tetradecanoylphorbol acetate has been researched along with Neoplasms in 193 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 72 (37.31) | 18.7374 |
| 1990's | 38 (19.69) | 18.2507 |
| 2000's | 62 (32.12) | 29.6817 |
| 2010's | 19 (9.84) | 24.3611 |
| 2020's | 2 (1.04) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Irie, K; Kamachi, H; Murakami, A; Nagai, H; Nakagawa, Y; Tanaka, K; Tokuda, H; Yanagita, RC | 1 |
| Barraja, P; Carbone, A; Cascioferro, S; Cilibrasi, V; Cirrincione, G; Diana, P; Doria, F; Frasson, I; Freccero, M; Giallombardo, D; Montalbano, A; Parrino, B; Richter, SN; Salvador, A; Spanò, V | 1 |
| Cao, X; Guo, Y; Zhang, S | 1 |
| Cho, Y; Jeon, SD; Kim, C; Kim, KY; Kim, MG; Lee, HS; Yoon, J; Yoon, MJ | 1 |
| Avivi, A; Band, M; Hirsh, M; Iancu, TC; Malik, A; Manov, I; Shams, I; Sotnichenko, N | 1 |
| Bouvard, C; Bussolino, F; Chiaverina, G; di Blasio, L; Gagliardi, PA; Helley, D; Jain, RK; Primo, L; Puliafito, A; Seano, G; Serini, G; Sessa, R; Sorokin, L; Tarone, G | 1 |
| Cervini-Silva, J; Gómez-Vidales, V; Montoya, A; Nieto-Camacho, A; Palacios, E; Ramírez-Apan, MT; Ronquillo de Jesús, E | 1 |
| Brown, WL; Burns, MB; Harris, RS; Kosyakovsky, L; Leonard, B; Luengas, EM; McCann, JL; McDougle, RM; Molan, AM; Parker, PJ; Starrett, GJ | 1 |
| Hiraishi, H; Horii, Y; Makiyama, T; Sai, XB; Sakane, H; Shirataki, H | 1 |
| Ichiishi, E; Kobayashi, Y; Lee, KH; Miyake, K; Morita, C; Nakagawa-Goto, K; Saito, Y; Suzuki, N; Tokuda, H | 1 |
| Cora, EM; Maihle, NJ; Negron-Vega, L; Nieves-Alicea, R; Perez-Torres, M; Valle, BL | 1 |
| Chen, YW; Fodstad, O; Tekle, C | 1 |
| Jackson, JA; Klykov, AA; Mikirova, NA; Riordan, NH | 1 |
| Hua, H; Jiang, Z; Li, Y; Liu, Y; Wang, Y; Wang, Z; Zhang, J; Zhu, B | 1 |
| Anto, RJ; Bava, SV; Cheriyan, VT; Laladhas, KP; Puliappadamba, VT; Unnithan, RG; Vijayammal, PL | 1 |
| Fujiki, H; Suganuma, M | 1 |
| Kalinovsky, T; Monterrey, JC; Niedzwiecki, A; Rath, M; Roomi, MW | 2 |
| Bode, AM; Cho, YY; Dong, Z; Malakhova, ML; Pugliese, A; Yao, K | 1 |
| Boyle, GM; Cozzi, SJ; Mason, SA; Parsons, PG; Pavey, SJ; Pierce, CJ | 1 |
| Kofler, R; Ploner, C; Villunger, A | 1 |
| Amici, M; Angeletti, M; Bonfili, L; Cecarini, V; Cuccioloni, M; Eleuteri, AM; Fioretti, E; Giuliani, L; Grimaldi, S | 1 |
| Bartges, JW; Jones, MM; Kania, SA; LeBlanc, AK; LeBlanc, CJ | 1 |
| Miyamoto, S; Nakashima, M; Sonoda, K; Wake, N | 1 |
| Hamashima, Y; Hasegawa, J; Kajimoto, T; Node, M; Tanaka, R; Tokuda, H; Tsujii, H; Yamada, T | 1 |
| Kim, JY; Lee, TJ; Noh, HJ; Song, IH; Sung, EG | 1 |
| Bae, HS; Han, SI; Jeon, HM; Ju, MK; Kang, HS; Kim, CH; Lee, SY; Lim, SC; Park, HG | 1 |
| Braess, J; Holdenrieder, S; Kolligs, FT; Manukyan, D; Stieber, P | 1 |
| Calabriso, N; Carluccio, MA; De Caterina, R; Martines, G; Massaro, M; Pellegrino, M; Scoditti, E; Storelli, C | 1 |
| Lazo, PA; Vázquez-Cedeira, M | 1 |
| Mabjeesh, N; Simons, J; Willard, M; Zhong, H | 1 |
| Amara, FM; Burton, TR; Kashour, T; Wright, JA | 1 |
| Levine, L | 2 |
| Demine, R; Sherev, T; Walden, P | 1 |
| Bowden, GT; Chen, QM; Dilley, TK | 1 |
| Dosescu, J; Moin, K; Sameni, M; Sloane, BF | 1 |
| Miyoshi, N; Nakamura, Y; Osawa, T; Takabayashi, S | 1 |
| Dinh, DH; Gujrati, M; Gumidyala, KV; Mohanam, S; Olivero, WC; Rao, JS; Waldron, KG; Yanamandra, N | 1 |
| Akihisa, T; Iizuka, M; Metori, K; Nishino, H; Ogata, M; Shimizu, N; Suzuki, T; Tokuda, H; Ukiya, M | 1 |
| Gho, YS; Hahm, ER; Kim, KW; Park, C; Park, S; Yang, CH | 1 |
| Chignell, CF; He, YY; Huang, JL | 1 |
| Anglard, P; Auberger, P; Collazos, A; Defamie, V; Fromigué, O; Guérineau, N; Joubert, D; Louis, K; Mari, B; Shipp, MA | 1 |
| Chun, YS; Lee, ES; Lee, JW; Lim, JH; Park, JW; You, HJ | 1 |
| Blasco, MA; Cayuela, ML; Flores, JM | 1 |
| Brando, C; Campbell, KS; Catina, TL; Kovacs, E; Medina, R; Mukhopadhyay, S; Patel, P; Santoli, D | 1 |
| Furuya, T; Inomata, K; Kawauchi, S; Oga, A; Sasaki, K | 1 |
| Aisner, J; Chang, R; Conney, A; Cui, XX; Dudek, L; Goodell, L; Grospe, S; Han, ZT; Lin, Y; Manago, J; Martin, J; Riley, J; Rubin, EH; Schaar, D; Strair, RK | 1 |
| Baj-Krzyworzeka, M; Baran, J; Brański, P; Ratajczak, MZ; Szatanek, R; Urbanowicz, B; Weglarczyk, K; Zembala, M | 1 |
| Chen, RS; Huang, JY; Hung, SK; Lai, YW; Lee, YT; Li, C; Liu, ST; Shieh, B; Tang, YC; Teng, RH; Tung, CP; Wei, TT; Yen, CY | 1 |
| Chow, S; Hedley, D; Tong, FK | 1 |
| Bagley, R; Boutin, P; Brondyk, W; Burrier, R; Byrne, A; Dufault, MR; Klinger, K; Liu, D; Madden, S; Nacht, M; Puorro-Radzwill, K; Reczek, D; Roberts, B; Rouleau, C; Roy, A; Rulli, L; Shankara, S; St Martin, T; Teicher, BA; Weber, W; Zhang, M | 1 |
| Ikeda, Y; Murakami, A; Nishizawa, T; Ohigashi, H | 1 |
| Byun, HS; Hur, GM; Junn, E; Kim, JM; Park, J; Park, KA; Piao, L; Seok, JH; Shin, S; Won, M; Yang, KJ; Yoon, WH | 1 |
| Chiou, YH; Chu, CY; Kao, ES; Lee, YJ; Lin, WL; Tseng, TH | 1 |
| Aggarwal, BB; Ichikawa, H; Kumar, MA; Nair, MS; Oommen, OV; Sheeja, DB; Takada, Y | 1 |
| Huang, Q; Li, Z; Ong, CN; Shen, HM; Wu, X; Zhang, S | 1 |
| Diwan, BA; Liu, J; Waalkes, MP | 1 |
| Bai, J; Chen, H; Chen, R; Li, A; Liu, Z; Mao, W; Ye, J; Zhou, J | 1 |
| Bai, J; Baybutt, R; Lu, J; Sylvester, J; Wang, J; Wang, W; Xie, L | 1 |
| Bode, AM; Cho, YY; Dong, Z; Heo, YS; Kang, NJ; Lee, HJ; Lee, KW; Rogozin, EA | 1 |
| Jeong, YJ; Kim, CH; Kim, M; Lee, IS; Lee, SO | 1 |
| Kloog, Y; Levy, R; Makovski, V; Raz, A; Shalom-Feuerstein, R | 1 |
| Adiseshaiah, P; Kalvakolanu, DV; Li, J; Reddy, SP; Vaz, M | 1 |
| Beltran, L; Carbajal, S; Digiovanni, J; Hursting, SD; Leroith, D; Moore, T; Perkins, SN; Yakar, S | 1 |
| Chinkers, M; Garbers, DL | 1 |
| Adolf, W; Hecker, E; Hergenhahn, M; Schmidt, R; Sorg, B | 1 |
| Arcoleo, J; Backer, J; Gattoni-Celli, S; Hsiao, WL; Jeffrey, A; Kirschmeier, P; Okin, E; Weinstein, IB | 1 |
| Estensen, RD | 1 |
| Gillespie, E; Lichtenstein, LM; Schleimer, RP | 1 |
| Aguet, M; Keller, R; Stitz, L; Tovey, M | 1 |
| Antecol, MH; Mukherjee, BB | 1 |
| Amoruso, M; Goldstein, BD; Stone, DS; Troll, W; Witz, G | 1 |
| Edwards, I; Kucera, LS; Respess, RA; Waite, M | 1 |
| Broder, S; DiNapoli, AM; Pincus, SH; Schooley, WR | 1 |
| De Larco, JE; Shoyab, M; Todaro, GJ | 1 |
| Bockman, RS; Honn, KV; Marnett, LJ | 1 |
| Nathan, CF | 1 |
| Destrempes, M; Latt, SA; Stossel, TP; Weitberg, AB; Weitzman, SA | 1 |
| Perera, FP | 1 |
| Kensler, TW; Trush, MA | 1 |
