tetradecanoylphorbol acetate has been researched along with Osteosarcoma in 77 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (23.38) | 18.7374 |
| 1990's | 44 (57.14) | 18.2507 |
| 2000's | 14 (18.18) | 29.6817 |
| 2010's | 1 (1.30) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kimura, Y; Sumiyoshi, M | 1 |
| Halttunen, T; Hanemaaijer, R; Heikkilä, P; Hirn, MY; Konttinen, YT; Laitinen, M; Moilanen, M; Salo, T; Sorsa, T; Teronen, O; Tervahartiala, T | 1 |
| Aicher, WK; George, M; Müller, O; Pap, T; Parak, WJ; Stein, B; Weis-Klemm, M | 1 |
| Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW | 1 |
| Bansal, AK; Mantovani, R; Sodek, J; Su, M | 1 |
| Alvarez, M; Bidwell, JP; Charoonpatrapong, K; Chen, S; Clapp, DW; Kopp, RP; Pavalko, FM; Robling, AG; Shah, R; Yu, J | 1 |
| Chang, HC; Chen, IS; Cheng, HH; Chi, CC; Chu, ST; Ho, CM; Hsu, SS; Huang, CJ; Huang, JK; Jan, CR; Liu, SI; Lu, YC; Su, HH; Wang, JL | 1 |
| Connors, WL; Heino, J; Johnson, MS; Jokinen, J; Kankaanpää, P; Puranen, JS; Tulla, M; Upla, P; White, DJ | 1 |
| Guo, QN; Li, Y; Meng, G | 1 |
| Shupnik, MA; Tashjian, AH | 1 |
| Dexter, TM; Lanotte, M; Shah, G | 1 |
| Brugmans, M; Cassiman, JJ; De Martelaere, D; Van den Berghe, H | 1 |
| Blumberg, PM; Jaken, S; Shupnik, MA; Tashjian, AH | 1 |
| Azarani, A; Goltzman, D; Orlowski, J | 1 |
| Azzi, A; Boscoboinik, D; Galeotti, T | 1 |
| Aletta, JM; Dziak, RM; Zhang, W | 1 |
| Fujimura, S; Kato, N; Miya, T; Sato, K; Tagawa, M; Takahashi, K | 1 |
| Abou-Samra, AB; Bergwitz, C; Hesch, RD; Jüppner, H | 1 |
| Akerman, KE; Jäntti, J; Ringbom-Anderson, T | 1 |
| Chihara, K; Fukase, M; Kano, J; Sugimoto, T; Yamaguchi, T | 1 |
| Arao, M; Chihara, K; Fukase, M; Sugimoto, T; Yamaguchi, T | 1 |
| Alford, GE; Babich, M; Nissenson, RA | 1 |
| Fox, WM; Korach, KS; Migliaccio, S; Washburn, TF; Wetsel, WC | 1 |
| Rao, LG; Wylie, JN | 1 |
| Chihara, K; Fukase, M; Kano, J; Sugimoto, T | 2 |
| Chihara, K; Fukase, M; Kaji, H; Kanatani, M; Sugimoto, T | 1 |
| Casati, G; Gambetta, RA; Perego, P; Soranzo, C; Zunino, F | 1 |
| Moran, D; Rogalsky, V; Todorov, G | 1 |
| Brachet, P; Dicou, E; Harvie, D; Jehan, F; Naveilhan, P; Neveu, I; Wion, D | 1 |
| Chik, CL; Ho, AK; Karpinski, E; Li, B; Taniguchi, N | 1 |
| Christopoulos, G; Findlay, DM; Houssami, S; Sexton, PM | 1 |
| Bourgoin, SG; Harbour, D; Poubelle, PE | 1 |
| Hruska, K; Onishi, T | 1 |
| Clohisy, JC; Cook, TF; Koe, RC; Partridge, NC; Pulumati, MR; Tyson, DR | 1 |
| Cikós, T; Kalthoff, H; Krull, NB; Ungefroren, H | 1 |
| Arnold, D; Bidwell, J; Hock, JM; Libermann, TA; McClelland, P; Onyia, JE; Tu, Y | 1 |
| Horst, RL; Reinhardt, TA | 1 |
| Howard, GA; Roos, BA; Schiller, PC | 1 |
| Min, YK; Okada, Y; Pilbeam, CC; Raisz, LG; Rao, Y | 1 |
| Heino, J; Kähäri, VM; Koivisto, L; Nissinen, L; Westermarck, J | 1 |
| Bruland, OS; Bucht, E; Gautvik, KM; Haug, E; Jemtland, R; Olstad, OK; Rian, E | 1 |
| Belinsky, GS; Tashjian, AH | 1 |
| Adema, GJ; Figdor, CG; Nelissen, JM; Pluyter, M; Raymakers, RA; Torensma, R; van Kooyk, Y | 1 |
| Gomez, P; Himpens, B; Vereecke, J | 1 |
| Bliziotes, MM; Eshleman, AJ; Wiren, KM; Zhang, XW | 1 |
| Alexandre, D; Chada, S; Chen, Y; Christiansen, KA; Fisher, PB; Goldstein, NI; Gopalkrishnan, RV; Huang, EY; Huberman, E; Jiang, H; Kang, D; Lebedeva, IV; Leszczyniecka, M; Lin, JJ; Madireddi, MT; Mei, MX; Mhashilkar, AB; Pestka, S; Sivo, F; Su, Z; Vozhilla, N | 1 |
