tetramethylpyrazine has been researched along with Heart Disease, Ischemic in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shan, L; Sun, Y; Wang, Y; Xu, C; Yu, P; Zhang, G; Zhang, X; Zhang, Z | 1 |
| Deng, H; Hu, H; Luo, J; Shan, L; Wang, Y; Yu, P; Zhang, G; Zhang, X; Zhang, Z | 1 |
| Chen, B; Huang, DD; Huang, HH; Li, DG; Yang, Q; Yuan, CL; Zhang, LM | 1 |
| Ando, K; Cao, X; Enkhsaikhan, A; Izumi-Nakaseko, H; Kishie, T; Nakamura, Y; Sugiyama, A; Wada, T; Xu, B; Zhu, B | 1 |
| He, Z; Liu, H; Liu, J; Liu, X; Zeng, Z; Zhou, W | 1 |
| Cheng, Y; Gong, JB; Jiang, SS; Lv, L; Xu, J | 1 |
| Deng, HW; Deng, PY; Hu, CP; Li, YJ; Zhou, Y | 1 |
| Chen, SY; Cheng, PY; Hsiao, G; Hwang, HR; Lee, YM | 1 |
| Jing, Z; Pu, Z; Zeng, Z; Zhu, W; Zuo, W | 1 |
| Gasser, R; Grisold, M; Köppel, H | 1 |
| Feng, J; Tang, S; Wu, G | 1 |
11 other study(ies) available for tetramethylpyrazine and Heart Disease, Ischemic
| Article | Year |
|---|---|
Synthesis and Biological Evaluation of Danshensu and Tetramethylpyrazine Conjugates as Cardioprotective Agents.
Topics: Animals; Apoptosis; Cardiotonic Agents; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Lactates; Male; Molecular Structure; Myocardial Ischemia; Oxidative Stress; Pyrazines; Rats; Rats, Sprague-Dawley; Solubility; Structure-Activity Relationship | 2017 |
A Novel Danshensu-Tetramethylpyrazine Conjugate DT-010 Provides Cardioprotection through the PGC-1α/Nrf2/HO-1 Pathway.
Topics: Animals; Cell Line; Cell Survival; Free Radicals; Heme Oxygenase-1; Iodoacetic Acid; Lactates; Ligusticum; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium; Myocytes, Cardiac; NF-E2-Related Factor 2; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phytotherapy; Plant Extracts; Pyrazines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Salvia miltiorrhiza; tert-Butylhydroperoxide; Up-Regulation | 2017 |
Tetramethylpyrazine exerts a protective effect against injury from acute myocardial ischemia by regulating the PI3K/Akt/GSK-3β signaling pathway.
Topics: Animals; Cytokines; Glycogen Synthase Kinase 3 beta; Inflammation; Isoproterenol; Male; Myocardial Ischemia; Phosphatidylinositol 3-Kinases; Protective Agents; Proto-Oncogene Proteins c-akt; Pyrazines; Rats; Rats, Sprague-Dawley; Signal Transduction | 2019 |
Assessment of the Anti-anginal Effect of Tetramethylpyrazine Using Vasopressin-Induced Angina Model Rats.
Topics: Animals; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Heart Rate; Male; Myocardial Ischemia; Pyrazines; Rats; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins | 2016 |
Pharmacokinetics of ligustrazine ethosome patch in rats and anti-myocardial ischemia and anti-ischemic reperfusion injury effect.
Topics: Animals; Area Under Curve; Blood Viscosity; Chi-Square Distribution; Fibrinolytic Agents; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Pyrazines; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Tissue Distribution; Transdermal Patch | 2011 |
Protective effect of ligustrazine against myocardial ischaemia reperfusion in rats: the role of endothelial nitric oxide synthase.
Topics: Animals; Apoptosis; Cardiotonic Agents; Caspase 3; Enzyme Inhibitors; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction | 2012 |
The protective effects of ligustrazine on ischemia-reperfusion and DPPH free radical-induced myocardial injury in isolated rat hearts.
Topics: Animals; Biphenyl Compounds; Cardiotonic Agents; Ligusticum; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Phytotherapy; Picrates; Plant Extracts; Pyrazines; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2004 |
Tetramethylpyrazine induces heme oxygenase-1 expression and attenuates myocardial ischemia/reperfusion injury in rats.
Topics: Animals; Arrhythmias, Cardiac; Chemotaxis; Fibrinolytic Agents; Gene Expression; Heme Oxygenase-1; Humans; Ligusticum; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Neutrophils; Plant Extracts; Pyrazines; Rats; Rats, Sprague-Dawley; Respiratory Burst; Superoxides | 2006 |
[Effect of tetramethyl pyrazine on coronary vasoconstriction induced by endothelin-1 in dogs].
Topics: Animals; Coronary Angiography; Coronary Vessels; Dogs; Endothelin-1; Heart Rate; Male; Myocardial Ischemia; Pyrazines; Vasoconstriction; Vasodilator Agents | 1996 |
First description of the effect of a non-sulfonylurea compound, tetramethylpyrazine, on coronary response to desoxyglucose-induced ischemia.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Deoxyglucose; Flavoring Agents; Guinea Pigs; Myocardial Ischemia; Organ Culture Techniques; Perfusion; Potassium Channels; Pyrazines; Sweetening Agents; Vasodilation | 1998 |
The effects of tetramethylpyrazine on the incidence of arrhythmias and the release of PGI2 and TXA2 in the ischemic rat heart.
Topics: Animals; Arrhythmias, Cardiac; Epoprostenol; Heart; Male; Myocardial Ischemia; Pyrazines; Rats; Rats, Sprague-Dawley; Thromboxane A2 | 1999 |