tetradecanoylphorbol acetate has been researched along with Papilloma in 525 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 160 (30.48) | 18.7374 |
| 1990's | 188 (35.81) | 18.2507 |
| 2000's | 120 (22.86) | 29.6817 |
| 2010's | 54 (10.29) | 24.3611 |
| 2020's | 3 (0.57) | 2.80 |
| Authors | Studies |
|---|---|
| González-Rodríguez, M; Hiihtola, L; Järvinen, TAH; Junttila, IS; Kummola, L; Määttä, J; Parviainen, L; Pemmari, T; Salomaa, T; Salonen, N; Vähätupa, M | 1 |
| Ghadi, DS; Joshi, P; Waghmare, SK | 1 |
| Aird, KM; Buj, R; Chen, CW; Dahl, ES; Hobbs, RP; Imamura-Kawasawa, Y; Kossenkov, AV; Leon, KE; Lesko, E; Tangudu, NK | 1 |
| Anguish, LJ; Coonrod, SA; Horibata, S; McElwee, JL; McLean, D; Mohanan, S; Mukai, C; Sams, K; Yan, A | 1 |
| Patial, V; Sharma, S; Sk, UH | 1 |
| Aguilar-Pimentel, JA; Beck, PJ; Fuchs, H; Gailus-Durner, V; Garman, KA; Hrabe de Angelis, M; Lee, YG; Ollert, M; Riegel, AT; Schmidt, MO; Schmidt-Weber, C; Tan, M; Tassi, E; Wellstein, A; Zuo, C | 1 |
| Asfaha, S; Boland, K; Gordon, D; Jin, G; Johnson, K; Lad, S; Londono, D; Morris, RJ; Park, H; Patterson, KS; Readio, N; Singh, A; Trempus, C; Wang, TC; Yang, X | 1 |
| Colombo, D; Gagliardi, C; Konoshima, T; Ronchetti, F; Suzuki, N; Takasaki, M; Tokuda, H; Vetro, M | 1 |
| Amaral, L; Engi, H; Hamilton, G; Hohmann, J; Maoka, T; Molnar, J; Mucsi, I; Olszewski, U; Suzuiki, N; Tokuda, H; Vasas, A | 1 |
| Ichiishi, E; Iida, A; Kapadia, GJ; Konoshima, T; Rao, GS; Sridhar, R; Suzuki, N; Takasaki, M; Tokuda, H | 1 |
| Chen, L; Ghosh, S; Hayden, MS; Jimi, E; Pentland, AP; Poligone, B | 1 |
| Belai, EB; Campanelli, AP; Cavassani, KA; de Oliveira, CE; Garlet, GP; Gasparoto, TH; Ramos, RN; Silva, JS; Torres, SA | 1 |
| Fujiwara, K; Ghosh, S; Liang, P; Morien, E; Nagase, H; Soma, M | 1 |
| Ahn, JS; Bode, AM; Choi, TW; Dong, Z; Erikson, RL; Huang, Z; Hwang, J; Jang, JH; Kim, BY; Lee, KW; Li, W; Liu, H; Liu, K; Ryoo, IJ; Thimmegowda, NR; Yang, Y; Zhou, X | 1 |
| Angel, JM; Beltran, L; Blando, J; Checkley, LA; Cho, J; DiGiovanni, J; Hursting, SD; Rho, O | 1 |
| Antsiferova, M; Feyerabend, TB; Förster, A; Hartmann, K; Hohl, D; Huber, M; Martin, C; Rodewald, HR; Werner, S | 1 |
| Chen, X; Fagin, JA; Johnson, LK; Knauf, JA; Makarewicz, JM | 1 |
| Baban, B; Chandler, P; DuHadaway, JB; Keough, MP; Mandik-Nayak, L; Mellor, AL; Merlo, LM; Metz, R; Muller, AJ; Pigott, E; Prendergast, GC; Rust, S; Smith, C | 1 |
| Blankenstein, T; Bozrova, SV; Chashchina, AA; Drutskaya, MS; Kammertoens, T; Nedospasov, SA; Qin, Z; Quarcoo, D; Rothe, M | 1 |
| Becker, K; Kaina, B; Thomas, AD | 1 |
| Cipolat, S; Hoste, E; Natsuga, K; Quist, SR; Watt, FM | 1 |
| Cha, IH; Cho, SB; Choi, EJ; Kim, J; Kim, KY; Zhang, X; Zheng, Z; Zhu, L | 1 |
| Aoto, Y; Goitsuka, R; Hachiya, T; Hirose, S; Isogai, E; Katsuragi, Y; Kominami, R; Nakamura, T; Okumura, K; Saito, M; Sakakibara, Y; Wakabayashi, Y | 1 |
| García-Fernández, RA; García-Iglesias, MJ; Pérez-Martínez, C | 1 |
| Catapang, A; Dennis, EA; Dumlao, DS; Fischer, SM; Herschman, HR; Ishikawa, TO; Jiao, J; Magyar, CE; Mikulec, C; Norris, PC | 1 |
| Asano, R; Iizuka, H; Nakae, Y; Nakajima, S; Ogasawara, K; Sakata, I; Takahashi, H | 1 |
| Brady, M; Brennan-Crispi, DM; Hossain, C; Mahoney, MG; Riobo, NA; Sahu, J | 1 |
| Järvinen, TA; Laitinen, AM; May, U; Nieminen, K; Prince, S; Uusitalo-Järvinen, H; Vähätupa, M | 1 |
| Bao, R; Bechill, J; Bindokas, VP; Faber, PW; Lingen, MW; Spiotto, MT; Zhong, R | 1 |
| Beck, A; Fletcher, S; Goldstein, J; Horsley, V; Lin, S; Roberts, N; Roth, E; Suárez-Fariñas, M; Tadeu, A; Wu, C; Zeiss, C; Zwick, R | 1 |
| Bazzocchi, IL; Chavez-Sifontes, M; Ichiishi, E; Jiménez, IA; Martinez, ML; Mendoza, CR; Núñez, MJ; Tokuda, H; Tokuda, R | 1 |
| Hermeking, H; Lodygin, D; Verdoodt, B; Winter, M | 1 |
| Dai, X; Dang, Y; Gu, J; Liu, M; Liu, X; Ren, X; Wang, L; Xu, P; Ye, X | 1 |
| Asai, M; Asai, N; Enomoto, A; Kato, T; Mii, S; Murakumo, Y; Nagino, M; Shiraki, Y; Sunagawa, M; Takahashi, M | 1 |
| Chandler, PR; Duhadaway, JB; Everhart, ME; Johnson, BA; Kahler, DJ; Mellor, AL; Muller, AJ; Munn, DH; Pihkala, J; Prendergast, GC; Sharma, MD; Soler, AP | 1 |
| Ashton, GH; Baldeschi, C; Brunton, VG; Canel, M; Doyle, B; Frame, MC; Green, TP; Mackintosh, LJ; Mason, SM; Sansom, OJ; Serrels, A; Serrels, B | 1 |
| Katiyar, SK; Meeran, SM; Punathil, T; Vaid, M | 1 |
| Li, Z; Qin, Z; Wang, C; Xiao, M; Zhang, J; Zhao, X | 1 |
| Abdul-Karim, FW; Fu, W; Gibbons, HE; Gorodeski, GI; Li, X; Luo, L; McCormick, T; Qi, X; Wang, BC; Zhou, L | 1 |
| Barragan, DI; Charron, J; Dumesic, PA; Harada, K; Khavari, PA; Scholl, FA | 1 |
| Asano, R; Iizuka, H; Nakae, Y; Nakajima, S; Sakata, I; Takahashi, H | 2 |
| Glick, A; Moitra, J; Orosz, A; Rishi, V; Rozenberg, J; Vinson, C | 1 |
| Dziadziuszko, H; Glosnicka, R; Graczyk, A; Jankowski, D; Jaskiewicz, K; Juzeniene, A; Kaliszewski, M; Kunikowska, D; Kwasny, M; Kwitniewski, M; Ma, LW; Moan, J; Peksa, R | 1 |
| Hosseini, ST; Iranshahi, M; Konoshima, T; Sahebkar, A; Takasaki, M; Tokuda, H | 1 |
| Chun, KS; Langenbach, R; Lao, HC; Okada, M; Trempus, CS | 1 |
| In, Y; Tanaka, R; Tokuda, H; Wada, S; Yamada, T; Yamaguchi, C | 1 |
| Honeycutt, KA; Koster, MI; Roop, DR; Waikel, RL; Wang, XJ | 1 |
| Fischer, SM; Herschman, HR; Huang, SC; Ishikawa, TO; Kumar, IP; Kusewitt, D; Machado, HB; Wong, KP | 1 |
| Glick, AB; Hogan, KA; Markell, LM; Pérez-Lorenzo, R; Yuspa, SH | 1 |
| Cabrera, WH; Dragani, TA; Galvan, A; Ibañez, OM; Mancuso, M; Milani, S; Pazzaglia, S; Ribeiro, OG; Saran, A; Vorraro, F; Zolin, A | 1 |
| Kim, EJ; Kim, J; Park, H; Park, JH | 1 |
| Glick, AB; Kennett, MJ; Masiuk, KE; Mordasky Markell, L; Pérez-Lorenzo, R | 1 |
| Akakura, S; Bouchard, R; Bshara, W; Gelman, IH; Morrison, C | 1 |
| Dahlhoff, M; Rose, C; Schneider, MR; Wolf, E | 1 |
| Ikeuchi, H; Kinjo, T; Klinman, DM | 1 |
| Anson, RM; de Cabo, R; Diéguez, C; Jones, B; López, M; Minor, RK; Pearson, KJ; Younts, CM | 1 |
| Benavides, F; Blando, J; Conti, CJ; Contreras, O; Coussens, LM; DiGiovanni, J; Fischer, SM; Kusewitt, DF; Perez, C; Shen, J | 1 |
| Athar, M; Kopelovich, L | 1 |
| Checkley, LA; DiGiovanni, J; Hursting, S; Moore, T; Rho, O | 1 |
| Chakravarty, P; Henderson, CJ; McLaren, A; Ritchie, KJ; Wolf, CR | 1 |
| Chaiswing, L; Dhar, SK; Oberley, TD; St Clair, DK; Tangpong, J | 1 |
| Bohrman, JS; Fischer, SM; Gleason, GL; Hardin, LG; Slaga, TJ | 1 |
| Boutwell, RK; Verma, AK | 2 |
| Bendt, KM; Edwards, RH; Moore, DT; Nielsen, JN; Raab-Traub, N; Shair, KH | 1 |
| Cotsarelis, G; Gordon, D; Li, S; Liu, Y; Morris, RJ; Park, H; Trempus, CS | 1 |
| Gong, Z; Li, A; Li, G; Li, X; Shi, Y; Ye, Y; Zhang, J; Zhou, J; Zhu, Z | 1 |
| Kominami, R; Mao, JH; Miura, I; Miyasaka, Y; Okumura, K; Saito, M; Sato, M; Wakabayashi, Y; Wakana, S | 1 |
| Clarke, M; Das, S; Huels, D; Jamieson, T; Jung, A; Neumann, J; Nibbs, RJ; Olson, MF; Samuel, MS; Sansom, OJ; Steele, CW | 1 |
| Braeuning, A; Münzel, PA; Schwarz, M | 1 |
| Wolf, G | 1 |
| Fürstenberger, G; Heidt, M; Krieg, P; Marks, F; Müller, K; Siebert, M | 1 |
| Berger, I; Furstenberger, G; Marks, F; Muller-Decker, K; Neufang, G; Neumann, M | 1 |
| Bishop, A; Fontaine, K; Lebel, M; Leder, A; Leder, P; Zhou, F | 1 |
| Athar, M; Bhasin, G; Kausar, H; Sarwar Alam, M | 1 |
| Alexander, A; Allen, SM; Altieri, DC; Diedrich, MJ; Florell, SR; Grossman, D; Hanks, AN | 1 |
| Dwivedi, C; Goetz-Parten, DE; Guan, X; Harmsen, WL; Johnson, KM; Koopman, EM; Matthees, DP; Valluri, HB; Voss, AL | 1 |
| Ichiishi, E; Ishikawa, T; Kokura, S; Kuchide, M; Naito, Y; Nishino, H; Tokuda, H; Toyokuni, S; Yoshida, N; Yoshikawa, T | 1 |
| Kannan, S; Kirtane, BM; Mansukhani, NP; Mulherkar, R; Naresh, KN; Ramchandani, A | 1 |
| Kawashima, Y; Kitajima, S; Mitsuoka, C; Ohara, M; Watanabe, H | 1 |
| Arnott, CH; Balkwill, FR; East, N; Moore, RJ; Scallon, BJ; Scott, KA; Shealy, DJ; Thompson, RG | 1 |
| Iida, A; Kaneko, M; Konishi, K; Kumeda, Y; Nishino, H; Tokuda, H; Tomioka, K | 1 |
| Kupper, TS; Morales, RE; Murphy, JE; Scott, J | 1 |
| Lin, KK; Rosenzweig, BA; Sistare, FD; Thompson, KL; Weaver, JL; Zhang, J | 1 |
| Eferl, R; Frank, C; Kenner, L; Martin, P; Scheuch, H; Sibilia, M; Wagner, EF; Zenz, R | 1 |
| Bu, P; Nishino, H; Okuda, M; Satomi, Y; Tokuda, H | 1 |
| Filler, RB; Girardi, M; Glusac, E; Hayday, AC; Lewis, J; Propperova, I; Roberts, SJ; Tigelaar, RE | 1 |
| Bernabéu, C; Letarte, M; López-Novoa, JM; Pérez-Gómez, E; Quintanilla, M; Ramirez, JR; Romero, D; Velasco, B | 1 |
| De-Carvalho, RR; De-Oliveira, AC; Delgado, IF; Kuriyama, SN; Oliveira-Filho, EC; Paumgartten, FJ; Souza, CA | 1 |
| Athar, M; Bhasin, G; Kauser, H | 2 |
| Ishikawa, Y; Matsunaga, S; Minami, T; Minoura, K; Tanaka, R; Tokuda, H | 1 |
| Akihisa, T; Banno, N; Hasegawa, J; Higashihara, H; Kimura, Y; Nishino, H; Tokuda, H; Ukiya, M; Watanabe, K; Yasukawa, K | 1 |
| Covelli, V; Di Majo, V; Mancuso, M; Pazzaglia, S; Rebessi, S; Saran, A; Tanori, M | 1 |
| Bair, W; Barbercheck, L; Bhattacharyya, AK; Mustacich, D; Powis, G; Stratton, SP; Wagner, A; Williams, R | 1 |
| Chun, KS; Lee, E; Lee, LJ; Lee, SS; Park, KK; Surh, YJ | 1 |
| Balmain, A; Del Rosario, R; Mao, JH; Perez-Losada, J; To, MD; Wu, D | 1 |
| Bang, YJ; Chun, KS; Chung, WY; Lee, JY; Park, KK; Shin, JW; Sung, JH; Surh, YJ | 1 |
| Benavides, F; Fischer, SM; Kim, E; Newman, RA; Rundhaug, JE; Yang, P | 1 |
| Kinouchi, Y; Tanaka, R; Tokuda, H; Wada, S | 1 |
| Beguinot, F; Formisano, P; Libertini, S; Miele, C; Oriente, F; Perruolo, G; Portella, G; Raciti, GA; Santopietro, S; Troncone, G | 1 |
| Attardi, LD; Bronson, RT; Horner, JS; Ihrie, RA; Marques, MR | 1 |
| Aoki, I; Colledge, WH; Foidart, JM; Hata, R; Kato, Y; Koshika, S; Kubota, Y; Nagashima, Y; Sakai, N; Thompson, EW; Tsukuda, M; Yao, M | 1 |
| Abdel-Fattah, R; Glick, A; Hennings, H; Maiberger, P; Rehman, I | 1 |
| Clarke, SL; Filler, R; Girardi, M; Hayday, AC; Lewis, JM; Oppenheim, DE; Roberts, SJ; Tigelaar, RE | 1 |
| Chan, T; Fuhrman, J; Hansen, LA; Repertinger, S; Shafer, L | 1 |
| Akazawa, H; Akihisa, T; Banno, N; Kimura, Y; Nishino, H; Suzuki, T; Taguchi, Y; Tokuda, H; Ukiya, M; Yasukawa, K | 1 |
| Fukuda, Y; Matsunaga, S; Sakai, K; Tanaka, R; Tokuda, H | 1 |
| Alexander, CL; Greenhalgh, DA; Porter, MJ; Quinn, JA; Wu, H; Yao, D | 1 |
| Davies, R; Edwards, RE; Gant, TW; Greaves, P; Ridd, K; Smith, AG; Wolfreys, A; Zhang, SD | 1 |
| Chang, PL; Elmets, C; Feng, G; Hicks, PH; Hsieh, YH; Juliana, MM; Liaw, L | 1 |
| Ho, CT; Lai, CS; Pan, MH; Wang, YJ | 1 |
| Chan, EL; Collins, MH; Kader, SA; Pathrose, P; Peace, BE; Toney, K; Waltz, SE | 1 |
| Choi, HG; Kim, JA; Kim, SJ; Lee, ES; Lee, YS; Paek, SH; Park, BC; Yong, CS | 1 |
| Castranova, V; Kisin, ER; Kommineni, C; Murray, AR; Shvedova, AA; Vallyathan, V | 1 |
| Antal, MC; Castaneda, E; Chambon, P; Desvergne, B; Gariglio, P; Indra, AK; Jiang, M; Kato, S; Loehr, CV; Meng, X; Messaddeq, N; Metzger, D; Wahli, W | 1 |
| Dwivedi, C; Fahmy, H; Khalifa, S; Kundoor, V; Zeman, D; Zhang, X | 1 |
| Bhattacharyya, AK; Chandramouli, A; Feng, Y; Holubec, H; Nelson, MA; Shanas, RM; Shi, J; Zheng, W | 1 |
| Bae, DS; Darwiche, N; Glick, AB; Hennings, H; Perez-Lorenzo, R; Ryscavage, A; Wright, L; Yuspa, SH | 1 |
| Fujiwara, K; Igarashi, J; Irahara, N; Kimura, M; Nagase, H | 1 |
| Ferra, A; Forrow, S; Gilchrist, DS; Graham, GJ; Hunter, KD; King, V; Nibbs, RJ | 1 |
| Horie, S; Katsuki, M; Muto, S | 1 |
| Espinosa-Alvarez, J; García-Fernández, RA; García-Iglesias, MJ; Pérez-Martínez, C | 1 |
| Bustos, T; Fischer, SM; Hu, Y; Liu, B; Park, E; Shen, J; Xia, X; Zhu, F | 1 |
| Nafz, J; Nindl, I; Ohnesorge, M; Rösl, F; Stockfleth, E | 1 |
| Ananthaswamy, HN; Li, Y; Oberley, TD; Verma, AK; Wheeler, DL | 1 |
| Chiappetta, G; Costinean, S; Croce, CM; De Martino, I; Fedele, M; Fusco, A; Iuliano, R; Kusewitt, DF; Oberyszyn, TM; Palmieri, D; Server, IN; Visone, R | 1 |
| Bhoumik, A; Breitwieser, W; Davis, S; Derossi, C; Fichtman, B; Jones, N; Kluger, HM; Krajewski, S; Meltzer, P; Ronai, Z; Subtil, A | 1 |
| Colombo, D; Ferraboschi, P; Franchini, L; Nishino, H; Takayasu, J; Tokuda, H | 1 |
| Ezaki, Y; Tanaka, R; Tokuda, H | 1 |
| Iijima, M; Oguro, T; Sueki, H; Yajima, Y; Yoshida, T | 1 |
| Belman, S; Garte, SJ | 2 |
| Iversen, OH | 3 |
| Hennings, H; Kulesz-Martin, M; Lichti, U; Yuspa, SH | 1 |
| Boutwell, RK; Perchellet, JP | 1 |
| Nelson, KG; Slaga, TJ | 1 |
| Klein-Szanto, AJ; Nelson, KG; Shah, Y; Slaga, TJ | 1 |
| Pashko, LL; Rovito, RJ; Schwartz, AG; Sobel, EL; Williams, JR | 1 |
| Burns, JC; Murray, BK | 1 |
| Boutwell, RK; Conrad, EA; Verma, AK | 1 |
| Albert, RE; Burns, FJ | 1 |
| Yuspa, SH | 1 |
| Bernfeld, P; Homburger, F | 1 |
| Ashendel, CL; Boutwell, RK; Garcia, CT; Verma, AK | 1 |
| Albert, RE; Burns, FJ; Morris, EP | 1 |
| Kato, R; Nakadate, T; Sugimura, T; Yamamoto, S | 1 |
| Astrup, EG; Iversen, OH | 2 |
| Boutwell, RK; Perrella, FW | 1 |
| Stenbäck, F | 2 |
| Boger, E; Moolten, FL; Rizzone, A; Schreiber, B; Weiss, AJ | 1 |
| Peto, R; Shubik, P; Stenbäck, F | 1 |
| Donahoe, R; Ferguson, E; Geusz, S; Hennings, H; Spangler, EF; Wenk, M; Yuspa, SH | 1 |
| Buhler, DR; Chang, RL; Conney, AH; Jerina, DM; Levin, W; Newman, MS; O'Malley, RF; Slaga, TJ; Wood, AW | 1 |
| Clark, JN; Levin, LV; Newberne, PM; Quill, HR; Wolf, G | 1 |
| Boutwell, RK; DiGiovanni, J | 1 |
| Melchionne, S; Van Duuren, BL | 1 |
| Bush, DM; Kensler, TW; Kozumbo, WJ | 1 |
| Fischer, SM; Hardin, LG; Slaga, TJ | 1 |
| Nesnow, S; Slaga, TJ; Triplett, LL | 1 |
| Fiorentini, KM; Fu, PP; Lu, AY; Wislocki, PG; Yang, SK | 1 |
| Iversen, OH; Iversen, UM | 2 |
| Glover, E; Palen, D; Poland, A | 1 |
| Fischer, SM; Mills, GD; Slaga, TJ | 1 |
| Buening, MK; Chang, RL; Conney, AH; Jerina, DM; Lehr, RE; Levin, W; Taylor, CW; Wood, AW; Yagi, H | 1 |
| Barbin, A; Bartsch, H; Croisy, A; Malaveille, C; Tomatis, L; Zajdela, F | 1 |
| Daub, GH; Iyer, RP; Lyga, JW; Secrist, JA; Slaga, TJ | 1 |
| Fischer, SM; Gleason, GL; Mills, GD; Slaga, TJ | 1 |
| Chao, WR; De Young, LM; Helmes, CT; Miller, V; Young, JM | 1 |
| Kakinuma, S; Takido, M; Yasukawa, K; Yu, SY | 1 |
| Abhyankar, S; Greenhalgh, DA; Hennings, H; Ngai, P; Schweizer, J; Strickland, JE; Sutter, C; Ueda, M; Yuspa, SH | 1 |
| Celli, G; Darwiche, N; De Luca, LM; Glick, AB; Tennenbaum, T; Yuspa, SH | 1 |
| Eckhardt, JN; Greenhalgh, DA; Roop, DR; Wang, XJ | 1 |
| Konoshima, T; Kozuka, M; Takasaki, M; Tokuda, H | 1 |
| Kim, TW; Smart, RC | 1 |
| Chada, K; Conney, AH; D'Armiento, J; Dalal, SS; DiColandrea, T; Huang, MT; Okada, Y | 1 |
| Davidson, C; Lecuyer, DW; McLean, JR; Plant, M; Truong, J | 1 |
| Blessing, M; Hogan, BL; King, LE; Nanney, LB | 1 |
| Owens, DM; Smart, RC; Spalding, JW; Tennant, RW | 1 |
| Conti, CJ; Gimenez-Conti, IB; Stern, MC | 1 |
| Jiang, H; Kato, R; Nishikawa, K; Yamamoto, S | 1 |
| Aliyakparova, LM; Anisimov, VN; Vorobtsova, IE | 1 |
| Clifford, A; Gilmour, S; Morgan, D; Soler, AP; Yuspa, SH | 1 |
| Conti, CJ; Robles, AI | 1 |
| Iwashima, A; Konoshima, T; Kozuka, M; Nishino, H; Takasaki, M; Tokuda, H; Yoneyama, K; Yoshida, S | 1 |
| Fürstenberger, G; Marks, F; Müller-Decker, K; Scholz, K | 1 |
| Fischer, SM; Maldve, RE | 1 |
| Kopp-Schneider, A; Portier, CJ | 2 |
| Fürstenberger, G; Kopp-Schneider, A | 1 |
| Dwivedi, C; Tabbert, J | 1 |
| Eppley, RM; Hines, FA; Lambert, LA | 1 |
| Hansen, LA; Tennant, R | 1 |
| Iwashima, A; Kasai, R; Konoshima, T; Kozuka, M; Nie, RL; Nishino, H; Takasaki, M; Tanaka, O; Tatsumoto, T; Tokuda, H | 1 |
| Hill, DL; Hosmer, CA; Riordan, JM; Rogers, TS; Shealy, YF; Wille, JW | 1 |
| Anderson, J; Barnett, T; Birt, DF; Pelling, JC | 1 |
| Chen, LC; De Luca, LM; Sly, L | 1 |
| Biozzi, G; Covelli, V; Doria, G; Mouton, D; Neveu, T; Pioli, C; Saran, A; Troiani, C | 1 |
| French, JE; Hansen, L; Libbus, BL; Mahler, J; Spalding, J; Tennant, RW; Tice, RR | 1 |
| Kopp-Schneider, A | 1 |
| Akihisa, T; Takido, M; Tamura, T; Yasukawa, K | 1 |
| Hansen, LA; Tennant, RW | 1 |
| Bowden, GT; Domann, FE; Finch, JS; Levy, JP | 1 |
| Gembardt, C; Kühborth, B; Mellert, W; Munk, R | 1 |
| Hori, Y; Kinoshita, N; Moon, DC; Nakayama, J; Terao, H; Urabe, A | 1 |
| Eckhardt, JN; Greenhalgh, DA; Roop, DR; Rothnagel, JA; Wang, XJ | 1 |
| Bagwe, AN; Bhisey, RA; Ramchandani, AG | 1 |
| Agarwal, R; Katiyar, SK; Mukhtar, H | 1 |
| Colapietro, AM; Goodell, AL; Smart, RC | 1 |
| Glick, AB; Hennings, H; Krsmanovic, LS; Lowry, DT; Sly, LM; Yuspa, SH | 1 |
| Inada, A; Iwashima, A; Konoshima, T; Kozuka, M; Nakanishi, T; Nishino, H; Tokuda, H | 1 |
| Elgjo, K; Iversen, OH; Paulsen, JE; Reichelt, KL | 1 |
| Mills, KJ; Reynolds, SH; Smart, RC | 1 |
| Kim, TW; Meyer, SA; Monteiro-Riviere, NA; Moser, GJ; Smart, RC | 1 |
| Bowden, GT; Chu, YW; Hendrix, MJ; Kittelson, J; Meade-Tollin, L; Powell, MB; Tsang, TC | 1 |
| Beland, PE; Fischer, WH; Lutz, WK | 1 |
| Elwell, MR; Momma, J; Spalding, JW; Tennant, RW | 1 |
| Möller, L; Toftgård, R; Zeisig, M | 1 |
| Anderson, LM; Diwan, BA; Rehm, S; Rice, JM | 1 |
| Balmain, A; Bradley, A; Donehower, LA; Kemp, CJ | 1 |
| Satomi, Y | 1 |
| Belanger, AJ; Glick, AB; Hennings, H; Tennenbaum, T; Weiner, AK; Yuspa, SH | 1 |
| Aldaz, CM; Conti, CJ; DiGiovanni, J; Slaga, TJ; Walker, SE | 1 |
| Bradley, A; Campo, MS; Chandrachud, L; Gaukroger, JM; Jarrett, WF | 1 |
| Barnett, T; Birt, DF; Dimitroff, K; Phan, A; Pinch, HJ | 1 |
| Dlugosz, AA; Hennings, H; Strickland, JE; Yuspa, SH | 1 |
| McCann, R; Mitchel, RE | 1 |
| Chen, LC; De Luca, LM; Jones, CS; Sly, L; Tarone, R | 1 |
| Bianchi, AB; Conti, CJ; Fischer, SM; Rinchik, EM; Robles, AI | 1 |
| Blumberg, PM; Krsmanovic, L; Szallasi, Z | 1 |
| Kim, SY; Lee, KJ; Lee, YH; Oh, SH; Park, KK | 1 |
| Jetten, AM; Owens, DM; Smart, RC; Zainal, TA | 1 |
| Das, UN; Ramesh, G | 1 |
| Conney, AH; Frenkel, K; Grunberger, D; Han, J; Huang, MT; Ma, W; Xie, JG; Yen, P | 1 |
| Beland, PE; Candrian, R; Fekete, T; Fischer, WH; Lutz, WK | 1 |
| Herlyn, M; Montone, KT; Nesbit, M; Satyamoorthy, K; Soballe, PW | 1 |
| Murakami, N; Nagatsu, A; Nishino, H; Sakakibara, J; Shirahashi, H; Tokuda, H | 1 |
| Aldaz, CM; Battalora, MS; Conti, CJ; DiGiovanni, J; Johnston, DA; Slaga, TJ | 1 |
| Barnett, T; Birt, DF; Copenhaver, J; Pour, PM | 1 |
| Anisimov, VN; Sheiko, EV | 1 |
| Huang, M; Tan, A; Wu, K | 1 |
| Long, BW; Oberyszyn, TM; Robertson, FM; Ross, MS; Tober, KL | 1 |
| Chen, LC; De Luca, LM; Huynh, M; Jones, CS; Tarone, R | 1 |
| Athar, M; Giri, U; Iqbal, M | 1 |
| Belury, MA; Bird, CE; Nickel, KP; Wu, Y | 1 |