| Albrecht, RM; Bertics, PJ; Mellon, WS; Mosavin, R; Rivera-Bermúdez, MA | 1 |
| Green, J; Kleeman, CR; Merritt, BS; Muallem, S; Yamaguchi, DT | 1 |
| Fang, MA; Hahn, TJ; Kujubu, DA | 1 |
| Gelderblom, D; Hough, S; Koch, HM; Muir, H | 1 |
| Kumar, S; Rani, AS | 1 |
| Akerman, KE; Ringbom-Anderson, T | 1 |
| Fujita, T; Fukase, M; Ikeda, K; Sugimoto, T | 1 |
| Dziak, R; Hagel-Bradway, S; Tatakis, DN | 1 |
| Ransjö, M | 1 |
| Khademazad, M; Loessberg, P; Muallem, S; Whisenant, N; Zhang, BX | 1 |
| Avioli, LV; Cheng, SL; Civitelli, R; Fujimori, A | 1 |
| Chakravarthy, B; Durkin, JP; Gagnon, L; Isaacs, RJ; Jouishomme, H; MacLean, S; Neugebauer, W; Rixon, RH; Whitfield, JF; Willick, G | 1 |
| Butler, WT; Kasugai, S; Overall, CM; Sodek, J; Wrana, JL; Zhang, Q | 1 |
| Alford, GE; Babich, M; Choi, H; Johnson, RM; King, KL; Nissenson, RA | 1 |
| Bidwell, JP; Carter, WB; Fryer, MJ; Heath, H | 1 |
| Brown, BL; Dobson, PR; Martin, TJ; Michelangeli, VP; Moseley, JM; Russell, RG; Short, AD | 1 |
| Pines, M; Santora, A; Spiegel, A | 1 |
| Kleeman, CR; Muallem, S; Yamaguchi, DT | 1 |
| Borst, SE; Catherwood, BD | 1 |
| Freed, E; Gailit, J; Hunter, T; Ruoslahti, E; van der Geer, P | 1 |
| Murray, TM; Rao, LG | 1 |
| Abou-Samra, AB; Jueppner, H; Potts, JT; Segre, GV; Westerberg, D | 1 |
| Avioli, LV; Civitelli, R; Hruska, KA; Jeffrey, JJ; Kahn, AJ; Partridge, NC | 1 |
| Ianacone, J; Rodan, GA; Rodan, SB; Thiede, MA; Wesolowski, G | 1 |
| Di Padova, FE; Elford, P; Feyen, JH; Trechsel, U | 1 |
| Müller, R | 1 |
| Baba, H; Fujimi, T; Fujita, T; Fukase, M; Kinoshita, Y; Yamaguchi, T | 1 |
| Krug, E; Tashjian, AH | 1 |
| Biemann, HP; Krug, E; Tashjian, AH | 1 |
| Blumberg, PM; Kochenburger, RJ; Little, JB; Lovett, DR; Nagasawa, H; Schmit, A; Weichselbaum, RR | 1 |
1 review(s) available for tetradecanoylphorbol acetate and Osteosarcoma
| Article | Year |
|---|---|
Cellular and viral fos genes: structure, regulation of expression and biological properties of their encoded products.
Topics: Amino Acid Sequence; Animals; Base Sequence; Bone Neoplasms; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Fibroblasts; Gene Expression Regulation; Gene Products, gag; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Male; Mice; Oncogenes; Osteosarcoma; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; Rats; Retroviridae Proteins; Sarcoma Viruses, Murine; Teratoma; Tetradecanoylphorbol Acetate | 1986 |
76 other study(ies) available for tetradecanoylphorbol acetate and Osteosarcoma
| Article | Year |
|---|---|
Antitumor and antimetastatic actions of dihydroxycoumarins (esculetin or fraxetin) through the inhibition of M2 macrophage differentiation in tumor-associated macrophages and/or G1 arrest in tumor cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Body Weight; Cell Differentiation; Cell Line, Tumor; Cell Polarity; Cell Proliferation; Chemokine CCL2; Coumarins; Cyclin-Dependent Kinase 4; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Interleukin-10; Macrophage Activation; Macrophages; Male; Matrix Metalloproteinase 2; Mice; Neoplasm Metastasis; Osteosarcoma; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1; Umbelliferones; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2015 |
Inhibition of matrix metalloproteinase-14 in osteosarcoma cells by clodronate.
