tetrahydrocortisol has been researched along with Depressive Disorder, Major in 2 studies
Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic stress as well as major depressive disorders is associated with cortisol metabolism." | 1.42 | A simple LC-MS/MS method for the determination of cortisol, cortisone and tetrahydro-metabolites in human urine: assay development, validation and application in depression patients. ( Chen, F; Lu, Y; Zhai, X; Zhu, C, 2015) |
| " The aim of this study was to determine whether in major depression changes in the activity patterns of local modulators of glucocorticoid action might contribute to an increase in cortisol bioavailability and if they change during antidepressant treatment and clinical response." | 1.35 | Cortisol metabolism in depressed patients and healthy controls. ( Deuschle, M; Frankhauser, P; Gilles, M; Hamann, B; Kopf, D; Lederbogen, F; Lewicka, S; Onken, V; Römer, B; Schilling, C, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhai, X | 1 |
| Chen, F | 1 |
| Zhu, C | 1 |
| Lu, Y | 1 |
| Römer, B | 1 |
| Lewicka, S | 1 |
| Kopf, D | 1 |
| Lederbogen, F | 1 |
| Hamann, B | 1 |
| Gilles, M | 1 |
| Schilling, C | 1 |
| Onken, V | 1 |
| Frankhauser, P | 1 |
| Deuschle, M | 1 |
2 other studies available for tetrahydrocortisol and Depressive Disorder, Major
| Article | Year |
|---|---|
A simple LC-MS/MS method for the determination of cortisol, cortisone and tetrahydro-metabolites in human urine: assay development, validation and application in depression patients.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adult; Cas | 2015 |
Cortisol metabolism in depressed patients and healthy controls.
Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tri | 2009 |