| Agarwal, R; Ahmad, N; Mohan, RR; Mukhtar, H | 1 |
| Cano, A; Conti, CJ; Duran, H; Jorcano, JL; Larcher, F; Murillas, R; Quintanilla, M; Robles, AI | 1 |
| Balasubramanian, V; Kapadia, GJ; Konoshima, T; Koyama, J; Nishino, H; Tagahaya, K; Takasaki, M; Tokuda, H | 1 |
| Reiners, JJ; Singh, KP | 1 |
| Conti, CJ; La, E; Locniskar, MF; McCarthy, AC | 1 |
| Huang, MT; Inouye, M; Lou, YR; Lu, YP; Mirochnitchenko, OI; Newmark, HL; Yen, P | 1 |
| Goodrow, T; Klein-Szanto, AJ; Liu, SC; Morris, R; Zhang, SY | 1 |
| Budunova, IV; Carbajal, S; Kang, H; Slaga, TJ; Viaje, A | 1 |
| Dawson, MI; Dong, Z; Flavell, RA; Huang, C; Ma, WY; Rincon, M | 1 |
| Muller, HK; Qu, M; Woods, GM | 1 |
| Inada, A; Nakanishi, T; Nishino, H; Sharma, OP; Tokuda, H | 1 |
| Becker, K; Gregel, CM; Kaina, B | 1 |
| Coulter, K; Morris, RJ; Steinberg, SR; Tryson, K | 1 |
| Fischer, SM; Li-Stiles, B; Lo, HH | 1 |
| Conti, CJ; Reiners, JJ; Singh, KP; Yoon, HL | 1 |
| Haseman, JK; Tennant, RW; Trempus, CS | 1 |
| Foley, JF; Kim, TW; Maronpot, RR; Porter, KL; Smart, RC | 1 |
| Binder, RL; Conti, CJ; Gallagher, PM; Johnson, GR; Smith, BJ; Stockman, SL; Sundberg, JP | 1 |
| Aldaz, CM; Bednarek, AK; Chu, Y; Slaga, TJ | 1 |
| Travis, CC; Watanabe, KH | 1 |
| Budunova, I; Coghlan, L; Conti, CJ; DiGiovanni, J; Fischer, SM; Gimenez-Conti, IB; Slaga, TJ; Stern, MC | 1 |
| Darwiche, N; De Luca, LM; Gartsbein, M; Hansen, L; Hennings, H; Lowry, D; Morgan, DL; Tennenbaum, T; Yuspa, SH | 1 |
| Fürstenberger, G; Lehmann, WD; Löschke, M; Marks, F; Müller-Decker, K; Scholz, K | 1 |
| Brinkley, BR; Greenhalgh, DA; He, D; Jiang, A; Medina, D; Roop, DR; Wang, XJ; Zhong, L | 1 |
| Bolontrade, M; Conti, CJ; Jorcano, JL; Larcher, F; Murillas, R | 1 |
| Duc, NM; Kasai, R; Konoshima, T; Nishino, H; Takasaki, M; Tokuda, H; Yamasaki, K | 1 |
| Gilmour, SK; Smith, MK; Trempus, CS | 1 |
| Binder, RL; Conti, CJ; Gallagher, PM; Johnson, GR; Stockman, SL; Sundberg, JP | 1 |
| Fischer, WH; Lutz, WK | 1 |
| Kiyosawa, S; Konishi, T; Konoshima, T; Takasaki, M; Tokuda, H | 1 |
| Hansen, LA; Malarkey, DE; Rosenberg, M; Tennant, RW; Wilkinson, JE; Woychik, RE | 1 |
| Brinkley, BR; Greenhalgh, DA; He, D; Jiang, A; Roop, DR; Wang, XJ; Zhong, L | 1 |
| Boorman, GA; Bruccoleri, A; Chen, GS; Foley, JF; Germolec, DR; Humble, MC; Luster, MI; Simeonova, PP; Spalding, J; Yoshida, T; Yu, HS | 1 |
| Agarwal, MK; Athar, M; Giri, U; Iqbal, M; Khan, S | 1 |
| Deng, C; Fernandez-Salas, E; Hennings, H; Mirosh, E; Morgan, DL; Shalizi, A; Stanulis, E; Weinberg, WC; Yuspa, SH | 1 |
| Fischer, SM; La, E; Locniskar, MF; Muga, SJ | 1 |
| Ahmad, N; Balasubramanian, S; Mukhtar, H | 1 |
| Ageta, H; Arai, Y; Konoshima, T; Masuda, K; Shiojima, K; Takasaki, M; Tokuda, H | 1 |
| Konoshima, T; Nishino, H; Takasaki, M; Tokuda, H | 1 |
| Hatano, T; Ito, H; Konoshima, T; Kozuka, M; Miyake, M; Mori, K; Mukainaka, T; Nishino, H; Nishitani, E; Okuda, T; Takasaki, M; Tokuda, H; Yoshida, T | 1 |
| Gurley, KE; Kemp, CJ; Philipp, J; Seidel, K; Vo, K | 1 |
| Chang, RL; Conney, AH; Cui, XX; Gwynne, M; Huang, MT; Jerina, DM; Lou, YR; Lu, YP; Merkler, KA; Murthy, B; Wei, SJ; Xie, JG | 1 |
| Bowden, GT; Broome Powell, M; Gause, PR; Gregus, J; Hyman, P; Lluria-Prevatt, M; Nagle, R | 1 |
| Owens, DM; Smart, RC; Wei, S | 1 |
| Biozzi, G; Bouthillier, Y; Covelli, V; Doria, G; Mouton, D; Pazzaglia, S; Pioli, C; Rebessi, S; Saran, A | 1 |
| Greenhalgh, DA; Liefer, KM; Roop, DR; Wang, XJ | 1 |
| Ahrens, H; Dreckschmidt, NE; Oberley, TD; Reddig, PJ; Simsiman, R; Tseng, CP; Verma, AK; Zou, J | 1 |
| Battalora, MS; Bishop, WR; Doll, RJ; Haseman, JK; Mahler, JF; Njoroge, FG; Tennant, RW; Trempus, CS | 1 |
| Cros, MP; Omori, Y; Yamakage, K; Yamasaki, H; Zaidan-Dagli, ML | 1 |
| Duc, NM; Ichiishi, E; Kasai, R; Konoshima, T; Murakami, T; Nishino, H; Takasaki, M; Tokuda, H; Yamasaki, K | 1 |
| Lambert, PF; Liem, A; Miller, JA; Song, S | 1 |
| Morris, RJ; Tryson, KA; Wu, KQ | 1 |
| Bourguignon, SE; Dreckschmidt, NE; Oberley, TD; Reddig, PJ; Verma, AK; Zou, J | 1 |
| Coghlan, LG; Conti, CJ; DiGiovanni, J; Fischer, SM; Gimenez-Conti, I; Kleiner, HE; Rundhaug, JE; Slaga, TJ | 1 |
| Chun, KS; Keum, YS; Kwon, H; Lee, JM; Lee, SK; Park, JH; Park, KK; Surh, YJ | 1 |
| Furukawa, H; Ishikawa, T; Ito, C; Itoigawa, M; Mukainaka, T; Nishino, H; Tan, HT; Tokuda, H; Yang Mou, X | 1 |
| Furukawa, H; Ito, C; Iwase, Y; Ju-ichi, M; Kawaii, S; Mou, XY; Nishino, H; Takayasu, J; Takemura, Y; Tokuda, H; Yano, M | 1 |
| Affara, NI; Gali-Muhtasib, HU | 1 |
| Atit, RP; Mitchell, K; Nguyen, L; Ratner, N; Warshawsky, D | 1 |
| Brinkley, BR; Go, C; He, W; Huang, J; Li, P; Wang, XJ; Zhong, L | 1 |
| Gaiotti, D; Hansen, L; Michael, E; Nees, M; Woodworth, CD | 1 |
| Blasco, MA; Flores, JM; González-Suárez, E; Samper, E | 1 |
| Beltrán, L; Bol, D; Carbajal, S; Chan, K; DiGiovanni, J; Jorcano, J; Kiguchi, K; Moats, S | 1 |
| Ishida, J; Konoshima, T; Kozuka, M; Lee, KH; Nagai, M; Nishino, H; Okuda, M; Sakurai, N; Tokuda, H; Wang, H; Yang Mou, X | 1 |
| Murakami, A; Nakamura, Y; Ohigashi, H; Ohto, Y; Tanaka, T; Torikai, K | 1 |
| Kang, JK; Kim, DH; Kim, HS; Kim, JH; Lee, JE; Lee, SH; Seo, JS | 1 |
| Donehower, LA; Greenhalgh, DA; Roop, DR; Wang, XJ | 1 |
| Iwamoto, M; Matsunaga, S; Minami, T; Nishino, H; Ohtsu, H; Tanaka, R; Tokuda, H; Yoshitake, A | 1 |
| Colombo, D; Compostella, F; Kuchide, M; Nishino, H; Ronchetti, F; Scala, A; Tokuda, H; Toma, L | 1 |
| Agadir, A; Bai, L; Chandraratna, RA; Chao, W; Chen, G; Dawson, MI; Dousman, L; Gu, J; Hill, DL; Hobbs, PD; Jong, L; Merchant, JL; Park, JH; Shroot, B; Thacher, SM; Toll, L; Verma, AK; Waleh, N; Zhang, X | 1 |
| Furukawa, H; Ito, C; Iwase, Y; Ju-ichi, M; Kuchide, M; Mukainaka, T; Nishino, H; Takemura, Y; Tokuda, H; Yano, M | 1 |
| Biozzi, G; Covelli, V; Mancuso, M; Pazzaglia, S; Primerano, B; Rebessi, S; Saran, A | 1 |
| Klein-Szanto, A; Zhang, S | 1 |
| Goerttler, K; Hesse, B; Löhrke, H | 1 |
| Battalora, MS; Bortner, CD; Cape, JE; Lee, BM; Morris, RJ; Spalding, JW; Szczesniak, CJ; Tennant, RW; Trempus, CS | 1 |
| Beissert, S; Kupper, TS; Mayer, C; Rossiter, H; Schön, MP; Tschachler, E; Wienrich, BG | 1 |
| Alhonen, L; Jänne, J; Parkkinen, JJ; Pietilä, M | 1 |
| Bode, AM; Chen, N; Dong, Z; Flavell, RA; Ma, WY; Nomura, M; She, QB; Wang, L | 1 |
| Blasco, MA; Flores, JM; González-Suárez, E; Jorcano, JL; Martín-Caballero, J; Ramírez, A; Samper, E | 1 |
| Ben-Shaul, V; Bergman, M; Boorman, G; Dunson, DB; Goldsworthy, TL; Grossman, S; Lomnitski, L; Nyska, A; Spalding, J | 1 |
| Furukawa, H; Ito, C; Itoigawa, M; Kuchide, M; Nishino, H; Tan, HT; Tokuda, H | 1 |
| Owens, DM; Watt, FM | 1 |
| Athar, M; Sharma, N; Trikha, P | 1 |
| Matsunaga, S; Minami, T; Nishino, H; Tanaka, R; Terada, Y; Tokuda, H; Tsujimoto, K; Yoshitake, A | 1 |
| Arntzen, CJ; Ganesh, P; Gutterman, JU; Hanausek, M; Slaga, TJ; Walaszek, Z | 1 |
| Beason, CW; Dick, EJ; DiGiovanni, J; Dusch, SJ; Jauchem, JR; Mahajan, K; Mason, PA; Merritt, JH; Murphy, MR; Ryan, KL; Shields, BA; Walters, TJ | 1 |
| Furukawa, H; Ichiishi, E; Ito, C; Iwase, Y; Ju-ichi, M; Mukainaka, T; Nishino, H; Takemura, Y; Tokuda, H; Yano, M | 1 |
| Furukawa, H; Ito, C; Itoigawa, M; Nishino, H; Okuda, M; Tan, HT; Tokuda, H | 1 |
| Fujiwara, O; Imaida, K; Kato, K; Kuzutani, K; Ogiso, T; Shirai, T; Wang, J | 1 |
| Conti, CJ; Gómez-Casero, E; Jorcano, JL; Larcher, F; Navarro, M; Paramio, JM; Rodríguez-Puebla, ML | 1 |
| Angel, JM; Caballero, M; DiGiovanni, J | 1 |
| Blanchard, KT; Cannon, RE; Honchel, R; Rosenzweig, BA; Sistare, FD; Stoll, RE; Thompson, KL | 1 |
| Covelli, V; Dragani, TA; Galbiati, F; Mancuso, MT; Manenti, G; Pazzaglia, S; Peissel, B; Rebessi, S; Saran, A; Spinola, M; Zaffaroni, D; Zanesi, N | 1 |
| Brantner, A; Chakraborty, A; Konoshima, T; Kuchide, M; Mukainaka, T; Nishino, H; Nobukuni, Y; Tokuda, H | 1 |
| Bode, AM; Chen, N; Dong, Z; Flavell, RA; She, QB | 1 |
| Guo, Y; O'Brien, TG; Pegg, AE; Sawicki, JA; Shantz, LM | 1 |
| Arisawa, M; Kurosaki, F; Mukainaka, T; Nakamura, ES; Nishino, H; Okuda, M; Pastore, F; Takayasu, J; Tokuda, H | 1 |
| Akunda, J; Dunson, DB; Langenbach, R; Lee, CA; Loftin, CD; Morham, SG; Rogan, EG; Sessoms, A; Smart, RC; Spalding, J; Tiano, HF | 1 |
| Angel, P; Breitenbach, U; Dittrich, BT; Gebhardt, C; Richter, KH; Tuckermann, JP | 1 |
| Goerttler, K; Loehrke, H; Schweizer, J | 1 |
| DiGiovanni, J; Gleason, GL; Harvey, RG; Slaga, TJ; Sukumaran, KB | 1 |
| Melchionne, S; Segal, A; Seidman, I; Smith, AC; Tseng, SS; Van Duuren, BL | 1 |
| Bracken, WM; Gleason, GL; Hennings, H; Slaga, TJ; Weeks, CE | 1 |
| Boukamp, HK; Worst, PK | 1 |
| Armuth, V; Berenblum, I | 1 |
| Boutwell, RK; Mufson, RA; Simsiman, RC | 1 |
| Boutwell, RK; Fischer, SM; Gleason, GL; Mufson, RA; Slaga, TJ; Verma, AK | 1 |
| Goldschmidt, BM; Loewengart, G; Melchionne, S; Roth, D; Seldman, I; Smith, AC; Van Duuren, BL | 1 |
| Marks, F; Schweizer, J | 1 |
| Gleason, GL; Hardin, L; Slaga, TJ | 1 |
| Bracken, WM; Conney, AH; Dresner, S; Jerina, DM; Levin, W; Slaga, TJ; Yagi, H | 1 |
| Maté, U; Melchionne, S; Segal, A; Seidman, I; Smith, A; Solomon, JJ; Van Duuren, BL | 1 |
| Chang, RL; Conney, AH; Jerina, DM; Lehr, RE; Levin, W; Thakker, DR; Wood, AW | 1 |
| Hecht, SS; Hirota, N; Hoffman, D | 1 |
| Bracken, WJ; Conney, AH; Gleason, G; Jerina, DM; Levin, W; Slaga, TJ; Yagi, H | 1 |
| Boutwell, RK; Rice, HM; Shapas, BG; Verma, AK | 1 |
| Segal, A; Van Duuren, BL | 1 |
| Albert, RE; Burns, FJ; Sivak, A; Vanderlaan, M | 1 |
| Goerttler, L; Loehrke, H | 1 |
| Scribner, JD; Slaga, TJ; Viaje, A | 1 |
| Goerttler, K; Loehrke, H | 2 |
| Chang, RL; Conney, AH; Jerina, DM; Levin, W; Slaga, TJ; Wood, AW; Yagi, H | 1 |
| Berry, DL; Bracken, WM; Fischer, SM; Leclerc, SM; Miller, DR; Slaga, TJ; Viaje, A | 1 |
| Bracken, WM; Conney, AH; Jerina, DM; Levin, W; Slaga, TJ; Viaje, A; Yagi, H | 1 |
| Chouroulinkov, I; Gentil, A; Grover, PL; Sims, P | 1 |
| Boutwell, RK; Bowden, GT; Slaga, TJ | 1 |
| Glick, A; Greenhalgh, D; Hennings, H; Morgan, D; Welty, D; Yuspa, SH | 1 |
| Bianchi, AB; Conti, CJ; Fischer, SM; Gimenez-Conti, IB; Reiners, JJ; Slaga, TJ | 1 |
| Ballestín, C; Bauluz, C; Conti, CJ; Díaz-Guerra, M; Jorcano, JL; Larcher, F; Quintanilla, M | 1 |
| Fuchs, E; Hutton, ME; Vassar, R | 1 |
| Hasegawa, T; Iwashima, A; Kitano, H; Murakoshi, M; Nishino, H; Okabe, H; Okuzumi, J; Satomi, Y; Takayasu, J; Tokuda, H | 1 |
| Chang, R; Conney, AH; Ferraro, T; Ho, CT; Huang, MT; Ma, W; Reuhl, KR; Wang, ZY; Yang, CS | 1 |
| Pashko, LL; Schwartz, AG | 1 |
| Pelling, JC; Strawhecker, JM | 1 |
| Chen, LC; De Luca, LM; Jones, CS; Sly, L | 1 |
| Islam, TC; Toftgård, R | 1 |
| Dwivedi, C; Engineer, FN; Jarvis, D; Rohlfs, S | 1 |
| Burnett, R; Goddard, M; Lecuyer, DW; McLean, JR; Mitchel, RE; Stuchly, MA | 1 |
| Alhonen, L; Halmekytö, M; Jänne, J; Syrjänen, K | 1 |
| Barnett, T; Birt, DF; Enkvetchakul, B; Geisler, V; Liotta, DC; Menaldino, D; Merrill, AH | 1 |
| Hennings, H; Strickland, JE; Ueda, M; Yuspa, SH | 1 |
| Boone, CW; Kelloff, GJ; Steele, VE | 1 |
| Gali, HU; Johnson, JM; Klish, DS; Perchellet, EM; Perchellet, JP | 1 |
| Bocckino, SB; Burns, DJ; Loomis, CR; Mills, KJ; Smart, RC | 1 |
| Kuratko, CN; Lawlis, RS; Pence, BC; Richard, BC | 1 |
| Bonham, K; Bowden, GT; Krieg, P; Ostrowski, LE | 1 |
| Andrews, K; Bowden, GT; Finch, J; Fürstenberger, G; Krieg, P; Ootsuyama, A; Slaga, T; Tanooka, H | 1 |
| Clausen, OP; Heyden, A; Huitfeldt, HS; Roop, D; Thrane, EV; Yuspa, SH | 1 |
| Schweizer, J; Strickland, JE; Sutter, C; Welty, DJ; Winter, H; Yuspa, SH | 1 |
| Gensler, HL; Welch, K | 1 |
| Andringa, A; Barkley, W; LaDow, K; Miller, ML; Warshawsky, D | 1 |
| Cantu, AR; Reiners, JJ; Rupp, T; Thai, G | 1 |
| Agarwal, R; Athar, M; Bickers, DR; Lloyd, JR; Mukhtar, H; Wang, ZY | 1 |
| Cappel, RE; Gilbert, HF; Kodari, E; Reiners, JJ | 1 |
| Kimura, T; Konoshima, T; Kozuka, M; Tokuda, H | 1 |
| Gernold, M; Gschwendt, M; Leibersperger, H; Marks, F | 1 |
| Aldaz, CM; Bianchi, A; Chen, A; Conti, CJ; DiGiovanni, J; Walker, SB | 1 |
| Bechtel, D; Belury, MA; Fischer, SM; Lee, ML; Leyton, J; Locniskar, M; Slaga, TJ | 1 |
| Barnett, T; Birt, DF; Dimitroff, K; Pelling, JC; White, LT | 1 |
| Byus, CV; Gonzalez, GG | 1 |
| Hirota, M; Irie, R; Jisaka, M; Koshimizu, K; Murakami, A; Ohigashi, H | 1 |
| Blumenson, LE; East, CJ; Kulesz-Martin, MF; Manly, KF; Siracký, J | 1 |
| Aldaz, CM; Bianchi, AB; Conti, CJ; Navone, NM | 1 |
| Anisimov, VN; Loktionov, AS; Popovich, IG; Zabezhinskiĭ, MA | 1 |
| Koza, RA; Megosh, LC; O'Brien, TG; Palmieri, M | 1 |
| Greenhalgh, DG; Hennings, H; Robinson, VA; Welty, DJ; Yuspa, SH | 1 |
| Lewbart, ML; Pashko, LL; Schwartz, AG | 1 |
| Devor, DE; Henneman, JR; Keefer, LK; Logsdon, DL; Rice, JM; Streeter, AJ; Ward, JM | 1 |
| Birt, DF; Bresnick, E; Tye, L; Wei, H | 1 |
| Balaschak, M; Hennings, H; Shores, R; Yuspa, SH | 1 |
| Aizu, E; Kato, R; Nakadate, T; Yamamoto, S | 2 |
| Baker, RS; Steinel, HH | 2 |
| Fischer, SM; Patamalai, B; Patrick, KE; Slaga, TJ | 1 |
| Bhisey, RA; Veturkar, PL | 1 |
| Belman, S; Bosland, MC; Estensen, RD; Savarese, K; Sellakumar, A | 1 |
| Fialkow, PJ; Reddy, AL | 5 |
| Hashiba, H; Hashimoto, Y; Kuroki, T; Nose, K; Tajima, O | 1 |
| Dietel, M; Hilz, H; Ludwig, A; Müller, K; Schäfer, G | 1 |
| Binder, RL; Cunniff, JJ; Maurer, JK; Newmann, EA; Sundberg, JP | 1 |
| Matsumoto, T; Tokuda, H | 1 |
| Burns, FJ | 2 |
| Perchellet, JP; Satyamoorthy, K | 1 |
| Fürstenberger, G; Marks, F | 1 |
| Beavis, AJ; Conney, AH; Gilmour, SK; Hietala, OA; Huang, MT; Laskin, JD; O'Brien, TG; Robertson, FM | 1 |
| Hansen, LA; Monteiro-Riviere, NA; Smart, RC | 1 |
| Roop, DR; Toftgard, R; Yuspa, SH | 2 |
| Hennings, H; Mitchell, P; Shores, R; Spangler, EF; Yuspa, SH | 1 |
| Parkinson, EK | 1 |
| Aglow, E; Gilmour, SK; O'Brien, TG | 1 |
| Ernst, SM; Johnson, JA; Nairn, RS; Pelling, JC; Slaga, TJ; Strawhecker, JM | 1 |
| Cheng, CK; Krieg, TM; Mehrel, T; Roop, DR; Yuspa, SH | 1 |
| Aldaz, CM; Chesner, J; Conti, CJ; Larcher, F; Roop, DR; Slaga, TJ; Trono, D; Whitehead, T | 1 |
| Aldaz, CM; Conti, CJ | 1 |
| Birt, DF; Choi, B; Pelling, JC; White, LT | 1 |
| Aldaz, CM; Conti, CJ; Miller, DR; Rotstein, J; Slaga, TJ; Viaje, A | 1 |
| Cantu, AR; Colby, A; Pavone, A; Reiners, JJ; Rupp, T | 1 |
| Amtmann, E; Fürstenberger, G; Marks, F; Sauer, G | 1 |
| Becher, H; Chouroulinkov, I; Day, NE; Lasne, C; Lowy, R; Wahrendorf, J; Yamasaki, H | 1 |
| Conti, CJ; DiGiovanni, J; Ewing, MW; Phillips, JL; Slaga, TJ | 1 |
| Birt, DF; Pelling, JC; Schweickert, L; Tibbels, MG | 1 |
| Furukawa, F; Hasegawa, R; Hayashi, Y; Imaida, K; Sato, H; Takahashi, M; Toyoda, K | 1 |
| Gill, TJ; Shinozuka, H; Yokota, K | 1 |
| Dlugosz, AA; Dzubow, L; Gilmour, SK; Hietala, O; O'Brien, TG; O'Donnell, K | 1 |
| Athar, M; Bickers, DR; Lloyd, JR; Mukhtar, H | 1 |
| Blumberg, PM; Hennings, H; Sharkey, NA; Yuspa, SH | 1 |
| Kim, YS; Park, KK | 1 |
| Fairman, DK; Lewbart, ML; Pashko, LL; Polansky, M; Schwartz, AG | 1 |
| Hashiba, H; Hosoi, J; Karasawa, M; Kuroki, T; Nose, K; Yamada, S | 1 |
| Konoshima, T; Kozuka, M; Tanabe, M; Tokuda, H | 1 |
| Bonham, K; Bowden, GT; Cress, AE; Embry, T; Gibson, D; Jaffe, DR; Roberts, RA | 1 |
| Bowden, GT; Jaffe, DR | 2 |
| Baldwin, JK; Butler, AP; Cameron, GS; Fischer, SM; Jasheway, DW; Klann, RC; Patrick, KE | 1 |
| Greenhalgh, DA; Harper, JR; Lacal, JC; Reynolds, SH; Strickland, JE; Yuspa, SH | 1 |
| Chiba, M; Klein-Szanto, AJ; Maley, MA | 1 |
| Digiovanni, DM; Fries, JW; Klein-Szanto, AJ; O'Connell, JF; Slaga, TJ | 2 |
| Hennings, H; Kilkenny, A; Lichti, U; Michael, D; Morgan, D; Spangler, EF; Yuspa, SH | 1 |
| Cabral, JR; Galendo, D; Hollstein, M; Martel, N; Tomatis, L; Yamasaki, H | 1 |
| Fürstenberger, G; Gross, M; Marks, F | 1 |
| Balmain, A; Brown, K; Kerr, IB; Quintanilla, M; Ramsden, M; Young, S | 1 |
| Kato, R; Nakadate, T; Yamamoto, S | 1 |
| Ali, M; Duvick, L; Verma, AK | 1 |
| Gragtmans, NJ; Jevcak, JJ; Mitchel, RE; Morrison, DP | 1 |
| Fujiki, H; Nitta, K; Takeuchi, M | 1 |
| Slaga, TJ | 1 |
| Anderson, LM; Rice, JM | 1 |
| Caldwell, M; Fialkow, PJ; Reddy, AL | 2 |
| Aldaz, CM; Conti, CJ; Klein-Szanto, AJ; Slaga, TJ | 1 |
| Conti, CJ; DiGiovanni, J; Kruszewski, FH | 1 |
| Scherneck, S; Wunderlich, V | 1 |
| Fischer, SM; Neades, R; Pelling, JC; Schweickert, L; Strawhecker, J | 1 |
| Brown, CC; Chu, KC; Tan, WY; Tarone, RE | 1 |
| Balaschak, M; Greenhalgh, DA; Hennings, H; Koceva-Chyla, A; Restrepo, C; Strickland, JE; Yuspa, SH | 1 |
| Hibasami, H; Maekawa, S; Nakashima, K; Sakurai, M; Tsukada, T | 1 |
| Gragtmans, NJ; Mitchel, RE; Morrison, DP | 1 |
| Crysup, SE; DiGiovanni, J; Ewing, MW; Phillips, JL; Slaga, TJ | 1 |
| Chao, WR; Dawson, MI | 1 |
| Chenicek, KJ; DiGiovanni, J; Kruszewski, FH | 2 |
| Chouroulinkov, I; Grover, P; Lasne, C; Phillips, D | 1 |
| Conti, CJ; DiGiovanni, J; Ewing, MW; Kruszewski, FH; Slaga, TJ | 1 |
| Bowden, GT; Breathnach, R; Finch, J; Krieg, P; Matrisian, L; O'Connell, JF; Ostrowski, LE; Patskan, G; Phillips, J; Slaga, TJ | 1 |
| Bhisey, RA; Borges, A; Jeyapaul, J; Veturkar, PL | 1 |
| Holmes, M; Madara, T; O'Brien, TG; Pyle, JA | 1 |
| Bowden, GT; Gensler, HL; Moriguchi, S; Watson, RR | 1 |
| Kuwano, H; Matsufuji, H; Mori, M; Sugimachi, K; Ueo, H | 1 |
| Bowden, GT; Breathnach, R; Briand, JP; Fürstenberger, G; Krieg, P; Leroy, P; Matrisian, LM | 1 |
| Kumar, S; Mehrotra, NK; Shukla, Y | 1 |
| Bowden, GT; Jaffe, DR; Williamson, JF | 1 |
| Baxter, CS; Miller, ML | 1 |
| Bull, RJ; Laurie, RD; Robinson, M | 1 |
| Bergman, H; Nesnow, S; Slaga, TJ | 1 |
| Ebbesen, P | 1 |
| Creasia, D; Kripke, ML; Strickland, PT | 1 |
| Diwan, BA; Henneman, J; Ward, JM; Wenk, ML | 1 |
| Hennings, H; Yuspa, SH | 1 |
| Hashimura, T; Yoshida, O | 1 |
| Boutwell, RK; Cleaveland, JS; Ordman, AB | 1 |
| Boutwell, RK; Simsiman, RC; Takigawa, M | 1 |
| Aalfs, KK; Cantor, J; Coombs, MM; Decina, PC; DiGiovanni, J; Prichett, WP | 1 |
| Marian, B; Mazzucco, K | 1 |
| Barnhart, KM; Bowden, GT | 1 |
| Argyris, TS | 1 |
12 review(s) available for tetradecanoylphorbol acetate and Papilloma
| Article | Year |
|---|---|
Non-melanoma skin cancer in mouse and man.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Disease Models, Animal; Disease Progression; Genes, p53; Genes, ras; Humans; Melanoma; Mice; Mutation; Neoplasm Invasiveness; Neoplastic Stem Cells; Papilloma; Risk Assessment; Skin; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 2013 |
Molecular and cellular basis for tumor promotion in mouse skin.