| Klein-Szanto, AJ; Marchok, AC; Pal, BC; Terzaghi, M | 1 |
| Borek, C; Cleaver, JE; Fujiki, H | 1 |
| Frenkel, K; Teebor, G; Troll, W | 1 |
| Astrup, EG; Iversen, OH | 1 |
| Goerttler, K; Hesse, B; Loehrke, H; Schweizer, J | 1 |
| De Luca, LM | 2 |
| Enomoto, T; Martel, N; Yamasaki, H | 1 |
| Galsky, AG; Lipetz, PD; Stephens, RE | 1 |
| Kopelovich, L | 2 |
| Sugimura, T | 2 |
| Hamilton, JA; Moore, MA; Sensenbrenner, LL; Stuart, RK | 1 |
| Boutwell, RK; O'Leary, P; Perrella, FW | 1 |
| Adolf, W; Hecker, E; Keist, R; Keller, R; Opferkuch, HJ; Schmidt, R | 1 |
| Grzelakowska-Sztabert, B | 1 |
| Symthies, JR | 1 |
| Bonardelle, D; Goutner, A; Nasrat, F; Rameau, G | 1 |
| Varshavsky, A | 1 |
| Chao, WR; Dawson, MI; Fung, VA; Helmes, CT; Hobbs, PD; Kuhlmann, K | 1 |
| Lillehaug, JR | 1 |
| Kuroda, M; Mimaki, Y; Nishino, A; Nishino, H; Sashida, Y; Satomi, Y | 1 |
| Jou, I; Kim, NK; Lee, MS; Lee, SH; Lim, IK; Park, SC; Seo, JS | 1 |
| Guillaume, T; Hamdan, O; Leblanc, P; Rubinstein, DB; Sekhavat, M; Symann, ML | 1 |
| Chorváth, B; Duraj, J; Holománová, D; Hunáková, L; Sedlák, J | 1 |
| Larrick, JW; Wright, SC; Zhong, J | 1 |
| Broxterman, HJ; Eekman, CA; Kuiper, CM; Lankelma, J; Pinedo, HM; Schuurhuis, GJ; Versantvoort, CH | 1 |
| Böhme, B; Bräuninger, A; Holtrich, U; Karn, T; Rübsamen-Waigmann, H; Strebhardt, K; Wolf, G | 1 |
| Beninati, S; Bergamini, A; Coppola, S; Ghibelli, L; Nosseri, C | 1 |
| Goh, SH; Hew, NF; Norhanom, AW; Yadav, M | 1 |
| Boone, CW; Kelloff, GJ; Steele, VE | 1 |
| Coles, M; Varvayanis, S; Yen, A | 1 |
| Satomi, Y | 1 |
| Barrett, JC | 2 |
| Harris, AL; Philip, PA | 1 |
| Eggett, T; Holguin, MH; Martin, CB; Parker, CJ | 1 |
| Carroll, SM; Kamps, MP; White, FC | 1 |
| Honn, KV; Tang, DG | 1 |
| Damtew, B; Spagnuolo, PJ | 1 |
| Andersson, AC; Botling, J; Cohen, M; Fan, W; Larsson, E; Nilsson, K; Oberg, F; Rigby, S; Venables, P | 1 |
| Belury, MA; Liu, KL | 1 |
| Martin, KJ; Sager, R; Sheng, S; Zhang, M | 1 |
| Chang, RL; Conney, AH; Cui, YL; Han, ZT; He, LM; Newmark, HL; Sun, JZ; Tong, YK; Wang, TY; Zhang, H; Zhang, Y | 1 |
| Ahlers, C; Kreideweiss, S; Nordheim, A; Rühlmann, A | 1 |
| Chun, KS; Kim, HS; Kim, OH; Lee, JM; Lee, SS; Moon, A; Park, KK; Sohn, Y; Surh, YJ | 1 |
| Clothier, RH; Johnson, RO; McMahan, R; Ruben, LN | 1 |
| Englert, C; Günes, C; Lichtsteiner, S; Vasserot, AP | 1 |
| Bureau, JP; Carillo, S; Guiraud, I; Henry, L; Lavabre-Bertrand, T | 1 |
| Iwamoto, M; Matsunaga, S; Minami, T; Nishino, H; Ohtsu, H; Tanaka, R; Tokuda, H; Yoshitake, A | 1 |
| Azuine, MA; Kapadia, GJ; Konoshima, T; Nishino, H; Takasaki, M; Takayasu, J; Tokuda, H | 1 |
| Chun, KS; Han, SS; Keum, YS; Lee, SS; Seo, HJ; Surh, YJ | 1 |
| Koshiba, T; Koshimizu, K; Murakami, A; Nakamura, Y; Nishino, H; Ohigashi, H; Ohto, Y; Tokuda, H; Yano, M | 1 |
| Dannenberg, AJ; Hart, JC; Lin, DT; Subbaramaiah, K | 1 |
| Abbas, T; Barile, N; Chatakondu, K; Foster, DA; Hornia, A; Kaplan, P; Lu, Z; Zhong, M | 1 |
| Hurta, RA; Yeung, O | 1 |
| Barnes, S; Boersma, BJ; Darley-Usmar, VM; Kim, H; Kirk, M; Patel, R; Smith, M; Wang, CC; Xu, J | 1 |
| Amoscato, AA; Hunter, OC; Kalinski, P; Kanto, T; Lotze, MT | 1 |
| Akihisa, T; Ichiishi, E; Mukainaka, T; Nishino, H; Tokuda, H; Toriumi, M; Ukiya, M; Yasukawa, K | 1 |
| Konoshima, T; Kuroki, S; Nishino, H; Takasaki, M; Tokuda, H | 1 |
| Alexandre, D; Chada, S; Chen, Y; Christiansen, KA; Fisher, PB; Goldstein, NI; Gopalkrishnan, RV; Huang, EY; Huberman, E; Jiang, H; Kang, D; Lebedeva, IV; Leszczyniecka, M; Lin, JJ; Madireddi, MT; Mei, MX; Mhashilkar, AB; Pestka, S; Sivo, F; Su, Z; Vozhilla, N | 1 |
| Akihisa, T; Ichiishi, E; Kasahara, Y; Mukainaka, T; Nishino, H; Suzuki, H; Tokuda, H; Ukiya, M; Yasukawa, K | 1 |
| Ao, Y; Fukumoto, H; Kuroki, T; Mori, M; Naruse, I; Nishio, K; Ohmori, T; Saijo, N | 1 |
| Azuine, MA; Hang, E; Kapadia, GJ; Mukainaka, T; Nishino, H; Sridhar, R; Tokuda, H | 1 |
| Athar, M; Bhasin, G; Kauser, H | 1 |
| Scribner, JD; Süss, R | 1 |
| Marx, JL | 1 |
| Sivak, A | 1 |
| Huffman, JC; Wilson, SR | 1 |
| Ballin, M; Farina, AR; Hartzler, JL; Mackay, AR; Nason, AM; Pelina, MD; Thorgeirsson, UP | 1 |
| Endo, Y; Kida, Y; Mai, M; Sasaki, T; Sato, H; Seiki, M; Tanaka, J | 1 |
| Dallegri, F; Ottonello, L | 1 |
| Mesnil, M; Nakazawa, H; Yamasaki, H | 1 |
| Adams, AK; Hanausek, M; Mirowski, M; Sherman, U; Slaga, TJ; Walaszek, Z | 1 |
| Taniguchi, N | 1 |
| Bhargava, M; Donovan, MA; Goldberg, ID; Kacinski, BM; Liu, D; Reiss, M; Rosen, EM; Setter, E | 1 |
| Cabrera, T; Concha, A; Garrido, F; Gomez, O; Perez-Ayala, M; Redondo, M; Ruiz-Cabello, F | 1 |
| Braun, DP; Casey, LC; Harris, JE; Siziopikou, KP | 1 |
| Balmain, A; Parkinson, K | 1 |
| Marks, PA; Rifkind, RA | 1 |
| Ha, YL; Pariza, MW | 1 |
| Färber, B; Fusenig, N; Kinzel, V; Petrusevska, RT | 1 |
| Fisher, PB; Grant, S | 1 |
| Ikeda, I; Kikuchi, K; Kitagawa, Y; Nagao, M; Sugimura, T; Tahira, T; Tsuiki, S | 1 |
| Braun, DP; Harris, JE | 1 |
| Dancona, C; Dawood, FA; Moreira, SS; Shimizu, LT | 1 |
| Baughman, RP; Buchsbaum, J; Doers, J; Lower, EE | 1 |
| Ma, RD; Yu, LJ | 1 |
| Delhanty, JD; Rider, SH | 1 |
| Baten, A; Nabi, ZF; Zucker-Franklin, D | 1 |
| Bonvini, E; Ceccorulli, LM; Gallin, JI; Kleinerman, ES; Zicht, R | 1 |
| Hara, T; Hayashida, M; Niijima, T; Umeda, T | 1 |
| Issinger, OG; Rance, AJ; Thönnes, M | 1 |
| Ase, K; Kikkawa, U; Nishizuka, Y; Ogita, K | 1 |
| Bast, RC; Chua, CC; Conkling, PR; Doty, E; Greenberg, CS; Haney, AF; Misukonis, MA; Nadler, P; Weinberg, JB | 1 |
| Boutwell, RK; Cleaveland, JS; Ordman, AB; Simsiman, RC | 1 |
| Nabi, ZF; Zucker-Franklin, D | 1 |
| Chung, T; Kim, YB | 1 |
| Pályi, I | 1 |
| Oh, SK; Ross, S; Walker, J; Zeisel, S | 1 |
| McGinn, MT; Mullin, JM | 1 |
| Ballinari, D; Cattoretti, G; Delia, D; Della Porta, G; Fontanella, E; Polli, N; Traversari, C | 1 |
| Weinstein, IB | 1 |
| Beverstock, GC; Fibbe, WE; Hakvoort, HW; Kluin-Nelemans, JC; van Dierendonck, JH; van Rood, JJ; Willemze, R | 1 |
| Blumenson, L; Krasner, J; Müller, S; Ozer, H | 1 |
| Pryor, WA | 1 |
| Wattenberg, LW | 1 |
| Canellakis, ES; Vitkauskas, GV | 1 |
| Arranto, A; Stenbäck, F | 1 |
| Friesen, HG; Gertler, A; Walker, A | 1 |
35 review(s) available for tetradecanoylphorbol acetate and Neoplasms
| Article | Year |
|---|---|
Carcinogenic aspects of protein phosphatase 1 and 2A inhibitors.
