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tetraethylammonium and Hypoxia

tetraethylammonium has been researched along with Hypoxia in 35 studies

Tetraethylammonium: A potassium-selective ion channel blocker. (From J Gen Phys 1994;104(1):173-90)

Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.

Research Excerpts

ExcerptRelevanceReference
"During hypoxia, the level of adenosine in the carotid bodies increases as a result of ATP catabolism and adenosine efflux via adenosine transporters."3.73Adenosine stimulates depolarization and rise in cytoplasmic [Ca2+] in type I cells of rat carotid bodies. ( Tse, A; Tse, FW; Xu, F; Xu, J, 2006)
" The changes induced by hyperglycaemic hypoxia in low bicarbonate could be mimicked by exposure of the roots either to 100% CO2 or to a combination of 3 mM tetraethylammonium chloride and 3 mM 4-aminopyridine, to block both fast and slow potassium channels."3.69The effects of hyperglycaemic hypoxia on rectification in rat dorsal root axons. ( Bostock, H; Grafe, P; Schneider, U, 1994)
"9 microM), the Ca++ channel blocker verapamil (2 microM), and CaCl2 (6 mM) on a model of heart damage, hypoxia/reoxygenation of isolated guinea-pig hearts."3.67TEA prevents the decline of the duration of the action potential in hypoxic cardiac muscle. ( Asano, T; Kasuya, Y; Shigenobu, K, 1985)
"In the excised patch configuration anoxia had no effect on K(Ca) channel open probability (P(open)); however, in cell-attached mode, there was a reversible fivefold reduction in P(open) (from 0."1.39Oxygen-sensitive reduction in Ca²⁺-activated K⁺ channel open probability in turtle cerebrocortex. ( Buck, LT; Hogg, DW; Rodgers-Garlick, CI, 2013)
"1."1.28Ionic basis of membrane potential changes induced by anoxia in rat dorsal vagal motoneurones. ( Cowan, AI; Martin, RL, 1992)
"Reversible effects of brief periods of anoxia (replacing 95% O2-5% CO2 with 95% N2-5% CO2 for 2-4 min) were studied in CA1 neurons in hippocampal slices (from Sprague-Dawley rats), kept in an interface-type chamber at 33."1.28Hypoxic changes in hippocampal neurons. ( Krnjevic, K; Leblond, J, 1989)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19905 (14.29)18.7374
1990's19 (54.29)18.2507
2000's6 (17.14)29.6817
2010's5 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, D1
Liu, Y3
Lu, P1
Zhu, D1
Zhu, Y1
FREYBURGER, W1
CAPO, LR1
MOE, GK1
Zoer, B1
Cogolludo, AL1
Perez-Vizcaino, F1
De Mey, JG1
Blanco, CE1
Villamor, E1
Yoo, HY1
Park, SJ1
Bahk, JH1
Kim, SJ1
Hu, XQ1
Xiao, D1
Zhu, R1
Huang, X1
Yang, S1
Wilson, SM1
Zhang, L1
Rodgers-Garlick, CI1
Hogg, DW1
Buck, LT1
Fang, HS1
Northup, DW1
Van Liere, EJ1
BENKO, S1
EISNER, A1
SOLTESZ, R1
BENTZIK, M1
Karle, C1
Gehrig, T1
Wodopia, R1
Höschele, S1
Kreye, VA1
Katus, HA1
Bärtsch, P1
Mairbäurl, H1
Campanucci, VA1
Nurse, CA2
Xu, F1
Xu, J1
Tse, FW1
Tse, A1
Wasicko, MJ1
Breitwieser, GE1
Kim, I1
Carroll, JL1
Fu, XW2
Nurse, C1
Cutz, E2
Gebremedhin, D1
Bonnet, P1
Greene, AS1
England, SK1
Rusch, NJ3
Lombard, JH3
Harder, DR1
Grafe, P1
Bostock, H1
Schneider, U1
Reeves, WB1
Shah, SV1
Fredricks, KT2
Syková, E1
Svoboda, J1
Polák, J2
Chvátal, A1
Loutzenhiser, RD1
Parker, MJ1
Eddahibi, S1
Springall, D1
Mannan, M1
Carville, C1
Chabrier, PE1
Levame, M1
Raffestin, B1
Adnot, S1
Koong, AC1
Giaccia, AJ1
Hahn, GM1
Saad, AH1
Cornfield, DN1
Reeve, HL1
Tolarova, S1
Weir, EK1
Archer, S1
Buckler, KJ1
Lee, YH2
Kim, JT1
Kang, BS2
Seo, JH1
Barman, SA1
Wang, YT1
Bizub, DM1
Roman, RJ1
Huang, CC1
Hsu, KS1
Bartlett, IS1
Marshall, JM1
Cowan, AI1
Martin, RL1
Aitken, PG1
Jing, J1
Young, J1
Somjen, GG1
Hasunuma, K1
Yamaguchi, T1
Rodman, DM1
O'Brien, RF1
McMurtry, IF1
Leblond, J1
Krnjevic, K1
Asano, T1
Shigenobu, K1
Kasuya, Y1