Topics: Animals; Calcium; Cell Division; Cell Transformation, Neoplastic; Mice; Oncogenes; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
The paradigm of two-stage carcinogenesis: a critical attitude.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Drug Interactions; Hyperplasia; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Nude; Models, Biological; Neoplasms; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Urethane | 1984 |
Upregulation of E2F transcription factors in chemically induced mouse skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carrier Proteins; Cell Cycle Proteins; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; E2F3 Transcription Factor; E2F4 Transcription Factor; E2F5 Transcription Factor; Female; Mice; Papilloma; Retinoblastoma-Binding Protein 1; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor DP1; Transcription Factors; Up-Regulation | 1999 |
Natural history of intraepithelial neoplasia in humans with implications for cancer chemoprevention strategy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinoma; Epithelium; Humans; Papilloma; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Differential gene expression during tumor promotion and progression in the mouse skin model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA; Gene Expression Regulation, Neoplastic; Matrix Metalloproteinase 3; Metalloendopeptidases; Methylnitronitrosoguanidine; Mice; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms, Multiple Primary; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ubiquitins | 1991 |
Promotion and progression in carcinogenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Disease Models, Animal; Mice; Papilloma; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
The conversion stage of skin carcinogenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Mice; Models, Biological; Papilloma; Phorbol Esters; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Defective responses of transformed keratinocytes to terminal differentiation stimuli. Their role in epidermal tumour promotion by phorbol esters and by deep skin wounding.
Topics: Animals; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Epidermis; In Vitro Techniques; Keratins; Mice; Mitosis; Oncogenes; Papilloma; Peptides; Phenotype; Phorbols; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factors | 1985 |
The premalignant nature of mouse skin papillomas: histopathologic, cytogenetic, and biochemical evidence.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Disorders; Karyotyping; Keratins; Mice; Papilloma; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Development of murine skin neoplasia studied with enzymes used as cell markers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinoma; Fibrosarcoma; Mice; Papilloma; Phosphoglycerate Kinase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
SENCAR mouse skin tumorigenesis model versus other strains and stocks of mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Disease Models, Animal; Drug Evaluation, Preclinical; Methylnitronitrosoguanidine; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1986 |
513 other study(ies) available for tetradecanoylphorbol acetate and Papilloma
| Article | Year |
|---|---|
IL-13Rα1 Suppresses Tumor Progression in Two-Stage Skin Carcinogenesis Model by Regulating Regulatory T Cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Interleukin-13; Interleukin-13 Receptor alpha1 Subunit; Mice; Mice, Knockout; Papilloma; Skin Neoplasms; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate | 2022 |
Isolation of cancer stem cells from skin squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Carcinoma, Squamous Cell; Disease Models, Animal; Humans; Mice; Neoplastic Stem Cells; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2022 |
DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; CCAAT-Enhancer-Binding Protein-beta; Cell Cycle Checkpoints; Cell Proliferation; Cellular Senescence; DNA Methylation; Epigenesis, Genetic; Female; Fibroblasts; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Interleukin-1alpha; Membrane Proteins; Mice; Microscopy, Fluorescence; Papilloma; Phenotype; Secretory Pathway; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2021 |
PAD2 overexpression in transgenic mice augments malignancy and tumor-associated inflammation in chemically initiated skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Male; Mice; Mice, Transgenic; Papilloma; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2017 |
Dendrimer conjugated estramustine nanocrystalline 'Dendot': An effective inhibitor of DMBA-TPA induced papilloma formation in mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Apoptosis; Carcinogens; Cell Proliferation; Dendrimers; Estramustine; Female; Intestines; Kidney; Liver; Mice; Nanoparticles; Papilloma; Skin Neoplasms; Stomach; Tetradecanoylphorbol Acetate | 2017 |
The Role of Fibroblast Growth Factor-Binding Protein 1 in Skin Carcinogenesis and Inflammation.
Topics: Animals; Bone Marrow; Bone Marrow Transplantation; Carcinogenesis; Carcinogens; Carrier Proteins; Female; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation; Water Loss, Insensible; Wound Healing | 2018 |
Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Bone Morphogenetic Protein 5; Cell Movement; Cell Plasticity; Cell Transformation, Neoplastic; Coculture Techniques; Epithelial Cells; Female; Hair Follicle; HMGB1 Protein; Keratinocytes; Keratins; Male; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Papilloma; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2018 |
New 6-amino-6-deoxy-glycoglycerolipids derived from 2-O-β-D-glucopyranosylglycerol: insights into the structure-activity relationship of glycoglycerolipids as anti-tumor promoters.
Topics: Animals; Antigens, Viral; Antineoplastic Agents; Drug Screening Assays, Antitumor; Female; Glucosides; Glycolipids; Humans; Mice; Molecular Structure; Nasopharyngeal Neoplasms; Nitrogen; Oxygen; Papilloma; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2013 |
Effects of two disiloxanes ALIS-409 and ALIS-421 on chemoprevention in model experiments.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Breast Neoplasms; Carcinogens; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Female; Fibroblasts; Humans; Lung; Mice; Mice, Inbred ICR; Morpholines; Papilloma; Piperazines; Siloxanes; Skin Neoplasms; Stromal Cells; Tetradecanoylphorbol Acetate | 2013 |
Chemoprevention of skin cancer: effect of Lawsonia inermis L. (Henna) leaf powder and its pigment artifact, lawsone in the Epstein- Barr virus early antigen activation assay and in two-stage mouse skin carcinogenesis models.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Administration, Oral; Animals; Antigens, Viral; Antineoplastic Agents, Phytogenic; B-Lymphocytes; Carcinogenesis; Cell Line, Tumor; Female; Herpesvirus 4, Human; Humans; Lawsonia Plant; Male; Naphthoquinones; Papilloma; Plant Extracts; Plant Leaves; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2013 |
A role for NF-κB activity in skin hyperplasia and the development of keratoacanthomata in mice.
Topics: Amino Acid Substitution; Animals; Cell Proliferation; Hyperplasia; Keratoacanthoma; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Papilloma; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor RelA | 2013 |
PD-1 blockage delays murine squamous cell carcinoma development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies, Monoclonal; Carcinoma, Squamous Cell; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytokines; Female; Flow Cytometry; Immunoenzyme Techniques; Interferon-gamma; Mice; Mice, Inbred BALB C; Papilloma; Programmed Cell Death 1 Receptor; Tetradecanoylphorbol Acetate | 2014 |
Genome-wide screening of aberrant DNA methylation which associated with gene expression in mouse skin cancers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Azacitidine; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred C57BL; Papilloma; Promoter Regions, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-2 | 2015 |
A derivative of chrysin suppresses two-stage skin carcinogenesis by inhibiting mitogen- and stress-activated kinase 1.
Topics: Animals; Anticarcinogenic Agents; Cell Cycle; Cell Proliferation; Cell Transformation, Neoplastic; Flavones; Flavonoids; Histones; Male; Mice; p38 Mitogen-Activated Protein Kinases; Papilloma; Phenethylamines; Phosphorylation; Protein Structure, Tertiary; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
Metformin inhibits skin tumor promotion in overweight and obese mice.
Topics: Adenylate Kinase; Adiponectin; Animals; Body Weight; Carcinogenesis; Carcinoma, Squamous Cell; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Insulin; Insulin-Like Growth Factor I; Leptin; Mechanistic Target of Rapamycin Complex 1; Metformin; Mice; Mice, Obese; Multiprotein Complexes; Neoplasms, Experimental; Obesity; Overweight; Papilloma; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Skin Neoplasms; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases | 2014 |
Mast cells are dispensable for normal and activin-promoted wound healing and skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Activins; Animals; Carcinogens; Carcinoma, Squamous Cell; Chemotaxis; Female; Humans; Injections, Intralesional; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neovascularization, Pathologic; Neutrophil Infiltration; Papilloma; Proto-Oncogene Proteins c-kit; Recombinant Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Wound Healing | 2013 |
Transformation by Hras(G12V) is consistently associated with mutant allele copy gains and is reversed by farnesyl transferase inhibition.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line, Tumor; Enzyme Inhibitors; Farnesyltranstransferase; Gene Dosage; Gene Knock-In Techniques; Genes, ras; Humans; Mice, Mutant Strains; Mutation; Papilloma; Piperidines; Pyridines; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cytokines; Dendritic Cells; Female; Gene Expression Regulation; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Lymphocyte Culture Test, Mixed; Male; Mice; Mice, Knockout; Papilloma; Signal Transduction; Skin Neoplasms; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate; Th1-Th2 Balance | 2014 |
IL-13 but not IL-4 signaling via IL-4Rα protects mice from papilloma formation during DMBA/TPA two-step skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cytokines; Interleukin-13 Receptor alpha1 Subunit; Methylcholanthrene; Mice; Mice, Inbred BALB C; Mice, Knockout; Papilloma; Receptors, Cell Surface; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2013 |
Does increase in DNA repair allow "tolerance-to-insult" in chemical carcinogenesis? Skin tumor experiments with MGMT-overexpressing mice.
Topics: Animals; Carcinogenesis; Disease Resistance; DNA Modification Methylases; DNA Repair; DNA Repair Enzymes; Gene Expression; Humans; Methylnitrosourea; Mice; Mice, Transgenic; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins | 2014 |
Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Communication; Cell Differentiation; Cell Transformation, Neoplastic; Cytokines; Dermatitis, Atopic; Disease Models, Animal; Epidermis; Keratinocytes; Membrane Proteins; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; NK Cell Lectin-Like Receptor Subfamily K; Papilloma; Permeability; Plakins; Protein Precursors; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin; Time Factors | 2014 |
Apoptotic effect of pheophorbide a-mediated photodynamic therapy on DMBA/TPA-induced mouse papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogenesis; Caspase 3; Chlorophyll; Female; Immunohistochemistry; In Situ Nick-End Labeling; Mice, Hairless; Papilloma; Photochemotherapy; Photosensitizing Agents; Proliferating Cell Nuclear Antigen; Tetradecanoylphorbol Acetate | 2015 |
Meis1 regulates epidermal stem cells and is required for skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult Stem Cells; Animals; Carcinogens; Carcinoma; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Gene Expression Regulation, Neoplastic; Hair Follicle; Homeodomain Proteins; Keratinocytes; Mice; Mice, Transgenic; Multipotent Stem Cells; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Papilloma; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
In vivo long-term effects of retinoic acid exposure in utero on induced tumours in adult mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Keratoacanthoma; Male; Mice; Papilloma; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate; Treatment Outcome; Tretinoin | 2014 |
Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Proliferation; Cyclooxygenase 2; Eicosanoids; Epidermis; Epithelial Cells; Gene Deletion; Gene Targeting; Hyperplasia; Keratinocytes; Lipid Metabolism; Macrophages; Mice; Myeloid Cells; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
Photodynamic therapy using a novel irradiation source, LED lamp, is similarly effective to photodynamic therapy using diode laser or metal-halide lamp on DMBA- and TPA-induced mouse skin papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminolevulinic Acid; Animals; Female; Lasers, Semiconductor; Mice; Mice, Hairless; Papilloma; Photochemotherapy; Photosensitizing Agents; Porphyrins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
Crosstalk between Desmoglein 2 and Patched 1 accelerates chemical-induced skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma in Situ; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Division; Cocarcinogenesis; Dermis; Desmoglein 2; Epidermis; Gene Knock-In Techniques; Genes, Reporter; Genetic Predisposition to Disease; Genotype; Hair Follicle; Hedgehog Proteins; Hyperplasia; Keratinocytes; Mice; Mice, Transgenic; Papilloma; Patched Receptors; Patched-1 Receptor; Receptors, Cell Surface; Signal Transduction; Skin Neoplasms; Stromal Cells; Tetradecanoylphorbol Acetate; Time Factors | 2015 |
Resistance of R-Ras knockout mice to skin tumour induction.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Proliferation; Dermis; Genetic Association Studies; Genetic Predisposition to Disease; Mice, Inbred C57BL; Mice, Knockout; Papilloma; ras Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2015 |
Notch1 Activation or Loss Promotes HPV-Induced Oral Tumorigenesis.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Carcinoma, Verrucous; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; Disease Progression; DNA Transposable Elements; Female; Humans; Mice; Mice, Transgenic; Mouth Neoplasms; Mutagenesis, Insertional; Neoplasm Invasiveness; Oncogenes; Papilloma; Papillomaviridae; Receptor, Notch1; Skin Neoplasms; Specific Pathogen-Free Organisms; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Virus Infections; Uterine Cervical Neoplasms | 2015 |
Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Cytochrome P-450 CYP2E1; DNA Damage; Hair Follicle; Keratinocytes; Mice; Mice, Knockout; NFATC Transcription Factors; Papilloma; Skin; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate | 2015 |
Dihydro-β-agarofuran sesquiterpenes from celastraceae species as anti-tumour-promoting agents: Structure-activity relationship.
Topics: Animals; Antigens, Viral; Antineoplastic Agents; Celastraceae; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, Inbred ICR; Models, Molecular; Molecular Structure; Papilloma; Sesquiterpenes; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2016 |
Deletion of 14-3-3σ sensitizes mice to DMBA/TPA-induced papillomatosis.
Topics: 14-3-3 Proteins; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Cell Differentiation; Cell Proliferation; Codon, Nonsense; Disease Models, Animal; Down-Regulation; Epidermal Cells; Epidermis; Exons; Female; Gain of Function Mutation; Gene Deletion; Hair Follicle; Heterozygote; Immunohistochemistry; Integrases; Keratinocytes; Male; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2016 |
Lgr4 is crucial for skin carcinogenesis by regulating MEK/ERK and Wnt/β-catenin signaling pathways.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D1; Extracellular Signal-Regulated MAP Kinases; Genetic Predisposition to Disease; Humans; Keratinocytes; MAP Kinase Kinase 1; Mice, Knockout; Neoplasms, Experimental; Papilloma; Phenotype; Receptors, G-Protein-Coupled; RNA Interference; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transfection; Wnt Signaling Pathway | 2016 |
Suppression of skin tumorigenesis in CD109-deficient mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; DNA Damage; Genes, ras; Genetic Predisposition to Disease; Keratinocytes; Mice, Knockout; Mutation; Neoplasm Proteins; NF-E2-Related Factor 2; Papilloma; Phenotype; Phosphorylation; Signal Transduction; Skin Neoplasms; Smad2 Protein; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor beta1 | 2016 |
Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase.
Topics: Animals; Dendritic Cells; Dermatitis, Contact; Disease Progression; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lymph Nodes; Mice; Mice, Inbred C57BL; Models, Animal; Papilloma; Signal Transduction; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2008 |
A novel Src kinase inhibitor reduces tumour formation in a skin carcinogenesis model.
Topics: Adult; Aged; Animals; Anticarcinogenic Agents; Benzodioxoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Humans; Keratinocytes; Keratosis; Male; Mice; Middle Aged; Papilloma; Precancerous Conditions; Quinazolines; Skin Neoplasms; src-Family Kinases; Tetradecanoylphorbol Acetate | 2009 |
Dietary grape seed proanthocyanidins inhibit 12-O-tetradecanoyl phorbol-13-acetate-caused skin tumor promotion in 7,12-dimethylbenz[a]anthracene-initiated mouse skin, which is associated with the inhibition of inflammatory responses.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cyclin D1; Cyclooxygenase 2; Dinoprostone; Female; Grape Seed Extract; Inflammation; Mice; Papilloma; Plant Extracts; Proanthocyanidins; Proliferating Cell Nuclear Antigen; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
IFNgamma promotes papilloma development by up-regulating Th17-associated inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Inflammation; Interferon gamma Receptor; Interferon-gamma; Interleukin-17; Mice; Papilloma; Phosphorylation; Receptors, Interferon; Skin Neoplasms; STAT1 Transcription Factor; Tetradecanoylphorbol Acetate | 2009 |
Activation of P2X(7)-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenosine Triphosphate; Animals; Apoptosis; Blotting, Western; Calcium; Caspase 3; Caspase 9; Caspase Inhibitors; Cells, Cultured; Dose-Response Relationship, Drug; Female; Immunohistochemistry; In Situ Nick-End Labeling; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Papilloma; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; Survival Analysis; Tetradecanoylphorbol Acetate | 2009 |
Selective role for Mek1 but not Mek2 in the induction of epidermal neoplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Genotype; Hyperplasia; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mice, Knockout; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oncogene Protein v-akt; Papilloma; Phosphorylation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Photodynamic therapy using a novel photosensitizer, EC036, is more effective compared with ATX-S10(Na) photodynamic therapy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Female; Lasers, Semiconductor; Mice; Mice, Hairless; Ointments; Papilloma; Photochemotherapy; Photosensitizing Agents; Porphyrins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2009 |
Inhibition of CREB function in mouse epidermis reduces papilloma formation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Carcinogens; Cell Cycle; Cell Proliferation; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Epidermis; Female; Genes, ras; In Situ Nick-End Labeling; Keratinocytes; Male; Mice; Mice, Inbred Strains; Mice, Transgenic; Mutation; Papilloma; Reverse Transcriptase Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Photodynamic therapy with 5-aminolevulinic acid and diamino acid derivatives of protoporphyrin IX reduces papillomas in mice without eliminating transformation into squamous cell carcinoma of the skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminolevulinic Acid; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Kaplan-Meier Estimate; Mice; Mice, Inbred Strains; Papilloma; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Cancer chemopreventive activity of diversin from Ferula diversivittata in vitro and in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Antineoplastic Agents, Phytogenic; Carcinogens; Coumarins; Female; Ferula; Lactones; Mice; Mice, Inbred ICR; Monoterpenes; Papilloma; Phytotherapy; Plant Extracts; Plant Roots; Sesquiterpenes; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2010 |
The prostaglandin receptor EP2 activates multiple signaling pathways and beta-arrestin1 complex formation during mouse skin papilloma development.
Topics: Animals; Arrestins; beta-Arrestins; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Female; Genes, ras; Mice; Mice, Inbred C57BL; Papilloma; Proto-Oncogene Proteins c-akt; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; Skin Neoplasms; src-Family Kinases; Tetradecanoylphorbol Acetate | 2009 |
Cancer chemopreventive activity of oleanane-type triterpenoids from the stem bark of Betula ermanii.
Topics: Animals; Anticarcinogenic Agents; Antigens, Viral; Betula; Carcinogenicity Tests; Female; Mice; Mice, Inbred ICR; Oleanolic Acid; Papilloma; Plant Bark; Plant Stems; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2009 |
The effect of c-myc on stem cell fate influences skin tumor phenotype.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma, Sebaceous; Animals; Carcinogens; Cell Differentiation; Cell Lineage; Crosses, Genetic; Female; Heterozygote; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Mice, Transgenic; Multipotent Stem Cells; Papilloma; Phenotype; Proto-Oncogene Proteins c-myc; Sebaceous Gland Neoplasms; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate; Transgenes | 2010 |
Positron emission tomography imaging of DMBA/TPA mouse skin multi-step tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Progression; Female; Fluorodeoxyglucose F18; Glucose; Mice; Papilloma; Positron-Emission Tomography; Predictive Value of Tests; Radiopharmaceuticals; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tomography, X-Ray Computed | 2010 |
Transforming growth factor beta1 enhances tumor promotion in mouse skin carcinogenesis.
Topics: Animals; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Mice; Mice, Inbred BALB C; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1 | 2010 |
Genetic heterogeneity of inflammatory response and skin tumorigenesis in phenotypically selected mouse lines.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Genetic Drift; Genetic Heterogeneity; Genetic Predisposition to Disease; Genome-Wide Association Study; Inflammation; Mice; Neutrophil Infiltration; Papilloma; Phenotype; Polymorphism, Single Nucleotide; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2010 |
3,3'-diindolylmethane suppresses 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and tumor promotion in mouse skin via the downregulation of inflammatory mediators.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Chemokine CXCL5; Cyclooxygenase 2; Ear; Edema; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation; I-kappa B Kinase; Indoles; Inflammation; Inflammation Mediators; Interleukin-6; Mice; Mice, Inbred ICR; NF-kappa B; Nitric Oxide Synthase Type II; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2010 |
Use of a TGFbeta type I receptor inhibitor in mouse skin carcinogenesis reveals a dual role for TGFbeta signaling in tumor promotion and progression.
