tetrahydropapaveroline has been researched along with Parkinson Disease in 10 studies
*Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Esch, T; Králíčková, M; Kream, RM; Kuzelova, H; Mantione, KJ; Ptacek, R; Stefano, GB | 1 |
| Collins, MA | 1 |
| Blarzino, C; Cini, C; Coccia, R; De Marco, F; Foppoli, C; Marcante, ML; Perluigi, M | 1 |
| Kim, MN; Kim, YM; Lee, JJ; Lee, MK | 1 |
| Hermida-Ameijeiras, A; Méndez-Alvarez, E; Sánchez-Iglesias, S; Sánchez-Sellero, I; Sanmartín-Suárez, C; Soto-Otero, R | 1 |
| Cashaw, JL | 1 |
| Burke, W; Coscia, CJ; Jamroz, G; Lasala, JM; McFarlane, J; Mitchell, J; O'Toole, MM; Wilson, ML | 1 |
| Akane, A; Fukushima, S; Kobayashi, S; Matsubara, K; Shiono, H | 1 |
| Mizuno, Y; Suzuki, K; Yoshida, M | 1 |
| Cashaw, JL; Geraghty, CA | 1 |
1 review(s) available for tetrahydropapaveroline and Parkinson Disease
| Article | Year |
|---|---|
Parkinson's disease, L-DOPA, and endogenous morphine: a revisit.
Topics: Animals; Codeine; Humans; Levodopa; Morphine; Parkinson Disease; Tetrahydropapaveroline | 2012 |
9 other study(ies) available for tetrahydropapaveroline and Parkinson Disease
| Article | Year |
|---|---|
Tetrahydropapaveroline in Parkinson's disease and alcoholism: a look back in honor of Merton Sandler.
Topics: Alcoholism; Animals; History, 20th Century; History, 21st Century; Humans; Parkinson Disease; Tetrahydropapaveroline | 2004 |
Ectopic deposition of melanin pigments as detoxifying mechanism: a paradigm for basal nuclei pigmentation.
Topics: Antioxidants; Blotting, Northern; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Cytoplasm; Formamides; Glutathione Peroxidase; HeLa Cells; Humans; Keratinocytes; Melanins; Models, Chemical; Parkinson Disease; Peroxidases; RNA; RNA, Messenger; Superoxide Dismutase; Tetrahydropapaveroline; Time Factors; Transfection; Ultraviolet Rays | 2004 |
Inhibition of dopamine biosynthesis by tetrahydropapaveroline.
Topics: Adrenal Medulla; Animals; Antioxidants; Cattle; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Levodopa; Nerve Degeneration; Neurons; Oxidative Stress; Parkinson Disease; PC12 Cells; Rats; Tetrahydropapaveroline; Tyrosine 3-Monooxygenase; Up-Regulation | 2005 |
Study on the ability of 1,2,3,4-tetrahydropapaveroline to cause oxidative stress: Mechanisms and potential implications in relation to parkinson's disease.
Topics: Animals; Brain; In Vitro Techniques; Lipid Peroxidation; Male; Mitochondria; Oxidation-Reduction; Oxidative Stress; Parkinson Disease; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sulfhydryl Compounds; Tetrahydropapaveroline | 2006 |
Determination of tetrahydropapaveroline in the urine of parkinsonian patients receiving L-dopa-carbidopa (Sinemet) therapy by high-performance liquid chromatography.
Topics: Adsorption; Aluminum Oxide; Antiparkinson Agents; Carbidopa; Cation Exchange Resins; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Drug Combinations; Electrochemistry; Humans; Levodopa; Parkinson Disease; Resins, Synthetic; Silanes; Tetrahydropapaveroline | 1993 |
Occurrence of a new class of tetrahydroisoquinoline alkaloids in L-dopa-treated parkinsonian patients.
Topics: Animals; Biotransformation; Brain; Carbidopa; Catechols; Humans; Levodopa; Mice; Papaverine; Parkinson Disease; Rats; Tetrahydropapaveroline | 1977 |
Increased urinary morphine, codeine and tetrahydropapaveroline in parkinsonian patient undergoing L-3,4-dihydroxyphenylalanine therapy: a possible biosynthetic pathway of morphine from L-3,4-dihydroxyphenylalanine in humans.
Topics: Adult; Alcohol Drinking; Codeine; Humans; Levodopa; Male; Morphine; Pain; Parkinson Disease; Tetrahydropapaveroline | 1992 |
Inhibition of mitochondrial respiration by 1,2,3,4-tetrahydroisoquinoline-like endogenous alkaloids in mouse brain.
Topics: Adenosine Triphosphate; Animals; Brain; Glutamates; Glutamic Acid; Humans; Isoquinolines; Malates; Male; Mice; Mice, Inbred C57BL; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Oxygen Consumption; Parkinson Disease; Pyruvates; Pyruvic Acid; Quinone Reductases; Tetrahydroisoquinolines; Tetrahydropapaveroline | 1990 |
Method for the identification of tetrahydropapaveroline using the Pictet-Spengler condensation reaction and high-performance liquid chromatography.
Topics: Animals; Brain Chemistry; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Papaverine; Parkinson Disease; Rats; Tetrahydropapaveroline | 1989 |