Other Studies

35 other studies available for tetraethylammonium and Hypoxia

ArticleYear
15-oxo-ETE-induced internal carotid artery constriction in hypoxic rats is mediated by potassium channels.
    Physiological research, 2016, 07-18, Volume: 65, Issue:3

    Topics: 4-Aminopyridine; Animals; Arachidonic Acids; Carotid Artery, Internal; Glyburide; Hydroxyprostagland

2016
The effect of tetraethylammonium on the pressor response to anoxia and asphyxia.
    Federation proceedings, 1948, Volume: 7, Issue:1 Pt 1

    Topics: Asphyxia; Humans; Hypoxia; Tetraethylammonium; Vasoconstrictor Agents

1948
Hypoxia sensing in the fetal chicken femoral artery is mediated by the mitochondrial electron transport chain.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 298, Issue:4

    Topics: Animals; Antimycin A; Chick Embryo; Electron Transport; Femoral Artery; Hypoxia; Mitochondria; Nitra

2010
Inhibition of hypoxic pulmonary vasoconstriction of rats by carbon monoxide.
    Journal of Korean medical science, 2010, Volume: 25, Issue:10

    Topics: Animals; Carbon Monoxide; Guanylate Cyclase; Hypoxia; NG-Nitroarginine Methyl Ester; Nitric Oxide Sy

2010
Chronic hypoxia suppresses pregnancy-induced upregulation of large-conductance Ca2+-activated K+ channel activity in uterine arteries.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:1

    Topics: 4-Aminopyridine; Acclimatization; Altitude; Animals; Blotting, Western; Cells, Cultured; Chronic Dis

2012
Oxygen-sensitive reduction in Ca²⁺-activated K⁺ channel open probability in turtle cerebrocortex.
    Neuroscience, 2013, May-01, Volume: 237

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Biophysics; Calcium; Cerebral Cortex; Dose-Response R

2013
Combined effect of tetraethylammonium chloride and hypoxia on intestinal motility in rats.
    The American journal of physiology, 1953, Volume: 173, Issue:3

    Topics: Animals; Gastrointestinal Motility; Hypoxia; Intestines; Rats; Tetraethylammonium

1953
[Studies on the mechanism of action of experimental local bone marrow hypoxia with special reference to the role of the autonomic nervous system].
    Magyar belorvosi archivum es ideggyogyaszati szemle, 1954, Volume: 7, Issue:5

    Topics: Autonomic Nervous System; Bone Marrow; Ganglia; Ganglia, Autonomic; Humans; Hypoxia; Polycythemia; T

1954
Hypoxia-induced inhibition of whole cell membrane currents and ion transport of A549 cells.
    American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 286, Issue:6