Topics: Binding Sites; Blotting, Northern; Clodronic Acid; Collagenases; Culture Media, Conditioned; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; Fluorescent Antibody Technique; Gelatinases; Humans; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Osteosarcoma; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2003 |
Metabolic activation stimulates acid secretion and expression of matrix degrading proteases in human osteoblasts.
Topics: Biotransformation; Bone Matrix; Cells, Cultured; Dose-Response Relationship, Drug; Endopeptidases; Humans; Hydrogen-Ion Concentration; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Osteoblasts; Osteosarcoma; Protons; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2004 |
Antitumor effect of nutrient synergy on human osteosarcoma cells U-2OS, MNNG-HOS and Ewing's sarcoma SK-ES.1.
Topics: Arginine; Ascorbic Acid; Bone Neoplasms; Catechin; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Lysine; Matrix Metalloproteinases; Neovascularization, Pathologic; Nutritional Physiological Phenomena; Osteosarcoma; Proline; Sarcoma, Ewing; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2005 |
Recruitment of nuclear factor Y to the inverted CCAAT element (ICE) by c-Jun and E1A stimulates basal transcription of the bone sialoprotein gene in osteosarcoma cells.
Topics: Animals; Base Sequence; Blotting, Northern; Bone and Bones; Bone Marrow Cells; CCAAT-Binding Factor; Cell Line; Cell Line, Tumor; Chromatin Immunoprecipitation; DNA Fragmentation; DNA Primers; E1A-Associated p300 Protein; Enhancer Elements, Genetic; Gene Expression Regulation, Neoplastic; Genes, Dominant; Genes, Reporter; Genetic Vectors; Histone Acetyltransferases; Histones; Hydroxamic Acids; Integrin-Binding Sialoprotein; Molecular Sequence Data; Mutation; Osteosarcoma; p300-CBP Transcription Factors; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Rats; Recombinant Fusion Proteins; Sialoglycoproteins; Stromal Cells; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factors; Transcription, Genetic; Transfection | 2005 |
HMGB1 expression and release by bone cells.
Topics: Alkaline Phosphatase; Animals; Animals, Newborn; Bone and Bones; Bone Marrow Cells; Cell Line; Cell Line, Tumor; Cell Nucleus; Colforsin; Dose-Response Relationship, Drug; HMGB1 Protein; Macrophages; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Osteosarcoma; Parathyroid Hormone; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 2006 |
Phospholipase A2-independent Ca2+ entry and subsequent apoptosis induced by melittin in human MG63 osteosarcoma cells.
Topics: Apoptosis; Calcium; Calcium Channels, L-Type; Cell Line, Tumor; Cell Survival; Egtazic Acid; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Humans; Indoles; Maleimides; Melitten; Osteoblasts; Osteosarcoma; Phospholipases A; Phospholipases A2; Tetradecanoylphorbol Acetate | 2007 |
Two synergistic activation mechanisms of alpha2beta1 integrin-mediated collagen binding.
Topics: Animals; Bone Neoplasms; Carcinogens; Cell Adhesion; CHO Cells; Collagen Type I; Cricetinae; Cricetulus; Extracellular Matrix; Humans; Integrin alpha2beta1; Ligands; Mutation; Osteosarcoma; Protein Binding; Protein Conformation; Protein Kinase C; Receptors, Collagen; Tetradecanoylphorbol Acetate | 2007 |
Changes in genomic imprinting and gene expression associated with transformation in a model of human osteosarcoma.
Topics: Bone Neoplasms; Carcinogens; Cell Line; Cell Transformation, Neoplastic; DNA Methylation; Gene Expression Regulation, Neoplastic; Genomic Imprinting; Humans; Methylnitronitrosoguanidine; Oligonucleotide Array Sequence Analysis; Osteoblasts; Osteosarcoma; Tetradecanoylphorbol Acetate | 2008 |
Epidermal growth factor and phorbol ester actions on human osteosarcoma cells. Characterization of response and nonresponsive cell lines.
Topics: Calcium; Cell Line; Dinoprostone; Epidermal Growth Factor; ErbB Receptors; Humans; Osteosarcoma; Phorbol Esters; Phorbols; Prostaglandins E; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1982 |
Interferon production by human marrow stromal cells.
Topics: Bone Marrow; Cell Line; Cells, Cultured; Fibroblasts; Humans; Interferon Type I; Osteosarcoma; Parainfluenza Virus 1, Human; Tetradecanoylphorbol Acetate; Time Factors | 1983 |
Stable differences in the adhesive properties of clonal variants derived from a human osteosarcoma.
Topics: Animals; Cell Adhesion; Cell Line; Clone Cells; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Osteosarcoma; Tetradecanoylphorbol Acetate | 1984 |
Relationship between mezerein-mediated biological responses and phorbol ester receptor occupancy.