Topics: Animals; Carcinogens; Disease Progression; Enzyme Inhibitors; Humans; Marine Toxins; Mice; Models, Molecular; Neoplasms; Neoplasms, Experimental; Okadaic Acid; Oxazoles; Protein Phosphatase 1; Protein Phosphatase 2; Rats; Skin Neoplasms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2009 |
Noxa: at the tip of the balance between life and death.
Topics: Amino Acid Sequence; Animals; Apoptosis; Child; DNA Damage; Gene Expression Regulation; Humans; Invertebrates; Mice; Mice, Knockout; Molecular Sequence Data; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Neoplasms; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Sequence Alignment; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Vertebrates | 2008 |
Cellular signaling pathways affect the function of ribonucleotide reductase mRNA binding proteins: mRNA stabilization, drug resistance, and malignancy (Review).
Topics: 3' Untranslated Regions; Animals; Drug Resistance, Neoplasm; Humans; Neoplasms; Protein Binding; Protein Kinase C; Ribonucleotide Reductases; RNA-Binding Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Molecular mechanisms of tumor promotion and multistage carcinogenesis.
Topics: Adenosine Triphosphate; Animals; Base Sequence; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Transformation, Neoplastic; ErbB Receptors; Humans; Lyngbya Toxins; Molecular Conformation; Neoplasms; Oncogenes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Receptors, Drug; Receptors, Immunologic; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1983 |
Phorbol myristate acetate: is a tumor promoter acting as a hormone?
Topics: Animals; Calcimycin; Calcium; Chromosomes; Concanavalin A; Cyclic GMP; DNA; Egtazic Acid; Humans; Myristates; Neoplasms; Potassium; Protein Kinase C; Protons; Sodium; Tetradecanoylphorbol Acetate | 1984 |
Epidermal growth factor receptors interact with transforming growth factors produced by certain human tumor cells and are distinct from specific membrane receptors for phorbol and ingenol esters.
Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; ErbB Receptors; Humans; Neoplasms; Peptides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transforming Growth Factors | 1982 |
Prostaglandins and cancer: a review of tumor initiation through tumor metastasis.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cyclooxygenase Inhibitors; DNA; Epoprostenol; Female; Hematopoietic Stem Cells; Humans; Kidney; Male; Mutagens; Neoplasm Metastasis; Neoplasms; Oxidation-Reduction; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Skin; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1981 |
The genotoxic/epigenetic distinction: relevance to cancer policy.
Topics: Animals; Carcinogens; Diethylstilbestrol; DNA; Dose-Response Relationship, Drug; Health Policy; Humans; Mutagens; Neoplasms; Polychlorinated Dibenzodioxins; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; United States; United States Environmental Protection Agency | 1984 |
Role of oxygen radicals in tumor promotion.
Topics: Animals; Antioxidants; Biotransformation; Carcinogens; Catalase; DNA Repair; DNA Replication; Free Radicals; Humans; Lipid Peroxides; Neoplasms; Oxygen; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1984 |
Heterotopic tracheal transplants: techniques and applications.
Topics: Animals; Carcinogens; Cricetinae; Dogs; Epithelial Cells; Lipid Metabolism; Mice; Neoplasms; Polycyclic Compounds; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Trachea; Transplantation, Heterologous | 1984 |
Critical biochemical and regulatory events in malignant transformation in vitro.
Topics: Animals; Benzamides; Cell Transformation, Neoplastic; Cricetinae; DNA Repair; Humans; In Vitro Techniques; Mice; Mutation; Neoplasms; Poly Adenosine Diphosphate Ribose; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; Thyroid Hormones | 1983 |
Free oxygen radicals: necessary contributors to tumor promotion and cocarcinogenesis.
Topics: Animals; Antioxidants; Cocarcinogenesis; DNA; Free Radicals; Mice; Mutation; Neoplasms; Neutrophils; Nutritional Physiological Phenomena; Oxygen; Protease Inhibitors; Tetradecanoylphorbol Acetate | 1983 |
The paradigm of two-stage carcinogenesis: a critical attitude.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Drug Interactions; Hyperplasia; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Nude; Models, Biological; Neoplasms; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Urethane | 1984 |
Relationship of DNA tertiary and quaternary structure to carcinogenic processes.
Topics: Chromatin; DNA; DNA Repair; Humans; Karyotyping; Leukemia, Lymphoid; Nalidixic Acid; Neoplasms; Novobiocin; Nucleic Acid Conformation; Plasmids; Recombination, Genetic; Tetradecanoylphorbol Acetate | 1982 |
Genetic predisposition to cancer in man: in vitro studies.
Topics: Adenoma; Antigens, Neoplasm; Carcinogens; Cell Division; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Cholesterol; Colonic Neoplasms; Cytoskeleton; Disease Susceptibility; Fibroblasts; Fibronectins; Genes, Dominant; Humans; Mitochondria; Mutation; Neoplasms; Rectal Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Potent tumor promoters other than phorbol ester and their significance.
Topics: Alkaloids; Animals; Cell Adhesion; Cell Aggregation; Cell Transformation, Neoplastic; Enzyme Induction; Humans; Isomerism; Lactones; Lyngbya Toxins; Marine Toxins; Mice; Mollusk Venoms; Neoplasms; Ornithine Decarboxylase; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Arachidonic acid transformation and tumor production.
Topics: Animals; Arachidonic Acids; Cells, Cultured; Humans; Hypercalcemia; Immunity; Neoplasms; Prostaglandin Antagonists; Prostaglandins; Tetradecanoylphorbol Acetate | 1981 |
Histopathology of human intraepithelial neoplasia with implications for chemoprevention strategy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Anticarcinogenic Agents; Epithelium; Female; Humans; Mice; Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate; Uterine Cervical Neoplasms | 1993 |
Mechanisms for species differences in receptor-mediated carcinogenesis.
Topics: Animals; Humans; Neoplasms; Polychlorinated Dibenzodioxins; Protein Kinase C; Receptors, Aryl Hydrocarbon; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; Signal Transduction; Species Specificity; Tetradecanoylphorbol Acetate; Transcription Factors | 1995 |
Potential for protein kinase C inhibitors in cancer therapy.