Topics: Animals; Benzamides; Dioxoles; Disease Progression; Genes, ras; Mice; Papilloma; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Skin Neoplasms; Smad2 Protein; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1 | 2010 |
Carcinogen-induced squamous papillomas and oncogenic progression in the absence of the SSeCKS/AKAP12 metastasis suppressor correlate with FAK upregulation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; A Kinase Anchor Proteins; Animals; Cell Cycle Proteins; Disease Progression; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2011 |
Decreased incidence of papillomas in mice with impaired EGFR function during multi-stage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Proliferation; ErbB Receptors; Ki-67 Antigen; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Papilloma; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2011 |
Effect of suppressive oligodeoxynucleotides on the development of inflammation-induced papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chemokine CCL2; Chemokine CXCL2; Cyclooxygenase 2; Female; Inflammation; Mice; Oligodeoxyribonucleotides; Ornithine Decarboxylase; Papilloma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
The arcuate nucleus and neuropeptide Y contribute to the antitumorigenic effect of calorie restriction.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Appetite; Arcuate Nucleus of Hypothalamus; Caloric Restriction; Female; Hunger; Male; Mice; Mice, Knockout; Neoplasms, Experimental; Neurons; Neuropeptide Y; Papilloma; RNA, Messenger; Skin Neoplasms; Sodium Glutamate; Tetradecanoylphorbol Acetate | 2011 |
Protective role of cathepsin L in mouse skin carcinogenesis.
Topics: Administration, Topical; Alleles; Animals; Cathepsin L; CD4-Positive T-Lymphocytes; Cell Proliferation; Female; Genotype; Keratinocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Knockout; Papilloma; Polymorphism, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2012 |
Rapamycin and mTORC1 inhibition in the mouse: skin cancer prevention.
Topics: Animals; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Carcinogens; Humans; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Rapamycin is a potent inhibitor of skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Blotting, Western; Carcinogens; Humans; Hyperplasia; Mice; Neoplasm Staging; Papilloma; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; Skin Neoplasms; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2011 |
Increased skin papilloma formation in mice lacking glutathione transferase GSTP.
Topics: Animals; Apoptosis; Cell Proliferation; Glutathione S-Transferase pi; Mice; Oxidative Stress; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Manganese superoxide dismutase is a p53-regulated gene that switches cancers between early and advanced stages.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Disease Progression; Enhancer Elements, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genes, Reporter; Genes, Synthetic; Humans; Mice; Mice, Transgenic; Neoplasm Proteins; Papilloma; Promoter Regions, Genetic; Recombinant Fusion Proteins; Skin Neoplasms; Sp1 Transcription Factor; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Suppressor Protein p53 | 2011 |
Prostaglandin modulation of phorbol ester skin tumor promotion.
Topics: Animals; Arachidonic Acid; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Dinoprost; Dinoprostone; Female; Mice; Mice, Inbred SENCAR; Oxytocics; Papilloma; Prostaglandins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Effects of dose and duration of treatment with the tumor-promoting agent, 12-O-tetradecanoylphorbol-13-acetate on mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Dose-Response Relationship, Drug; Female; Mice; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1980 |
Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) and LMP2A function cooperatively to promote carcinoma development in a mouse carcinogenesis model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Cell Transformation, Viral; Disease Models, Animal; Disease Progression; Gene Expression; Genes, ras; Keratin-14; Mice; Mice, Inbred BALB C; Mice, Transgenic; Mutation; Papilloma; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Viral Matrix Proteins | 2012 |
A keratin 15 containing stem cell population from the hair follicle contributes to squamous papilloma development in the mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Female; Genes, ras; Hair Follicle; Humans; Integrases; Keratin-15; Keratinocytes; Laser Capture Microdissection; Mice; Mice, Transgenic; Mutation; Papilloma; Skin; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate | 2013 |
JWA deficiency suppresses dimethylbenz[a]anthracene-phorbol ester induced skin papillomas via inactivation of MAPK pathway in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Blotting, Western; Carcinogens; Carrier Proteins; Cell Proliferation; Cells, Cultured; DNA Damage; ets-Domain Protein Elk-1; Heat-Shock Proteins; Immunohistochemistry; MAP Kinase Signaling System; Membrane Transport Proteins; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Data; Papilloma; Phosphorylation; Proliferating Cell Nuclear Antigen; Reverse Transcriptase Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2012 |
Photodynamic therapy using a novel photosensitizer, TONS501, is similarly effective to ALA and EC036 photodynamic therapy on DMBA-and TPA-induced mouse skin papilloma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Aminolevulinic Acid; Animals; Disease Models, Animal; Female; Mice; Mice, Hairless; Ointments; Papilloma; Photochemotherapy; Photosensitizing Agents; Porphyrins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Treatment Outcome | 2012 |
Independent genetic control of early and late stages of chemically induced skin tumors in a cross of a Japanese wild-derived inbred mouse strain, MSM/Ms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Crosses, Genetic; Female; Genetic Linkage; Japan; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2012 |
Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Animals, Inbred Strains; Azoxymethane; Cell Transformation, Neoplastic; Chemokines, CXC; Colitis; Colonic Neoplasms; Dermatitis, Contact; Dextran Sulfate; Gene Expression; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Papilloma; Peroxidase; Precancerous Conditions; Receptors, Interleukin-8B; Skin Neoplasms; Statistics, Nonparametric; Tetradecanoylphorbol Acetate; Tumor Burden | 2012 |
The effect of beta-carotene on lung and skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Carotene; Carcinogens; Dose-Response Relationship, Drug; Ferrets; Lung Neoplasms; Mice; Nicotiana; Papilloma; Precancerous Conditions; Skin Neoplasms; Smoke; Tetradecanoylphorbol Acetate | 2002 |
Modulation of epidermal tumor development caused by targeted overexpression of epidermis-type 12S-lipoxygenase.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonate 12-Lipoxygenase; Carcinogens; Down-Regulation; Female; Gene Expression; Isoenzymes; Linoleic Acids; Male; Mice; Mice, Inbred DBA; Mice, Transgenic; Papilloma; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2002 |
Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Carcinogens; Carcinoma, Squamous Cell; Celecoxib; Cocarcinogenesis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Gene Expression; Isoenzymes; Mice; Mice, Transgenic; Papilloma; Phenotype; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Skin; Skin Neoplasms; Sulfonamides; Tetradecanoylphorbol Acetate | 2002 |
Genetic interaction between the unstable v-Ha-RAS transgene (Tg.AC) and the murine Werner syndrome gene: transgene instability and tumorigenesis.
Topics: Animals; Chromosome Mapping; DNA Helicases; Exodeoxyribonucleases; Genes, ras; Genotype; Mice; Mice, Transgenic; Mutation; Papilloma; RecQ Helicases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes; Werner Syndrome; Werner Syndrome Helicase | 2002 |
Progressive iron overload enhances chemically mediated tumor promotion in murine skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Benzoyl Peroxide; Carcinogens; Catalase; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Induction; Enzyme Repression; Glutathione; Iron; Iron Overload; Lipid Peroxidation; Mice; Ornithine Decarboxylase; Oxidative Stress; Papilloma; Reactive Oxygen Species; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2003 |
Survivin expression in mouse skin prevents papilloma regression and promotes chemical-induced tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Female; Immunohistochemistry; Inhibitor of Apoptosis Proteins; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Neoplasm Proteins; Papilloma; Skin; Skin Neoplasms; Survivin; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2003 |
Chemopreventive effects of alpha-santalol on skin tumor development in CD-1 and SENCAR mice.
Topics: Administration, Topical; Animals; Carcinogens; Chemoprevention; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Incidence; Mice; Mice, Inbred SENCAR; Ornithine Decarboxylase; Papilloma; Plant Oils; Sesquiterpenes; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Treatment Outcome; Women's Health | 2003 |
Tumor initiating activity of Helicobacter pylori water extract on mouse skin carcinogenesis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Alleles; Animals; Carcinogens; Cell Fractionation; Cocarcinogenesis; Codon; Deoxyguanosine; Disease Progression; DNA; DNA Adducts; DNA Damage; Female; Genes, ras; Helicobacter pylori; Luminescent Measurements; Mice; Mice, Inbred SENCAR; Oxidative Stress; Papilloma; Peroxidase; Point Mutation; Skin; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate; Water | 2003 |
Expression of enhancing factor/phospholipase A2 in skin results in abnormal epidermis and increased sensitivity to chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abnormalities, Multiple; Animals; Carcinogens; Carcinoma, Squamous Cell; Epidermis; Fibrosarcoma; Genetic Predisposition to Disease; Genotype; Group II Phospholipases A2; Humans; Keratins; Mice; Mice, Transgenic; Neoplasms, Basal Cell; Papilloma; Phenotype; Phospholipases A; Promoter Regions, Genetic; Recombinant Fusion Proteins; Skin; Skin Neoplasms; Tail; Tetradecanoylphorbol Acetate; Transgenes; Vibrissae | 2003 |
Blue light inhibits the growth of skin tumors in the v-Ha-ras transgenic mouse.
Topics: Animals; Epidermis; Female; Genes, ras; Hyperplasia; Keratins; Mice; Mice, Transgenic; Oncogene Protein p21(ras); Papilloma; Phototherapy; Precancerous Conditions; Recombinant Fusion Proteins; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Weight Gain | 2003 |
An anti-tumor necrosis factor-alpha antibody inhibits the development of experimental skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies, Monoclonal; Carcinogens; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Immunity, Innate; Keratinocytes; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Staging; Papilloma; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 2003 |
Cancer preventive potential of trichothecenes from Trichothecium roseum.
Topics: Animals; Anti-Infective Agents; Anticarcinogenic Agents; Antigens, Viral; Carcinogenicity Tests; Cell Survival; Humans; Mice; Mitosporic Fungi; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trichothecenes; Tumor Cells, Cultured | 2003 |
IL-1 alpha, innate immunity, and skin carcinogenesis: the effect of constitutive expression of IL-1 alpha in epidermis on chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA-Binding Proteins; Epidermis; Female; Humans; Immunity, Innate; Interleukin-1; Keratin-14; Keratins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Nuclear Proteins; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2003 |
Evaluation of the Tg.AC assay: specificity testing with three noncarcinogenic pharmaceuticals that induce selected stress gene promoters in vitro and the inhibitory effects of solvent components.
Topics: Acetone; Administration, Topical; Amiloride; Animal Testing Alternatives; Animals; Carcinogenicity Tests; Carcinogens; CCAAT-Enhancer-Binding Proteins; Dimethyl Sulfoxide; Dipyridamole; Dose-Response Relationship, Drug; Drug Antagonism; Drug-Related Side Effects and Adverse Reactions; Female; Male; Mice; Mice, Inbred Strains; Mice, Transgenic; Papilloma; Pharmaceutical Preparations; Predictive Value of Tests; Promoter Regions, Genetic; Pyrimethamine; Skin Neoplasms; Solvents; Tetradecanoylphorbol Acetate; Transcription Factor CHOP; Transcription Factors; Transgenes | 2003 |
c-Jun regulates eyelid closure and skin tumor development through EGFR signaling.
Topics: Animals; Apoptosis; Carcinogens; Cell Division; Epidermal Cells; Epidermal Growth Factor; Epidermis; ErbB Receptors; Eyelids; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Genes, jun; Genetic Predisposition to Disease; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Mice; Mice, Transgenic; Models, Biological; Papilloma; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2003 |
H-ras mutations at codon 61 or 13 in tumors initiated with a NO donor in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinogens; Codon; Female; Genes, ras; Mice; Mutation; Nitric Oxide; Nitro Compounds; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2003 |
The distinct contributions of murine T cell receptor (TCR)gammadelta+ and TCRalphabeta+ T cells to different stages of chemically induced skin cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Models, Animal; Hematopoietic Stem Cells; Liver; Mice; Mice, Knockout; Neoplasm Staging; Papilloma; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Antigen, T-Cell, gamma-delta; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors | 2003 |
Expression of the TGF-beta coreceptor endoglin in epidermal keratinocytes and its dual role in multistage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Carcinoma; Cells, Cultured; Endoglin; Epidermal Cells; Epidermis; Humans; Keratinocytes; Mice; Mice, Mutant Strains; Neoplasms, Experimental; Papilloma; Receptors, Cell Surface; Reference Values; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Vascular Cell Adhesion Molecule-1 | 2003 |
Absence of tumor promoting activity of Euphorbia milii latex on the mouse back skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Euphorbia; Female; Latex; Male; Mice; Mice, Inbred DBA; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2003 |
Free radical generating agents lead to the rapid progression of benign skin tumors to carcinoma in iron-overloaded mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzene Derivatives; Benzoyl Peroxide; Carcinogens; Carcinoma, Squamous Cell; Disease Progression; Female; Free Radicals; Hydrogen Peroxide; Iron; Iron Overload; Iron-Dextran Complex; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Two new anti-tumor promoting serratane-type triterpenoids from the stem bark of Picea jezoensis var. jezoensis.
Topics: Animals; Antigens, Viral; Antineoplastic Agents, Phytogenic; Female; Herpesvirus 4, Human; Inhibitory Concentration 50; Mice; Mice, Inbred ICR; Papilloma; Phytotherapy; Picea; Plant Bark; Plant Extracts; Plant Stems; Skin Neoplasms; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate; Triterpenes | 2003 |
Triterpene acids from the leaves of Perilla frutescens and their anti-inflammatory and antitumor-promoting effects.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Antigens, Viral; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Mice; Mice, Inbred ICR; Otitis; Papilloma; Perilla frutescens; Plant Leaves; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2004 |
Low iron diet retards 12-O-tetradecanoyl phorbol-13-acetate-mediated tumor promotion in murine skin.
Topics: Animals; Benz(a)Anthracenes; Carcinogens; Carcinoma; Catalase; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Iron, Dietary; Mice; Ornithine Decarboxylase; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Only a subset of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin papillomas are promotable by benzoyl peroxide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Carcinogens; Cocarcinogenesis; DNA Primers; Drug Resistance, Neoplasm; Female; Genes, ras; Genetic Predisposition to Disease; Male; Mice; Mutation; Papilloma; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Increased skin carcinogenesis in a keratinocyte directed thioredoxin-1 transgenic mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Humans; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Papilloma; Promoter Regions, Genetic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thioredoxins; Ultraviolet Rays | 2004 |
Anti-tumor-promoting activities of selected pungent phenolic substances present in ginger.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Catechols; Dermatitis; Fatty Alcohols; Female; Guaiacol; HL-60 Cells; Humans; Ketones; Mice; Mice, Inbred ICR; Ornithine Decarboxylase; Papilloma; Plant Extracts; Skin; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zingiber officinale | 1999 |
Mutually exclusive mutations of the Pten and ras pathways in skin tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Progression; Genes, ras; Heterozygote; Homozygote; Loss of Heterozygosity; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Mutation; Papilloma; Protein Tyrosine Phosphatases; PTEN Phosphohydrolase; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins | 2004 |
Antitumor promotional effects of a novel intestinal bacterial metabolite (IH-901) derived from the protopanaxadiol-type ginsenosides in mouse skin.
Topics: Animals; Antineoplastic Agents; Bacteria; Benz(a)Anthracenes; Carcinogens; Cyclooxygenase 2; Dinoprostone; Edema; Extracellular Signal-Regulated MAP Kinases; Female; Ginsenosides; Mice; Mice, Inbred ICR; NF-kappaB-Inducing Kinase; Ornithine Decarboxylase; Papilloma; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sapogenins; Skin; Tetradecanoylphorbol Acetate | 2005 |
An antitumorigenic role for murine 8S-lipoxygenase in skin carcinogenesis.
Topics: Animals; Arachidonate Lipoxygenases; Carcinoma; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Female; Gene Expression; Genes, Tumor Suppressor; Hydroxyeicosatetraenoic Acids; Linoleic Acids, Conjugated; Membrane Proteins; Mice; Mice, Transgenic; Papilloma; Promoter Regions, Genetic; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2005 |
Potential anti-tumor promoting activity of lupane-type triterpenoids from the stem bark of Glochidion zeylanicum and Phyllanthus flexuosus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Antigens, Viral; Antineoplastic Agents, Phytogenic; Female; Herpesvirus 4, Human; Inhibitory Concentration 50; Mice; Mice, Inbred ICR; Papilloma; Phyllanthus; Phytotherapy; Plant Bark; Plant Extracts; Skin Neoplasms; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate; Triterpenes | 2004 |
Raised expression of the antiapoptotic protein ped/pea-15 increases susceptibility to chemically induced skin tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Carcinogens; Caspase 3; Caspases; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; DNA, Antisense; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic; Papilloma; Phosphoproteins; Sarcoma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 2005 |
Mice lacking the p53/p63 target gene Perp are resistant to papilloma development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Adhesion; Cell Differentiation; Cell Growth Processes; Female; Gene Silencing; Genes, p53; Genetic Predisposition to Disease; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Papilloma; Phosphoproteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trans-Activators | 2005 |
Reduced excision repair cross-complementing 1 expression associates with enhanced papilloma formation and fibroblast transformation after genetic disruption of secreted protein acidic and rich in cysteine.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cells, Cultured; DNA Adducts; DNA-Binding Proteins; Embryo, Mammalian; Endonucleases; Female; Fibroblasts; Gene Expression; Genotype; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Osteonectin; Papilloma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Methylation of the O6-methylguanine-DNA methyltransferase promoter suppresses expression in mouse skin tumors and varies with the tumor induction protocol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Diterpenes; DNA Methylation; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Methylnitronitrosoguanidine; Mice; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Papilloma; Promoter Regions, Genetic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cell Line, Tumor; Disease Susceptibility; Down-Regulation; Female; Immunologic Surveillance; Killer Cells, Natural; Ligands; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; NK Cell Lectin-Like Receptor Subfamily K; Papilloma; Receptors, Immunologic; Receptors, Natural Killer Cell; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Burden | 2005 |
Mechanisms of SEPA 0009-induced tumorigenesis in v-rasHa transgenic Tg.AC mice.
Topics: Animals; Carcinogenicity Tests; Carcinogens; Cell Death; Cell Proliferation; Dermatitis, Irritant; Dioxolanes; Dose-Response Relationship, Drug; Epidermis; Female; Gene Expression; Genes, ras; Hyperplasia; Keratin-6; Keratinocytes; Keratins; Mice; Mice, Transgenic; Papilloma; Precancerous Conditions; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Anti-inflammatory and antitumor-promoting effects of the triterpene acids from the leaves of Eriobotrya japonica.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Chromatography, High Pressure Liquid; Eriobotrya; Magnetic Resonance Spectroscopy; Mice; Papilloma; Plant Leaves; Skin Neoplasms; Spectrometry, Mass, Electrospray Ionization; Tetradecanoylphorbol Acetate; Triterpenes | 2005 |
Cancer chemopreventive effect of orally administrated lupane-type triterpenoid on ultraviolet light B induced photocarcinogenesis of hairless mouse.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Carcinogens; Female; Hamamelidaceae; Mice; Mice, Inbred SENCAR; Neoplasms, Radiation-Induced; Papilloma; Seeds; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Triterpenes; Ultraviolet Rays | 2006 |
PTEN loss promotes rasHa-mediated papillomatogenesis via dual up-regulation of AKT activity and cell cycle deregulation but malignant conversion proceeds via PTEN-associated pathways.
Topics: Animals; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Keratin-13; Keratins; MAP Kinase Signaling System; Mice; Mice, Transgenic; Mifepristone; Oncogene Protein v-akt; Papilloma; PTEN Phosphohydrolase; ras Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2006 |
Association of gene expression with sequential proliferation, differentiation and tumor formation in murine skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers; Carcinogens; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Female; Filaggrin Proteins; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Transgenic; Oligonucleotide Array Sequence Analysis; Papilloma; Reverse Transcriptase Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Papilloma development is delayed in osteopontin-null mice: implicating an antiapoptosis role for osteopontin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Growth Processes; Epidermis; Female; Male; Mice; Osteopontin; Papilloma; Sialoglycoproteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Acacetin suppressed LPS-induced up-expression of iNOS and COX-2 in murine macrophages and TPA-induced tumor promotion in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Cell Line; Cocarcinogenesis; Cyclooxygenase 2; Female; Flavones; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred ICR; Nitric Oxide Synthase Type II; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2006 |
Homozygous K5Cre transgenic mice have wavy hair and accelerated malignant progression in a murine model of skin carcinogenesis.
Topics: Alopecia; Animals; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Disease Models, Animal; Disease Progression; DNA Damage; Female; Genes, ras; Genotype; Hair; Hair Follicle; Homozygote; Integrases; Keratin-15; Keratin-5; Keratinocytes; Male; Mammary Glands, Animal; Mice; Mice, Transgenic; Papilloma; Recombination, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Inhibitory effects of asiatic acid on 7,12-dimethylbenz[a]anthracene and 12-O-tetradecanoylphorbol 13-acetate-induced tumor promotion in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Induction; Female; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase Type II; Papilloma; Pentacyclic Triterpenes; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Triterpenes | 2007 |
Pro/antioxidant status and AP-1 transcription factor in murine skin following topical exposure to cumene hydroperoxide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzene Derivatives; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Female; Gene Expression Regulation, Neoplastic; Glutathione; Mice; Mice, Transgenic; Oxidation-Reduction; Oxidative Stress; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2007 |
Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Epidermis; Gene Expression Regulation, Neoplastic; Keratinocytes; Mice; Mice, Transgenic; Nevus, Pigmented; Papilloma; PPAR gamma; Retinoid X Receptor alpha; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Chemopreventive effects of sarcophine-diol on skin tumor development in CD-1 mice.
Topics: 4-Butyrolactone; 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Caspase 3; Caspase 8; Caspase 9; Cell Proliferation; Cyclooxygenase 2; Female; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Haploinsufficiency of the cdc2l gene contributes to skin cancer development in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Codon; Crosses, Genetic; DNA Helicases; Female; Genes, ras; Male; Mice; Mice, Inbred C57BL; Minichromosome Maintenance Complex Component 4; Papilloma; Polymorphism, Restriction Fragment Length; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Expression profile of skin papillomas with high cancer risk displays a unique genetic signature that clusters with squamous cell carcinomas and predicts risk for malignant conversion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Female; Gene Expression Profiling; Immunity, Cellular; Immunophenotyping; Mice; Mice, Inbred SENCAR; Oligonucleotide Array Sequence Analysis; Papilloma; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
New chemically induced skin tumour susceptibility loci identified in a mouse backcross between FVB and dominant resistant PWK.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromosome Mapping; Crosses, Genetic; Drug Resistance; Female; Genes, Dominant; Genetic Linkage; Genetic Predisposition to Disease; Genotype; Male; Mice; Mice, Inbred Strains; Neoplasms, Second Primary; Papilloma; Quantitative Trait Loci; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
The atypical chemokine receptor D6 suppresses the development of chemically induced skin tumors.
Topics: Animals; Chemokine Receptor D6; Disease Susceptibility; Disease-Free Survival; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Keratinocytes; Mice; Mice, Transgenic; Neoplasm Invasiveness; Papilloma; Receptors, CCR10; Receptors, Chemokine; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2007 |
Decreased c-kit function inhibits enhanced skin carcinogenesis in c-Ha-ras protooncogene transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Female; Genes, ras; Humans; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Transgenic; Papilloma; Polymerase Chain Reaction; Promoter Regions, Genetic; Proto-Oncogene Proteins c-kit; Proto-Oncogene Proteins p21(ras); Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2007 |
In vivo long-term effects of retinoic acid exposure in utero on induced hyperplastic epidermal foci in murine skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Carcinogens; Cell Differentiation; Disease Models, Animal; Female; Keratolytic Agents; Mice; Papilloma; Pregnancy; Prenatal Exposure Delayed Effects; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 2007 |
Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Base Sequence; Carcinogens; Carcinoma; Cocarcinogenesis; Female; Genes, ras; Genetic Predisposition to Disease; I-kappa B Kinase; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutation; Neovascularization, Pathologic; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A | 2007 |
Imiquimod treatment of papilloma virus and DMBA /TPA-induced cutaneous skin cancer in Mastomys coucha: an unique animal model system useful for preclinical studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoquinolines; Animals; Antineoplastic Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Imiquimod; Murinae; Papilloma; Papillomavirus Infections; Skin Neoplasms; Tetradecanoylphorbol Acetate; Treatment Outcome | 2007 |
Differential tumor biology effects of double-initiation in a mouse skin chemical carcinogenesis model comparing wild type versus protein kinase Cepsilon overexpression mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinoma, Squamous Cell; Female; Genes, ras; Mice; Mice, Transgenic; Mutation; Papilloma; Protein Kinase C-epsilon; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Hmga1 null mice are less susceptible to chemically induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Genetic Predisposition to Disease; HMGA Proteins; Keratinocytes; Mice; Mice, Knockout; Papilloma; Proto-Oncogene Proteins c-fos; rab GTP-Binding Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Suppressor role of activating transcription factor 2 (ATF2) in skin cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Activating Transcription Factor 2; Animals; Apoptosis; beta Catenin; Carcinogens; Cell Proliferation; Cyclin D1; DNA; Epidermis; Keratinocytes; Mice; Mice, Knockout; Papilloma; Presenilin-1; Proto-Oncogene Proteins c-myb; Receptor, Notch1; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tissue Array Analysis; Tumor Suppressor Proteins | 2008 |
Anti-tumor-Promoting activity of tibolone and its metabolites.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Line, Tumor; Epstein-Barr Virus Nuclear Antigens; Female; Mice; Norpregnenes; Papilloma; Selective Estrogen Receptor Modulators; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Cancer chemopreventive activity of "rosin" constituents of Pinus spez. and their derivatives in two-stage mouse skin carcinogenesis test.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Viral; Carboxylic Acids; Carcinogenicity Tests; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Inbred ICR; Papilloma; Phenanthrenes; Pinus; Resins, Plant; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Effects of oral administration of ciclosporin A on skin carcinogenesis: a study using the two-stage carcinogenesis protocol in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Carcinogens; Cyclosporine; Dose-Response Relationship, Drug; Female; Immunosuppressive Agents; Mice; Mice, Hairless; Neoplasm Staging; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Decreased beta-adrenergic responsiveness in mouse epidermal papillomas during tumor promotion with phorbol myristate acetate.
Topics: Adrenergic beta-Agonists; Animals; Cyclic AMP; Female; Isoproterenol; Mice; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Hairless mouse skin in two-stage chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Drug Resistance; Female; Hyperplasia; Male; Mice; Mice, Hairless; Neoplasm Regression, Spontaneous; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
The study of tumor promotion in a cell culture model for mouse skin--a tissue that exhibits multistage carcinogenesis in vivo.
Topics: Animals; Carcinogens; Cell Differentiation; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Cocarcinogenesis; Enzyme Induction; Epidermis; gamma-Glutamyltransferase; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Effects of 3-isobutyl-1-methylxanthine and cyclic nucleotides on the biochemical processes linked to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 1-Methyl-3-isobutylxanthine; Administration, Topical; Animals; Cocarcinogenesis; Cyclic AMP; Cyclic GMP; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Theophylline | 1981 |
Keratin modifications in epidermis, papillomas, and carcinomas during two-stage carcinogenesis in the SENCAR mouse.
