tetrahydrocortisol has been researched along with Chronic Primary Open Angle Glaucoma in 3 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effectiveness of 3 alpha, 5 beta-tetrahydrocortisol (3 alpha, 5 beta-THF), a metabolite of cortisol, in lowering intraocular pressure (IOP) in rabbits made ocular hypertensive with glucocorticoids suggested its use in patients with Primary Open Angle Glaucoma (POAG)." | 3.69 | Treatment of glaucoma with 3 alpha, 5 beta-tetrahydrocortisol: a new therapeutic modality. ( Gordon, GG; Southren, AL; Wandel, T; Weinstein, BI, 1994) |
| "3 alpha, 5 beta-tetrahydrocortisol, previously considered an inactive metabolite of cortisol, was found to lower significantly the intraocular pressure (IOP) of rabbits made ocular hypertensive with dexamethasone alone or with threshold levels of dexamethasone plus 5 beta-dihydrocortisol." | 3.67 | Intraocular hypotensive effect of a topically applied cortisol metabolite: 3 alpha, 5 beta-tetrahydrocortisol. ( Gordon, GG; l'Hommedieu, D; Southren, AL; Weinstein, BI, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Southren, AL | 3 |
| Wandel, T | 1 |
| Gordon, GG | 3 |
| Weinstein, BI | 3 |
| Kandalaft, N | 1 |
| Ritch, R | 1 |
| Camras, CB | 1 |
| Morris, DJ | 1 |
| Latif, SA | 1 |
| Vecsei, P | 1 |
| Vittek, J | 1 |
| l'Hommedieu, D | 1 |
3 other studies available for tetrahydrocortisol and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
Treatment of glaucoma with 3 alpha, 5 beta-tetrahydrocortisol: a new therapeutic modality.
Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Drug Administration Schedule; Female; Gla | 1994 |
5 alpha-dihydrocortisol in human aqueous humor and metabolism of cortisol by human lenses in vitro.
Topics: Aged; Aqueous Humor; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Female; Glauc | 1991 |
Intraocular hypotensive effect of a topically applied cortisol metabolite: 3 alpha, 5 beta-tetrahydrocortisol.
Topics: Animals; Dexamethasone; Glaucoma, Open-Angle; Humans; Hydrocortisone; Intraocular Pressure; Ocular H | 1987 |