tetramethylpyrazine and Alzheimer Disease
tetramethylpyrazine has been researched along with Alzheimer Disease in 11 studies
Research
Studies (11)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (9.09) | 29.6817 |
2010's | 6 (54.55) | 24.3611 |
2020's | 4 (36.36) | 2.80 |
Authors
Authors | Studies |
---|---|
Cai, Q; Huang, G; Li, W; Li, Z; Liu, W; Ma, G; Meng, X; Wang, S; Zhang, Y | 1 |
Chen, H; Deng, C; Meng, S; Meng, Z | 1 |
Huang, S; Huang, Z; Liu, T; Weng, G; Zhou, B | 1 |
Jiang, SJ; Liu, J; Qin, XH; Wang, J; Wang, LX; Zhang, Q; Zhu, L | 1 |
Li, W; Li, X; Liang, X; Lu, F; Wei, K; Yao, Y; Zhang, J; Zhang, Q | 1 |
Feng, X; Hong, G; Li, G; Li, X; Liu, T; Mao, L; Xu, Z; Zhang, Y | 1 |
Amjad, MW; Bukhari, SNA; Hussain, MA; Leng, J; Qin, HL; Raja, MAG; Wang, M | 1 |
Cai, W; Chen, HY; Cui, W; Han, YF; Long, C; Sun, YW; Tan, GL; Tsim, KW; Wang, JZ; Wang, YQ; Xu, DP; Yu, P; Zhang, GX; Zhang, ZJ | 1 |
Cong, W; Liu, Q; Luo, G; Shi, J; Wang, Y | 1 |
Luo, G; Shi, J; Wang, Y | 1 |
Cai, J; Cui, X; Wang, SZ; Zhang, C; Zuo, PP | 1 |
Other Studies
11 other study(ies) available for tetramethylpyrazine and Alzheimer Disease
Article | Year |
---|---|
Increasing brain glucose metabolism by ligustrazine piperazine ameliorates cognitive deficits through PPARγ-dependent enhancement of mitophagy in APP/PS1 mice.
Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cognition; Disease Models, Animal; Fluorodeoxyglucose F18; Glucose; Luciferases; Mice; Mice, Transgenic; Mitophagy; Piperazine; PPAR gamma; Presenilin-1; Protein Kinases; Pyrazines; Rats; Sequestosome-1 Protein; Ubiquitin-Protein Ligases | 2022 |
Tetramethylpyrazine ameliorates systemic streptozotocin-induced Alzheimer-like pathology.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Hippocampus; Mice; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Streptozocin | 2023 |
Tetramethylpyrazine Improves Cognitive Function of Alzheimer's Disease Mice by Regulating SSTR4 Ubiquitination.
Topics: Alzheimer Disease; Animals; Cognition; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pyrazines; Rats; Receptors, Somatostatin; Tumor Cells, Cultured; Ubiquitination | 2021 |
Ligustrazine Attenuates Hyperhomocysteinemia-induced Alzheimer-like Pathologies in Rats.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Disease Models, Animal; Hippocampus; Humans; Hyperhomocysteinemia; Memory Disorders; Neurons; Neuroprotective Agents; Phosphorylation; Pyrazines; Rats; Rats, Sprague-Dawley | 2021 |
Tetramethylpyrazine reverses intracerebroventricular streptozotocin-induced memory deficits by inhibiting GSK-3β.
Topics: Alzheimer Disease; Animals; Glycogen Synthase Kinase 3; Hippocampus; Injections, Intraventricular; Learning; Male; Memory; Memory Disorders; Neurons; Neuroprotective Agents; Pyrazines; Rats, Wistar; Streptozocin | 2017 |
Synthesis and activity towards Alzheimer's disease in vitro: Tacrine, phenolic acid and ligustrazine hybrids.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Cholinesterase Inhibitors; Humans; Hydroxybenzoates; Models, Molecular; PC12 Cells; Pyrazines; Rats; Tacrine | 2018 |
Synthesis and biological evaluation of new tetramethylpyrazine-based chalcone derivatives as potential anti-Alzheimer agents.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Cell Survival; Chalcones; Drug Design; Humans; Inhibitory Concentration 50; Monoamine Oxidase; PC12 Cells; Protective Agents; Pyrazines; Rats; Structure-Activity Relationship | 2018 |
A Potent Multi-functional Neuroprotective Derivative of Tetramethylpyrazine.
Topics: Alzheimer Disease; Animals; Antioxidants; Cells, Cultured; Hydrazones; Mice; Neurons; Neuroprotective Agents; PC12 Cells; Pyrazines; Rats; Rats, Sprague-Dawley | 2015 |
Microemulsion-based patch for transdermal delivery of huperzine A and ligustrazine phosphate in treatment of Alzheimer's disease.
Topics: Administration, Cutaneous; Alkaloids; Alzheimer Disease; Animals; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Therapy, Combination; Emulsions; Male; Neuroprotective Agents; Pyrazines; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Skin Absorption; Time Factors; Transdermal Patch; Vasodilator Agents | 2012 |
Ligustrazine phosphate ethosomes for treatment of Alzheimer's disease, in vitro and in animal model studies.
Topics: Acrylic Resins; Administration, Cutaneous; Alzheimer Disease; Amnesia; Animals; Antioxidants; Behavior, Animal; Brain; Chemistry, Pharmaceutical; Disease Models, Animal; Drug Carriers; Escape Reaction; Ethanol; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Memory; Mice; Mice, Inbred ICR; Mice, Nude; Microscopy, Confocal; Permeability; Phosphatidylcholines; Pyrazines; Rats; Rats, Sprague-Dawley; Reaction Time; Scopolamine; Skin; Skin Absorption; Superoxide Dismutase; Technology, Pharmaceutical; Time Factors | 2012 |
Protective effect of tetramethylpyrazine on learning and memory function in D-galactose-lesioned mice.
Topics: Alzheimer Disease; Animals; Galactose; Hippocampus; Male; Maze Learning; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Pyrazines; Receptors, Muscarinic | 2004 |