Topics: Animals; Carcinogens; Carcinoma; Female; Keratins; Mice; Mice, Inbred Strains; Molecular Weight; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Simultaneous appearance of keratin modifications and gamma-glutamyltransferase activity as indicators of tumor progression in mouse skin papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acyltransferases; Animals; Carcinoma, Squamous Cell; Female; Histocytochemistry; Keratins; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transglutaminases | 1983 |
Dehydroepiandrosterone (DHEA) and 3 beta-methylandrost-5-en-17-one: inhibitors of 7,12-dimethylbenz[a]anthracene (DMBA)-initiated and 12-O-tetradecanoylphorbol-13-acetate (TPA)-promoted skin papilloma formation in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenes; Animals; Benz(a)Anthracenes; Dehydroepiandrosterone; Drug Administration Schedule; Drug Antagonism; Estradiol; Female; Mice; Papilloma; Phorbols; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate; Uterus | 1984 |
Conversion of herpetic lesions to malignancy by ultraviolet exposure and promoter application.
Topics: Animals; Antibodies, Viral; Carcinoma, Squamous Cell; Herpes Labialis; Lip; Lip Neoplasms; Male; Mice; Neutralization Tests; Papilloma; Simplexvirus; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1981 |
Phorbol myristate acetate uncouples the relationship between beta-adrenergic receptors and adenyl cyclase in mouse epidermis: a phenotypic trait in papillomas.
Topics: Adenylyl Cyclases; Animals; Cocarcinogenesis; Cyclic GMP; Enzyme Activation; Epidermis; Isoproterenol; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Receptors, Adrenergic; Receptors, Adrenergic, beta; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Differential effects of retinoic acid and 7,8-benzoflavone on the induction of mouse skin tumors by the complete carcinogenesis process and by the initiation-promotion regimen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Dose-Response Relationship, Drug; Enzyme Induction; Female; Flavonoids; Injections, Intraperitoneal; Methylcholanthrene; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Relationship of benign papillomas to cancer induction in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Dose-Response Relationship, Drug; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1981 |
Skin painting studies in Syrian hamsters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cricetinae; Dose-Response Relationship, Drug; Female; Male; Melanoma; Mesocricetus; Neoplasms, Experimental; Nicotiana; Papilloma; Plants, Toxic; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Inhibition of 7-bromomethylbenz[a]anthracene-promoted mouse skin tumor formation by retinoic acid and dexamethasone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cocarcinogenesis; Dexamethasone; Drug Interactions; Enzyme Induction; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
Transplacental skin tumor initiation of Ha/ICR mice at different fetal ages.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Fetus; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and ornithine decarboxylase activity by quercetin: possible involvement of lipoxygenase inhibition.
Topics: Animals; DNA; Epidermis; Female; Flavonoids; Lipoxygenase Inhibitors; Mice; Ornithine Decarboxylase Inhibitors; Papilloma; Phorbols; Quercetin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Triethylenemelamine: an initiator of two-stage carcinogenesis in mouse skin which lacks the potential of a complete carcinogen.
Topics: Animals; Carcinogens; Cocarcinogenesis; Female; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Triethylenemelamine | 1983 |
Characteristics of neoplastic progression and tumor behavior in skin carcinogenesis by different methods: an experimental study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Female; Keratoacanthoma; Mice; Neoplasms, Experimental; Papilloma; Precancerous Conditions; Sarcoma, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1980 |
Protection of mice against 7,12-dimethylbenz(a)anthracene-induced skin tumors by immunization with a fluorinated analog of the carcinogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibody Formation; Benz(a)Anthracenes; Cocarcinogenesis; Immunization; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1981 |
Initiation and promotion at different ages and doses in 2200 mice. I. Methods, and the apparent persistence of initiated cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Sensitivity to two-stage carcinogenesis of SENCAR mouse skin grafted to nude mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Skin Transplantation; Species Specificity; Tetradecanoylphorbol Acetate | 1982 |
Mouse skin tumor-initiating activity of 5-, 7-, and 12-methyl- and fluorine-substituted benz[a]anthracenes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogens; Cocarcinogenesis; Female; Hydrocarbons, Fluorinated; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Time Factors | 1982 |
Effect of retinoic acid on the synthesis of glycoproteins of mouse skin tumors during progression from promoted skin through papillomas to carcinomas.
Topics: Animals; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Male; Mice; Molecular Weight; Neoplasm Proteins; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
Tumor promoting activity of 1,8-dihydroxy-3-methyl-9-anthrone (chrysarobin) in female SENCAR mice.
Topics: Animals; Anthracenes; Carcinogens; Female; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Mouse skin application in chemical carcinogenesis.
Topics: Animals; Biological Assay; Carcinogens; Cocarcinogenesis; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Respiratory Tract Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
The tumourigenic and carcinogenic effect of 12-0-tetradecanoylphorbol-13-acetate when applied to the skin of BALB/cA and hairless (hr/hr) mice.
Topics: Amyloidosis; Animals; Female; Kupffer Cells; Male; Mice; Mice, Hairless; Mice, Inbred BALB C; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1983 |
Inhibition of tumor promotion by a biomimetic superoxide dismutase.
Topics: Animals; Antineoplastic Agents; Carcinogens; Female; Mice; Ornithine Decarboxylase; Papilloma; Salicylates; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1983 |
Diazepam inhibition of phorbol ester tumor promotion.
Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Female; Male; Mice; Papilloma; Phorbols; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Comparative tumor-initiating activity of complex mixtures from environmental particulate emissions on SENCAR mouse skin.
Topics: Administration, Topical; Air Pollutants; Animals; Cocarcinogenesis; Female; Fuel Oils; Male; Mice; Mice, Inbred Strains; Papilloma; Petroleum; Probability; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1982 |
Tumor-initiating ability of the twelve monomethylbenz[a]anthracenes.
Topics: Animals; Benz(a)Anthracenes; Carcinogens; Cocarcinogenesis; Dose-Response Relationship, Drug; Female; Mice; Neoplasms, Experimental; Papilloma; Tetradecanoylphorbol Acetate | 1982 |
Must initiators come first? Tumorigenic and carcinogenic effects on skin of 3-methylcholanthrene and TPA in various sequences.
Topics: Animals; Carcinoma; Cell Division; DNA; Drug Synergism; Hyperplasia; Methylcholanthrene; Mice; Mice, Hairless; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Tumour promotion by TCDD in skin of HRS/J hairless mice.
Topics: Animals; Dioxins; Female; Mice; Mice, Hairless; Papilloma; Polychlorinated Dibenzodioxins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Inhibition of mouse skin tumor promotion by several inhibitors of arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Animals; Arachidonic Acids; Biotransformation; Female; Male; Mice; Neoplasms, Experimental; Oxygenases; Papilloma; Phorbols; Phospholipases; Phospholipases A; Phospholipases A2; Prostaglandin Antagonists; Pyrazoles; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Tumorigenic activity of benzo(e)pyrene derivatives on mouse skin and in newborn mice.
Topics: Animals; Animals, Newborn; Benzopyrenes; Biotransformation; Dihydroxydihydrobenzopyrenes; Female; Liver Neoplasms; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Papilloma; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Carcinogenicity of chloroethylene oxide, an ultimate reactive metabolite of vinyl chloride, and bis(chloromethyl)ether after subcutaneous administration and in initiation-promotion experiments in mice.
Topics: Animals; Bis(Chloromethyl) Ether; Ethylene Oxide; Female; Male; Methyl Ethers; Mice; Mutagens; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Soft Tissue Neoplasms; Tetradecanoylphorbol Acetate; Vinyl Chloride | 1980 |
Comparative tumor-initiating activity of methylated benzo(a)pyrene derivatives in mouse skin.
Topics: Animals; Benzopyrenes; Cocarcinogenesis; Female; Methylation; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1980 |
Indomethacin enhancement of TPA tumor promotion in mice.
Topics: Animals; Drug Synergism; Female; Flurbiprofen; Indomethacin; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Paradoxical effect of anthralin on 12-O-tetradecanoylphorbol-13-acetate-induced mouse epidermal ornithine decarboxylase activity, proliferation, and tumor promotion.
Topics: Animals; Anthracenes; Anthralin; Carboxy-Lyases; Cell Division; Enzyme Induction; Epidermal Cells; Epidermis; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1981 |
Inhibitory effect of rikkunshi-to, a traditional Chinese herbal prescription, on tumor promotion in two-stage carcinogenesis in mouse skin.
Topics: Animals; Dermatitis; Drugs, Chinese Herbal; Female; Methanol; Mice; Mice, Inbred ICR; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Water | 1995 |
SENCAR mouse skin tumors produced by promotion alone have A to G mutations in codon 61 of the c-rasHa gene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenine; Animals; Base Sequence; Cocarcinogenesis; Codon; Cytosine; DNA, Neoplasm; Exons; Female; Genes, ras; Mice; Mice, Inbred SENCAR; Mice, Nude; Molecular Sequence Data; Mutation; Nucleic Acid Hybridization; Papilloma; Polymerase Chain Reaction; RNA; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Mouse skin tumor progression results in differential expression of retinoic acid and retinoid X receptors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cell Compartmentation; Epidermis; In Situ Hybridization; Keratins; Mice; Papilloma; Receptors, Retinoic Acid; Retinoid X Receptors; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors | 1995 |
12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mice expressing epidermal-targeted v-fos induces rasHA-activated papillomas and carcinomas without p53 mutation: association of v-fos expression with promotion and tumor autonomy.
Topics: Animals; Base Sequence; Biomarkers; Carcinoma; Cell Differentiation; Cell Transformation, Neoplastic; DNA, Neoplasm; Epidermis; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, p53; Genes, ras; Hyperplasia; Keratins; Keratosis; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Oncogene Proteins v-fos; Papilloma; ras Proteins; RNA, Neoplasm; Tetradecanoylphorbol Acetate | 1995 |
Anti-tumor-promoting activities of euglobals from Eucalyptus plants.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Viral; Burkitt Lymphoma; Cell Cycle; Cocarcinogenesis; Drug Screening Assays, Antitumor; Eucalyptus; Female; Mice; Mice, Inbred ICR; Papilloma; Plant Extracts; Plants, Medicinal; Skin Neoplasms; Structure-Activity Relationship; Terpenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Lack of effect of retinoic acid and fluocinolone acetonide on mirex tumor promotion indicates a novel mirex mechanism.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Base Sequence; Carcinogens; Cell Division; Drug Interactions; Ear, External; Edema; Female; Fluocinolone Acetonide; Genes, ras; Genotype; Mice; Mice, Inbred Strains; Mirex; Molecular Sequence Data; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1995 |
Collagenase expression in transgenic mouse skin causes hyperkeratosis and acanthosis and increases susceptibility to tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acanthosis Nigricans; Animals; Carcinogenicity Tests; Collagenases; Disease Susceptibility; Epidermis; Haptoglobins; Humans; Hyperplasia; Keratosis; Mice; Mice, Transgenic; Papilloma; Promoter Regions, Genetic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Sapintoxin D is a weak tumour promoter in Sencar mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Mice; Mice, Inbred SENCAR; Microscopy, Fluorescence; Papilloma; Phorbol Esters; Random Allocation; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Chemical skin carcinogenesis is prevented in mice by the induced expression of a TGF-beta related transgene.
Topics: Animals; Bone Morphogenetic Proteins; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Division; Epidermis; Methylnitronitrosoguanidine; Mice; Mice, Transgenic; Papilloma; Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1995 |
Genetic alterations cooperate with v-Ha-ras to accelerate multistage carcinogenesis in TG.AC transgenic mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Composition; Base Sequence; Carcinoma, Squamous Cell; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Diglycerides; Female; Fibrosarcoma; Genes, p53; Genes, ras; Mice; Mice, Transgenic; Molecular Sequence Data; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Genetic susceptibility to papilloma progression in SENCAR mice.
Topics: Animals; Female; Hybridization, Genetic; Mice; Mice, Inbred BALB C; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Anti-tumor-promoting action of FK506, a potent immunosuppressive agent.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Dermatitis, Contact; Enzyme Induction; Female; Mice; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Papilloma; Phosphorylation; Skin Neoplasms; Tacrolimus; Tetradecanoylphorbol Acetate | 1993 |
Promotion of skin tumors by 12-O-tetradecanoylphorbol-13-acetate in two generations of descendants of male mice exposed to X-ray irradiation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Female; Fetus; Genes, ras; Male; Mice; Mutation; Neoplasms, Radiation-Induced; Papilloma; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate; Whole-Body Irradiation; X-Rays | 1993 |
Role of ornithine decarboxylase in epidermal tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Line; Cells, Cultured; Fibroblasts; Genetic Vectors; Keratinocytes; Mice; Mice, Inbred BALB C; Ornithine Decarboxylase; Papilloma; Polyamines; Recombinant Proteins; Retroviridae; Skin Neoplasms; Skin Transplantation; Tetradecanoylphorbol Acetate; Transfection | 1995 |
Early overexpression of cyclin D1 protein in mouse skin carcinogenesis.
Topics: Animals; Carcinoma, Squamous Cell; Cyclin D1; Cyclins; Female; Formaldehyde; Gene Expression; Hyperplasia; Immunohistochemistry; Mice; Oncogene Proteins; Papilloma; Paraffin Embedding; Precancerous Conditions; Precipitin Tests; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tissue Fixation | 1995 |
Inhibitors of skin-tumor promotion. XIII. Inhibitory effects of euglobals and their related compounds on Epstein-Barr virus activation and on two-stage carcinogenesis of mouse skin tumors. (2).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Transformed; Female; Herpesvirus 4, Human; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred ICR; Papilloma; Phloroglucinol; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1995 |
Differential expression of prostaglandin H synthase isozymes during multistage carcinogenesis in mouse epidermis.
Topics: Amino Acid Sequence; Animals; Carcinoma; Cell Transformation, Neoplastic; Cocarcinogenesis; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Isoenzymes; Keratinocytes; Mice; Molecular Sequence Data; Papilloma; Prostaglandin-Endoperoxide Synthases; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Tumor-promoting activity of 2,4-dinitrofluorobenzene.
Topics: Animals; Carcinogens; Dermatitis, Contact; Dinitrofluorobenzene; Dose-Response Relationship, Drug; Enzyme Induction; Female; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Hyperplasia; Mice; Mice, Inbred SENCAR; Ornithine Decarboxylase; Papilloma; Protein Kinase C; RNA, Small Nuclear; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Carcinoma formation in NMRI mouse skin painting studies is a process suggesting greater than two stages.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Carcinogenicity Tests; Disease Models, Animal; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Malignant progression of papillomas induced by the initiation--promotion protocol in NMRI mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Disease Models, Animal; Disease Progression; Female; Mice; Mice, Inbred Strains; Models, Statistical; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Effects of methoxychlor on skin tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Models, Animal; Enzyme Induction; Epidermis; Female; Methoxychlor; Mice; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Lack of initiation and promotion potential of deoxynivalenol for skin tumorigenesis in Sencar mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Body Weight; Carcinoma, Squamous Cell; Data Interpretation, Statistical; Female; Hyperplasia; Mice; Organ Size; Papilloma; Random Allocation; Skin; Skin Neoplasms; Spleen; Tetradecanoylphorbol Acetate; Trichothecenes | 1995 |
Focal transgene expression associated with papilloma development in v-Ha-ras-transgenic TG.AC mice.
Topics: Animals; Cell Division; Epidermis; Gene Expression Regulation, Neoplastic; Genes, ras; Hyperplasia; Mice; Mice, Transgenic; Nuclear Proteins; Papilloma; Proliferating Cell Nuclear Antigen; Protein Kinase C; Proto-Oncogene Proteins p21(ras); Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Inhibitory effects of cucurbitane triterpenoids on Epstein-Barr virus activation and two-stage carcinogenesis of skin tumors.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Carbohydrate Sequence; Drug Screening Assays, Antitumor; Female; Herpesvirus 4, Human; Mice; Mice, Inbred ICR; Molecular Sequence Data; Papilloma; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes; Virus Activation | 1994 |
Cancer chemopreventive 3-substituted-4-oxoretinoic acids.
Topics: Alkylation; Animals; Anticarcinogenic Agents; Cricetinae; Drug Stability; Enzyme Induction; Female; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Papilloma; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tretinoin | 1994 |
A course of very small doses of DMBA, each of them allegedly with no promoting potency, acts with clear synergistic effect as a strong promoter of DMBA-initiated mouse skin carcinogenesis. A comparison of the tumorigenic and carcinogenic effects of DMBA (
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Carcinogens; Carcinoma; Drug Synergism; Mice; Mice, Hairless; Papilloma; Skin Neoplasms; Statistics as Topic; Tetradecanoylphorbol Acetate | 1994 |
Consumption of reduced-energy/low-fat diet or constant-energy/high-fat diet during mezerein treatment inhibited mouse skin tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Cocarcinogenesis; Diet, Fat-Restricted; Dietary Carbohydrates; Dietary Fats; Diterpenes; Energy Intake; Female; Mice; Mice, Inbred SENCAR; Papilloma; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1994 |
High dietary retinoic acid prevents malignant conversion of skin papillomas induced by a two-stage carcinogenesis protocol in female SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred SENCAR; Papilloma; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1994 |
Genetics of chemical carcinogenesis--II. Papilloma induction and malignant conversion in susceptible (Car-s) and resistant (Car-R) lines of mice produced by bidirectional selective breeding and in their (Car-S X Car-R) F1 hybrids.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Hybridization, Genetic; Male; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Cytogenetic analysis of malignant skin tumors induced in chemically treated TG-AC transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzene; Carcinoma, Squamous Cell; Female; Gene Expression; Genes, ras; Karyotyping; Male; Mice; Mice, Transgenic; Neoplasm Transplantation; Papilloma; Sarcoma, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
The use of cell proliferation data in modeling of skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cocarcinogenesis; Kinetics; Likelihood Functions; Mice; Models, Biological; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Inhibitory effect of karounidiol on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cocarcinogenesis; Female; Inflammation; Mice; Mice, Inbred ICR; Oleanolic Acid; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 1994 |
Follicular origin of epidermal papillomas in v-Ha-ras transgenic TG.AC mouse skin.
Topics: Animals; Female; Genes, ras; Hair Diseases; In Situ Hybridization; Mice; Mice, Transgenic; Papilloma; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate | 1994 |
Constitutive AP-1 DNA binding and transactivating ability of malignant but not benign mouse epidermal cells.
Topics: Animals; Base Sequence; Carcinoma, Squamous Cell; Chloramphenicol O-Acetyltransferase; DNA; Female; Keratinocytes; Mice; Mice, Nude; Molecular Sequence Data; Neoplasm Transplantation; Papilloma; Proto-Oncogene Proteins c-jun; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transcriptional Activation | 1994 |
2-year carcinogenicity study in the male NMRI mouse with 2-ethylhexyl acrylate by epicutaneous administration.
Topics: Acrylates; Administration, Cutaneous; Air Pollutants, Occupational; Animals; Benzo(a)pyrene; Carcinogenicity Tests; Carcinogens; Carcinoma, Squamous Cell; Male; Mice; Papilloma; Skin Neoplasms; Spectrophotometry, Ultraviolet; Tetradecanoylphorbol Acetate | 1994 |
Effects of krestin (PSK) on tumorigenesis induced by two-stage and complete chemical carcinogenesis.
Topics: Adjuvants, Immunologic; Animals; Antibiotics, Antineoplastic; Benzo(a)pyrene; Carcinoma, Squamous Cell; Female; Macrophages; Mice; Mice, Inbred Strains; Neutrophils; Papilloma; Proteoglycans; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Epidermal expression of transforming growth factor-alpha in transgenic mice: induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression.
Topics: Animals; Base Sequence; DNA Primers; Gene Expression; Genes, ras; Mice; Mice, Transgenic; Molecular Sequence Data; Papilloma; Proto-Oncogene Proteins p21(ras); RNA, Messenger; RNA, Neoplasm; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1994 |
Skin-tumour-promoting activity of processed bidi tobacco in hairless S/RV Cri-ba mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cocarcinogenesis; Female; Mice; Mice, Mutant Strains; Nicotiana; Occupational Exposure; Papilloma; Plant Extracts; Plants, Toxic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Protection against malignant conversion of chemically induced benign skin papillomas to squamous cell carcinomas in SENCAR mice by a polyphenolic fraction isolated from green tea.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Carcinoma, Squamous Cell; Female; Mice; Nitroquinolines; Papilloma; Plant Extracts; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate | 1993 |
Characterization of benzo[a]pyrene-initiated mouse skin papillomas for Ha-ras mutations and protein kinase C levels.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Base Sequence; Benzo(a)pyrene; Codon; DNA, Neoplasm; Epidermis; Female; Genes, ras; Isoenzymes; Mice; Mice, Inbred Strains; Molecular Sequence Data; Oligodeoxyribonucleotides; Papilloma; Point Mutation; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
FVB/N mice: an inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinoma, Squamous Cell; Drug Resistance; Female; Genetic Predisposition to Disease; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1993 |
The reverse experiment in two-stage skin carcinogenesis. It cannot be genuinely performed, but when approximated, it is not innocuous.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Cell Cycle; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Female; Glutathione; Male; Mice; Mice, Hairless; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Anti-tumor promoting activities of natural products. II. Inhibitory effects of digitoxin on two-stage carcinogenesis of mouse skin tumors and mouse pulmonary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Digitoxin; Female; Glycerol; Lung Neoplasms; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Moderate enhancement of the promotion phase of skin tumorigenesis in hairless mice by topical pretreatment with a mitosis-inhibiting epidermal pentapeptide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Amino Acid Sequence; Animals; Carcinogens; Mice; Mice, Hairless; Mitosis; Molecular Sequence Data; Oligopeptides; Papilloma; Pyrrolidonecarboxylic Acid; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Diacylglycerol is an effector of the clonal expansion of cells containing activated Ha-ras genes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenine; Animals; Base Sequence; Clone Cells; Decanoic Acids; Diglycerides; Genes, ras; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Papilloma; Second Messenger Systems; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thymine | 1993 |
Synergistic interaction between the non-phorbol ester-type promoter mirex and 12-O-tetradecanoylphorbol-13-acetate in mouse skin tumor promotion.
Topics: Adenine; Animals; Base Sequence; Carcinogens; Dose-Response Relationship, Drug; Drug Synergism; Female; Genes, ras; Mice; Mice, Inbred Strains; Mirex; Molecular Sequence Data; Mutation; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thymidine | 1994 |
v-jun oncogene suppresses both phorbol ester-induced cell invasion and stromelysin gene expression in a mouse papilloma cell line.
Topics: Animals; Gene Expression Regulation, Neoplastic; Genes, jun; Matrix Metalloproteinase 3; Metalloendopeptidases; Mice; Neoplasm Invasiveness; Papilloma; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1994 |
DNA adducts, cell proliferation and papilloma latency time in mouse skin after repeated dermal application of DMBA and TPA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Cell Division; DNA Damage; Female; Mice; Papilloma; Risk Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Chemically induced skin carcinogenesis in a transgenic mouse line (TG.AC) carrying a v-Ha-ras gene.
Topics: Acetates; Acetic Acid; Animals; Benzoyl Peroxide; Butanols; Carcinogens; Dose-Response Relationship, Drug; Genes, ras; Heterozygote; Homozygote; Mice; Mice, Transgenic; Papilloma; Phenol; Phenols; Promoter Regions, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Lack of initiating capacity of the genotoxic air pollutant 2-nitrofluorene in the mouse skin two-stage carcinogenesis system.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Air Pollutants; Animals; Cocarcinogenesis; Female; Fluorenes; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Transplacental carcinogenicity of cisplatin: initiation of skin tumors and induction of other preneoplastic and neoplastic lesions in SENCAR mice.
Topics: Animals; Cisplatin; Cocarcinogenesis; Female; Kidney Neoplasms; Lung Neoplasms; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Papilloma; Precancerous Conditions; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Southern; Carcinoma; DNA; Genes, p53; Genes, ras; Genotype; Heterozygote; Humans; Male; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Inhibitory effects of 3'-methyl-3-hydroxy-chalcone on proliferation of human malignant tumor cells and on skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Chalcone; Chalcones; Dose-Response Relationship, Drug; HeLa Cells; Humans; Mice; Neoplasm Proteins; Neoplasms; Papilloma; Phosphorylation; Skin Neoplasms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1993 |
The suprabasal expression of alpha 6 beta 4 integrin is associated with a high risk for malignant progression in mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Surface; Biomarkers, Tumor; Diterpenes; Female; Immunohistochemistry; Integrin alpha6beta4; Kinetics; Mice; Mice, Inbred Strains; Papilloma; Risk Factors; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Further studies on the influence of initiation dose on papilloma growth and progression during two-stage carcinogenesis in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Benzoyl Peroxide; Carcinoma, Squamous Cell; Diterpenes; Dose-Response Relationship, Drug; Female; Mice; Papilloma; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Interaction between bovine papillomavirus type 4 and cocarcinogens in the production of malignant tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bovine papillomavirus 1; Bovine papillomavirus 4; Carcinogens; Cattle; Cocarcinogenesis; Female; Mice; Mice, Nude; Papilloma; Tetradecanoylphorbol Acetate | 1993 |
Inhibition of skin tumor promotion by restriction of fat and carbohydrate calories in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinoma; Cocarcinogenesis; Dietary Carbohydrates; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; Energy Intake; Female; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Inhibition of tumor formation from grafted murine papilloma cells by treatment of grafts with staurosporine, an inducer of squamous differentiation.
Topics: Alkaloids; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Differentiation; Disease Models, Animal; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Papilloma; Protein Kinase C; Skin Neoplasms; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1993 |
Vitamin E is a complete tumor promoter in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Carcinogens; Carcinoma; Cocarcinogenesis; Diterpenes; Female; Mice; Papilloma; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Vitamin E | 1993 |
Differential effects of dietary beta-carotene on papilloma and carcinoma formation induced by an initiation-promotion protocol in SENCAR mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Carotene; Carcinoma; Carotenoids; Cocarcinogenesis; Dose-Response Relationship, Drug; Female; Incidence; Male; Mice; Neoplasms, Multiple Primary; Papilloma; Pregnancy; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Overexpression of cyclin D1 in mouse skin carcinogenesis.
Topics: Animals; Base Sequence; Blotting, Northern; Carcinoma, Squamous Cell; Chromosome Mapping; Cyclin D1; Cyclins; Gene Amplification; Gene Expression; Mice; Molecular Sequence Data; Oncogene Proteins; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Nonpromoting 12-deoxyphorbol 13-esters inhibit phorbol 12-myristate 13-acetate induced tumor promotion in CD-1 mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Mice; Papilloma; Phorbol Esters; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Evaluation of chemopreventive effect of dietary selenium-rich egg on mouse skin tumor induced by 2'-(4-nitrophenoxy)oxirane and 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Diet; Eggs; Epoxy Compounds; Glutathione Peroxidase; Male; Mice; Mice, Inbred ICR; Papilloma; Selenium; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Localization and expression of cornifin-alpha/SPRR1 in mouse epidermis, anagen hair follicles, and skin neoplasms.
