tetraethyl lead has been researched along with TDP-43 Proteinopathies in 1 studies
*TDP-43 Proteinopathies: Diseases characterized by the presence of abnormally phosphorylated, ubiquitinated, and cleaved DNA-binding protein TDP-43 in affected brain and spinal cord. Inclusions of the pathologic protein in neurons and glia, without the presence of AMYLOID, is the major feature of these conditions, thus making these proteinopathies distinct from most other neurogenerative disorders in which protein misfolding leads to brain amyloidosis. Both frontotemporal lobar degeneration and AMYOTROPHIC LATERAL SCLEROSIS exhibit this common method of pathogenesis and thus they may represent two extremes of a continuous clinicopathological spectrum of one disease. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, Z; Fuller-Thomson, E | 1 |
1 other study(ies) available for tetraethyl lead and TDP-43 Proteinopathies
| Article | Year |
|---|---|
Could Lifetime Lead Exposure Play a Role in Limbic-predominant Age-related TDP-43 Encephalopathy (LATE)?
Topics: Adult; Aged; Aged, 80 and over; Autopsy; Dementia; DNA-Binding Proteins; Environmental Exposure; Female; Half-Life; Homeostasis; Humans; Lead; Lead Poisoning, Nervous System; Limbic System; Male; Middle Aged; TDP-43 Proteinopathies; Tetraethyl Lead; Tibia | 2020 |