Topics: Animals; Antineoplastic Agents; Bryostatins; DNA Topoisomerases, Type I; Drug Resistance; Enzyme Inhibitors; Humans; Lactones; Macrolides; Neoplasms; Protein Kinase C; Tetradecanoylphorbol Acetate | 1995 |
Adhesion molecules and tumor cell-vasculature interactions: modulation by bioactive lipid molecules.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Cell Adhesion; Cell Adhesion Molecules; Cytoskeletal Proteins; Endothelium, Vascular; Enzyme Activation; Extracellular Matrix; Female; Humans; Isoenzymes; Male; Mice; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Neoplastic Cells, Circulating; Organ Specificity; Protein Kinase C; Tetradecanoylphorbol Acetate; Up-Regulation | 1996 |
Expression genetics: a different approach to cancer diagnosis and prognosis.
Topics: Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Neoplasms; Prognosis; Proteins; Serpins; Tetradecanoylphorbol Acetate | 1998 |
[The proteasome and malignant hemopathies].
Topics: Biomarkers, Tumor; Cell Differentiation; Cell Membrane; Cell Nucleus; Cell Transformation, Neoplastic; Cysteine Endopeptidases; Cytoplasm; Enzyme-Linked Immunosorbent Assay; Hematologic Neoplasms; Humans; L-Lactate Dehydrogenase; Leukemia-Lymphoma, Adult T-Cell; Multienzyme Complexes; Neoplasm Proteins; Neoplasms; Proteasome Endopeptidase Complex; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; U937 Cells; Vitamin D | 2000 |
Tumor initiation and promotion.
Topics: Animals; Carcinogens; Cocarcinogenesis; DNA Repair; Dose-Response Relationship, Drug; Growth Inhibitors; Humans; Hyperplasia; Inflammation; Models, Biological; Mutation; Neoplasms; Phorbols; Tetradecanoylphorbol Acetate | 1978 |
Cocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Transformation, Viral; Cocarcinogenesis; Diet; Gastrointestinal Neoplasms; Hormones; Humans; Liver Neoplasms; Lung Neoplasms; Membranes; Methylcholanthrene; Models, Biological; Neoplasms; Nutritional Physiological Phenomena; Oncogenic Viruses; Propionibacterium acnes; Protein Biosynthesis; Retroviridae; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urinary Bladder Neoplasms; Vitamin A | 1979 |
Neutrophil--mediated cytotoxicity against tumour cells: state of art.
Topics: Antibodies, Neoplasm; Antibody-Dependent Cell Cytotoxicity; Antigens, CD; CD11 Antigens; CD18 Antigens; Cytoplasmic Granules; Cytotoxicity, Immunologic; Humans; Neoplasms; Neutrophils; Receptors, Fc; Respiratory Burst; Tetradecanoylphorbol Acetate | 1992 |
Interaction and distinction of genotoxic and non-genotoxic events in carcinogenesis.
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Humans; Mice; Mutagens; Neoplasms; Risk Factors; Tetradecanoylphorbol Acetate | 1992 |
Clinical significances of superoxide dismutases: changes in aging, diabetes, ischemia, and cancer.
Topics: Aging; Diabetes Mellitus; Female; Humans; Ischemia; Male; Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
Approaches to more effective induction of cytodifferentiation of transformed cells and potential for cancer treatment.
Topics: Acetamides; Animals; Cell Differentiation; Humans; Leukemia, Erythroblastic, Acute; Neoplasms; Oncogenes; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vincristine | 1990 |
Conjugated dienoic derivatives of linoleic acid: mechanism of anticarcinogenic effect.
Topics: Animals; Antioxidants; Cattle; Diet; Humans; Linoleic Acids; Meat; Mutagenesis; Neoplasms; Phospholipids; Tetradecanoylphorbol Acetate | 1990 |
Effects of interferon on differentiation of normal and tumor cells.
Topics: Adipose Tissue; Animals; Cell Differentiation; Cells, Cultured; Dimethyl Sulfoxide; Hematopoiesis; Humans; Interferons; Leukemia; Leukemia, Erythroblastic, Acute; Melanins; Melanoma; Mice; Muscles; Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
[Role of tumor-promotors--mechanisms and inhibition].
Topics: Animals; Carcinogens; Humans; Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
The origins of human cancer: molecular mechanisms of carcinogenesis and their implications for cancer prevention and treatment--twenty-seventh G.H.A. Clowes memorial award lecture.
Topics: Carcinogens; Cell Transformation, Neoplastic; DNA; Environmental Exposure; Gene Amplification; Humans; Models, Biological; Neoplasms; Oncogenes; Polycyclic Compounds; Protein Kinase C; Tetradecanoylphorbol Acetate | 1988 |
Chemoprevention of cancer.
Topics: Animals; Antineoplastic Agents; Biotransformation; Carcinogens; Drug Administration Schedule; Humans; Neoplasms; Neoplasms, Experimental; Skin Neoplasms; Smoking; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1985 |
Intercellular communication and cancer chemotherapy.
Topics: Animals; Antineoplastic Agents; Cell Communication; Humans; In Vitro Techniques; Intercellular Junctions; Neoplasms; Oncogenes; Tetradecanoylphorbol Acetate; Tumor Stem Cell Assay | 1985 |
3 trial(s) available for tetradecanoylphorbol acetate and Neoplasms
| Article | Year |
|---|---|
A phase I clinical trial of 12- O-tetradecanoylphorbol-13-acetate for patients with relapsed/refractory malignancies.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Pharmacodynamic monitoring of BAY 43-9006 (Sorafenib) in phase I clinical trials involving solid tumor and AML/MDS patients, using flow cytometry to monitor activation of the ERK pathway in peripheral blood cells.
Topics: Aged; Aged, 80 and over; Antigens, CD; Antigens, CD34; Antigens, Differentiation, Myelomonocytic; Benzenesulfonates; CD13 Antigens; CD3 Complex; Drug Monitoring; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; Hemolysis; Humans; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; MAP Kinase Signaling System; Middle Aged; Models, Biological; Myelodysplastic Syndromes; Neoplasms; Niacinamide; Phenylurea Compounds; Phosphorylation; Pyridines; Sialic Acid Binding Ig-like Lectin 3; Sorafenib; Stem Cell Factor; Stem Cells; Tetradecanoylphorbol Acetate | 2006 |
Clinical trials with human tumor necrosis factor: in vivo and in vitro effects on human mononuclear phagocyte function.
Topics: Blood Coagulation Factors; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Hydrogen Peroxide; Macrophages; Monocytes; Neoplasms; Phagocytes; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1988 |
155 other study(ies) available for tetradecanoylphorbol acetate and Neoplasms
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Role of the phenolic hydroxyl group in the biological activities of simplified analogue of aplysiatoxin with antiproliferative activity.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Hydroxyl Radical; Lyngbya Toxins; Neoplasms; Protein Kinase C | 2010 |
Pyrrolo[3',2':6,7]cyclohepta[1,2-b]pyridines with potent photo-antiproliferative activity.
Topics: Antineoplastic Agents; Antioxidants; Blotting, Western; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Light; Neoplasms; Photosensitizing Agents; Pyridines; Pyrroles; Reactive Oxygen Species; Structure-Activity Relationship; Tumor Cells, Cultured | 2017 |
Au-Fe
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cell Survival; Drug Carriers; Drug Delivery Systems; Drug Screening Assays, Antitumor; Gold; Humans; Magnetite Nanoparticles; Neoplasms; Particle Size; Tannins; Tetradecanoylphorbol Acetate | 2021 |
A JUN N-terminal kinase inhibitor induces ectodomain shedding of the cancer-associated membrane protease Prss14/epithin via protein kinase CβII.
Topics: Anthracenes; Cell Line, Tumor; Humans; MAP Kinase Kinase 4; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Protein Kinase C beta; Protein Kinase Inhibitors; Protein Transport; Serine Endopeptidases; Signal Transduction; Tetradecanoylphorbol Acetate | 2020 |
Pronounced cancer resistance in a subterranean rodent, the blind mole-rat, Spalax: in vivo and in vitro evidence.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Hepatocellular; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cell Survival; Coculture Techniques; Culture Media, Conditioned; Disease Resistance; DNA Fragmentation; Fibroblasts; Fibrosarcoma; Humans; Liver Neoplasms; Mice; Mitochondrial Dynamics; Neoplasms; Rats; Spalax; Tetradecanoylphorbol Acetate; Tumor Stem Cell Assay | 2013 |
Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis.
Topics: Animals; Basement Membrane; Cell Line, Tumor; Cell Membrane Structures; Cells, Cultured; Endothelial Cells; Green Fluorescent Proteins; HEK293 Cells; HeLa Cells; Humans; Integrin alpha6beta1; Laminin; Lung Neoplasms; Male; Matrix Metalloproteinase 14; Melanoma, Experimental; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Microscopy, Fluorescence; Neoplasms; Neovascularization, Pathologic; RNA Interference; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A | 2014 |
Anti-inflammatory, anti-bacterial, and cytotoxic activity of fibrous clays.
Topics: Aluminum Silicates; Animals; Antacids; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antidotes; Antineoplastic Agents; Cell Survival; Clay; Edema; Humans; Kinetics; Macrophages; Magnesium Compounds; Magnesium Silicates; Male; Mice; Neoplasms; Neutrophils; Peroxidase; Rats; Rats, Wistar; Silicon Compounds; Tetradecanoylphorbol Acetate | 2015 |
The PKC/NF-κB signaling pathway induces APOBEC3B expression in multiple human cancers.
