Page last updated: 2024-11-07

tetrahydrocortisol and Chronic Primary Open Angle Glaucoma

tetrahydrocortisol has been researched along with Chronic Primary Open Angle Glaucoma in 3 studies

Research Excerpts

ExcerptRelevanceReference
"The effectiveness of 3 alpha, 5 beta-tetrahydrocortisol (3 alpha, 5 beta-THF), a metabolite of cortisol, in lowering intraocular pressure (IOP) in rabbits made ocular hypertensive with glucocorticoids suggested its use in patients with Primary Open Angle Glaucoma (POAG)."3.69Treatment of glaucoma with 3 alpha, 5 beta-tetrahydrocortisol: a new therapeutic modality. ( Gordon, GG; Southren, AL; Wandel, T; Weinstein, BI, 1994)
"3 alpha, 5 beta-tetrahydrocortisol, previously considered an inactive metabolite of cortisol, was found to lower significantly the intraocular pressure (IOP) of rabbits made ocular hypertensive with dexamethasone alone or with threshold levels of dexamethasone plus 5 beta-dihydrocortisol."3.67Intraocular hypotensive effect of a topically applied cortisol metabolite: 3 alpha, 5 beta-tetrahydrocortisol. ( Gordon, GG; l'Hommedieu, D; Southren, AL; Weinstein, BI, 1987)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Southren, AL3
Wandel, T1
Gordon, GG3
Weinstein, BI3
Kandalaft, N1
Ritch, R1
Camras, CB1
Morris, DJ1
Latif, SA1
Vecsei, P1
Vittek, J1
l'Hommedieu, D1

Other Studies

3 other studies available for tetrahydrocortisol and Chronic Primary Open Angle Glaucoma

ArticleYear
Treatment of glaucoma with 3 alpha, 5 beta-tetrahydrocortisol: a new therapeutic modality.
    Journal of ocular pharmacology, 1994,Spring, Volume: 10, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Drug Administration Schedule; Female; Gla

1994
5 alpha-dihydrocortisol in human aqueous humor and metabolism of cortisol by human lenses in vitro.
    Investigative ophthalmology & visual science, 1991, Volume: 32, Issue:7

    Topics: Aged; Aqueous Humor; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Female; Glauc

1991
Intraocular hypotensive effect of a topically applied cortisol metabolite: 3 alpha, 5 beta-tetrahydrocortisol.
    Investigative ophthalmology & visual science, 1987, Volume: 28, Issue:5

    Topics: Animals; Dexamethasone; Glaucoma, Open-Angle; Humans; Hydrocortisone; Intraocular Pressure; Ocular H

1987