    Topics: Cell Line, Tumor; Chlorides; Gene Expression; Humans; Hypoxia; Lung Neoplasms; Membrane Potentials;

2004
Biophysical characterization of whole-cell currents in O2-sensitive neurons from the rat glossopharyngeal nerve.
    Neuroscience, 2005, Volume: 132, Issue:2

    Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Cadmium; Calcium Channels; Cells, Cul

2005
Adenosine stimulates depolarization and rise in cytoplasmic [Ca2+] in type I cells of rat carotid bodies.
    American journal of physiology. Cell physiology, 2006, Volume: 290, Issue:6

    Topics: 4-Aminopyridine; Adenosine; Adenosine A2 Receptor Antagonists; Adenylyl Cyclases; Animals; Calcium;

2006
Postnatal development of carotid body glomus cell response to hypoxia.
    Respiratory physiology & neurobiology, 2006, Volume: 154, Issue:3

    Topics: 4-Aminopyridine; Aging; Animals; Animals, Newborn; Calcium; Carotid Body; Electric Capacitance; Elec

2006
Characterization of slowly inactivating KV{alpha} current in rabbit pulmonary neuroepithelial bodies: effects of hypoxia and nicotine.
    American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 293, Issue:4

    Topics: Animals; Cnidarian Venoms; Electric Conductivity; Female; Fluorescent Antibody Technique; Hypoxia; I

2007
Hypoxia increases the activity of Ca(2+)-sensitive K+ channels in cat cerebral arterial muscle cell membranes.
    Pflugers Archiv : European journal of physiology, 1994, Volume: 428, Issue:5-6

    Topics: Animals; Brain; Calcium Channels; Cats; Cell Hypoxia; Cell Membrane; Electric Conductivity; Female;

1994
The effects of hyperglycaemic hypoxia on rectification in rat dorsal root axons.
    The Journal of physiology, 1994, Oct-15, Volume: 480 ( Pt 2)

    Topics: 4-Aminopyridine; Animals; Diabetic Neuropathies; Electric Stimulation; Hexoses; Hydrogen-Ion Concent

1994
Activation of potassium channels contributes to hypoxic injury in proximal tubules.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:6

    Topics: Adenosine Triphosphate; Animals; Biological Transport; Diazoxide; DNA Damage; Dose-Response Relation

1994
Role of endothelium and arterial K+ channels in mediating hypoxic dilation of middle cerebral arteries.
    The American journal of physiology, 1994, Volume: 267, Issue:2 Pt 2

    Topics: Animals; Cerebral Arteries; Endothelium, Vascular; Glyburide; Hypoxia; In Vitro Techniques; Male; Ox

1994
Extracellular volume fraction and diffusion characteristics during progressive ischemia and terminal anoxia in the spinal cord of the rat.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1994, Volume: 14, Issue:2

    Topics: Animals; Diffusion; Extracellular Space; Female; Hypoxia; Ischemia; Potassium; Rats; Rats, Wistar; R

1994
Hypoxia inhibits myogenic reactivity of renal afferent arterioles by activating ATP-sensitive K+ channels.
    Circulation research, 1994, Volume: 74, Issue:5

    Topics: Adenosine Triphosphate; Animals; Arterioles; Glyburide; Hypoxia; Kidney; NAD; Potassium Channels; Ra

1994
Dilator effect of endothelins in pulmonary circulation: changes associated with chronic hypoxia.
    The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Autoradiograp

1993
Activation of potassium channels by hypoxia and reoxygenation in the human lung adenocarcinoma cell line A549.
    Journal of cellular physiology, 1993, Volume: 156, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcysteine; Adenocarcinoma; Alkaloids; Free Radic

1993
Oxygen causes fetal pulmonary vasodilation through activation of a calcium-dependent potassium channel.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Jul-23, Volume: 93, Issue:15