Topics: Cell Line, Tumor; Cytidine Deaminase; Humans; Minor Histocompatibility Antigens; Neoplasms; NF-kappa B p50 Subunit; NF-kappa B p52 Subunit; Papillomavirus Infections; Promoter Regions, Genetic; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Transcription Factor RelB; Transcriptional Activation | 2015 |
TSG101, a tumor susceptibility gene, bidirectionally modulates cell invasion through regulating MMP-9 mRNA expression.
Topics: Cell Line, Tumor; Cell Movement; DNA-Binding Proteins; Endosomal Sorting Complexes Required for Transport; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasms; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors | 2015 |
Total Synthesis and in Vitro Anti-Tumor-Promoting Activities of Racemic Acetophenone Monomers from Acronychia trifoliolata.
Topics: Acetophenones; Antigens, Viral; Carcinogens; Herpesvirus 4, Human; Humans; Molecular Structure; Neoplasms; Rutaceae; Stereoisomerism; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2016 |
Shedding of epidermal growth factor receptor is a regulated process that occurs with overexpression in malignant cells.
Topics: Amino Acid Sequence; Animals; Cattle; Cell Line, Tumor; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Humans; Molecular Sequence Data; Neoplasms; Peptides; Phenylmercuric Acetate; Protease Inhibitors; Protein Isoforms; Protein Kinase C; Protein Structure, Tertiary; Sequence Alignment; Spectrometry, Mass, Electrospray Ionization; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Vanadates | 2008 |
The immunoregulatory protein human B7H3 is a tumor-associated antigen that regulates tumor cell migration and invasion.
Topics: Antigens, CD; Antigens, Neoplasm; Antiviral Agents; B7 Antigens; Binding, Competitive; Blotting, Western; Cell Adhesion; Cell Movement; Cell Proliferation; Collagen; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Fibronectins; Flow Cytometry; Glycosylation; Humans; Immunoprecipitation; Laminin; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Proteoglycans; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tunicamycin | 2008 |
Granulocyte activity in patients with cancer and healthy subjects.
Topics: Case-Control Studies; Cell Count; Female; Fluorescent Dyes; Granulocytes; Humans; Hydrogen Peroxide; Kinetics; Male; NADPH Oxidases; Neoplasms; Oxazines; Reproducibility of Results; Respiratory Burst; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Time Factors | 2008 |
High expression of circadian gene mPer2 diminishes radiosensitivity of tumor cells.
Topics: Animals; Carcinoma, Lewis Lung; Cell Cycle Proteins; Cell Survival; Circadian Rhythm; Cobalt Radioisotopes; DNA Repair; Dose-Response Relationship, Radiation; Gamma Rays; Immunohistochemistry; Mice; Neoplasms; Nuclear Proteins; Period Circadian Proteins; Radiation Tolerance; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Transcription Factors | 2008 |
A novel protein fraction from Sesbania grandiflora shows potential anticancer and chemopreventive efficacy, in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspases; Cell Line; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Enzyme Activation; Flowers; Humans; Male; Mice; Neoplasms; Neoplasms, Experimental; NF-kappa B; Phytotherapy; Plant Extracts; Plant Proteins; Plants, Medicinal; Poly(ADP-ribose) Polymerases; Sesbania; Tetradecanoylphorbol Acetate; Treatment Outcome | 2010 |
Patterns of MMP-2 and MMP-9 expression in human cancer cell lines.
Topics: Cell Line, Tumor; Enzyme Induction; Female; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
A regulatory mechanism for RSK2 NH(2)-terminal kinase activity.
Topics: Binding Sites; Cell Division; Cell Line, Tumor; Cell Transformation, Neoplastic; Epidermal Growth Factor; Humans; Kaempferols; Kinetics; Lysine; Neoplasms; Phosphorylation; Protein Kinases; Recombinant Proteins; Reference Values; Ribosomal Protein S6 Kinases, 90-kDa; Skin; Tetradecanoylphorbol Acetate; Tissue Array Analysis; Valine | 2009 |
The induction of senescence-like growth arrest by protein kinase C-activating diterpene esters in solid tumor cells.
Topics: beta-Galactosidase; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Diterpenes; Down-Regulation; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Activation; Enzyme Activators; Esters; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; Neoplasms; Oligonucleotide Array Sequence Analysis; Phenotype; Phospholipases A2, Calcium-Independent; Protein Kinase C; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Suppressor Proteins | 2010 |
50 Hz extremely low frequency electromagnetic fields enhance protein carbonyl groups content in cancer cells: effects on proteasomal systems.
Topics: Analysis of Variance; Caco-2 Cells; Carcinogens; Catechin; Cell Survival; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Radiation; Electromagnetic Fields; Humans; Neoplasms; Proteasome Endopeptidase Complex; Protein Carbonylation; Radiation-Protective Agents; Temperature; Tetradecanoylphorbol Acetate | 2009 |
Evaluation of peripheral blood neutrophil function in tumor-bearing dogs.
Topics: Animals; Carcinoma; Dog Diseases; Dogs; Flow Cytometry; Leukocyte Count; Lymphoma; Neoplasms; Neutrophils; Phagocytosis; Respiratory Burst; Sarcoma; Tetradecanoylphorbol Acetate | 2010 |
Receptor-binding cancer antigen expressed on SiSo cells induces apoptosis via ectodomain shedding.
Topics: Antigens, Neoplasm; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Coculture Techniques; Female; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; MAP Kinase Signaling System; Neoplasms; Phosphorylation; Signal Transduction; Tetradecanoylphorbol Acetate; Uterine Neoplasms | 2010 |
Hybrids of 3alpha-methoxyserrat-14-en-21beta-ol (PJ-1) and 3beta-methoxyserrat-14-en-21beta-ol (PJ-2) and various anti-oxidants as cancer chemopreventive agents.
Topics: Animals; Antigens, Viral; Antineoplastic Agents; Antioxidants; Cell Line; Drug Screening Assays, Antitumor; Female; Herpesvirus 4, Human; HIV Reverse Transcriptase; HIV-1; Humans; Mice; Mice, Inbred ICR; Neoplasms; Pyrones; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2010 |
Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by apigenin via the inhibition of p38 mitogen-activated protein kinase-dependent matrix metalloproteinase-9 expression.
Topics: Apigenin; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Drug Evaluation, Preclinical; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasms; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2010 |
Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines.
Topics: Antineoplastic Agents, Phytogenic; Ascorbic Acid; Camellia sinensis; Catechin; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Lysine; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Micronutrients; Neoplasm Invasiveness; Neoplasms; Plant Extracts; Proline; Protease Inhibitors; Tetradecanoylphorbol Acetate | 2010 |
Homeobox gene Dlx-2 is implicated in metabolic stress-induced necrosis.
Topics: Antigens, Surface; Apoptosis; Breast Neoplasms; Cell Aggregation; Cell Line, Tumor; Colonic Neoplasms; Female; Gene Expression Profiling; Gene Knockdown Techniques; Glucose; Humans; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membranes; Necrosis; Neoplasms; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Permeability; Reactive Oxygen Species; RNA Interference; Stress, Physiological; Tetradecanoylphorbol Acetate | 2011 |
Nature and dynamics of nucleosome release from neoplastic and non-neoplastic cells.
Topics: Apoptosis; Blast Crisis; Cytarabine; Etoposide; Hep G2 Cells; Humans; L-Lactate Dehydrogenase; Leukemia; Neoplasms; Neutrophils; Nucleosomes; Tetradecanoylphorbol Acetate; TNF-Related Apoptosis-Inducing Ligand | 2012 |
Mediterranean diet polyphenols reduce inflammatory angiogenesis through MMP-9 and COX-2 inhibition in human vascular endothelial cells: a potentially protective mechanism in atherosclerotic vascular disease and cancer.
Topics: Antioxidants; Atherosclerosis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diet, Mediterranean; Gene Expression Regulation, Enzymologic; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Neoplasms; Neovascularization, Pathologic; NF-kappa B; Olive Oil; Plant Oils; Polyphenols; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Wine | 2012 |
Human VRK2 (vaccinia-related kinase 2) modulates tumor cell invasion by hyperactivation of NFAT1 and expression of cyclooxygenase-2.
Topics: Animals; Binding Sites; Cell Line, Tumor; Cyclooxygenase 2; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Intracellular Signaling Peptides and Proteins; Ionomycin; Isoenzymes; Mice; Models, Biological; Muscle Proteins; Neoplasm Invasiveness; Neoplasms; NFATC Transcription Factors; Phosphorylation; Phosphoserine; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Response Elements; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2012 |
Nuclear expression of hypoxia-inducible factor 1alpha protein is heterogeneous in human malignant cells under normoxic conditions.
Topics: Cell Nucleus; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Neoplasms; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 2002 |
Does the release of arachidonic acid from cells play a role in cancer chemoprevention?
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Arachidonic Acid; Catechin; Celecoxib; Cholecalciferol; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Epoprostenol; Humans; Indomethacin; Isoenzymes; Kidney; Liver; Membrane Proteins; Neoplasms; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Retinoids; Sulfonamides; Tetradecanoylphorbol Acetate | 2003 |
Biochemical determination of natural tumor-associated T-cell epitopes.