Topics: Animals; Carcinoma, Squamous Cell; Cornified Envelope Proline-Rich Proteins; Epidermis; Female; Hair Follicle; Immunohistochemistry; Membrane Proteins; Mice; Mirex; Papilloma; Proteins; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
Effect of free fatty acids on two-stage skin carcinogenesis in mice.
Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; Cell Division; Cocarcinogenesis; Croton Oil; Fatty Acids, Nonesterified; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Lipid Peroxidation; Male; Mice; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
Inhibitory effects of caffeic acid phenethyl ester (CAPE) on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in mouse skin and the synthesis of DNA, RNA and protein in HeLa cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Caffeic Acids; Carcinogens; DNA; DNA Damage; Female; HeLa Cells; Humans; Mice; Oxidative Stress; Papilloma; Phenylethyl Alcohol; Protein Biosynthesis; RNA; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
Dose-time response in mouse skin tumor induction by 7, 12-dimethylbenz[a]anthracene and 12-O-tetradecanoyl-phorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Models, Animal; DNA Adducts; Dose-Response Relationship, Drug; Female; Mice; Papilloma; Random Allocation; Skin Neoplasms; Statistics as Topic; Tetradecanoylphorbol Acetate; Time Factors | 1996 |
Carcinogenesis in human skin grafted to SCID mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Carcinogens; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Humans; Keratins; Ki-67 Antigen; Mice; Mice, SCID; Neoplasm Proteins; Nuclear Proteins; Papilloma; Skin Neoplasms; Skin Transplantation; Tetradecanoylphorbol Acetate; Transplantation, Heterologous; Ultraviolet Rays | 1996 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate promoted mouse skin papilloma by digalactosyl diacylglycerols from the fresh water cyanobacterium Phormidium tenue.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anticarcinogenic Agents; Carbohydrate Sequence; Carcinogenicity Tests; Carcinogens; Cyanobacteria; Female; Galactolipids; Glycolipids; Mice; Mice, Inbred ICR; Molecular Sequence Data; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
Regression and progression characteristics of papillomas induced by chrysarobin in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Benzoyl Peroxide; Carcinogens; Carcinoma, Squamous Cell; Female; Free Radicals; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
High-fat diet blocks the inhibition of skin carcinogenesis and reductions in protein kinase C by moderate energy restriction.
Topics: Animals; Body Weight; Carcinogens; Carcinoma; Cocarcinogenesis; Dietary Fats; Energy Intake; Female; Isoenzymes; Mice; Mice, Inbred SENCAR; Papilloma; Protein Kinase C; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
[Skin carcinogenesis induced be neonatal administration of 5-bromo-2'-deoxyuridine and subsequent treatment with 12-O-tetradecanoylphorbol-13-acetate in mice].
Topics: Animals; Bromodeoxyuridine; Carcinogens; Female; Male; Mice; Mice, Hairless; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
[Inhibition of ornithine decarboxylase activity and epidermal papilloma in mice by beta-carotene].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; beta Carotene; Carotenoids; Female; Mice; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Inhibition of pro-inflammatory cytokine gene expression and papilloma growth during murine multistage carcinogenesis by pentoxifylline.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Division; Female; Gene Expression Regulation, Neoplastic; Inflammation Mediators; Interleukin-1; Mice; Papilloma; Pentoxifylline; Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1996 |
Dietary retinoic acid inhibits mouse skin carcinogenesis irrespective of age at initiation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Antineoplastic Agents; Carcinogens; Diet; Diterpenes; Female; Mice; Papilloma; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Tretinoin | 1996 |
Porphyrin-mediated photosensitization has a weak tumor promoting activity in mouse skin: possible role of in situ-generated reactive oxygen species.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Dihematoporphyrin Ether; Drug Synergism; Mice; Papilloma; Photosensitizing Agents; Reactive Oxygen Species; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1996 |
Dietary conjugated linoleic acid modulation of phorbol ester skin tumor promotion.
Topics: Animals; Body Weight; Dietary Fats, Unsaturated; Female; Linoleic Acid; Linoleic Acids; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1996 |
Protection against malignant conversion in SENCAR mouse skin by all trans retinoic acid: inhibition of the ras p21-processing enzyme farnesyltransferase and Ha-ras p21 membrane localization.
Topics: Alkyl and Aryl Transferases; Animals; Carcinoma; Cell Compartmentation; Cell Membrane; Cell Transformation, Neoplastic; Cytosol; Diterpenes; Enzyme Inhibitors; Mice; Papilloma; Proto-Oncogene Proteins p21(ras); Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Transferases; Tretinoin | 1996 |
Up-regulation of vascular endothelial growth factor/vascular permeability factor in mouse skin carcinogenesis correlates with malignant progression state and activated H-ras expression levels.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Transformed; Cell Transformation, Neoplastic; Disease Progression; Endothelial Growth Factors; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, ras; Interleukin 1 Receptor Antagonist Protein; Keratinocytes; Lymphokines; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred SENCAR; Neoplasm Metastasis; Neoplasm Proteins; Neovascularization, Pathologic; Oncogene Protein p21(ras); Papilloma; Precancerous Conditions; Proto-Oncogene Proteins p21(ras); RNA, Messenger; RNA, Neoplasm; Sialoglycoproteins; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1996 |
Anti-tumor promoting effects of naphthoquinone derivatives on short term Epstein-Barr early antigen activation assay and in mouse skin carcinogenesis.
Topics: Animals; Antigens, Viral; Carcinogens; Cells, Cultured; Female; Mice; Mice, Inbred ICR; Naphthoquinones; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Susceptibility of 129/SvEv mice in two-stage carcinogenesis protocols to 12-O-tetradecanoylphorbol-13-acetate promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Biomarkers; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Dermatitis, Contact; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Synergism; Epidermis; Hyperplasia; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Neutrophils; Papilloma; Peroxidase; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1997 |
Effect of spray-dried yogurt and lactic acid bacteria on the initiation and promotion stages of chemically induced skin carcinogenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bifidobacterium; Body Weight; Carcinogens; Carcinoma; Eating; Energy Intake; Female; Lactobacillus acidophilus; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Yogurt | 1997 |
Enhanced skin carcinogenesis in transgenic mice with high expression of glutathione peroxidase or both glutathione peroxidase and superoxide dismutase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Carcinogens; DNA; Female; Glutathione Peroxidase; Humans; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Papilloma; Skin; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 1997 |
Increased expression of G1 cyclins and cyclin-dependent kinases during tumor progression of chemically induced mouse skin neoplasms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Cell Cycle; Cyclin D1; Cyclin D2; Cyclin D3; Cyclin-Dependent Kinases; Cyclins; G1 Phase; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Mice; Oncogene Proteins; Papilloma; S Phase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Altered glucocorticoid receptor expression and function during mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Fluocinolone Acetonide; Hyperplasia; Keratinocytes; Mice; Mice, Inbred Strains; Papilloma; Receptors, Glucocorticoid; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors | 1997 |
Blocking activator protein-1 activity, but not activating retinoic acid response element, is required for the antitumor promotion effect of retinoic acid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Female; Fluocinolone Acetonide; Luciferases; Male; Mice; Mice, Transgenic; Papilloma; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Retinoids; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation; Tretinoin | 1997 |
Chemical carcinogens and antigens contribute to cutaneous tumor promotion by depleting epidermal Langerhans cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens; Carcinogens; Carcinoma, Squamous Cell; Female; Langerhans Cells; Mice; Mice, Inbred BALB C; Papilloma; Picryl Chloride; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Anti-tumor promoting activities of lantadenes on mouse skin tumors and mouse hepatic tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Diethylnitrosamine; Female; Hyperplasia; Liver Neoplasms; Mice; Mice, Inbred ICR; Oleanolic Acid; Papilloma; Phenobarbital; Plants, Medicinal; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
The DNA repair protein O6-methylguanine-DNA methyltransferase protects against skin tumor formation induced by antineoplastic chloroethylnitrosourea.
Topics: Animals; Antineoplastic Agents, Alkylating; DNA Mutational Analysis; Genes, ras; Humans; Methyltransferases; Mice; Mice, Transgenic; Neoplasms, Experimental; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Papilloma; Point Mutation; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Evidence that cutaneous carcinogen-initiated epithelial cells from mice are quiescent rather than actively cycling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antimetabolites, Antineoplastic; Carcinogens; Cell Division; Epidermis; Female; Fluorouracil; Hair Follicle; Mice; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Differential activation of keratinocyte phospholipase A2S by tumor promoters and other irritants.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cytosol; Eicosanoids; Enzyme Activation; Enzyme Inhibitors; Epidermal Cells; Fatty Acids; Isoenzymes; Keratinocytes; Membrane Lipids; Mice; Naphthalenes; Oligonucleotides, Antisense; Papilloma; Phosphatidylcholines; Phospholipases A; Phospholipids; Pyrones; Recombinant Fusion Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1997 |
Transplantation analyses of the immunogenicity of epidermal tumors generated in murine skin two-stage carcinogenesis protocols.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cocarcinogenesis; Female; Graft Rejection; Mice; Mice, Inbred SENCAR; Mice, Nude; Neoplasm Transplantation; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Decreases in phorbol ester-induced papilloma development in v-Ha-ras transgenic TG.AC mice during reduced gene dosage of bcl-2.
Topics: Animals; Carcinogens; Cocarcinogenesis; Female; Gene Expression; Gene Transfer Techniques; Genes, bcl-2; Genes, ras; Genotype; Male; Mice; Mice, Transgenic; Papilloma; Proto-Oncogene Proteins c-bcl-2; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Evidence that mirex promotes a unique population of epidermal cells that cannot be distinguished by their mutant Ha-ras genotype.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cells, Cultured; Cocarcinogenesis; Female; Genes, ras; Genotype; Immunohistochemistry; Keratinocytes; Mice; Mice, Inbred BALB C; Mirex; Mutation; Nitrosourea Compounds; Papilloma; S Phase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Evidence that initiated keratinocytes clonally expand into multiple existing hair follicles during papilloma histogenesis in SENCAR mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Clone Cells; Female; Hair Diseases; Hair Follicle; Keratinocytes; Mice; Mice, Inbred SENCAR; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Telomerase and cell proliferation in mouse skin papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Mice; Mice, Inbred Strains; Mitotic Index; Papilloma; Polymerase Chain Reaction; Skin Neoplasms; Telomerase; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
Mathematical modeling of skin papilloma data in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Cycle; Mice; Mice, Inbred SENCAR; Models, Biological; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Analysis of two inbred strains of mice derived from the SENCAR stock with different susceptibility to skin tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Surface; Biomarkers, Tumor; Carcinogens; Cyclin D1; Disease Susceptibility; Female; Immunohistochemistry; Integrin alpha6beta4; Integrins; Mice; Mice, Inbred Strains; Papilloma; Proliferating Cell Nuclear Antigen; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor beta | 1998 |
Topical retinoic acid reduces skin papilloma formation but resistant papillomas are at high risk for malignant conversion.
Topics: Administration, Topical; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Biomarkers, Tumor; Carcinogens; Carcinoma, Basal Cell; Cell Transformation, Neoplastic; Disease Progression; Diterpenes; Female; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Inbred SENCAR; Papilloma; Phenotype; Precancerous Conditions; Receptors, Retinoic Acid; Retinoid X Receptors; Risk Factors; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Transcription Factors; Transforming Growth Factor beta; Tretinoin | 1998 |
Different expression of prostaglandin-H synthase isozymes and lipoxygenases during multistage carcinogenesis in mouse skin.
Topics: Animals; Arachidonate Lipoxygenases; Carcinoma; Cyclooxygenase 1; Cyclooxygenase 2; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Hydroxyeicosatetraenoic Acids; Isoenzymes; Linoleic Acids; Linoleic Acids, Conjugated; Membrane Proteins; Mice; Papilloma; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1997 |
Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Carcinogens; Centrosome; Disease Susceptibility; Epidermis; Female; Gene Amplification; Humans; Keratins; Male; Mice; Mice, Transgenic; Mutagenesis, Site-Directed; Papilloma; Promoter Regions, Genetic; Proto-Oncogene Proteins p21(ras); ras Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes; Tumor Suppressor Protein p53 | 1998 |
VEGF/VPF overexpression in skin of transgenic mice induces angiogenesis, vascular hyperpermeability and accelerated tumor development.
Topics: Animals; Capillary Permeability; Endothelial Growth Factors; Genes, ras; Hyperplasia; Keratins; Lymphokines; Mice; Mice, Transgenic; Neovascularization, Pathologic; Neovascularization, Physiologic; Papilloma; Precancerous Conditions; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Regulatory Sequences, Nucleic Acid; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Anti-tumor-promoting activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. (I).
Topics: Animals; Anticarcinogenic Agents; Antigens, Viral; Carboxylic Acids; Fumonisins; Ginsenosides; Male; Mice; Mice, Inbred ICR; Papilloma; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Eflornithine; Genes, ras; Keratoacanthoma; Mice; Mice, Transgenic; Ornithine Decarboxylase; Papilloma; Proliferating Cell Nuclear Antigen; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Squamous cell hyperplastic foci: precursors of cutaneous papillomas induced in SENCAR mice by a two-stage carcinogenesis regimen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Epidermis; Female; Hyperplasia; Mice; Mice, Inbred SENCAR; Neoplasm Regression, Spontaneous; Neoplasm Staging; Papilloma; Precancerous Conditions; Sebaceous Glands; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Influence of diet restriction and tumor promoter dose on cell proliferation, oxidative DNA damage and rate of papilloma appearance in the mouse skin after initiation with DMBA and promotion with TPA.
Topics: 8-Hydroxy-2'-Deoxyguanosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Cell Division; Deoxyguanosine; Diet; DNA; DNA Damage; Immunohistochemistry; Male; Mice; Oxidative Stress; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Anti-tumor-promoting activity of diterpenes from Excoecaria agallocha.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Viral; Carcinogens; Diterpenes; Euphorbiaceae; Female; Humans; Mice; Mice, Inbred ICR; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Virus Activation | 1998 |
Effect of the viable-yellow (A(vy)) agouti allele on skin tumorigenesis and humoral hypercalcemia in v-Ha-ras transgenic TGxAC mice.
Topics: Agouti Signaling Protein; Alleles; Animals; Base Sequence; Body Weight; DNA Primers; Genes, ras; Hypercalcemia; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Papilloma; Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Analysis of centrosome abnormalities and angiogenesis in epidermal-targeted p53172H mutant and p53-knockout mice after chemical carcinogenesis: evidence for a gain of function.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Centrosome; Disease Progression; Endothelial Growth Factors; Genes, p53; Humans; Lymphokines; Mice; Mice, Knockout; Neovascularization, Pathologic; Papilloma; Phenotype; Point Mutation; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thrombospondin 1; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Arsenic enhancement of skin neoplasia by chronic stimulation of growth factors.
Topics: Animals; Antibodies; Arsenic; Cell Division; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Immunohistochemistry; Mice; Mice, Transgenic; Papilloma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tissue Distribution; Transforming Growth Factor alpha | 1998 |
Augmentation of 12-O-tetradecanoyl 13-phorbol acetate-mediated tumor promoting response by the porphyrin photosensitization of 7,12-dimethyl benz[a]anthracene-initiated murine skin: role of in situ generated reactive oxygen species.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Mice; Papilloma; Photosensitivity Disorders; Photosensitizing Agents; Porphyrins; Reactive Oxygen Species; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Genetic deletion of p21WAF1 enhances papilloma formation but not malignant conversion in experimental mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Differentiation; Biomarkers; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cocarcinogenesis; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Disease Progression; Epidermis; Gene Deletion; Genes, p53; Genotype; Hyperplasia; Mice; Mice, Knockout; Mitotic Index; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 1999 |
Altered expression of interleukin-1 receptor antagonist in different stages of mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthralin; Blotting, Northern; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Cell Polarity; Cytoplasm; Disease Progression; Epidermis; Gene Expression Regulation, Neoplastic; Hyperplasia; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Keratinocytes; Mice; Mice, Inbred SENCAR; Neoplasm Proteins; Papilloma; Precancerous Conditions; RNA, Messenger; RNA, Neoplasm; Sialoglycoproteins; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1999 |
Anti-carcinogenic activity of Taraxacum plant. I.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Carboxylic Acids; Female; Fumonisins; Humans; Mice; Mice, Inbred ICR; Papilloma; Plant Extracts; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Cancer chemopreventive agents (antitumor-promoters) from Ajuga decumbens.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antineoplastic Agents, Phytogenic; Antiviral Agents; Carcinogens; Female; Glycerol; Herpesvirus 4, Human; Lung Neoplasms; Mice; Mice, Inbred ICR; Papilloma; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Anti-tumor promoting activity of polyphenols from Cowania mexicana and Coleogyne ramosissima.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Antineoplastic Agents; Drug Screening Assays, Antitumor; Flavonoids; Herpesvirus 4, Human; Humans; Mice; Mice, Inbred ICR; Papilloma; Phenols; Plant Extracts; Plants, Medicinal; Polymers; Polyphenols; Rosales; Skin Neoplasms; Specific Pathogen-Free Organisms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virus Activation | 1999 |
Tumor suppression by p27Kip1 and p21Cip1 during chemically induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Carcinogens; Carcinoma; Cell Cycle Proteins; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Genes, ras; Genes, Tumor Suppressor; Intestinal Neoplasms; Keratinocytes; Mice; Mice, Knockout; Microtubule-Associated Proteins; Mutation; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins | 1999 |
Dose-dependent mutation profile in the c-Ha-ras proto-oncogene of skin tumors in mice initiated with benzo[a]pyrene.
Topics: Administration, Cutaneous; Amino Acid Substitution; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma in Situ; Cocarcinogenesis; Codon; DNA; DNA Mutational Analysis; DNA, Neoplasm; Dose-Response Relationship, Drug; Epidermis; Exons; Female; Genes, ras; Hyperplasia; Keratoacanthoma; Mice; Papilloma; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Proteins p21(ras); Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Induction of melanoma in TPras transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Albinism; Animals; Carcinoma; Gene Expression Regulation; Genes, ras; Genetic Predisposition to Disease; Hair Color; Hyperplasia; Melanocytes; Melanoma; Mice; Mice, SCID; Mice, Transgenic; Monophenol Monooxygenase; Neoplasm Metastasis; Neoplasms, Radiation-Induced; Papilloma; Promoter Regions, Genetic; Skin Neoplasms; Skin Pigmentation; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1999 |
A multihit, multistage model of chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA Mutational Analysis; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Keratinocytes; Keratins; Mice; Models, Biological; Neoplasm Proteins; Papilloma; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; S Phase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Skin tumorigenesis by initiators and promoters of different chemical structures in lines of mice selectively bred for resistance (Car-r) or susceptibility (Car-s) to two-stage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Benzoyl Peroxide; Carcinoma; Methylnitrosourea; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mouse epidermis coexpressing transforming growth factor-alpha and v-fos: acceleration of autonomous papilloma formation and malignant conversion via c-Ha-ras activation.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, ras; Humans; Mice; Mice, Transgenic; Oncogene Proteins v-fos; Papilloma; Proto-Oncogene Proteins p21(ras); Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1999 |
Transgenic mice overexpressing protein kinase Cdelta in the epidermis are resistant to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Humans; Isoenzymes; Keratin-14; Keratins; Keratosis; Male; Mice; Mice, Transgenic; Neoplasm Proteins; Papilloma; Protein Kinase C; Protein Kinase C-delta; Sex Factors; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
A farnesyl transferase inhibitor suppresses TPA-mediated skin tumor development without altering hyperplasia in the ras transgenic Tg.AC mouse.
Topics: Alkyl and Aryl Transferases; Animals; Benzazepines; Crosses, Genetic; Enzyme Inhibitors; Farnesyltranstransferase; Female; Genes, ras; Globins; Homozygote; Hyperplasia; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Transgenic; Papilloma; Promoter Regions, Genetic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2000 |
Induction of skin papillomas, carcinomas, and sarcomas in mice in which the connexin 43 gene is heterologously deleted.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Connexin 43; Fibrosarcoma; Gene Deletion; Genes, ras; Mice; Mice, Inbred C57BL; Papilloma; Point Mutation; Sarcoma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Cancer chemopreventive activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis.
Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Female; Focal Nodular Hyperplasia; Ginsenosides; Liver Neoplasms, Experimental; Mice; Mice, Inbred ICR; Mice, Inbred SENCAR; Nitrates; Nitro Compounds; Panax; Papilloma; Phenobarbital; Plants, Medicinal; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vietnam | 1999 |
Human papillomavirus types 16 E6 and E7 contribute differently to carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Transgenic; Mutation; Oncogene Proteins, Viral; Papilloma; Papillomavirus E7 Proteins; Repressor Proteins; Severity of Illness Index; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Evidence that the epidermal targets of carcinogen action are found in the interfollicular epidermis of infundibulum as well as in the hair follicles.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Epidermis; Female; Hair Follicle; Mice; Mice, Inbred SENCAR; Papilloma; Regeneration; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2000 |
Transgenic mice overexpressing protein kinase C epsilon in their epidermis exhibit reduced papilloma burden but enhanced carcinoma formation after tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Epidermis; Female; Humans; Isoenzymes; Male; Mice; Mice, Transgenic; Papilloma; Phenotype; Protein Kinase C; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Development and initial characterization of several new inbred strains of SENCAR mice for studies of multistage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Mice; Mice, Inbred SENCAR; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Antioxidant and anti-tumor promoting activities of the methanol extract of heat-processed ginseng.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Bacteriophage phi X 174; Brain; Carcinogens; DNA, Viral; Enzyme Activation; Female; Gene Expression Regulation, Enzymologic; HL-60 Cells; Hot Temperature; Humans; Hydrogen Peroxide; Lipid Peroxidation; Male; Methanol; Mice; Mice, Inbred ICR; Ornithine Decarboxylase; Panax; Papilloma; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; RNA, Messenger; Skin; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 2000 |
Anti-tumor-promoting effects of isoflavonoids on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis.
Topics: Animals; Body Weight; Carcinogens; Female; Herpesvirus 4, Human; Isoflavones; Mice; Mice, Inbred ICR; Papilloma; Plant Extracts; Rosales; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Virus Activation | 2000 |
Inhibitory effect of flavonoids from citrus plants on Epstein-Barr virus activation and two-stage carcinogenesis of skin tumors.
Topics: Animals; Antigens, Viral; Female; Flavonoids; Mice; Mice, Inbred ICR; Papilloma; Plant Extracts; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Virus Activation | 2000 |
Chemopreventive effects of sage oil on skin papillomas in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, Topical; Animals; Anticarcinogenic Agents; Cell Division; Cell Survival; Injections, Intraperitoneal; Lamiaceae; Lethal Dose 50; Mice; Papilloma; Plant Oils; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
The neurofibromatosis type 1 (Nf1) tumor suppressor is a modifier of carcinogen-induced pigmentation and papilloma formation in C57BL/6 mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; DNA Mutational Analysis; Female; Genes, Neurofibromatosis 1; Genes, ras; Humans; Mice; Mice, Inbred C57BL; Papilloma; Skin; Skin Neoplasms; Skin Pigmentation; Tetradecanoylphorbol Acetate | 2000 |
Aberrant cell cycle progression contributes to the early-stage accelerated carcinogenesis in transgenic epidermis expressing the dominant negative TGFbetaRII.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Carcinogens; Carcinoma, Squamous Cell; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cell Transformation, Neoplastic; Centrosome; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p27; Epidermal Cells; Gene Expression; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Mitosis; Papilloma; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Tetradecanoylphorbol Acetate; Time Factors; Tumor Suppressor Proteins | 2000 |
Targeted disruption of the epidermal growth factor receptor inhibits development of papillomas and carcinomas from human papillomavirus-immortalized keratinocytes.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Line, Transformed; Cell Transformation, Viral; Cocarcinogenesis; Disease Progression; ErbB Receptors; Gene Expression; Genes, ras; Genotype; Humans; Keratinocytes; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Oncogene Proteins, Viral; Papilloma; Papillomaviridae; Papillomavirus E7 Proteins; Repressor Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Flow Cytometry; Immunity, Innate; Immunohistochemistry; In Situ Hybridization, Fluorescence; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Papilloma; Proto-Oncogene Proteins p21(ras); Skin; Skin Neoplasms; Telomerase; Telomere; Tetradecanoylphorbol Acetate; Time Factors; Tumor Suppressor Protein p53 | 2000 |
Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cattle; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Dimerization; Disease Progression; Epidermis; ErbB Receptors; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Genes, ras; Genes, Synthetic; Hyperplasia; Keratins; Male; Mice; Mice, Inbred ICR; Mice, Transgenic; Neoplasm Proteins; Papilloma; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Rats; Receptor, ErbB-2; Receptor, ErbB-3; Recombinant Fusion Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2000 |
Antitumor-promoting effects of cyclic diarylheptanoids on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Diarylheptanoids; Dose-Response Relationship, Drug; Female; Herpesvirus 4, Human; Humans; Hydrocarbons, Cyclic; Mice; Mice, Inbred ICR; Papilloma; Skin Neoplasms; Specific Pathogen-Free Organisms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Virus Activation | 2000 |
A simple phenolic antioxidant protocatechuic acid enhances tumor promotion and oxidative stress in female ICR mouse skin: dose-and timing-dependent enhancement and involvement of bioactivation by tyrosinase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Biotransformation; Carcinogens; Dermatitis, Contact; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Female; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Hydrogen Peroxide; Hydroxybenzoates; Mice; Mice, Inbred ICR; Monophenol Monooxygenase; Oxidative Stress; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Development of spontaneous hyperplastic skin lesions and chemically induced skin papillomas in transgenic mice expressing human papillomavirus type 16 E6/E7 genes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Female; Gene Expression; Humans; Hyperplasia; Mice; Mice, Inbred ICR; Mice, Transgenic; Monophenol Monooxygenase; Oncogene Proteins, Viral; Papilloma; Papillomaviridae; Papillomavirus E7 Proteins; Pregnancy; Repressor Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Cooperation between Ha-ras and fos or transforming growth factor alpha overcomes a paradoxic tumor-inhibitory effect of p53 loss in transgenic mouse epidermis.
