tetraethylammonium has been researched along with Alzheimer Disease in 7 studies
Tetraethylammonium: A potassium-selective ion channel blocker. (From J Gen Phys 1994;104(1):173-90)
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Several alterations in fibroblasts of Alzheimer's disease (AD) patients have been described, including alterations in calcium regulation, protein kinase C (PKC), and potassium (K+) channels." | 1.30 | Restoration of TEA-induced calcium responses in fibroblasts from Alzheimer's disease patients by a PKC activator. ( Bhagavan, S; Etcheberrigaray, R; Ibarreta, D; Kozikowski, AP; Ma, D, 1998) |
| "A tetraethylammonium-induced increase of intracellular concentrations of calcium, [Ca2+]i, a response that depends on functional 113-picosiemen potassium channels, was also eliminated or markedly reduced by 10 nM beta-amyloid." | 1.29 | Soluble beta-amyloid induction of Alzheimer's phenotype for human fibroblast K+ channels. ( Alkon, DL; Etcheberrigaray, R; Ito, E; Kim, CS, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (85.71) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Etcheberrigaray, R | 4 |
| Ito, E | 2 |
| Kim, CS | 1 |
| Alkon, DL | 3 |
| Oka, K | 1 |
| Tofel-Grehl, B | 1 |
| Gibson, GE | 1 |
| Sanderson, KL | 1 |
| Butler, L | 1 |
| Ingram, VM | 1 |
| Eckert, A | 1 |
| Oster, M | 1 |
| Förstl, H | 1 |
| Hennerici, M | 1 |
| Müller, WE | 1 |
| Hirashima, N | 1 |
| Nee, L | 1 |
| Prince, J | 1 |
| Govoni, S | 1 |
| Racchi, M | 1 |
| Tanzi, RE | 1 |
| Bhagavan, S | 1 |
| Ibarreta, D | 1 |
| Ma, D | 1 |
| Kozikowski, AP | 1 |
| Jhamandas, JH | 1 |
| Harris, KH | 1 |
| MacTavish, D | 1 |
| Jassar, BS | 1 |
7 other studies available for tetraethylammonium and Alzheimer Disease
| Article | Year |
|---|---|
Soluble beta-amyloid induction of Alzheimer's phenotype for human fibroblast K+ channels.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Bombesin; Calcium; Cell Line; Cells, Cultured; Dimethyl Su | 1994 |
Potassium channel dysfunction in fibroblasts identifies patients with Alzheimer disease.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Calcium; Cell Line; Cells, Cultured; Female; Fibr | 1993 |
Aggregates of a beta-amyloid peptide are required to induce calcium currents in neuron-like human teratocarcinoma cells: relation to Alzheimer's disease.
Topics: Aluminum; Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Calcium; Electric Conductiv | 1997 |
Impaired calcium regulation in subcortical vascular encephalopathy.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Brain; Calcium; Dementia, Vascula | 1997 |
Calcium responses in fibroblasts from asymptomatic members of Alzheimer's disease families.
Topics: Alzheimer Disease; Bradykinin; Calcium; Cells, Cultured; Fibroblasts; Humans; Intracellular Membrane | 1998 |
Restoration of TEA-induced calcium responses in fibroblasts from Alzheimer's disease patients by a PKC activator.
Topics: Alzheimer Disease; Calcium; Carcinogens; Cells, Cultured; Dimethyl Sulfoxide; Enzyme Activation; Exc | 1998 |
Novel excitatory actions of galanin on rat cholinergic basal forebrain neurons: implications for its role in Alzheimer's disease.
Topics: Acetylcholine; Action Potentials; Alzheimer Disease; Animals; Barium; Choline O-Acetyltransferase; C | 2002 |