Topics: Algorithms; Antibodies, Monoclonal; Antigens, CD; Antigens, Neoplasm; Brefeldin A; Chromatography, Affinity; Chromatography, High Pressure Liquid; Databases, Protein; Epitope Mapping; Epitopes, T-Lymphocyte; Flow Cytometry; Histocompatibility Antigens Class I; Humans; Interferon-gamma; Ionomycin; Leukocytes, Mononuclear; Lymphocyte Activation; Neoplasms; Peptide Library; Peptides; Sequence Analysis, Protein; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2003 |
Novel mechanisms of sublethal oxidant toxicity: induction of premature senescence in human fibroblasts confers tumor promoter activity.
Topics: Carcinogens; Cell Adhesion; Cell Communication; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cellular Senescence; Coculture Techniques; Connexin 43; Culture Media, Conditioned; Extracellular Matrix; Fibroblasts; Gap Junctions; Humans; Keratinocytes; Models, Biological; Neoplasms; Oxidants; Oxidative Stress; Tetradecanoylphorbol Acetate; Tumor Stem Cell Assay | 2003 |
Functional imaging of proteolysis: stromal and inflammatory cells increase tumor proteolysis.
Topics: Breast Neoplasms; Carcinoma; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Survival; Coculture Techniques; Collagen; Collagen Type IV; Colonic Neoplasms; Drug Combinations; Endopeptidases; Humans; Hydroxamic Acids; Image Processing, Computer-Assisted; Immunohistochemistry; Laminin; Macrophages; Monocytes; Neoplasms; Proteoglycans; Spheroids, Cellular; Stromal Cells; Tetradecanoylphorbol Acetate; U937 Cells | 2003 |
Benzyl isothiocyanate inhibits excessive superoxide generation in inflammatory leukocytes: implication for prevention against inflammation-related carcinogenesis.
Topics: Anticarcinogenic Agents; Cell Differentiation; Glutathione; HL-60 Cells; Humans; Inflammation; Isothiocyanates; Kinetics; Leukocytes; NADPH Oxidases; Neoplasms; Protein Kinase C; Protein Transport; Superoxides; Tetradecanoylphorbol Acetate | 2004 |
Blockade of cathepsin B expression in human glioblastoma cells is associated with suppression of angiogenesis.
Topics: Angiogenesis Inhibitors; Animals; Biological Assay; Brain Neoplasms; Cathepsin B; Cell Line, Tumor; Cell Movement; Chromones; Culture Media, Conditioned; Culture Media, Serum-Free; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Glioblastoma; Humans; Matrix Metalloproteinase Inhibitors; Mice; Mice, Nude; Morpholines; Neoplasms; Neovascularization, Pathologic; Tetradecanoylphorbol Acetate; Transfection; Vascular Endothelial Growth Factor A | 2004 |
Cancer chemopreventive effects of polyunsaturated fatty acids.
Topics: Animals; Antigens, Viral; Fatty Acids, Unsaturated; Mice; Neoplasms; Nitric Oxide Donors; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate | 2004 |
Synthetic curcumin analogs inhibit activator protein-1 transcription and tumor-induced angiogenesis.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Chick Embryo; Curcumin; Down-Regulation; Humans; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Umbilical Cord; Vascular Endothelial Growth Factor A | 2004 |
Delayed and sustained activation of extracellular signal-regulated kinase in human keratinocytes by UVA: implications in carcinogenesis.
Topics: Animals; Apoptosis; Blotting, Western; Calcium; Carbazoles; Caspase 3; Caspases; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Survival; Cell Transformation, Neoplastic; Chelating Agents; COS Cells; Cytosol; Dose-Response Relationship, Radiation; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Estrenes; Flow Cytometry; Genes, Dominant; Golgi Apparatus; Humans; Indoles; Keratinocytes; Mitogen-Activated Protein Kinase 3; Models, Biological; Neoplasms; Plasmids; Protein Kinase C; Pyrrolidinones; ras Proteins; Skin Neoplasms; Subcellular Fractions; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Ultraviolet Rays | 2004 |
Tumor cell-mediated induction of the stromal factor stromelysin-3 requires heterotypic cell contact-dependent activation of specific protein kinase C isoforms.
Topics: Cell Adhesion; Cell Line; Cell Line, Tumor; Cell Membrane; Coculture Techniques; Enzyme Activation; Enzyme Induction; Fibroblasts; Green Fluorescent Proteins; Humans; Isoenzymes; Matrix Metalloproteinase 11; Metalloendopeptidases; Neoplasms; Protein Kinase C; Protein Transport; Signal Transduction; Tetracycline; Tetradecanoylphorbol Acetate | 2005 |
Ras-dependent induction of HIF-1alpha785 via the Raf/MEK/ERK pathway: a novel mechanism of Ras-mediated tumor promotion.
Topics: Animals; Cell Line; DNA-Binding Proteins; Enzyme Induction; Enzyme Inhibitors; Genes, ras; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Neoplasms; Nuclear Proteins; Tetradecanoylphorbol Acetate; Transcription Factors | 2004 |
The telomerase RNA component Terc is required for the tumour-promoting effects of Tert overexpression.
Topics: Animals; Cell Transformation, Neoplastic; Chromosomal Instability; Chromosome Aberrations; DNA-Binding Proteins; Gene Deletion; In Situ Hybridization, Fluorescence; Keratinocytes; Mice; Mice, Knockout; Mutation; Neoplasms; Protein Subunits; RNA; Skin Neoplasms; Telomerase; Tetradecanoylphorbol Acetate; Wound Healing | 2005 |
Receptors and lytic mediators regulating anti-tumor activity by the leukemic killer T cell line TALL-104.
Topics: Adoptive Transfer; Antibodies, Monoclonal; Antigens, CD; Apoptosis Regulatory Proteins; Carcinogens; CD3 Complex; Cell Degranulation; Cytotoxicity, Immunologic; Fas Ligand Protein; Histocompatibility Antigens Class I; Humans; Immediate-Early Proteins; Ionomycin; Ionophores; Jurkat Cells; Killer Cells, Natural; Lymphocyte Activation; Membrane Glycoproteins; Monomeric GTP-Binding Proteins; Natural Cytotoxicity Triggering Receptor 1; Neoplasms; NK Cell Lectin-Like Receptor Subfamily C; NK Cell Lectin-Like Receptor Subfamily K; Receptors, Immunologic; Receptors, KIR; Receptors, KIR3DL2; Receptors, Natural Killer Cell; Signal Transduction; Signaling Lymphocytic Activation Molecule Family; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Tumor Necrosis Factors; U937 Cells | 2005 |
Global genomic changes induced by two-stage carcinogen exposure are precancerous alterations in non-transformed human liver epithelial THLE-3 cells.
Topics: Benzo(a)pyrene; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 17; DNA; DNA Damage; G1 Phase; Gene Expression Regulation, Neoplastic; Genome, Human; Genotype; Humans; In Situ Hybridization, Fluorescence; Laser Scanning Cytometry; Liver; Methylnitronitrosoguanidine; Neoplasms; Nucleic Acid Hybridization; Phenotype; Ploidies; Resting Phase, Cell Cycle; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Tumour-derived microvesicles carry several surface determinants and mRNA of tumour cells and transfer some of these determinants to monocytes.
Topics: Adenocarcinoma; Antigens, Neoplasm; Apoptosis; Basigin; Cell Line, Tumor; Cell Membrane; Cell Survival; Chemotaxis; Colorectal Neoplasms; Gene Expression Profiling; Genes, MHC Class I; HLA Antigens; Humans; Hyaluronan Receptors; Immunophenotyping; Lung Neoplasms; Membrane Proteins; Monocytes; Neoplasm Proteins; Neoplasms; Pancreatic Neoplasms; Particle Size; Receptors, Chemokine; Receptors, Cytokine; RNA, Messenger; Tetradecanoylphorbol Acetate | 2006 |
Detection of Epstein-Barr virus infection and gene expression in human tumors by microarray analysis.
Topics: B-Lymphocytes; Burkitt Lymphoma; Butyrates; Cell Line, Tumor; DNA, Viral; Epstein-Barr Virus Infections; Evaluation Studies as Topic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Viral; Genes, Viral; Genome, Viral; Herpesvirus 4, Human; Humans; Microarray Analysis; Neoplasms; RNA, Messenger; Tetradecanoylphorbol Acetate | 2006 |
Protein tyrosine phosphatase PRL-3 in malignant cells and endothelial cells: expression and function.
Topics: Endothelial Cells; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Humans; Neoplasms; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Salivary Proteins and Peptides; Tetradecanoylphorbol Acetate; Up-Regulation | 2006 |
Ursolic acid enhances cyclooxygenases and tumor necrosis factor-alpha expression in mouse skin.