Topics: Binding, Competitive; Caenorhabditis elegans Proteins; Carrier Proteins; Dinoprostone; Diterpenes; Epidermal Growth Factor; Humans; Kinetics; Osteosarcoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Prostaglandins E; Protein Kinase C; Receptors, Drug; Terpenes; Tetradecanoylphorbol Acetate | 1983 |
Parathyroid hormone and parathyroid hormone-related peptide activate the Na+/H+ exchanger NHE-1 isoform in osteoblastic cells (UMR-106) via a cAMP-dependent pathway.
Topics: Animals; Bone Neoplasms; Cell Line; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Enzyme Inhibitors; Humans; Isoquinolines; Kinetics; Osteosarcoma; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Protein Kinase C; Proteins; Rats; Recombinant Proteins; Second Messenger Systems; Sodium-Hydrogen Exchangers; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1995 |
Regulation of the TNF-alpha receptor in human osteosarcoma cells: role of microtubules and of protein kinase C.
Topics: Alkaloids; Cell Membrane; Cycloheximide; Ethers, Cyclic; Humans; Kinetics; Microtubules; Naphthalenes; Okadaic Acid; Osteosarcoma; Phosphoprotein Phosphatases; Polycyclic Compounds; Protein Kinase C; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vinblastine | 1993 |
EGF-mediated phosphorylation of extracellular signal-regulated kinases in osteoblastic cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Epidermal Growth Factor; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Osteoblasts; Osteosarcoma; Phosphorylation; Protein Kinase C; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Prostaglandin E2/parathyroid hormone-induced suppression of alkaline phosphatase activity is mediated by protein kinase C.
Topics: Alkaline Phosphatase; Alkaloids; Animals; Bucladesine; Calcimycin; Cyclic AMP; Cycloheximide; Dinoprostone; Isoquinolines; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinase C; Rats; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Rapid desensitization of parathyroid hormone dependent adenylate cyclase in perifused human osteosarcoma cells (SaOS-2).
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Cyclic AMP; Humans; Osteosarcoma; Parathyroid Hormone; Perfusion; Receptors, Parathyroid Hormone; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Production and release of matrix vesicles in the cell processes of TPA-treated human osteoblast-like cells.
Topics: Actins; Calcification, Physiologic; Calcium; Cytoplasm; Endoplasmic Reticulum; Humans; Microscopy, Electron, Scanning Transmission; Microscopy, Fluorescence; Organelles; Osteoblasts; Osteosarcoma; Tetracycline; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Role of calcium/protein kinase C in the regulation of DNA synthesis by parathyroid hormone-related peptide in osteoblastic osteosarcoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Cyclic AMP; DNA; Enzyme Activation; Humans; Isoquinolines; Osteoblasts; Osteosarcoma; Parathyroid Hormone-Related Protein; Piperazines; Protein Kinase C; Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Protein kinase C is crucial for the stimulation of sodium-dependent phosphate transport by parathyroid hormone-related peptide in osteoblast-like cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Animals; Biological Transport; Bone Neoplasms; Calcimycin; Calcium; Cell Line; Colforsin; Cytosol; Humans; Isoquinolines; Kinetics; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Phosphates; Piperazines; Protein Kinase C; Proteins; Rats; Sodium; Tetradecanoylphorbol Acetate | 1994 |
A novel phospholipase C inhibitor and phorbol esters reveal selective regulation of thrombin- and parathyroid hormone-stimulated signaling pathways in rat osteosarcoma cells.
Topics: Amino Acid Sequence; Animals; Bone Neoplasms; Calcium; Enzyme Activation; Estrenes; Inositol Phosphates; Molecular Sequence Data; Osteosarcoma; Parathyroid Hormone; Phorbol Esters; Protein Kinase C; Pyrrolidinones; Rats; Signal Transduction; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thrombin; Tumor Cells, Cultured; Type C Phospholipases | 1994 |
Endogenous protein kinase-C activation in osteoblast-like cells modulates responsiveness to estrogen and estrogen receptor levels.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaline Phosphatase; Alkaloids; Animals; Blotting, Northern; Calcium; Cell Division; Enzyme Activation; Estradiol; Homeostasis; Isoquinolines; Kinetics; Osteoblasts; Osteosarcoma; Piperazines; Protein Kinase C; Receptors, Estrogen; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1993 |
Modulation of parathyroid hormone-sensitive adenylate cyclase in ROS 17/2.8 cells by dexamethasone 1,25-dihydroxyvitamin D3 and protein kinase C.
Topics: Adenylyl Cyclases; Animals; Calcitriol; Colforsin; Dexamethasone; Enzyme Activation; Kinetics; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Cross talk of dual-signal transduction systems in the regulation of DNA synthesis by parathyroid hormone in osteoblastic osteosarcoma cells.
Topics: Bucladesine; Calcimycin; Cyclic AMP; DNA; Dose-Response Relationship, Drug; Ionomycin; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Involvement of dual signal transduction systems in the stimulation of osteoclast-like cell formation by parathyroid hormone and parathyroid hormone-related peptide.