Topics: Animals; Carcinogens; Epidermis; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, p53; Genes, ras; Keratins; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Transgenic; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 2000 |
Cancer chemopreventive agents, labdane diterpenoids from the stem bark of Thuja standishii (Gord.) Carr.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; beta Carotene; Carboxylic Acids; Carcinogens; Diterpenes; Female; Humans; Mice; Mice, Inbred ICR; Naphthalenes; Nasopharyngeal Neoplasms; Neoplasms; Papilloma; Plant Extracts; Plant Stems; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trees | 2000 |
Anti-tumor-promoting effects of glycoglycerolipid analogues on two-stage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Antineoplastic Agents; Biological Assay; Carcinogens; Female; Glycolipids; Lipids; Mice; Mice, Inbred ICR; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2000 |
Retinoic acid (RA) receptor transcriptional activation correlates with inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase (ODC) activity by retinoids: a potential role for trans-RA-induced ZBP-89 in ODC inhibition.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Blotting, Northern; Blotting, Western; Carcinogens; Cell Survival; Collagenases; DNA-Binding Proteins; Dose-Response Relationship, Drug; Epidermis; Epithelial Cells; Female; HeLa Cells; Humans; Mice; Mice, Hairless; Neoplasms, Experimental; Ornithine Decarboxylase Inhibitors; Papilloma; Promoter Regions, Genetic; Protein Binding; Protein Kinases; Rats; Receptors, Retinoic Acid; Response Elements; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinoids; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Trachea; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Ultraviolet Rays | 2001 |
Cancer chemopreventive activity of 3,5,6,7,8,3',4'-heptamethoxyflavone from the peel of citrus plants.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Citrus; Female; Flavones; Flavonoids; Mice; Nitro Compounds; Papilloma; Plant Extracts; Skin Neoplasms; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Analysis of c-Ha-ras gene mutations in skin tumors induced in carcinogenesis-susceptible and carcinogenesis-resistant mice by different two-stage protocols or tumor promoter alone.
Topics: Animals; Benz(a)Anthracenes; Benzoyl Peroxide; Carcinogens; Carcinoma, Squamous Cell; DNA Primers; Drug Resistance, Neoplasm; Genes, ras; Genetic Predisposition to Disease; Mice; Mice, Inbred Strains; Mutation; Papilloma; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
[p53 gene mutations in mouse skin tumors induced by DMBA-TPA-MNNG].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Exons; Genes, p53; Methylnitronitrosoguanidine; Mice; Mice, Inbred SENCAR; Papilloma; Point Mutation; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Two-stage carcinogenesis in NMRI mice: intravaginal application of 7,12-dimethylbenz[a]anthracene as initiator followed by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate as promoter.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Administration, Intravaginal; Animals; Carcinogens; Carcinoma; Cocarcinogenesis; Drug Synergism; Female; Hyperplasia; Leukemia, Experimental; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Models, Animal; Neoplasms, Experimental; Organ Specificity; Ovarian Neoplasms; Papilloma; Precancerous Conditions; Sarcoma, Experimental; Specific Pathogen-Free Organisms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Vagina; Vaginal Neoplasms | 1980 |
Age-dependent skin tumorigenesis and transgene expression in the Tg.AC (v-Ha-ras) transgenic mouse.
Topics: Age Factors; Aging; Animals; Carcinogens; Centrifugation, Density Gradient; Female; Flow Cytometry; Genes, ras; Globins; Integrin beta1; Keratinocytes; Mice; Mice, Transgenic; Neoplasms, Radiation-Induced; Papilloma; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transgenes; Ultraviolet Rays | 2001 |
Targeted expression of bcl-2 to murine basal epidermal keratinocytes results in paradoxical retardation of ultraviolet- and chemical-induced tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Female; Genes, ras; Humans; Keratinocytes; Mice; Mice, Transgenic; Mutagenesis; Papilloma; Proto-Oncogene Proteins c-bcl-2; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2001 |
Relation of skin polyamines to the hairless phenotype in transgenic mice overexpressing spermidine/spermine N-acetyltransferase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetyltransferases; Aging; Alopecia; Animals; Animals, Newborn; Carcinogens; Mice; Mice, Transgenic; Neoplasm Staging; Ornithine Decarboxylase; Papilloma; Phenotype; Polyamines; Putrescine; Reference Values; Skin; Skin Neoplasms; Spermidine; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Suppression of skin tumorigenesis in c-Jun NH(2)-terminal kinase-2-deficient mice.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; Papilloma; Phosphorylation; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2001 |
Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Catalytic Domain; Cattle; DNA-Binding Proteins; Female; Gastric Mucosa; Genes, p53; Genetic Therapy; Hyperplasia; Keratinocytes; Keratins; Mice; Mice, Knockout; Mice, Transgenic; Mouth Mucosa; Neoplasms, Experimental; Papilloma; Protein Subunits; RNA; Skin; Skin Neoplasms; Stomach; Telomerase; Telomere; Tetradecanoylphorbol Acetate; Vagina; Wound Healing | 2001 |
Topical and oral administration of the natural water-soluble antioxidant from spinach reduces the multiplicity of papillomas in the Tg.AC mouse model.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Antioxidants; Body Weight; Carcinogens; Disease Models, Animal; Female; Genes, ras; Genotype; Mice; Mice, Transgenic; Papilloma; Plant Extracts; Skin Neoplasms; Spinacia oleracea; Survival Analysis; Tetradecanoylphorbol Acetate | 2001 |
Cancer chemopreventive agents, 4-phenylcoumarins from Calophyllum inophyllum.
Topics: Animals; Anticarcinogenic Agents; Antigens, Viral; Carcinogens; Coumarins; Female; Herpesvirus 4, Human; Humans; Mice; Mice, Inbred ICR; Papilloma; Plant Extracts; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trees; Virus Activation | 2001 |
Influence of beta1 integrins on epidermal squamous cell carcinoma formation in a transgenic mouse model: alpha3beta1, but not alpha2beta1, suppresses malignant conversion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Antigens, Neoplasm; Basigin; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cell Transformation, Neoplastic; Female; Integrin alpha3beta1; Integrins; Keratinocytes; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Papilloma; Receptors, Collagen; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tetraspanin 28 | 2001 |
Nitroglycerin: a NO donor inhibits TPA-mediated tumor promotion in murine skin.
Topics: Animals; Carcinogens; Mice; Nitric Oxide Donors; Nitroglycerin; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Cancer chemopreventive agents, serratane-type triterpenoids from Picea jezoensis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Viral; Female; Humans; Mice; Mice, Inbred ICR; Papilloma; Plants; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2001 |
Avicins, a family of triterpenoid saponins from Acacia victoriae (Bentham), suppress H-ras mutations and aneuploidy in a murine skin carcinogenesis model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acacia; Aneuploidy; Animals; Dioxoles; Disease Models, Animal; Female; Genes, ras; Humans; Jurkat Cells; Mice; Mice, Inbred SENCAR; Papilloma; Phenanthridines; Phytotherapy; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2001 |
Lack of effect of 94 GHz radio frequency radiation exposure in an animal model of skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Carcinogens; Cocarcinogenesis; Dose-Response Relationship, Drug; Drug Administration Schedule; Electromagnetic Fields; Female; Incidence; Mice; Mice, Inbred SENCAR; Neoplasms, Radiation-Induced; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Inhibitory effect of flavonoid derivatives on Epstein-Barr virus activation and two-stage carcinogenesis of skin tumors.
Topics: Animals; Carcinogens; Dose-Response Relationship, Drug; Female; Flavonoids; Herpesvirus 4, Human; Lymphocytes; Mice; Mice, Inbred ICR; Models, Chemical; Papilloma; Quercetin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Cancer chemopreventive activity of naphthoquinones and their analogs from Avicennia plants.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Viral; Carcinogens; Female; Humans; In Vitro Techniques; Mice; Mice, Inbred ICR; Naphthoquinones; Papilloma; Plant Extracts; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virus Activation | 2001 |
Lack of promotion of 7,12-dimethylbenz[a]anthracene-initiated mouse skin carcinogenesis by 1.5 GHz electromagnetic near fields.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenocorticotropic Hormone; Animals; Carcinogens; Carcinoma, Squamous Cell; Corticosterone; Electromagnetic Fields; Epidermis; Female; Incidence; Melatonin; Mice; Mice, Inbred ICR; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Regulation of the differentiation-related gene Drg-1 during mouse skin carcinogenesis.
Topics: Animals; Carcinogens; Cell Cycle Proteins; Cell Differentiation; Cell Transformation, Neoplastic; Genes, ras; Intracellular Signaling Peptides and Proteins; Keratinocytes; Mice; Mice, Inbred C57BL; Papilloma; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Confirmation of the mapping of a 12-O-tetradecanoylphorbol-13-acetate promotion susceptibility locus, Psl1, to distal mouse chromosome 9.
Topics: Animals; Carcinogens; Chromosome Mapping; Genetic Predisposition to Disease; Mice; Neoplasm Proteins; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Loss of critical palindromic transgene promoter sequence in chemically induced Tg.AC mouse skin papillomas expressing transgene-derived mRNA.
Topics: Animals; Carcinogens; Gene Expression Regulation, Neoplastic; Genes, ras; Genetic Predisposition to Disease; Mice; Mice, Transgenic; Papilloma; Promoter Regions, Genetic; RNA, Messenger; Sequence Deletion; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Inhibition of both skin and lung tumorigenesis by Car-R mouse-derived cancer modifier loci.
Topics: Alleles; Animals; Animals, Outbred Strains; Carcinogenicity Tests; Carcinogens; Female; Genetic Predisposition to Disease; Inbreeding; Incidence; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Phenotype; Polymerase Chain Reaction; Polymorphism, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urethane | 2002 |
Cancer chemopreventive activity of Achyranthes aspera leaves on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis.
Topics: Achyranthes; Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Herpesvirus 4, Human; Mice; Mice, Inbred ICR; Papilloma; Plant Extracts; Plant Leaves; Plant Preparations; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virus Activation | 2002 |
Deficiency of c-Jun-NH(2)-terminal kinase-1 in mice enhances skin tumor development by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; DNA; Mice; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; Papilloma; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2002 |
Overexpression of a dominant-negative ornithine decarboxylase in mouse skin: effect on enzyme activity and papilloma formation.
Topics: Animals; Anthracenes; Blotting, Western; Carcinogens; Genes, Dominant; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Mutation; Neoplasm Transplantation; Ornithine Decarboxylase; Papilloma; Protein Binding; Skin; Tetradecanoylphorbol Acetate; Time Factors | 2002 |
Cancer chemopreventive effects of a Brazilian folk medicine, Juca, on in vivo two-stage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Brazil; Caesalpinia; Female; Fruit; Gallic Acid; Medicine, Traditional; Mice; Mice, Inbred ICR; Papilloma; Phytotherapy; Plant Extracts; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2002 |
Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Death; Cell Differentiation; Cell Division; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; DNA Adducts; Female; Immunohistochemistry; Isoenzymes; Keratinocytes; Membrane Proteins; Mice; Mice, Inbred C57BL; Papilloma; Prostaglandin-Endoperoxide Synthases; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2002 |
Calgranulins S100A8 and S100A9 are negatively regulated by glucocorticoids in a c-Fos-dependent manner and overexpressed throughout skin carcinogenesis.
Topics: Animals; Anti-Inflammatory Agents; Antigens, Differentiation; Antineoplastic Agents, Hormonal; Calcium; Calcium-Binding Proteins; Calgranulin A; Calgranulin B; Carcinogens; Carcinoma, Squamous Cell; Dexamethasone; Disease Progression; Drug Eruptions; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, fos; Keratinocytes; Leukocytes; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Papilloma; Protein Kinase C; Proto-Oncogene Proteins c-fos; S100 Proteins; Skin Neoplasms; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2002 |
The carcinogenic effect of TPA (12-0-tetradecanoylphorbol-13-acetate) when applied to the skin of hairless mice.
Topics: Animals; Carcinoma, Squamous Cell; Fibrosarcoma; Mice; Mice, Nude; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1979 |
Transmaternal modification of the Berenblum/Mottram experiment in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Female; Fetus; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Papilloma; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1978 |
Potent tumor-initiating activity of the 3,4-dihydrodiol of 7,12-dimethylbenz(a)anthracene in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Effects of structural changes on the tumor-promoting activity of phorbol myristate acetate on mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aldehydes; Animals; Carcinoma, Squamous Cell; Decanoates; Drug Synergism; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Inhibition of phorbol ester-induced tumor promotion in mice by vitamin A analog and anti-inflammatory steroid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Drug Synergism; Female; Fluocinolone Acetonide; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitamin A | 1979 |
Life history and histopathology of ultraviolet light-induced skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Cricetinae; Female; Mice; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Papilloma; Rats; Sarcoma, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1978 |
[Skin transplantation in the study of chemical carcinogenesis. III. Reduced papilloma-formation after initiation during epidermal hyperplasia induced by skin grafting or by a single application of the cocarcinogen TPA].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Hyperplasia; Mice; Mice, Inbred C3H; Papilloma; Skin; Skin Transplantation; Tetradecanoylphorbol Acetate; Time Factors; Transplantation, Autologous | 1975 |
Phorbol as a possible systemic promoting agent for skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Synergism; Female; Injections, Intraperitoneal; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1976 |
Increased cyclic adenosine 3':5'-monophosphate phosphodiesterase activity in the epidermis of phorbol ester-treated mouse skin and in papillomas.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Colchicine; Enzyme Induction; Female; Mice; Neoplasms, Experimental; Papilloma; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vinblastine | 1979 |
Effects of 12-O-tetradecanoylphorbol-13-acetate and mezerein on epidermal ornithine decarboxylase activity, isoproterenol-stimulated levels of cyclic adenosine 3':5'-monophosphate, and induction of mouse skin tumors in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Division; Cyclic AMP; Dermatitis, Contact; Diterpenes; Female; Isoproterenol; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1979 |
Carcinogenicity of halogenated olefinic and aliphatic hydrocarbons in mice.
Topics: Animals; Carcinogens, Environmental; Cocarcinogenesis; Drug Evaluation, Preclinical; Female; Hydrocarbons, Halogenated; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Papilloma; Sarcoma, Experimental; Skin Neoplasms; Stomach Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Induction of the formation of new hair follicles in mouse tail epidermis by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Hair; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin; Skin Neoplasms; Tail; Tetradecanoylphorbol Acetate | 1977 |
Comparison of the skin tumor initiating activity of 3-methylcholanthrene and 3,11-dimethylcholanthrene in mice.
Topics: Animals; Female; Methylcholanthrene; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Skin tumor-initiating activities of the twelve isomeric phenols of benzo(a)pyrene.
Topics: Animals; Benzopyrenes; Female; Isomerism; Mice; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Time Factors | 1978 |
Tumor-promoting activity of 2,3-dihydrophorbol myristate acetate and phorbolol myristate acetate in mouse skin.
Topics: Animals; Dermatitis, Contact; Female; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1978 |
Evidence that benzo(a)anthracene 3,4-diol-1,2-epoxide is an ultimate carcinogen on mouse skin.
Topics: Animals; Benz(a)Anthracenes; Biotransformation; Carcinogens; Female; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Stereoisomerism; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1978 |
Comparative tumor initiating activity of 10-methylbenzo-[a]pyrene, 7,10-dimethylbenzo[a]pyrene and benzo[a]pyrene.
Topics: Animals; Benzopyrenes; Biotransformation; Female; Keratoacanthoma; Mice; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1978 |
Marked differences in the skin tumor-initiating activities of the optical enantiomers of the diastereomeric benzo(a)pyrene 7,8-diol-9,10-epoxides.
Topics: Animals; Benzopyrenes; Carcinogens; Epoxy Compounds; Female; Mice; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Stereoisomerism; Tetradecanoylphorbol Acetate | 1979 |
Correlation of the inhibition by retinoids of tumor promoter-induced mouse epidermal ornithine decarboxylase activity and of skin tumor promotion.
Topics: Animals; Carboxy-Lyases; Enzyme Induction; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Vitamin A | 1979 |
Inhibition of two-stage carcinogenesis in mouse skin with bis(2-chloroethyl)sulfide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinoma, Squamous Cell; Female; Mice; Mice, Inbred ICR; Mustard Compounds; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Sulfides; Tetradecanoylphorbol Acetate | 1976 |
Regression kinetics of mouse skin papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antilymphocyte Serum; Dose-Response Relationship, Drug; Female; Half-Life; Mice; Neoplasm Regression, Spontaneous; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1976 |
Transmaternal variation of the Berenblum experiment with NMRI-mice: tumour initiation with DMBA via mothers milk followed by promotion with the phorbol ester TPA.
Topics: Animals; Animals, Newborn; Benz(a)Anthracenes; Carcinoma, Squamous Cell; Female; Mice; Milk; Neoplasms, Experimental; Papilloma; Tetradecanoylphorbol Acetate | 1976 |
Epidermal cell proliferation and promoting ability of phorbol esters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Edema; Female; Hyperplasia; Inflammation; Mice; Neoplasms, Experimental; Papilloma; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1976 |
Improved tumour yields by means of a TPA-DMBA-TPA variation of the Berenrlum-Mottram experiment on the back skin of NMRI mice. The effect of stationary hyperplasia without inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinoma; Female; Hyperplasia; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1976 |
Vitamin A acid (retinoic acid), a potent inhibitor of 12-O-tetradecanoyl-phorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Drug Administration Schedule; Enzyme Induction; Female; In Vitro Techniques; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1977 |
Marked differences in the tumor-initiating activity of optically pure (+)- and (-)-trans-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene on mouse skin.
Topics: Animals; Benzopyrenes; Female; Mice; Microsomes, Liver; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Stereoisomerism; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1977 |
Skin-tumor-initiating ability of benzo(a)pyrene-7,8-diol-9,10-epoxide (anti) when applied topically in tetrahydrofuran.
Topics: Acetone; Animals; Benzene; Benzopyrenes; Carcinogens; Drug Interactions; Female; Furans; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Solvents; Stereoisomerism; Tetradecanoylphorbol Acetate | 1977 |
Comparison of the tumor-initiating activities of benzo(a)pyrene arene oxides and diol-epoxides.
Topics: Animals; Benzopyrenes; Epoxy Compounds; Female; Glycols; Mice; Neoplasms, Experimental; Oxides; Papilloma; Skin Neoplasms; Stereoisomerism; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1977 |
Tumour-initiating activities on mouse skin of dihydrodiols derived from benzo[a]pyrene.
Topics: Animals; Benzopyrenes; Carcinoma, Squamous Cell; Female; Fibrosarcoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1976 |
Acetic acid, a potent stimulator of mouse epidermal macromolecular synthesis and hyperplasia but with weak tumor-promoting ability.
Topics: Acetates; Animals; Croton Oil; Cytidine; DNA; Dose-Response Relationship, Drug; Female; Hyperplasia; Leucine; Mice; Neoplasms, Experimental; Papilloma; Proteins; RNA; Skin; Skin Neoplasms; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thymidine | 1975 |
Development of an in vitro model to study carcinogen-induced neoplastic progression of initiated mouse epidermal cells.
Topics: Animals; Animals, Newborn; Base Sequence; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Cells; Epidermis; Genes, ras; Keratinocytes; Keratins; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Oligodeoxyribonucleotides; Papilloma; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 1992 |
Dissociation of sensitivities to tumor promotion and progression in outbred and inbred SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Carcinoma, Squamous Cell; Female; Genes, ras; Keratins; Methylnitronitrosoguanidine; Mice; Mutation; Papilloma; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1992 |
Aberrant expression of the simple epithelial type II keratin 8 by mouse skin carcinomas but not papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Northern; Carcinoma, Squamous Cell; Electrophoresis, Polyacrylamide Gel; Epithelium; Female; Fluorescent Antibody Technique; Gene Expression; Genes, ras; Immunoenzyme Techniques; Keratins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mutation; Papilloma; RNA; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Transgenic overexpression of transforming growth factor alpha bypasses the need for c-Ha-ras mutations in mouse skin tumorigenesis.
Topics: Animals; Base Sequence; Disease Models, Animal; DNA, Neoplasm; Gene Amplification; Gene Expression Regulation, Neoplastic; Genes, ras; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Wounds and Injuries | 1992 |
Potent preventive action of alpha-carotene against carcinogenesis: spontaneous liver carcinogenesis and promoting stage of lung and skin carcinogenesis in mice are suppressed more effectively by alpha-carotene than by beta-carotene.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; beta Carotene; Carotenoids; Drug Screening Assays, Antitumor; Humans; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate | 1992 |
Inhibitory effect of green tea on the growth of established skin papillomas in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Catechin; Drug Screening Assays, Antitumor; Female; Flavonoids; Injections, Intraperitoneal; Mice; Papilloma; Phenols; Plant Extracts; Polymers; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate | 1992 |
Reversal of food restriction-induced inhibition of mouse skin tumor promotion by adrenalectomy.
Topics: Adrenal Glands; Adrenalectomy; Animals; Body Weight; Corticosterone; Dehydroepiandrosterone; DNA, Neoplasm; Female; Food; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1992 |
Inhibition of mouse skin tumorigenesis by dexamethasone occurs through a Ha-ras-independent mechanism.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenalectomy; Animals; Blotting, Northern; Dexamethasone; Female; Genes, ras; Mice; Papilloma; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Dietary retinoids are essential for skin papilloma formation induced by either the two-stage or the complete tumorigenesis model in female SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Diet; Diterpenes; Female; Mice; Mice, Inbred Strains; Papilloma; Retinyl Esters; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Vitamin A; Vitamin A Deficiency | 1992 |
A subpopulation of 12-O-tetradecanoylphorbol-13-acetate-induced papillomas is not inhibited by retinoic acid.
Topics: Animals; Female; Metallothionein; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1992 |
Chemoprevention of chemically induced skin tumor development by diallyl sulfide and diallyl disulfide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Allyl Compounds; Animals; Antineoplastic Agents; Body Weight; Disulfides; Garlic; Mice; Papilloma; Plants, Medicinal; Skin Neoplasms; Sulfides; Tetradecanoylphorbol Acetate | 1992 |
Modification of tumor promotion in the mouse skin by exposure to an alternating magnetic field.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Electromagnetic Fields; Female; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Enhanced papilloma formation in response to skin tumor promotion in transgenic mice overexpressing the human ornithine decarboxylase gene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Epidermis; Gene Expression; Mice; Mice, Transgenic; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Influences of sphingosine on two-stage skin tumorigenesis in Sencar mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Body Weight; Carcinoma; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Sphingosine; Tetradecanoylphorbol Acetate | 1992 |
A model for initiated mouse skin: suppression of papilloma but not carcinoma formation by normal epidermal cells in grafts on athymic nude mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Fibroblasts; Genes, fos; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Papilloma; Skin Neoplasms; Skin Transplantation; Tetradecanoylphorbol Acetate | 1992 |
Antitumor-promoting activities of hydrolyzable tannins in mouse skin.
Topics: Animals; Antineoplastic Agents; Carcinoma; Enzyme Induction; Female; Hydrogen Peroxide; Hydrolyzable Tannins; Mice; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Birth and death/differentiation rates of papillomas in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Cell Death; Cell Differentiation; Drug Administration Schedule; Likelihood Functions; Mice; Models, Biological; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Alterations in protein kinase C isozymes alpha and beta 2 in activated Ha-ras containing papillomas in the absence of an increase in diacylglycerol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Codon; Diglycerides; Female; Genes, ras; Immune Sera; Isoenzymes; Mice; Mice, Inbred Strains; Molecular Sequence Data; Mutation; Papilloma; Peptides; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Effects of dietary calcium and vitamin D3 on tumor promotion in mouse skin.
Topics: Animals; Calcium, Dietary; Cholecalciferol; Female; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Identification of a cloned sequence activated during multi-stage carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinoma, Squamous Cell; Gene Expression Regulation, Neoplastic; Keratins; Mice; Molecular Sequence Data; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Altered regulation of growth and expression of differentiation-associated keratins in benign mouse skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Division; Female; Gene Expression Regulation, Neoplastic; Keratinocytes; Keratins; Male; Mice; Mice, Hairless; Microscopy, Fluorescence; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
v-Ha-ras-induced mouse skin papillomas exhibit aberrant expression of keratin K13 as do their 7,12-dimethylbenz[a]anthracene/12-O-tetradecanoylphorbol-13-acetate -induced analogues.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Blotting, Western; Fluorescent Antibody Technique; Gene Expression; Genes, ras; Keratinocytes; Keratins; Methylation; Mice; Molecular Sequence Data; Oligonucleotides; Oncogene Protein p21(ras); Oncogene Proteins v-fos; Papilloma; RNA, Messenger; Skin Neoplasms; Skin Transplantation; Tetradecanoylphorbol Acetate | 1991 |
Prevalence of tumor prevention rather than tumor enhancement when repetitive UV radiation treatments precede initiation and promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinoma; Female; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1992 |
Comparative tumor-initiating ability of 7H-dibenzo(c,g)carbazole and dibenz(a,j)acridine in mouse skin.
Topics: Acetone; Acridines; Animals; Benzo(a)pyrene; Carbazoles; Carcinogens; Female; Mice; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part I: Quantitation of superoxide dismutase, catalase, glutathione peroxidase
Topics: Administration, Topical; Animals; Carcinoma, Squamous Cell; Catalase; Female; Glutathione Peroxidase; Mice; Mice, Inbred Strains; Oxygen; Papilloma; Phenotype; Skin; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Xanthine Dehydrogenase; Xanthine Oxidase | 1991 |
All-trans retinoic acid protects against conversion of chemically induced and ultraviolet B radiation-induced skin papillomas to carcinomas.
Topics: Animals; Carcinoma; Female; Mice; Neoplasms, Radiation-Induced; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Ultraviolet Rays | 1991 |
Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part II: Quantitation of glutathione and glutathione disulfide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Administration, Topical; Aging; Animals; Carcinoma, Squamous Cell; Epidermis; Female; Glutathione; Glutathione Disulfide; Mice; Oxidation-Reduction; Oxygen; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin papilloma by saponins.
Topics: Animals; Female; Herpesvirus 4, Human; Mice; Mice, Inbred ICR; Papilloma; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Virus Activation | 1991 |
Immunological demonstration of a calcium-unresponsive protein kinase C of the delta-type in different species and murine tissues. Predominance in epidermis.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Calcium; Carcinoma; Down-Regulation; Drosophila; Electrophoresis, Polyacrylamide Gel; Immune Sera; Immunohistochemistry; Mice; Molecular Sequence Data; Papilloma; Phosphorylation; Protein Kinase C; Skin; Species Specificity; Spleen; Tetradecanoylphorbol Acetate | 1991 |
Promoter independence as a feature of most skin papillomas in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Genes, ras; Mice; Mutation; Neoplasm Regression, Spontaneous; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
Effects of type of dietary fat on phorbol ester-elicited tumor promotion and other events in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinoma; Corn Oil; Dinoprostone; Female; Linoleic Acid; Linoleic Acids; Mice; Mice, Inbred DBA; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Influence of diet and calorie restriction on the initiation and promotion of skin carcinogenesis in the SENCAR mouse model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinoma; Cocarcinogenesis; Diet; Energy Intake; Female; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Effect of dietary arginine restriction upon ornithine and polyamine metabolism during two-stage epidermal carcinogenesis in the mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arginine; DNA; Female; Mice; Ornithine; Ornithine Decarboxylase; Papilloma; Polyamines; Putrescine; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Inhibitory effects of new types of biflavonoid-related polyphenols; lophirone A and lophiraic acid, on some tumor promoter-induced biological responses in vitro and in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrans; Cocarcinogenesis; Enzyme Activation; Female; Flavonoids; Inflammation; Male; Mice; Mice, Inbred ICR; Papilloma; Phenols; Polymers; Protein Kinase C; Rats; Rats, Inbred WKY; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Tumor progression of murine epidermal cells after treatment in vitro with 12-O-tetradecanoylphorbol-13-acetate or retinoic acid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Synergism; Mice; Mice, Inbred BALB C; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1991 |
Overlapping loss of heterozygosity by mitotic recombination on mouse chromosome 7F1-ter in skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Base Sequence; Chromosome Mapping; DNA Probes; Genotype; Globins; Heterozygote; Mice; Mice, Inbred Strains; Mitosis; Molecular Sequence Data; Oligonucleotide Probes; Papilloma; Polymerase Chain Reaction; Recombination, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
[Presence of specific mutation of Ha-ras oncogene in skin tumors of mice induced under different experimental conditions].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Codon; Female; Genes, ras; Male; Mice; Mutation; Papilloma; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Constitutively elevated levels of ornithine and polyamines in mouse epidermal papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Guanosine Triphosphate; Mice; Mice, Inbred Strains; Ornithine; Ornithine Decarboxylase; Papilloma; Polyamines; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Activation of the rasHa gene in urethane-initiated papillomas induced by protocols with high and low frequencies of malignant conversion.