Topics: Animals; Carcinogenicity Tests; Cyclooxygenase 1; Cyclooxygenase 2; Gene Expression Regulation; Inflammation Mediators; Mice; Mice, Inbred ICR; Neoplasms; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Triterpenes; Tumor Necrosis Factor-alpha; Ursolic Acid | 2006 |
Sustained activation of protein kinase C downregulates nuclear factor-kappaB signaling by dissociation of IKK-gamma and Hsp90 complex in human colonic epithelial cells.
Topics: Blotting, Western; Cell Death; Cells, Cultured; Colon; Epithelial Cells; HSP90 Heat-Shock Proteins; Humans; I-kappa B Kinase; Immunoenzyme Techniques; Immunoprecipitation; Kidney; Luciferases; Neoplasms; NF-kappa B; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 2007 |
Inhibitory effect of ailanthoidol on 12-O-tetradecanoyl-phorbol-13-acetate-induced tumor promotion in mouse skin.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Benzo(a)pyrene; Benzofurans; Carcinogens; Female; Mice; Mice, Inbred ICR; Neoplasms; Peroxidase; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2006 |
Isodeoxyelephantopin, a novel sesquiterpene lactone, potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis through suppression of nuclear factor-kappaB (nf-kappaB) activation and nf-kappaB-regulated gene expression.
Topics: Apoptosis; Blotting, Western; Cell Differentiation; Cell Movement; Electrophoretic Mobility Shift Assay; Enzyme Activation; Humans; I-kappa B Kinase; I-kappa B Proteins; Immunoprecipitation; Interleukin-1; Lactones; Lipopolysaccharides; Neoplasms; NF-kappa B; NF-KappaB Inhibitor alpha; Osteoclasts; Phosphorylation; Sesquiterpenes; Terpenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2006 |
Methyl-3-indolylacetate inhibits cancer cell invasion by targeting the MEK1/2-ERK1/2 signaling pathway.
Topics: Cell Line, Tumor; HeLa Cells; Humans; Indoleacetic Acids; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinase 2; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Neoplasms; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transfection | 2006 |
Transplacental arsenic carcinogenesis in mice.
Topics: Animals; Anticarcinogenic Agents; Arsenic; Arsenicals; Carcinogens; Carcinoma, Transitional Cell; Data Interpretation, Statistical; Diethylstilbestrol; Dose-Response Relationship, Drug; Drug Synergism; Estrogens; Female; Gene Expression Regulation, Neoplastic; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred C3H; Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Signal Transduction; Skin Neoplasms; Tamoxifen; Tetradecanoylphorbol Acetate; Urinary Bladder Neoplasms | 2007 |
JWA as a functional molecule to regulate cancer cells migration via MAPK cascades and F-actin cytoskeleton.
Topics: Actins; Amino Acid Motifs; Amino Acid Sequence; Arsenic Trioxide; Arsenicals; Base Sequence; Cell Movement; Cyclooxygenase 2; Cytoskeleton; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Kinase 1; Heat-Shock Proteins; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 1; MAP Kinase Signaling System; Membrane Transport Proteins; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Neoplasms; Oxides; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate | 2007 |
Different gene expression of skin tissues between mice with weight controlled by either calorie restriction or physical exercise.
Topics: Animals; Caloric Restriction; Carcinogens; Energy Metabolism; Female; Gene Expression Profiling; Gene Expression Regulation; Mice; Neoplasms; Oligonucleotide Array Sequence Analysis; Physical Conditioning, Animal; Risk Factors; Skin; Tetradecanoylphorbol Acetate; Weight Loss | 2007 |
Equol, a metabolite of the soybean isoflavone daidzein, inhibits neoplastic cell transformation by targeting the MEK/ERK/p90RSK/activator protein-1 pathway.
Topics: Animals; Binding Sites; Cell Line; Epidermal Growth Factor; Equol; Extracellular Signal-Regulated MAP Kinases; Glycine max; Isoflavones; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mice; Models, Molecular; Molecular Structure; Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-fos; ras Proteins; Replication Protein C; Ribosomal Protein S6 Kinases, 90-kDa; Tetradecanoylphorbol Acetate | 2007 |
Suppression of PMA-induced tumor cell invasion by capillarisin via the inhibition of NF-kappaB-dependent MMP-9 expression.
Topics: Cell Line, Tumor; Chromones; Collagen; Drug Combinations; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Laminin; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Neoplasm Invasiveness; Neoplasms; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Proteoglycans; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation | 2008 |
Galectin-3 regulates RasGRP4-mediated activation of N-Ras and H-Ras.
Topics: Animals; Blotting, Western; Cricetinae; Epidermal Growth Factor; Galectin 3; Genes, ras; Guanosine Triphosphate; Humans; Immunoprecipitation; Neoplasms; ras Guanine Nucleotide Exchange Factors; ras Proteins; Rats; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2008 |
ERK signaling regulates tumor promoter induced c-Jun recruitment at the Fra-1 promoter.
Topics: Fos-Related Antigen-2; Gene Expression Regulation, Neoplastic; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasms; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Response Elements; Serum Response Element; Signal Transduction; Tetradecanoylphorbol Acetate | 2008 |
Reduced susceptibility to two-stage skin carcinogenesis in mice with low circulating insulin-like growth factor I levels.
Topics: Animals; Benz(a)Anthracenes; Cell Proliferation; Cell Transformation, Neoplastic; Epidermis; Female; Genetic Predisposition to Disease; Insulin-Like Growth Factor I; Mice; Models, Biological; Neoplasms; Protein Kinases; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases | 2008 |
Phorbol ester-induced threonine phosphorylation of the human epidermal growth factor receptor occurs within the EGF binding domain.
Topics: Binding Sites; Cell Line; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; ErbB Receptors; Humans; Models, Biological; Neoplasms; Peptide Fragments; Phorbols; Phosphorylation; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Threonine; Trypsin | 1984 |
Irritant diterpene ester promoters of mouse skin: contributions to etiologies of environmental cancer and to biochemical mechanisms of carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Affinity Labels; Animals; Biotransformation; Caenorhabditis elegans Proteins; Carcinogens, Environmental; Carrier Proteins; Diterpenes; Electron Spin Resonance Spectroscopy; Humans; Irritants; Mice; Neoplasms; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Skin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1983 |
Release of histamine from human leukocytes stimulated with the tumor-promoting phorbol diesters. I. Characterization of the response.
Topics: Antibodies, Anti-Idiotypic; Calcium; Colchicine; Cyclic AMP; Deoxyglucose; Histamine Release; Humans; Immunoglobulin E; Leukocytes; Neoplasms; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Prevention of interferon-induced augmentation of cellular antitumor effector mechanisms by phorbol esters.
Topics: Animals; Interferons; Killer Cells, Natural; Macrophages; Mice; Mice, Inbred Strains; Neoplasms; Phorbols; Tetradecanoylphorbol Acetate; Virus Replication | 1982 |
Effects of 12-O-tetradecanoylphorbol-13-acetate on fibroblasts from individuals genetically predisposed to cancer.
Topics: Cell Adhesion; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cytoskeleton; Disease Susceptibility; Down Syndrome; Epidermal Growth Factor; Fanconi Anemia; Female; Fibroblasts; Humans; Intestinal Polyps; Male; Neoplasms; Phorbols; Tetradecanoylphorbol Acetate; Trypsin; Xeroderma Pigmentosum | 1982 |
Stimulation of human polymorphonuclear leukocyte superoxide anion radical production by tumor promoters.
Topics: Humans; In Vitro Techniques; Neoplasms; Neutrophils; Oxygen; Phorbols; Superoxides; Tetradecanoylphorbol Acetate | 1981 |
Aminoacyl fucosides as possible biochemical markers at tumorigenic and metastatic potential in herpes simplex virus type 2-transformed rat cells.
Topics: Aminoglycosides; Animals; Cell Line; Cell Transformation, Viral; Chromatography, Thin Layer; Disease Susceptibility; Fucose; Neoplasms; Precancerous Conditions; Rats; Simplexvirus; Tetradecanoylphorbol Acetate | 1981 |
Metabolic heterogeneity of eosinophils from normal and hypereosinophilic patients.
Topics: Eosinophilia; Eosinophils; Hexosephosphates; Humans; Leukemia; Lymphoma; Neoplasms; Sezary Syndrome; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Secretion of oxygen intermediates: role in effector functions of activated macrophages.
Topics: Animals; Antibodies, Neoplasm; Candida; Catalase; Eukaryota; Glutathione; Hydrogen Peroxide; Macrophage Activation; Mice; Neoplasms; Oxygen; Peroxidases; Superoxides; Tetradecanoylphorbol Acetate | 1982 |
Stimulated human phagocytes produce cytogenetic changes in cultured mammalian cells.
Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Crossing Over, Genetic; Female; Humans; Inflammation; Neoplasms; Ovary; Oxygen; Phagocytes; Sister Chromatid Exchange; Superoxides; Tetradecanoylphorbol Acetate | 1983 |
Skin tumor formation in the European hamster (Cricetus cricetus L.) after topical initiation with 7,12-dimethylbenz[a]anthracene (DMBA) and promotion with 12-O-tetradecanoylphorbol-13-acetate (TPA).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cricetinae; Drug Synergism; Female; Male; Neoplasms; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1984 |
Essential function deficiency as the result of tumor promotion and the establishment of biological autarchy.