    Topics: Alkaloids; Aminoquinolines; Animals; Carbazoles; Charybdotoxin; Endothelium, Vascular; Enzyme Inhibi

1996
Role of potassium channels in hypoxic chemoreception in rat carotid body type-I cells.
    Advances in experimental medicine and biology, 1996, Volume: 410

    Topics: 4-Aminopyridine; Action Potentials; Animals; Carotid Body; Charybdotoxin; Hypoxia; Ion Channel Gatin

1996
Mechanisms of relaxation of coronary artery by hypoxia.
    Yonsei medical journal, 1998, Volume: 39, Issue:3

    Topics: Animals; Coronary Vessels; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Hypoxia; Indomethac

1998
Effects of hypoxia on pulmonary vascular contractility.
    Yonsei medical journal, 1998, Volume: 39, Issue:3

    Topics: Animals; Blood Vessels; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Hypo

1998
Potassium channels modulate hypoxic pulmonary vasoconstriction.
    The American journal of physiology, 1998, Volume: 275, Issue:1

    Topics: 4-Aminopyridine; Animals; Blood Pressure; Dogs; Female; Glyburide; Hypoxia; In Vitro Techniques; Mal

1998
Selective modulation of membrane currents by hypoxia in intact airway chemoreceptors from neonatal rabbit.
    The Journal of physiology, 1999, Jan-01, Volume: 514 ( Pt 1)

    Topics: 4-Aminopyridine; Animals; Animals, Newborn; Cadmium; Calcium; Calcium Channels; Carotid Body; Catech

1999
Electrical and mechanical responses of rat middle cerebral arteries to reduced PO2 and prostacyclin.
    The American journal of physiology, 1999, Volume: 276, Issue:2

    Topics: Animals; Cerebral Arteries; Electrophysiology; Epoprostenol; Glyburide; Hypoxia; Iloprost; In Vitro

1999
Protein tyrosine kinase is required for the induction of long-term potentiation in the rat hippocampus.
    The Journal of physiology, 1999, Nov-01, Volume: 520 Pt 3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Electric Stimulation; Enzyme Inhibitors; Excitatory

1999
Analysis of the effects of graded levels of hypoxia on noradrenaline-evoked contraction in the rat iliac artery in vitro.
    Experimental physiology, 2002, Volume: 87, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; Calcium Channel Blockers; Calcium

2002
Ionic basis of membrane potential changes induced by anoxia in rat dorsal vagal motoneurones.
    The Journal of physiology, 1992, Volume: 455

    Topics: 4-Aminopyridine; Action Potentials; Animals; Apamin; Hypoxia; Ions; Male; Manganese; Membrane Potent

1992
Ion channel involvement in hypoxia-induced spreading depression in hippocampal slices.
    Brain research, 1991, Feb-08, Volume: 541, Issue:1

    Topics: 4-Aminopyridine; Animals; Cortical Spreading Depression; Evoked Potentials; Female; Hippocampus; Hyp

1991
Effects of inhibitors of EDRF and EDHF on vasoreactivity of perfused rat lungs.
    The American journal of physiology, 1991, Volume: 260, Issue:2 Pt 1

    Topics: Analysis of Variance; Angiotensin II; Animals; Biological Factors; Blood Pressure; Glyburide; Hemogl

1991
Hypoxic changes in hippocampal neurons.
    Journal of neurophysiology, 1989, Volume: 62, Issue:1

    Topics: 4-Aminopyridine; Adenosine Triphosphate; Aminopyridines; Animals; Apamin; Caffeine; Calcium; Egtazic

1989
TEA prevents the decline of the duration of the action potential in hypoxic cardiac muscle.
    Japanese journal of pharmacology, 1985, Volume: 38, Issue:1

    Topics: Action Potentials; Animals; Calcimycin; Calcium Chloride; Guinea Pigs; Heart; Hypoxia; In Vitro Tech

1985