Topics: Animals; Bucladesine; Calcimycin; Cells, Cultured; Culture Media, Conditioned; Culture Media, Serum-Free; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Ionomycin; Mice; Mice, Inbred Strains; Osteoblasts; Osteoclasts; Osteosarcoma; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Peptide Fragments; Protein Kinase C; Protein Kinases; Proteins; Rats; Second Messenger Systems; Signal Transduction; Teriparatide; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Effect of modulation of protein kinase C activity on cisplatin cytotoxicity in cisplatin-resistant and cisplatin-sensitive human osteosarcoma cells.
Topics: Cisplatin; Drug Interactions; Drug Resistance; Humans; Osteosarcoma; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Translocation of retinoblastoma protein associated with tumor cell growth inhibition.
Topics: Blotting, Western; Cell Differentiation; Cell Division; Cell Nucleolus; DNA Replication; DNA, Neoplasm; Humans; Immunoenzyme Techniques; Immunohistochemistry; Leukemia, Monocytic, Acute; Molecular Weight; Osteosarcoma; Retinoblastoma Protein; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Regulation of NGF, BDNF and LNGFR gene expression in ROS 17/2.8 cells.
Topics: Animals; Brain-Derived Neurotrophic Factor; Calcitriol; Gene Expression Regulation; Nerve Growth Factors; Nerve Tissue Proteins; Osteosarcoma; Rats; Receptors, Nerve Growth Factor; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
24,25(OH)2 vitamin D3 modulates the L-type Ca2+ channel current in UMR 106 cells: involvement of protein kinase A and protein kinase C.
Topics: 24,25-Dihydroxyvitamin D 3; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Channels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electric Conductivity; Enzyme Inhibitors; Naphthalenes; Osteoblasts; Osteosarcoma; Patch-Clamp Techniques; Protein Kinase C; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Homologous regulation of the rat C1a calcitonin receptor (CTR) in nonosteoclastic cells is independent of CTR messenger ribonucleic acid changes and cyclic adenosine 3',5'-monophosphate-dependent protein kinase activation.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Calcitonin; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Humans; Kidney; Kinetics; Osteosarcoma; Polymerase Chain Reaction; Promoter Regions, Genetic; Rats; Receptors, Calcitonin; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1996 |
Role of protein kinase C alpha, Arf, and cytoplasmic calcium transients in phospholipase D activation by sodium fluoride in osteoblast-like cells.
Topics: ADP-Ribosylation Factors; Biological Transport; Calcium; Cell Line; Cytoplasm; Drug Synergism; Enzyme Activation; GTP-Binding Proteins; Humans; Isoenzymes; Osteoblasts; Osteosarcoma; Phospholipase D; Protein Kinase C; Protein Kinase C-alpha; Sodium Fluoride; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Expression of p27Kip1 in osteoblast-like cells during differentiation with parathyroid hormone.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbazoles; Cell Cycle Proteins; Cell Differentiation; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Enzyme Inhibitors; G1 Phase; Gene Expression; Indoles; Microtubule-Associated Proteins; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Pyrroles; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1997 |
Parathyroid hormone versus phorbol ester stimulation of activator protein-1 gene family members in rat osteosarcoma cells.
Topics: Animals; Blotting, Northern; Bone Neoplasms; Carcinogens; Chloramphenicol O-Acetyltransferase; Collagenases; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Genes, Reporter; Osteoblasts; Osteosarcoma; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Rats; RNA, Messenger; Teriparatide; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1997 |
Biglycan gene promoter activity in osteosarcoma cells is regulated by cyclic AMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Biglycan; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Extracellular Matrix Proteins; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Indoles; Osteosarcoma; Plasmids; Promoter Regions, Genetic; Proteoglycans; Pyrroles; RNA, Messenger; Sequence Deletion; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1997 |
Parathyroid hormone (1-34)-mediated interleukin-6 induction.
Topics: Becaplermin; Calcimycin; Colforsin; Dinoprostone; Drug Interactions; Gene Expression; Humans; Interleukin-1; Interleukin-6; Osteosarcoma; Plasmids; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Proto-Oncogene Proteins c-sis; Recombinant Fusion Proteins; Teriparatide; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1997 |
Phorbol 12-myristate 13-acetate and 1,25-dihydroxyvitamin D3 regulate 1,25-dihydroxyvitamin D3 receptors synergistically in rat osteosarcoma cells.
Topics: Animals; Calcitriol; Drug Synergism; Osteosarcoma; Rats; Receptors, Calcitriol; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Parathyroid hormone up-regulation of connexin 43 gene expression in osteoblasts depends on cell phenotype.
