
Shao, W; Zhang, W; Zhou, S1

Trials

2 trial(s) available for tetramethylpyrazine and Injury, Myocardial Reperfusion

ArticleYear
[Clinical study on ligustrazine in treating myocardial ischemia and reperfusion injury].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1997, Volume: 17, Issue:5

    Topics: Adolescent; Adult; Female; Free Radical Scavengers; Glutathione Peroxidase; Heart Septal Defects; Heart Valve Diseases; Humans; Male; Malondialdehyde; Myocardial Reperfusion Injury; Pyrazines; Rheumatic Heart Disease; Superoxide Dismutase

1997
[Clinical study of Astragalus injection plus ligustrazine in protecting myocardial ischemia reperfusion injury].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2000, Volume: 20, Issue:7

    Topics: Adolescent; Adult; Astragalus Plant; Astragalus propinquus; Cardiopulmonary Bypass; Drugs, Chinese Herbal; Female; Heart Septal Defects, Ventricular; Heart Valve Prosthesis Implantation; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Reperfusion Injury; Pyrazines; Rheumatic Heart Disease

2000

Other Studies

12 other study(ies) available for tetramethylpyrazine and Injury, Myocardial Reperfusion

ArticleYear
Tetramethylprazine attenuates myocardial ischemia/reperfusion injury through modulation of autophagy.
    Life sciences, 2019, Dec-15, Volume: 239

    Topics: Animals; Apoptosis; Autophagy; Cardiotonic Agents; Cell Survival; Chromones; Creatine Kinase; L-Lactate Dehydrogenase; Male; Morpholines; Myocardial Reperfusion Injury; Myocytes, Cardiac; Primary Cell Culture; Protein Kinase Inhibitors; Pyrazines; Rats; Rats, Sprague-Dawley

2019
Effect of Salvia miltiorrhiza and ligustrazine injection on myocardial ischemia/reperfusion and hypoxia/reoxygenation injury.
    Molecular medicine reports, 2016, Volume: 14, Issue:5

    Topics: Animals; bcl-2-Associated X Protein; Caspase 3; Coronary Occlusion; Coronary Vessels; Creatine Kinase; Gene Expression Regulation; Humans; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Oncogene Protein v-akt; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Rats; Reperfusion Injury; Salvia miltiorrhiza; Signal Transduction

2016
[The influence of JNK inhibitor on hemodynamics after ischemia/reperfusion injury to the heart in rats].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2008, Volume: 20, Issue:12

    Topics: Animals; Anthracenes; Disease Models, Animal; Hemodynamics; JNK Mitogen-Activated Protein Kinases; Male; Myocardial Reperfusion Injury; Protein Kinase Inhibitors; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley

2008
[Effect of ligustrazine and L-arginine on function of mitochondria in myocardium after ischemia/reperfusion injury of myocardium in rabbits].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2007, Volume: 23, Issue:2

    Topics: Animals; Arginine; Calcium; Malondialdehyde; Mitochondria, Heart; Myocardial Reperfusion Injury; Pyrazines; Rabbits; Superoxide Dismutase

2007
Pharmacokinetics of ligustrazine ethosome patch in rats and anti-myocardial ischemia and anti-ischemic reperfusion injury effect.
    International journal of nanomedicine, 2011, Volume: 6

    Topics: Animals; Area Under Curve; Blood Viscosity; Chi-Square Distribution; Fibrinolytic Agents; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Pyrazines; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Tissue Distribution; Transdermal Patch

2011
Protective effect of ligustrazine against myocardial ischaemia reperfusion in rats: the role of endothelial nitric oxide synthase.
    Clinical and experimental pharmacology & physiology, 2012, Volume: 39, Issue:1

    Topics: Animals; Apoptosis; Cardiotonic Agents; Caspase 3; Enzyme Inhibitors; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction

2012
Ligustrazine attenuates myocardial ischemia reperfusion injury in rats by activating the phosphatidylinositol 3-kinase/Akt pathway.
    Annals of clinical and laboratory science, 2012,Spring, Volume: 42, Issue:2

    Topics: Animals; Creatine Kinase, MB Form; Enzyme Activation; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Pyrazines; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxide Dismutase

2012
The protective effects of ligustrazine on ischemia-reperfusion and DPPH free radical-induced myocardial injury in isolated rat hearts.
    Planta medica, 2004, Volume: 70, Issue:9

    Topics: Animals; Biphenyl Compounds; Cardiotonic Agents; Ligusticum; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Phytotherapy; Picrates; Plant Extracts; Pyrazines; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha

2004
Tetramethylpyrazine induces heme oxygenase-1 expression and attenuates myocardial ischemia/reperfusion injury in rats.
    Journal of biomedical science, 2006, Volume: 13, Issue:5

    Topics: Animals; Arrhythmias, Cardiac; Chemotaxis; Fibrinolytic Agents; Gene Expression; Heme Oxygenase-1; Humans; Ligusticum; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Neutrophils; Plant Extracts; Pyrazines; Rats; Rats, Sprague-Dawley; Respiratory Burst; Superoxides

2006
The cardioprotective effect of isosteviol on rats with heart ischemia-reperfusion injury.
    Life sciences, 2007, Jan-02, Volume: 80, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Cardiotonic Agents; Decanoic Acids; Disease Models, Animal; Diterpenes, Kaurane; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Heart Rate; Hydroxy Acids; Injections, Intravenous; Myocardial Infarction; Myocardial Reperfusion Injury; Pyrazines; Rats; Rats, Sprague-Dawley; Tachycardia, Ventricular; Ventricular Fibrillation

2007
Delayed protection of tetramethylpyrazine on neonatal rat cardiomyocytes subjected to anoxia-reoxygenation injury.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 100, Issue:6

    Topics: Alkaloids; Animals; Benzophenanthridines; Cell Survival; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glutathione Peroxidase; HSP70 Heat-Shock Proteins; In Vitro Techniques; L-Lactate Dehydrogenase; Malondialdehyde; Myocardial Reperfusion Injury; Myocytes, Cardiac; Protein Kinase C; Pyrazines; Rats; Superoxide Dismutase; Vasodilator Agents

2007
[Effect of ligustrazine on isolated myocardial ischemic reperfusion injury in rats].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1993, Volume: 13, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Female; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Myocardial Reperfusion Injury; Pyrazines; Rats; Rats, Sprague-Dawley; Thromboxane B2

1993