tetraethylammonium has been researched along with Endotoxemia in 3 studies
Tetraethylammonium: A potassium-selective ion channel blocker. (From J Gen Phys 1994;104(1):173-90)
Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of K(ATP) channels in the antiarrhythmic effect of Escherichia coli endotoxin-induced nitric oxide synthase (iNOS) was examined in an anesthetised rat model of myocardial ischemia and reperfusion arrhythmia by using glibenclamide (1 mg kg(-1)), nateglinide (10 mg kg(-1)) and repaglinide (0." | 3.74 | Glibenclamide attenuates the antiarrhythmic effect of endotoxin with a mechanism not involving K(ATP) channels. ( Erkent, U; Ertunc, M; Guc, MO; Ilhan, M; Iskit, AB; Onur, R, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pickkers, P | 1 |
| Dorresteijn, MJ | 1 |
| Bouw, MP | 1 |
| van der Hoeven, JG | 1 |
| Smits, P | 1 |
| Iskit, AB | 1 |
| Erkent, U | 1 |
| Ertunc, M | 1 |
| Guc, MO | 1 |
| Ilhan, M | 1 |
| Onur, R | 1 |
| da Silva-Santos, JE | 1 |
| Terluk, MR | 1 |
| Assreuy, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Blockade of Vascular Potassium Channels During Human Endotoxemia[NCT00185003] | Phase 1 | 36 participants (Actual) | Interventional | 2003-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for tetraethylammonium and Endotoxemia
| Article | Year |
|---|---|
In vivo evidence for nitric oxide-mediated calcium-activated potassium-channel activation during human endotoxemia.
Topics: Adult; Dose-Response Relationship, Drug; Endotoxemia; Endotoxins; Enzyme Inhibitors; Escherichia col | 2006 |
2 other studies available for tetraethylammonium and Endotoxemia
| Article | Year |
|---|---|
Glibenclamide attenuates the antiarrhythmic effect of endotoxin with a mechanism not involving K(ATP) channels.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Blood Pressure; Carbamates | 2007 |
Differential involvement of guanylate cyclase and potassium channels in nitric oxide-induced hyporesponsiveness to phenylephrine in endotoxemic rats.
Topics: Animals; Aorta; Blood Pressure; Dose-Response Relationship, Drug; Endotoxemia; Guanylate Cyclase; In | 2002 |