Topics: 3T3 Cells; Animals; Calcitriol; Carcinogens; Connexin 43; Estrogens; Gene Expression; Gene Expression Regulation; Genes; Mice; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Phenotype; Proteins; Rats; RNA; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
Regulation of prostaglandin G/H synthase-2 expression by interleukin-1 in human osteoblast-like cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Transformed; Colforsin; Cycloheximide; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Interleukin-1; Isoenzymes; Membrane Proteins; Osteoblasts; Osteosarcoma; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Synthesis Inhibitors; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1998 |
Transcription of alpha2 integrin gene in osteosarcoma cells is enhanced by tumor promoters.
Topics: Antigens, CD; Blotting, Northern; Carcinogens; Cell Adhesion; Collagen; Collagenases; Flow Cytometry; Humans; Integrin alpha2; Integrin alpha3; Integrin alpha5; Integrin alphaV; Integrin beta1; Integrins; Matrix Metalloproteinase 1; Okadaic Acid; Osteosarcoma; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation | 1998 |
Two human osteoblast-like osteosarcoma cell lines show distinct expression and differential regulation of parathyroid hormone-related protein.
Topics: Colforsin; Exons; Humans; Neoplasm Proteins; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Direct measurement of hormone-induced acidification in intact bone.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Animals, Newborn; Bone and Bones; Bone Neoplasms; Bucladesine; Calcium Signaling; Carbonic Anhydrases; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Extracellular Space; Humans; Hydrogen-Ion Concentration; Mice; Organ Culture Techniques; Organ Specificity; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinase C; Second Messenger Systems; Skull; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 2000 |
Molecular analysis of the hematopoiesis supporting osteoblastic cell line U2-OS.
Topics: Activated-Leukocyte Cell Adhesion Molecule; Antigens, CD; Antigens, CD34; Antigens, Differentiation, T-Lymphocyte; Cell Adhesion Molecules; Cell Division; Cell Membrane; Cells, Cultured; Coculture Techniques; Cytokines; Flow Cytometry; Gene Library; Growth Substances; Hematopoiesis; Hematopoietic Stem Cells; Humans; Hyaluronan Receptors; Integrins; Ionomycin; Osteoblasts; Osteosarcoma; Receptors, Cell Surface; Receptors, Chemokine; Receptors, CXCR3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate | 2000 |
Intra- and intercellular Ca(2+)-transient propagation in normal and high glucose solutions in ROS cells during mechanical stimulation.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Communication; Cell Line; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Fluorescent Dyes; Gadolinium; Gap Junctions; Glucose; Heptanol; Microscopy, Confocal; Osteosarcoma; Protein Kinase C; Rats; Stress, Mechanical; Tetradecanoylphorbol Acetate; Thapsigargin; Verapamil | 2001 |
Neurotransmitter action in osteoblasts: expression of a functional system for serotonin receptor activation and reuptake.
Topics: Animals; Carcinogens; Carrier Proteins; Down-Regulation; Gene Expression; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT1D; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; RNA, Messenger; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured | 2001 |
Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties.
Topics: Antigens, Neoplasm; Apoptosis; Base Sequence; Carcinoma; Cell Differentiation; Cell Division; Chromosomes, Human, Pair 1; Cloning, Molecular; Dimethyl Sulfoxide; Diterpenes; Female; Gene Expression Regulation, Neoplastic; Genes; Genes, Tumor Suppressor; Glioblastoma; Growth Substances; HL-60 Cells; Humans; Interferon Type I; Interleukins; K562 Cells; Male; Melanocytes; Melanoma; Molecular Sequence Data; Molecular Weight; Neoplasm Proteins; Neoplasms; Organ Specificity; Osteosarcoma; Recombinant Fusion Proteins; Recombinant Proteins; RNA, Messenger; RNA, Neoplasm; Terpenes; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 2001 |
1,25-Dihydroxyvitamin D3 selectively translocates PKCalpha to nuclei in ROS 17/2.8 cells.
Topics: Blotting, Northern; Bone Neoplasms; Calcitriol; Calcium Channel Agonists; Cell Nucleus; Dactinomycin; Fluorescent Antibody Technique; Gene Expression; Humans; Immunoblotting; Isoenzymes; Osteocalcin; Osteosarcoma; Protein Kinase C; Protein Kinase C-alpha; RNA, Messenger; Subcellular Fractions; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 2002 |
The direct involvement of cAMP-dependent protein kinase in the regulation of collagen synthesis by parathyroid hormone (PTH) and PTH-related peptide in osteoblast-like osteosarcoma cells (UMR-106).
Topics: Animals; Bucladesine; Calcimycin; Cell Line; Collagen; Cyclic AMP; Ionomycin; Kinetics; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Proline; Protein Kinases; Proteins; Rats; Tetradecanoylphorbol Acetate; Thionucleotides; Tritium | 1992 |
Dissociation between parathyroid hormone-stimulated cAMP and calcium increase in UMR-106-01 cells.
Topics: Calcium; Cyclic AMP; Dinoprost; Humans; Osteosarcoma; Parathyroid Hormone; Peptide Fragments; Receptors, Cell Surface; Receptors, Parathyroid Hormone; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
The effects of prostaglandin E2, parathyroid hormone, and epidermal growth factor on mitogenesis, signaling, and primary response genes in UMR 106-01 osteoblast-like cells.
