Page last updated: 2024-11-07

tetrahydrocortisol and Kidney Failure, Chronic

tetrahydrocortisol has been researched along with Kidney Failure, Chronic in 2 studies

Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
"Aldosterone has emerged as an important mediator of disease progression and mortality in patients with chronic heart and kidney disease (CKD)."2.75The effect of spironolactone upon corticosteroid hormone metabolism in patients with early stage chronic kidney disease. ( Edwards, NC; Ferro, CJ; Hammer, F; Hughes, BA; Steeds, RP; Stewart, PM; Townend, JN, 2010)
"Children suffering from chronic renal failure (CRF) have a decreased activity of 11beta-HSD2 contributing to increased arterial blood pressure."1.33Pediatric renal allograft transplantation does not normalize the increased cortisol/cortisone ratios of chronic renal failure. ( Dörr, HG; Dötsch, J; Plank, C; Rascher, W; Rauh, M; Schroth, M, 2006)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hammer, F1
Edwards, NC1
Hughes, BA1
Steeds, RP1
Ferro, CJ1
Townend, JN1
Stewart, PM1
Schroth, M1
Plank, C1
Rauh, M1
Dörr, HG1
Rascher, W1
Dötsch, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Is Spironolactone Safe and Effective in the Treatment of Cardiovascular Disease in Mild Chronic Renal Failure?[NCT00291720]Phase 2120 participants (Actual)Interventional2005-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for tetrahydrocortisol and Kidney Failure, Chronic

ArticleYear
The effect of spironolactone upon corticosteroid hormone metabolism in patients with early stage chronic kidney disease.
    Clinical endocrinology, 2010, Volume: 73, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; H

2010

Other Studies

1 other study available for tetrahydrocortisol and Kidney Failure, Chronic

ArticleYear
Pediatric renal allograft transplantation does not normalize the increased cortisol/cortisone ratios of chronic renal failure.
    European journal of endocrinology, 2006, Volume: 154, Issue:4

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adolescent; Blood Pressure; Child; Child, Preschool; Co

2006