tetrahydrocortisol has been researched along with Obesity in 7 studies
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the oral 11 beta-hydroxysteroid dehydrogenase-1 (11β-HSD1) inhibitor BI 187004 (NCT02150824), as monotherapy and in combination with metformin, versus placebo in patients with type 2 diabetes mellitus (T2DM) affected by overweight or obesity." | 5.69 | Safety, tolerability, pharmacodynamics and pharmacokinetics following once-daily doses of BI 187004, an inhibitor of 11 beta-hydroxysteroid dehydrogenase-1, over 28 days in patients with type 2 diabetes mellitus and overweight or obesity. ( Bianzano, S; Heise, T; Nordaby, M; Peil, B; Plum-Mörschel, L, 2023) |
| "After weight loss, excretion of cortisol and cortisone metabolites decreased." | 3.79 | Cortisol metabolism after weight loss: associations with 11 β-HSD type 1 and markers of obesity in women. ( Axelson, M; Lönn, L; Rask, E; Simonyte, K, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Bianzano, S | 2 |
| Nordaby, M | 2 |
| Plum-Mörschel, L | 2 |
| Peil, B | 2 |
| Heise, T | 2 |
| Rask, E | 1 |
| Simonyte, K | 1 |
| Lönn, L | 1 |
| Axelson, M | 1 |
| Vierhapper, H | 2 |
| Nowotny, P | 2 |
| Waldhäusl, W | 1 |
| Heinze, G | 1 |
| Müssig, K | 1 |
| Remer, T | 1 |
| Haupt, A | 1 |
| Gallwitz, B | 1 |
| Fritsche, A | 1 |
| Häring, HU | 1 |
| Maser-Gluth, C | 1 |
| Stewart, PM | 1 |
| Boulton, A | 1 |
| Kumar, S | 1 |
| Clark, PM | 1 |
| Shackleton, CH | 1 |
| Tolis, G | 1 |
| Lewis, W | 1 |
| Verdy, M | 1 |
| Friesen, HG | 1 |
| Solomon, S | 1 |
| Pagalis, G | 1 |
| Pavlatos, F | 1 |
| Fessas, P | 1 |
| Rochefort, JG | 1 |
1 trial available for tetrahydrocortisol and Obesity
6 other studies available for tetrahydrocortisol and Obesity
| Article | Year |
|---|---|
Cortisol metabolism after weight loss: associations with 11 β-HSD type 1 and markers of obesity in women.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adult; Cohort Studies; Cortisone; Female; Humans; Hydro | 2013 |
Production rates of cortisol in obesity.
Topics: Adult; Androsterone; Etiocholanolone; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrocor | 2004 |
Sex-specific difference in the interconversion of cortisol and cortisone in men and women.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adult; Body Mass Index; Chromatography, Liquid; Cortiso | 2007 |
11beta-hydroxysteroid dehydrogenase 2 activity is elevated in severe obesity and negatively associated with insulin sensitivity.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adolescent; Adult; Case-Control Studies; Cortisone; Glo | 2008 |
Cortisol metabolism in human obesity: impaired cortisone-->cortisol conversion in subjects with central adiposity.
Topics: Adipose Tissue; Adult; Body Constitution; Body Mass Index; Cortisone; Female; Humans; Hydrocortisone | 1999 |
Anterior pituitary function in the Prader-Labhart-Willi (PLW) syndrome.
Topics: 17-Ketosteroids; Adolescent; Adult; Carbohydrate Metabolism, Inborn Errors; Chorionic Gonadotropin; | 1974 |