Topics: 3T3 Cells; Animals; Blotting, Southern; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA, Neoplasm; Drug Interactions; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Male; Mice; Mice, Nude; Neoplasm Transplantation; Papilloma; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Urethane | 1991 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-promoted skin tumor formation in mice by 16 alpha-fluoro-5-androsten-17-one and its reversal by deoxyribonucleosides.
Topics: Androstenes; Animals; Body Weight; Deoxyribonucleosides; Drug Interactions; Female; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Carcinogenicity study of fecapentaene-12 diacetate on skin painting in SENCAR mice.
Topics: Adult; Animals; Drug Combinations; Female; Humans; Mice; Mutagens; Papilloma; Polyenes; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitamin E | 1991 |
Inhibitory effect of apigenin, a plant flavonoid, on epidermal ornithine decarboxylase and skin tumor promotion in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chamomile; Cocarcinogenesis; Dose-Response Relationship, Drug; Enzyme Induction; Epidermis; Flavonoids; Mice; Oils, Volatile; Ornithine Decarboxylase; Papilloma; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Sensitivity of subpopulations of mouse skin papillomas to malignant conversion by urethane or 4-nitroquinoline N-oxide.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Survival Analysis; Tetradecanoylphorbol Acetate; Time Factors; Urethane | 1990 |
Anti-tumor promoting action of phthalic acid mono-n-butyl ester cupric salt, a biomimetic superoxide dismutase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antineoplastic Agents; Benz(a)Anthracenes; Cells, Cultured; Dermatitis, Contact; Dibutyl Phthalate; Ear Diseases; Edema; Enzyme Induction; Epidermal Cells; Epidermis; Female; Mice; Ornithine Decarboxylase; Papilloma; Phthalic Acids; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1990 |
Effects of beta-carotene on chemically-induced skin tumors in HRA/Skh hairless mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Carotene; Body Weight; Carotenoids; Diet; Female; Mice; Mice, Hairless; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Effects of antihistamines on phorbol ester tumor promotion and vascular permeability changes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Capillary Permeability; Cimetidine; Diphenhydramine; Female; Indomethacin; Inflammation; Masoprocol; Mice; Mice, Inbred Strains; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
S/RV Cri-ba, a hairless mouse strain sensitive to skin tumorigenesis by suboptimal doses of 7,12-dimethylbenz[a]anthracene, initiation-promotion and two stage promotion protocols.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Cocarcinogenesis; Diterpenes; Dose-Response Relationship, Drug; Female; Mice; Mice, Hairless; Papilloma; Phorbol Esters; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1990 |
Papilloma and carcinoma production in DMBA-initiated, onion oil-promoted mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Allium; Animals; Carcinoma; Cell Transformation, Neoplastic; Female; Garlic; Mice; Papilloma; Plant Oils; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Increased sensitivity to two-stage skin carcinogenesis of mice heterozygous for the repeated epilation mutation (Er).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Hair Removal; Heterozygote; Male; Mice; Mice, Inbred BALB C; Mutation; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Elevated expression of secondary, but not early, responding genes to phorbol ester tumor promoters in papillomas and carcinomas of mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Northern; Carcinogens; Carcinoma; Female; Gene Expression; Metallothionein; Methylnitronitrosoguanidine; Mice; Mice, Inbred Strains; Osteopontin; Papilloma; Proto-Oncogene Proteins; RNA, Messenger; Sialoglycoproteins; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Transforming Growth Factors; Tubulin; Urokinase-Type Plasminogen Activator | 1990 |
Evidence that weak promotion of carcinogen-initiated cells prevents their progression to malignancy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoflavones; Benzyl Alcohols; Cell Transformation, Neoplastic; Cortisone; Dose-Response Relationship, Drug; Indoles; Mice; Mice, Inbred BALB C; Papilloma; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin E | 1990 |
Nicotinamide and nicotinamide analogues as antitumor promoters in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminobenzoates; Animals; Antineoplastic Agents; Benzamides; Benzoates; Benzoic Acid; Cell Division; Clone Cells; DNA Replication; Female; Keratinocytes; Kinetics; meta-Aminobenzoates; Mice; Mice, Inbred Strains; Niacinamide; Papilloma; Poly(ADP-ribose) Polymerase Inhibitors; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Absence of papillomavirus in skin tumors induced in SENCAR mice by a two-stage carcinogenesis protocol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; DNA, Viral; Female; Mice; Papilloma; Papillomaviridae; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Antitumor-promoting activity of sesquiterpene isolated from an herbal spice.
Topics: Aldehydes; Animals; Condiments; Herpesvirus 4, Human; Humans; Japan; Mice; Papilloma; Sesquiterpenes; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virus Activation | 1990 |
Inhibition of mouse skin tumor promotion by adriamycin and daunomycin in combination with verapamil or palmitoylcarnitine.
Topics: Animals; Daunorubicin; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Enzyme Induction; Female; Mice; Ornithine Decarboxylase; Palmitoylcarnitine; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Verapamil | 1990 |
Identification of epidermal cell subpopulations with increased ornithine decarboxylase activity following treatment of murine epidermis with 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cells, Cultured; Epidermal Cells; Epidermis; Female; Flow Cytometry; Mice; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Differential down-regulation of epidermal protein kinase C by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol: association with epidermal hyperplasia and tumor promotion.
Topics: Acetone; Animals; Diglycerides; Down-Regulation; Female; Glycerides; Hyperplasia; Mice; Papilloma; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Keratin gene expression in mouse skin tumors and in mouse skin treated with 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Carcinoma; Female; Fluocinolone Acetonide; Gene Expression Regulation; Keratins; Mice; Molecular Weight; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1985 |
Induction of papillomas with a high probability of conversion to malignancy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Diterpenes; DNA; Female; Keratins; Mice; Mice, Inbred Strains; Papilloma; Probability; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Heterogeneity of ornithine decarboxylase expression in 12-O-tetradecanoylphorbol-13-acetate-treated mouse skin and in epidermal tumors.
Topics: Animals; Enzyme Induction; Epidermal Cells; Epidermis; Female; Keratins; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Elevated expression of Ha-ras is an early event in two-stage skin carcinogenesis in SENCAR mice.
Topics: Animals; Female; Gene Amplification; Mice; Mice, Inbred Strains; Nucleic Acid Hybridization; Papilloma; Poly A; Proto-Oncogenes; RNA; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Carcinoma; Cell Transformation, Neoplastic; Female; Gene Expression Regulation; Genes; Keratins; Mice; Mice, Inbred Strains; Nucleic Acid Hybridization; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1988 |
Sequential development of aneuploidy, keratin modifications, and gamma-glutamyltransferase expression in mouse skin papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; gamma-Glutamyltransferase; Immunoenzyme Techniques; Keratins; Metaphase; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
Dietary fat effects on the initiation and promotion of two-stage skin tumorigenesis in the SENCAR mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Dietary Fats; Energy Intake; Female; Genes, ras; Mice; Papilloma; RNA; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Induction of terminal differentiation-resistant epidermal cells in mouse skin and in papillomas by different initiators during two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Epidermal Cells; Female; Methylnitronitrosoguanidine; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Tumor copromoting activity of gamma-interferon in the murine skin multistage carcinogenesis model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Female; Interferon-gamma; Mice; Papilloma; Recombinant Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Tumor prevention by a xanthate compound in experimental mouse-skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Antineoplastic Agents; Antiviral Agents; Bridged-Ring Compounds; Carcinoma; Dose-Response Relationship, Drug; Female; Mice; Norbornanes; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones | 1989 |
Dose and frequency effect in mouse skin tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dose-Response Relationship, Drug; Female; Mice; Papilloma; Skin Neoplasms; Statistics as Topic; Tetradecanoylphorbol Acetate | 1989 |
Further characterization of skin tumor promotion and progression by mezerein in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Diterpenes; DNA; Female; Mice; Papilloma; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Acceleration of papilloma growth in mice fed high-fat diets during promotion of two-stage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Cocarcinogenesis; Dietary Fats; Female; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Sodium o-phenylphenate (OPP-Na) promotes skin carcinogenesis in CD-1 female mice initiated with 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biphenyl Compounds; Carcinoma; Drug Synergism; Female; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Effects of oral versus topical administration of cyclosporine on phorbol ester promotion of murine epidermal carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, Topical; Animals; Carcinoma, Squamous Cell; Cyclosporins; Hyperplasia; Male; Mice; Neutrophils; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Regulation of ornithine decarboxylase in normal and neoplastic mouse and human epidermis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Chromatography, Gel; Epidermis; Female; Humans; Kinetics; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Malignant conversion of UV radiation and chemically induced mouse skin benign tumors by free-radical-generating compounds.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Amidines; Animals; Benzoyl Peroxide; Carcinogens; Cell Transformation, Neoplastic; Female; Free Radicals; Mice; Mice, Hairless; Mice, Inbred Strains; Neoplasms, Radiation-Induced; Papilloma; Peroxides; Skin; Skin Diseases; Skin Neoplasms; tert-Butylhydroperoxide; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1989 |
Comparison of octahydromezerein and mezerein as protein kinase C activators and as mouse skin tumor promoters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Diterpenes; Enzyme Activation; Female; Hyperplasia; Mice; Mice, Inbred Strains; Papilloma; Protein Kinase C; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Tumor associated proteins of rat skin tumor induced by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Surface; Carcinoma, Squamous Cell; Cell Membrane; Glycoproteins; Membrane Proteins; Papilloma; Rats; Rats, Inbred Strains; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Inhibition of 7,12-dimethylbenz[a]anthracene-initiated and 12-O-tetradecanoylphorbol-13-acetate-promoted skin papilloma formation in mice by dehydroepiandrosterone and two synthetic analogs.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Body Weight; Dehydroepiandrosterone; Female; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1989 |
Induction of metallothionein mRNA by tumor promoters in mouse skin and its constitutive expression in papillomas.
Topics: Administration, Topical; Animals; Carcinogens; Cholecalciferol; Female; Gene Expression Regulation; Metallothionein; Mice; Mice, Inbred C57BL; Papilloma; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin | 1989 |
[Anti-tumor promoting activities and inhibitory effects on Epstein-Barr virus activation of Shi-un-kou and its constituents].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Depression, Chemical; Drugs, Chinese Herbal; Female; Herpesvirus 4, Human; Mice; Mice, Inbred ICR; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Virus Activation | 1989 |
Activation of the cellular Harvey ras gene in mouse skin tumors initiated with urethane.
Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Codon; DNA Probes; Gene Amplification; Genes, ras; Mice; Mutation; Papilloma; Polymorphism, Restriction Fragment Length; Proto-Oncogene Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Stem Cell Assay; Urethane | 1989 |
Detection of distinct transforming genes in X-ray induced tumors.
Topics: Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Mice; Mice, Inbred Strains; Neoplasms, Radiation-Induced; Oncogenes; Papilloma; Restriction Mapping; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; X-Rays | 1989 |
Mouse skin papillomas as a stage in cancer progression.
Topics: Animals; Benzo(a)pyrene; Cell Division; Cocarcinogenesis; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Correlation of phorbol ester promotion in the resistant C57BL/6J mouse with sustained hyperplasia but not ornithine decarboxylase or protein kinase C.
Topics: Animals; Carcinoma; Enzyme Induction; Hyperplasia; Mice; Mice, Inbred C57BL; Ornithine Decarboxylase; Papilloma; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Analysis of the rasH oncogene and its p21 product in chemically induced skin tumors and tumor-derived cell lines.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Line; Deoxyribonucleases, Type II Site-Specific; DNA Restriction Enzymes; DNA, Neoplasm; Female; Mice; Oncogenes; Papilloma; Polymorphism, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 1987 |
Sequential study of gamma-glutamyltransferase during complete and two-stage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Female; gamma-Glutamyltransferase; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Malignant progression of mouse skin papillomas treated with ethylnitrosourea, N-methyl-N'-nitro-N-nitrosoguanidine, or 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ethylnitrosourea; Female; gamma-Glutamyltransferase; Methylnitronitrosoguanidine; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Cultivation and characterization of cells derived from mouse skin papillomas induced by an initiation-promotion protocol.
Topics: Animals; Calcium; Cell Differentiation; Cell Division; Cells, Cultured; Cocarcinogenesis; Culture Media; Epidermal Cells; Female; Mice; Mice, Inbred Strains; Mice, Nude; Neoplasm Transplantation; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thymidine; Transglutaminases | 1986 |
Transplacental induction of a specific mutation in fetal Ha-ras and its critical role in post-natal carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinoma; Cocarcinogenesis; DNA, Neoplasm; Female; Mice; Mutation; Papilloma; Polymorphism, Restriction Fragment Length; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Proto-Oncogenes; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Eicosanoids and multistage carcinogenesis in NMRI mouse skin: role of prostaglandins E and F in conversion (first stage of tumor promotion) and promotion (second stage of tumor promotion).
Topics: Animals; Cocarcinogenesis; Dinoprost; Dinoprostone; Epidermis; Indomethacin; Mice; Papilloma; Phorbol Esters; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
v-ras genes from Harvey and BALB murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis.
Topics: Animals; Carcinoma; Clone Cells; Cocarcinogenesis; Genes, Viral; Harvey murine sarcoma virus; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Oncogene Protein p21(ras); Oncogenes; Papilloma; RNA, Messenger; RNA, Neoplasm; RNA, Viral; Sarcoma Viruses, Murine; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced epidermal ornithine decarboxylase activity and tumor promotion by N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) in mouse skin.
Topics: Animals; Calcium; Calmodulin; Enzyme Induction; Female; Lyngbya Toxins; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Papilloma; Phorbols; Protein Kinase C; Skin; Skin Neoplasms; Sulfonamides; Tetradecanoylphorbol Acetate | 1986 |
[Factors controlling tumor promotion induced by TPA].
Topics: Animals; Benzoquinones; Enzyme Activation; Lipoxygenase Inhibitors; Mice; Ornithine Decarboxylase; Palmitoylcarnitine; Papilloma; Phorbols; Phospholipases; Phospholipases A; Phospholipases A2; Protein Kinase C; Quinones; Skin Neoplasms; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1986 |
Enhanced malignant progression of mouse skin tumors by the free-radical generator benzoyl peroxide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Cocarcinogenesis; Female; Free Radicals; Keratoacanthoma; Mice; Mice, Inbred Strains; Papilloma; Peroxides; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Modulation of mouse skin tumor promotion by dietary 13-cis-retinoic acid and alpha-difluoromethylornithine.
Topics: Animals; Diet; Eflornithine; Female; Isotretinoin; Mice; Mice, Inbred Strains; Ornithine; Ornithine Decarboxylase; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Inhibition of the prenatal dimethylbenz[a]anthracene-induced tumour initiation in mice by prior administration of 7,8-benzoflavone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Administration, Oral; Animals; Benzoflavones; Cocarcinogenesis; Female; Flavonoids; Lung Neoplasms; Mice; Neoplasms, Experimental; Papilloma; Pregnancy; Prenatal Exposure Delayed Effects; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Hyperthermia and phorbol ester tumor promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Female; Hyperthermia, Induced; Mice; Papilloma; Phorbols; Skin; Skin Neoplasms; Skin Temperature; Tetradecanoylphorbol Acetate | 1986 |
Cell-mediated immune response in mice during the two-step carcinogenesis experiment by 7,12-dimethylbenz(a)anthracene and 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens; Dinitrofluorobenzene; Erythrocytes; Female; Hypersensitivity, Delayed; Immunity, Cellular; Mice; Mice, Inbred ICR; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Sebaceous adenomas with associated epidermal hyperplasia and papilloma formation as a major type of tumor induced in mouse skin by high doses of carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Carcinoma; Epidermis; Hyperplasia; Mice; Mice, Nude; Papilloma; Sebaceous Gland Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Sequential studies of skin tumorigenesis in phosphoglycerate kinase mosaic mice: effect of resumption of promotion on regressed papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Mice; Mice, Inbred BALB C; Mosaicism; Papilloma; Phosphoglycerate Kinase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Progressive dysplasia and aneuploidy are hallmarks of mouse skin papillomas: relevance to malignancy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Carcinoma, Squamous Cell; Cell Nucleus; Mice; Mice, Inbred Strains; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Characterization of skin tumor promotion and progression by chrysarobin in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
A novel system for studying in vivo effects of tumor promoters on DNA tumor viruses.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Cocarcinogenesis; Cricetinae; DNA Tumor Viruses; DNA, Viral; Drug Interactions; Male; Mesocricetus; Papilloma; Papillomaviridae; Polyomaviridae; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Sequential studies of skin tumorigenesis in PGK mosaic mice: the effect of repeated exposure to a carcinogen on regressed mouse skin papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Interactions; Mice; Mice, Inbred BALB C; Mosaicism; Papilloma; Phenotype; Phosphoglycerate Kinase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Elevated expression and point mutation of the Ha-ras proto-oncogene in mouse skin tumors promoted by benzoyl peroxide and other promoting agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Female; Gene Expression Regulation; Mice; Mutation; Papilloma; Peroxides; Proto-Oncogenes; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Differentiating among proposed mechanisms for tumor promotion in mouse skin with the use of the multievent model for cancer.
Topics: 4-Nitroquinoline-1-oxide; Acetone; Animals; Cell Transformation, Neoplastic; Mathematics; Mice; Models, Biological; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urethane | 1987 |
Development of murine epidermal cell lines which contain an activated rasHa oncogene and form papillomas in skin grafts on athymic nude mouse hosts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Calcium; Cell Line; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Oncogenes; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 1988 |
Inhibition of mouse skin tumor promotion and of promoter-induced epidermal polyamine biosynthesis by methylglyoxal bis(butylamidinohydrazone).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Male; Mice; Mice, Inbred Strains; Mitoguazone; Ornithine Decarboxylase Inhibitors; Papilloma; Polyamines; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
The influence of a hyperthermia treatment on chemically induced tumor initiation and progression in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; DNA Repair; Female; Glutathione; Hyperthermia, Induced; Methylnitronitrosoguanidine; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
Enhancement of mezerein-promoted papilloma formation by treatment with 12-O-tetradecanoylphorbol-13-acetate or mezerein prior to initiation.
Topics: Animals; Calcimycin; Diterpenes; Drug Synergism; Female; Hyperplasia; Mice; Papilloma; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1988 |
Influence of dose of initiator on two-stage skin carcinogenesis in BALB/c mice with cellular mosaicism.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred BALB C; Mosaicism; Papilloma; Phenotype; Phosphoglycerate Kinase; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1988 |
Comparison of the inhibitory effects of retinoids on 12-O-tetradecanoylphorbol-13-acetate-promoted tumor formation in CD-1 and Sencar mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Female; Mice; Mice, Inbred Strains; Papilloma; Retinoids; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1988 |
Sensitivity of HRA/Skh hairless mice to initiation/promotion of skin tumors by chemical treatment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Dose-Response Relationship, Drug; Mice; Mice, Hairless; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
Modulation of chrysarobin skin tumor promotion.
Topics: Animals; Anthracenes; Carcinogens; Cocarcinogenesis; Eflornithine; Female; Fluocinolone Acetonide; Mice; Ornithine Decarboxylase; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1988 |
Sensitivity of the skin of different mouse strains to the promoting effect of 12-0-tetradecanoyl-phorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Disease Susceptibility; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Papilloma; Skin; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1988 |
Tumor progression in Sencar mouse skin as a function of initiator dose and promoter dose, duration, and type.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Carcinogens; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Female; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
Expression pattern of a gene for a secreted metalloproteinase during late stages of tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Carcinoma, Squamous Cell; Cloning, Molecular; DNA, Neoplasm; Female; Gene Amplification; Gene Rearrangement; Immunoblotting; Matrix Metalloproteinase 3; Metalloendopeptidases; Mice; Molecular Sequence Data; Multigene Family; Neoplasm Proteins; Papilloma; Peptide Hydrolases; Plasmids; RNA, Neoplasm; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
Effects of TPA dose variation and mezerein on skin tumorigenesis by initiation promotion protocol in S/RV Cri mice.
Topics: Animals; Carcinogens; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Female; Mice; Papilloma; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1988 |
Ornithine decarboxylase from mouse epidermis and epidermal papillomas: differences in enzymatic properties and structure.
Topics: Animals; Epidermis; Hot Temperature; Isoelectric Point; Kinetics; Mice; Molecular Weight; Nucleotides; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Effects of dietary retinyl palmitate or 13-cis-retinoic acid on the promotion of tumors in mouse skin.
Topics: Administration, Cutaneous; Animals; Cell Transformation, Neoplastic; Diet; Diterpenes; Dose-Response Relationship, Drug; Female; Isotretinoin; Mice; Papilloma; Retinyl Esters; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Vitamin A | 1987 |
Enhancement of esophageal carcinogenesis induced in rats by N-amyl-N-methylnitrosamine in the presence of 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Body Weight; Carcinogens; Carcinoma in Situ; Esophageal Neoplasms; Male; Nitrosamines; Papilloma; Precancerous Conditions; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
The mRNA coding for the secreted protease transin is expressed more abundantly in malignant than in benign tumors.
Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Viral; Endopeptidases; Gene Expression Regulation; Matrix Metalloproteinase 3; Mice; Neoplasm Proteins; Neoplasms, Experimental; Papilloma; RNA, Messenger; RNA, Neoplasm; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Tumour initiating activity of mancozeb--a carbamate fungicide in mouse skin.
Topics: Animals; Carcinogens; Female; Maneb; Mice; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thiocarbamates; Zineb | 1987 |
Ionizing radiation enhances malignant progression of mouse skin tumors.
Topics: Acetone; Animals; Carcinoma; Cocarcinogenesis; Female; Methylnitronitrosoguanidine; Mice; Neoplasms, Radiation-Induced; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Mechanism of mouse skin tumor promotion by n-dodecane.
Topics: Acetone; Alkanes; Animals; Cocarcinogenesis; Diterpenes; Female; Mice; Papilloma; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
Ionizing radiation as an initiator in the mouse two-stage model of skin tumor formation.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Female; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; X-Rays | 1986 |
Effect of application frequency on epidermal ornithine decarboxylase induction by chrysarobin in SENCAR mice.
Topics: Animals; Anthracenes; Carcinogens; Drug Administration Schedule; Enzyme Induction; Female; Mice; Ornithine Decarboxylase; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Association of carcinoma yield with early papilloma development in SENCAR mice.
Topics: Animals; Carcinogens; Carcinoma; Cocarcinogenesis; Disease Models, Animal; Drug Evaluation, Preclinical; False Negative Reactions; Female; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Comparison of the tumorigenic response of SENCAR and C57BL/6 mice to benzo(a)pyrene and the inter-experimental variability over a three-year period.
Topics: Animals; Benzo(a)pyrene; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1986 |
Studies of skin tumorigenesis in PGK mosaic mice: many promoter-independent papillomas and carcinomas do not develop from pre-existing promoter-dependent papillomas.
Topics: Animals; Biopsy; Carcinoma; Mice; Mice, Inbred BALB C; Mosaicism; Papilloma; Phenotype; Phosphoglycerate Kinase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Papilloma development on young and senescent mouse skin treated with 12-O-tetradecanoylphorbol 13-acetate.
Topics: Aging; Animals; Hyperplasia; Mice; Mice, Inbred BALB C; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
Enhancement of two-stage skin carcinogenesis by exposure of distant skin to UV radiation.
Topics: Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Female; Fibrosarcoma; Immune Tolerance; Mice; Mice, Inbred C3H; Neoplasms, Radiation-Induced; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Ultraviolet Rays | 1985 |
Effects of short-term exposure to the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate on skin carcinogenesis in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Female; Mice; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
Proto-oncogene expression during two-stage carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Female; Gene Expression Regulation; Mice; Oncogenes; Papilloma; RNA, Neoplasm; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
Two-stage tumor promotion in mouse skin: an alternative interpretation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Croton Oil; Fluocinolone Acetonide; Mice; Mice, Inbred Strains; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tosylphenylalanyl Chloromethyl Ketone; Tretinoin | 1985 |
Soft agar colony formation of mouse epidermal cells during the early phase of two-stage chemically induced carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Agar; Animals; Cocarcinogenesis; Colony-Forming Units Assay; Epidermis; Male; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Stem Cell Assay | 1985 |
12-O-tetradecanoylphorbol-13-acetate promotes tumors prior to initiation in two-stage promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Diterpenes; Enzyme Induction; Female; Mice; Models, Biological; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Papilloma; Phorbols; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Tumor promoter-induced refractory state against ornithine decarboxylase induction by 12-O-tetradecanoylphorbol-13-acetate in mouse epidermis.
Topics: Acetone; Alkynes; Animals; Carcinogens; Cycloheximide; Diterpenes; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Induction; Epidermis; Female; Mice; Ornithine Decarboxylase; Papilloma; Phorbols; Terpenes; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Mechanism of mouse skin tumor promotion by chrysarobin.
Topics: Animals; Anthracenes; Anthralin; Carcinogens; Dose-Response Relationship, Drug; Edema; Female; Hyperplasia; Mice; Ornithine Decarboxylase; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
Dermal collagen metabolism during tumor promotion with 12-O-tetradecanoylphorbol-13-acetate in mouse skin.
Topics: Animals; Collagen; Female; Hydroxyproline; Methylcholanthrene; Mice; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
Cisplatin as an initiating agent in two-stage mouse skin carcinogenesis.
Topics: Animals; Carcinogens; Cisplatin; Cocarcinogenesis; Female; Injections, Intraperitoneal; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Urethane | 1985 |
Promotion of epidermal carcinogenesis by repeated damage to mouse skin.
Topics: Age Factors; Animals; Carcinogens; Female; Hyperplasia; Mice; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1985 |