Topics: Animals; Bone Neoplasms; Calcium; Colforsin; Cyclic AMP; Cycloheximide; Dinoprostone; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Immediate-Early Proteins; Inositol Phosphates; Mitosis; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinases; Radioimmunoassay; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thymidine; Transcription Factors; Tritium; Tumor Cells, Cultured; Zinc Fingers | 1992 |
Protein kinase C modulates parathyroid hormone- but not prostaglandin E2-mediated stimulation of cyclic AMP production via the inhibitory guanine nucleotide binding protein in UMR-106 osteosarcoma cells.
Topics: Adenylate Cyclase Toxin; Animals; Cyclic AMP; Dinoprostone; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Osteosarcoma; Parathyroid Hormone; Pertussis Toxin; Phosphorylation; Precipitin Tests; Protein Kinase C; Radioimmunoassay; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
Transformation of non-tumorigenic osteoblast-like human osteosarcoma cells by hexavalent chromates: alteration of morphology, induction of anchorage-independence and proteolytic function.
Topics: Animals; Carcinogens; Cell Adhesion; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Chromates; Electrochemistry; Humans; Hydrolysis; Male; Methylcholanthrene; Mice; Mice, Nude; Neoplasms, Experimental; Osteoblasts; Osteosarcoma; Plasminogen Activators; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 1992 |
A phorbol ester induces secretion of alkaline phosphatase activity in human osteosarcoma cells.
Topics: Alkaline Phosphatase; Calcium; Cell Division; DNA; Dose-Response Relationship, Drug; Humans; Microscopy, Electron; Osteoblasts; Osteosarcoma; Phosphorus; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Ultracentrifugation | 1992 |
Protein kinase C is involved in PTH-induced homologous desensitization by directly affecting PTH receptor in the osteoblastic osteosarcoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cyclic AMP; GTP-Binding Proteins; Isoquinolines; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Receptors, Cell Surface; Receptors, Parathyroid Hormone; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Prostaglandin-induced changes in calcium uptake and cAMP production in osteoblast-like cells: role of protein kinase C.
Topics: Calcium; Cell Line; Cyclic AMP; Dinoprostone; Humans; Osteoblasts; Osteosarcoma; Phorbol Esters; Protein Kinase C; Radioimmunoassay; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Protein kinase C activating phorbolesters enhance the cyclic AMP response to parathyroid hormone, forskolin and choleratoxin in mouse calvarial bones and rat osteosarcoma cells.
Topics: Adenylyl Cyclases; Animals; Bone and Bones; Cattle; Cholera Toxin; Colforsin; Culture Techniques; Cyclic AMP; Enzyme Activation; Mice; Osteosarcoma; Parathyroid Hormone; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Regulation of Na-K-2Cl cotransport in osteoblasts.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carrier Proteins; Cell Line; Chlorides; Colforsin; Cyclic AMP; Dinoprostone; Egtazic Acid; Kinetics; Osteoblasts; Osteosarcoma; Ouabain; Parathyroid Hormone; Potassium; Rubidium; Second Messenger Systems; Sodium; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate | 1991 |
Structure-function relationship of parathyroid hormone: activation of phospholipase-C, protein kinase-A and -C in osteosarcoma cells.
Topics: Animals; Calcium; Enzyme Activation; Inositol Phosphates; Osteosarcoma; Parathyroid Hormone; Peptide Fragments; Protein Kinase C; Protein Kinases; Rats; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases | 1992 |
The protein kinase-C activation domain of the parathyroid hormone.
Topics: Animals; Enzyme Activation; Osteosarcoma; Parathyroid Hormone; Peptide Fragments; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases | 1992 |
Differential regulation of the 55 and 44 kDa forms of secreted phosphoprotein 1 (SPP-1, osteopontin) in normal and transformed rat bone cells by osteotropic hormones, growth factors and a tumor promoter.
Topics: Animals; Calcitriol; Cell Line; Cell Line, Transformed; Cells, Cultured; Concanavalin A; Epidermal Growth Factor; Growth Substances; Nucleic Acid Hybridization; Osteopontin; Osteosarcoma; Parathyroid Hormone; Platelet-Derived Growth Factor; Precipitin Tests; RNA, Messenger; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transforming Growth Factor beta; Tretinoin | 1991 |
Thrombin and parathyroid hormone mobilize intracellular calcium in rat osteosarcoma cells by distinct pathways.
Topics: Animals; Bradykinin; Calcium; Cell Line; Dose-Response Relationship, Drug; Inositol Phosphates; Kinetics; Osteosarcoma; Parathyroid Hormone; Peptide Fragments; Rats; Teriparatide; Tetradecanoylphorbol Acetate; Thrombin; Time Factors | 1991 |
Parathyroid hormone (PTH)-induced intracellular Ca2+ signalling in naive and PTH-desensitized osteoblast-like cells (ROS 17/2.8): pharmacological characterization and evidence for synchronous oscillation of intracellular Ca2+.
