tetrahydrocortisol has been researched along with Kidney Failure, Chronic in 2 studies
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aldosterone has emerged as an important mediator of disease progression and mortality in patients with chronic heart and kidney disease (CKD)." | 2.75 | The effect of spironolactone upon corticosteroid hormone metabolism in patients with early stage chronic kidney disease. ( Edwards, NC; Ferro, CJ; Hammer, F; Hughes, BA; Steeds, RP; Stewart, PM; Townend, JN, 2010) |
| "Children suffering from chronic renal failure (CRF) have a decreased activity of 11beta-HSD2 contributing to increased arterial blood pressure." | 1.33 | Pediatric renal allograft transplantation does not normalize the increased cortisol/cortisone ratios of chronic renal failure. ( Dörr, HG; Dötsch, J; Plank, C; Rascher, W; Rauh, M; Schroth, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hammer, F | 1 |
| Edwards, NC | 1 |
| Hughes, BA | 1 |
| Steeds, RP | 1 |
| Ferro, CJ | 1 |
| Townend, JN | 1 |
| Stewart, PM | 1 |
| Schroth, M | 1 |
| Plank, C | 1 |
| Rauh, M | 1 |
| Dörr, HG | 1 |
| Rascher, W | 1 |
| Dötsch, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Is Spironolactone Safe and Effective in the Treatment of Cardiovascular Disease in Mild Chronic Renal Failure?[NCT00291720] | Phase 2 | 120 participants (Actual) | Interventional | 2005-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for tetrahydrocortisol and Kidney Failure, Chronic
| Article | Year |
|---|---|
The effect of spironolactone upon corticosteroid hormone metabolism in patients with early stage chronic kidney disease.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; H | 2010 |
1 other study available for tetrahydrocortisol and Kidney Failure, Chronic
| Article | Year |
|---|---|
Pediatric renal allograft transplantation does not normalize the increased cortisol/cortisone ratios of chronic renal failure.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adolescent; Blood Pressure; Child; Child, Preschool; Co | 2006 |