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tetraethylammonium and Glioma

tetraethylammonium has been researched along with Glioma in 15 studies

Tetraethylammonium: A potassium-selective ion channel blocker. (From J Gen Phys 1994;104(1):173-90)

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
" In this study, we investigated the antiproliferative effect of tetraethylammonium (TEA), a nonspecific potassium channel blocker, in rat C6 and 9L glioma cells."7.75Tetraethylammonium inhibits glioma cells via increasing production of intracellular reactive oxygen species. ( Hu, EX; Liu, BX; Liu, YH; Yang, KB; Zhao, SG, 2009)
"Tetraethylammonium ions inhibit the hyperpolarizing response of cells to bradykinin or inositol 1,4,5-trisphosphate."5.27Bradykinin-activated transmembrane signals are coupled via No or Ni to production of inositol 1,4,5-trisphosphate, a second messenger in NG108-15 neuroblastoma-glioma hybrid cells. ( Higashida, H; Klee, W; Nirenberg, M; Streaty, RA, 1986)
" In this study, we investigated the antiproliferative effect of tetraethylammonium (TEA), a nonspecific potassium channel blocker, in rat C6 and 9L glioma cells."3.75Tetraethylammonium inhibits glioma cells via increasing production of intracellular reactive oxygen species. ( Hu, EX; Liu, BX; Liu, YH; Yang, KB; Zhao, SG, 2009)
"Human malignant gliomas are highly invasive tumors."1.30Modulation of glioma cell migration and invasion using Cl(-) and K(+) ion channel blockers. ( Manning, TJ; Sontheimer, H; Soroceanu, L, 1999)
"Tetraethylammonium ions inhibit the hyperpolarizing response of cells to bradykinin or inositol 1,4,5-trisphosphate."1.27Bradykinin-activated transmembrane signals are coupled via No or Ni to production of inositol 1,4,5-trisphosphate, a second messenger in NG108-15 neuroblastoma-glioma hybrid cells. ( Higashida, H; Klee, W; Nirenberg, M; Streaty, RA, 1986)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19902 (13.33)18.7374
1990's7 (46.67)18.2507
2000's4 (26.67)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ru, Q1
Tian, X1
Wu, YX1
Wu, RH1
Pi, MS1
Li, CY1
Hu, L1
Li, LL1
Lin, ZG1
Jiang, ZC1
Li, HX1
Zhao, SG2
Yang, KB2
Liu, YH1
Hu, EX1
Liu, BX1
Sugimoto, N1
Ozutsumi, K1
Matsuda, M1
Higashida, H2
Miki, N1
Deegan, PM1
Pratt, IS1
Ryan, MP1
Hu, Q2
Shi, YL1
Huang, F1
Shi, Y1
Cachero, TG1
Morielli, AD1
Peralta, EG1
Soroceanu, L1
Manning, TJ1
Sontheimer, H2
Rouzaire-Dubois, B2
Milandri, JB1
Bostel, S1
Dubois, JM2
Philippe, JM1
Cartron, PF1
Vallette, F1
Morel, N1
Ransom, CB1
Liu, X1
Caulfield, MP1
Robbins, J1
Sim, JA1
Streaty, RA1
Klee, W1
Nirenberg, M1

Other Studies

15 other studies available for tetraethylammonium and Glioma

ArticleYear
Voltage-gated and ATP-sensitive K+ channels are associated with cell proliferation and tumorigenesis of human glioma.
    Oncology reports, 2014, Volume: 31, Issue:2

    Topics: 4-Aminopyridine; Animals; Apoptosis; Calcium; Calcium Signaling; Cell Line, Tumor; Cell Proliferatio

2014
Blockage of potassium channel inhibits proliferation of glioma cells via increasing reactive oxygen species.
    Oncology research, 2014, Volume: 22, Issue:1

    Topics: Acetylcysteine; Antioxidants; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependen

2014
Tetraethylammonium inhibits glioma cells via increasing production of intracellular reactive oxygen species.
    Chemotherapy, 2009, Volume: 55, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Glioma; Potassium Channe

2009
Action of tetanus toxin on cholinergic neuroblastoma X glioma hybrid cells: selective blockade of Ca spikes.
    Biken journal, 1983, Volume: 26, Issue:4

    Topics: Action Potentials; Animals; Calcium; Cell Line; Cell Membrane; Electrophysiology; Fluorescent Antibo

1983
The nephrotoxicity, cytotoxicity and renal handling of a cisplatin-methionine complex in male Wistar rats.
    Toxicology, 1994, Mar-25, Volume: 89, Issue:1

    Topics: Animals; Antineoplastic Agents; Biological Transport; Cisplatin; Drug Combinations; Glioma; In Vitro

1994
Characterization of an inward-rectifying potassium current in NG108-15 neuroblastoma x glioma cells.
    Pflugers Archiv : European journal of physiology, 1997, Volume: 433, Issue:5

    Topics: 4-Aminopyridine; Barium; Bucladesine; Cadmium; Calcium; Cell Differentiation; Cesium; Cobalt; Cyclic

1997
Inhibition of Toosendanin on the delayed rectifier potassium current in neuroblastoma x glioma NG108-15 cells.
    Brain research, 1997, Mar-14, Volume: 751, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1997
The small GTP-binding protein RhoA regulates a delayed rectifier potassium channel.
    Cell, 1998, Jun-12, Volume: 93, Issue:6

    Topics: ADP Ribose Transferases; Animals; Botulinum Toxins; Carbachol; Cell Membrane; Cells, Cultured; Enzym

1998
Modulation of glioma cell migration and invasion using Cl(-) and K(+) ion channel blockers.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Jul-15, Volume: 19, Issue:14

    Topics: Adult; Aged; Animals; Biopsy; Brain; Cell Aggregation; Cell Movement; Child, Preschool; Chloride Cha

1999
Control of cell proliferation by cell volume alterations in rat C6 glioma cells.
    Pflugers Archiv : European journal of physiology, 2000, Volume: 440, Issue:6

    Topics: Animals; Cell Division; Cell Size; Cesium; Charybdotoxin; Chloride Channels; Culture Media; Egtazic

2000
Functional expression of V-ATPases in the plasma membrane of glial cells.
    Glia, 2002, Mar-15, Volume: 37, Issue:4

    Topics: Angiogenesis Inhibitors; Animals; Astrocytes; Brain Neoplasms; Cell Membrane; Central Nervous System

2002
BK channels in human glioma cells have enhanced calcium sensitivity.
    Glia, 2002, Volume: 38, Issue:4

    Topics: Alkaloids; Benzylisoquinolines; Brain Neoplasms; Calcium; Calcium Channel Blockers; Calcium Signalin

2002
Muscarinic receptor-mediated inhibition of voltage-activated Ca current in neuroblastoma x glioma hybrid (NG 108-15) cells--reduction of muscarinic agonist and antagonist potency by tetraethylammonium (TEA).
    Neuroscience letters, 1991, Jun-24, Volume: 127, Issue:2

    Topics: Acetylcholine; Action Potentials; Atropine; Calcium; Glioma; Humans; Hybridization, Genetic; Neurobl

1991
A transient outward current in NG108-15 neuroblastoma x glioma hybrid cells.
    Pflugers Archiv : European journal of physiology, 1990, Volume: 416, Issue:1-2

    Topics: 4-Aminopyridine; Action Potentials; Adrenergic Fibers; Animals; Barium; Calcium; Elapid Venoms; Glio

1990
Bradykinin-activated transmembrane signals are coupled via No or Ni to production of inositol 1,4,5-trisphosphate, a second messenger in NG108-15 neuroblastoma-glioma hybrid cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:4

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Bradykinin; Calcium; Cell Line; Diglycerides;

1986