Topics: Animals; Calcium; Calcium Channel Blockers; Cholera Toxin; Drug Tolerance; Neomycin; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Periodicity; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1991 |
Interactive regulation of signalling pathways in bone cells: possible modulation of PGE2-stimulated adenylyl cyclase activity by protein kinase C.
Topics: Adenylyl Cyclases; Animals; Cattle; Dinoprostone; Osteosarcoma; Protein Kinase C; Rats; Salmon; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1990 |
Effects of phorbol esters and pertussis toxin on agonist-stimulated cyclic AMP production in rat osteosarcoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Cyclic AMP; Drug Synergism; Interphase; Osteosarcoma; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella | 1986 |
Protein kinase C-activated calcium channel in the osteoblast-like clonal osteosarcoma cell line UMR-106.
Topics: Calcium; Calcium Channel Blockers; Cell Line; Colforsin; Ion Channels; Kinetics; Osteoblasts; Osteosarcoma; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate | 1987 |
Regulation of osteosarcoma EGF receptor affinity by phorbol ester and cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Colforsin; Cyclic AMP; Epidermal Growth Factor; ErbB Receptors; Humans; Iodine Radioisotopes; Osteosarcoma; Parathyroid Hormone; Tetradecanoylphorbol Acetate | 1989 |
A novel integrin beta subunit is associated with the vitronectin receptor alpha subunit (alpha v) in a human osteosarcoma cell line and is a substrate for protein kinase C.
Topics: Electrophoresis, Polyacrylamide Gel; Fibroblasts; Humans; Integrins; Osteosarcoma; Peptide Mapping; Phosphorylation; Precipitin Tests; Protein Kinase C; Receptors, Immunologic; Receptors, Vitronectin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Calcium and protein kinase C enhance parathyroid hormone- and forskolin-stimulated adenylate cyclase in ROS 17/2.8 cells.
Topics: Adenylyl Cyclases; Animals; Calcium; Cell Line; Colforsin; Osteosarcoma; Parathyroid Hormone; Protein Kinase C; Rats; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Parathyroid hormone causes translocation of protein kinase-C from cytosol to membranes in rat osteosarcoma cells.
Topics: Animals; Biological Transport; Calcium; Cell Membrane; Cyclic AMP; Cytosol; Diglycerides; Enzyme Activation; Kinetics; Molecular Weight; Osteosarcoma; Parathyroid Hormone; Phosphatidylserines; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Second messenger signaling in the regulation of collagenase production by osteogenic sarcoma cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Line; Ethers; Immunoenzyme Techniques; Ionomycin; Kinetics; Microbial Collagenase; Osteosarcoma; Parathyroid Hormone; Rats; Recombinant Proteins; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1989 |
Production of parathyroid hormone-like peptide in a human osteosarcoma cell line: stimulation by phorbol esters and epidermal growth factor.
Topics: Adenylyl Cyclases; Cell Line; Epidermal Growth Factor; Humans; Neoplasm Proteins; Osteosarcoma; Parathyroid Hormone; Parathyroid Hormone-Related Protein; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Interleukin-6 is produced by bone and modulated by parathyroid hormone.
Topics: Animals; Antibodies, Monoclonal; Bone and Bones; Calcitonin; Cell Division; Cells, Cultured; Dexamethasone; Humans; Hybridomas; Interleukin-1; Interleukin-6; Kinetics; Mice; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Possible involvement of protein kinase C in parathyroid hormone degradation by osteoblast-like rat osteosarcoma cell line UMR106.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Diglycerides; Isoquinolines; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Piperazines; Protein Kinase C; Rats; Sarcoma, Experimental; Sulfonamides; Tetradecanoylphorbol Acetate | 1987 |
Time-dependent changes in protein kinase C distribution and disappearance in phorbol ester-treated human osteosarcoma cells.
Topics: Cell Line; Dinoprostone; Enzyme Activation; Humans; Osteosarcoma; Prostaglandins E; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Tissue Distribution | 1987 |
Evidence for increased synthesis as well as increased degradation of protein kinase C after treatment of human osteosarcoma cells with phorbol ester.
Topics: Bone Neoplasms; Cell Line; Humans; Molecular Weight; Osteosarcoma; Protein Kinase C; Subcellular Fractions; Tetradecanoylphorbol Acetate; Time Factors | 1987 |
Differing patterns of cytotoxicity of the phorbol ester 12-O-tetradecanoylphorbol 13-acetate in various human cell strains.
Topics: Breast Neoplasms; Cell Line; Cell Survival; Female; Fibroblasts; Humans; Kinetics; Male; Melanoma; Osteosarcoma; Phorbols; Prostatic Neoplasms; Tetradecanoylphorbol Acetate | 1985 |