Topics: Cocarcinogenesis; Disease Susceptibility; Humans; Neoplasms; Phenotype; Phorbols; Tetradecanoylphorbol Acetate; Vitamin A; Vitamin A Deficiency | 1983 |
Intercellular communication, cell differentiation and tumour promotion.
Topics: Amnion; Animals; Carcinogens; Cell Communication; Cell Differentiation; Cells, Cultured; Electric Conductivity; Female; Friend murine leukemia virus; Humans; Leukemia, Erythroblastic, Acute; Mice; Mice, Inbred BALB C; Neoplasms; Phorbol Esters; Phorbols; Pregnancy; Tetradecanoylphorbol Acetate | 1984 |
Regulation of myelopoiesis in vitro: partial replacement of colony-stimulating factors by tumor-promoting phorbol esters.
Topics: Animals; Bone Marrow Cells; Colony-Stimulating Factors; Dose-Response Relationship, Drug; Glycoproteins; Hematopoiesis; Mice; Neoplasms; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1981 |
Effects of 12-O-tetradecanoylphorbol-13-acetate and mezerein on gamma radiation-induced DNA repair in resting bovine lymphocytes.
Topics: Animals; Cattle; Cells, Cultured; Centrifugation, Density Gradient; Dimethyl Sulfoxide; Diterpenes; DNA; DNA Repair; Gamma Rays; Interphase; Lymphocytes; Neoplasms; Phorbol Esters; Phorbols; Terpenes; Tetradecanoylphorbol Acetate | 1982 |
Tumor-promoting diterpene esters prevent macrophage activation and suppress macrophage tumoricidal capacity.
Topics: Animals; Carcinogens; Diterpenes; Killer Cells, Natural; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Neoplasms; Phorbol Esters; Rats; Tetradecanoylphorbol Acetate | 1982 |
[Cocarcinogen as a factor increasing the incidence of mutation responsible for cellular resistance to antifolates].
Topics: Animals; Cell Survival; Cells, Cultured; Cocarcinogenesis; Drug Resistance; Genes; Humans; Methotrexate; Mice; Mutation; Neoplasms; Phorbols; Tetradecanoylphorbol Acetate; Tetrahydrofolate Dehydrogenase | 1982 |
Prostaglandins and cancer: further stereochemical studies on the molecule of phospholipase A2.
Topics: Animals; Binding, Competitive; Mice; Neoplasms; Phospholipases; Phospholipases A; Phospholipases A2; Prostaglandins E; Receptors, Prostaglandin; Stereoisomerism; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
Immunorestoration of anergic cancer patients by azimexon.
Topics: Adjuvants, Immunologic; Aziridines; Azirines; Humans; Hypersensitivity, Delayed; Immunotherapy; Lymphocytes; Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Phorbol ester dramatically increases incidence of methotrexate-resistant mouse cells: possible mechanisms and relevance to tumor promotion.
Topics: Animals; Cell Count; Cell Division; Cell Line; Clone Cells; Dose-Response Relationship, Drug; Drug Resistance; Gene Amplification; Methotrexate; Mice; Neoplasms; Phorbols; Tetradecanoylphorbol Acetate; Tetrahydrofolate Dehydrogenase | 1981 |
Retinoic acid analogues. Synthesis and potential as cancer chemopreventive agents.
Topics: Animals; Epidermis; Female; Mice; Neoplasms; Neoplasms, Experimental; Ornithine Decarboxylase Inhibitors; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
[2-Step carcinogenesis. Significance of tumor promotors in the development of cancer].
Topics: Adenine Nucleotides; Carcinogens; Carcinogens, Environmental; DNA, Neoplasm; Humans; Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Inhibitory effects of steroidal saponins on 12-O-tetradecanoylphorbol-13-acetate (TPA)-enhanced 32P-incorporation into phospholipids of HeLa cells and proliferation of human malignant tumor cells.
Topics: Carbohydrate Sequence; Cell Division; Drug Interactions; HeLa Cells; Humans; Molecular Sequence Data; Neoplasms; Phospholipids; Phosphorus; Phosphorus Radioisotopes; Saponins; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Differential expression of TIS21 and TIS1 genes in the various organs of Balb/c mice, thymic carcinoma tissues and human cancer cell lines.
Topics: Animals; Gene Expression Regulation; Genes, Tumor Suppressor; Humans; Immediate-Early Proteins; Mice; Mice, Inbred BALB C; Neoplasms; Proteins; Tetradecanoylphorbol Acetate; Thymus Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1995 |
Defective cytokine production following autologous stem cell transplantation for solid tumors and hematologic malignancies regardless of bone marrow or peripheral origin and lack of evidence for a role for interleukin-10 in delayed immune reconstitution.
Topics: Adolescent; Adult; Bone Marrow Cells; CD28 Antigens; Cytokines; Hematopoietic Stem Cell Transplantation; Humans; Interleukin-10; Interleukin-2; Middle Aged; Neoplasms; Phytohemagglutinins; Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transplantation, Autologous | 1994 |
Myeloid activation antigen CD66/67: immunochemical and immunocytometric characterization with the Vth workshop monoclonal antibodies.
Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation; Antigens, Neoplasm; Cell Adhesion Molecules; Down-Regulation; Flow Cytometry; Fluorometry; Hematopoietic System; Humans; Immunohistochemistry; Leukemia, Myeloid; Membrane Glycoproteins; Molecular Weight; Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Inhibition of apoptosis as a mechanism of tumor promotion.
Topics: Animals; Apoptosis; Carcinogens; DDT; Diethylstilbestrol; Leukemia P388; Leukemia, Promyelocytic, Acute; Lymphoma, Large B-Cell, Diffuse; Mice; Neoplasms; Saccharin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Ultraviolet Rays | 1994 |
Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells.
Topics: Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carrier Proteins; Daunorubicin; Doxorubicin; Drug Resistance; Etoposide; Genistein; Humans; Hydrogen-Ion Concentration; Isoflavones; Lung Neoplasms; Membrane Glycoproteins; Neoplasms; Protein-Tyrosine Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Induction and down-regulation of PLK, a human serine/threonine kinase expressed in proliferating cells and tumors.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Division; Cycloheximide; DNA, Complementary; DNA, Neoplasm; Down-Regulation; Drosophila Proteins; Enzyme Induction; Gene Expression; Humans; In Vitro Techniques; Lipopolysaccharides; Macrophages; Mice; Molecular Sequence Data; Neoplasms; Protein Serine-Threonine Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate | 1994 |
A protein produced by a monocytic human cell line can induce apoptosis on tumor cells.
Topics: Apoptosis; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Culture Media, Conditioned; Cytokines; Dimethyl Sulfoxide; Humans; Macrophages; Monocytes; Neoplasms; Protein Biosynthesis; Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Inhibition of tumour promotion by various palm-oil tocotrienols.
Topics: Anticarcinogenic Agents; Antigens, Viral; Butyrates; Butyric Acid; Cell Transformation, Viral; Genome, Viral; Herpesvirus 4, Human; Humans; Lymphocytes; Neoplasms; Palm Oil; Plant Oils; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vitamin E | 1994 |
1,25-Dihydroxy vitamin D3 and 12-O-tetradecanoyl phorbol-13-acetate synergistically induce monocytic cell differentiation: FOS and RB expression.
Topics: Antigens, Differentiation, Myelomonocytic; Calcitriol; Cell Differentiation; Cells, Cultured; Drug Synergism; Humans; In Vitro Techniques; Monocytes; Neoplasms; Phagocytosis; Proto-Oncogene Proteins c-fos; Retinoblastoma Protein; Tetradecanoylphorbol Acetate | 1993 |
Inhibitory effects of 3'-methyl-3-hydroxy-chalcone on proliferation of human malignant tumor cells and on skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Chalcone; Chalcones; Dose-Response Relationship, Drug; HeLa Cells; Humans; Mice; Neoplasm Proteins; Neoplasms; Papilloma; Phosphorylation; Skin Neoplasms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1993 |
Analysis of the gene that encodes the complement regulatory protein, membrane inhibitor of reactive lysis (CD59). Identification of an alternatively spliced exon and characterization of the transcriptional regulatory regions of the promoter.
Topics: Antigens, Neoplasm; CD59 Antigens; DNA, Complementary; Exons; Gene Expression Regulation, Neoplastic; Genes; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocytes, Mononuclear; Neoplasms; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA Splicing; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1996 |
VEGF mRNA is reversibly stabilized by hypoxia and persistently stabilized in VEGF-overexpressing human tumor cell lines.
Topics: Animals; Blotting, Northern; Cycloheximide; Endothelial Growth Factors; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Lymphokines; Neoplasms; Oxygen; Partial Pressure; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1995 |
Tumor cell-endothelial cell interactions: evidence for roles for lipoxygenase products of arachidonic acid in metastasis.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Calcimycin; Cattle; Cell Adhesion; Endothelium, Vascular; Humans; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; Neoplasm Metastasis; Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Tissue and differentiation specific expression on the endogenous retrovirus ERV3 (HERV-R) in normal human tissues and during induced monocytic differentiation in the U-937 cell line.
Topics: Cell Differentiation; Cell Line; Cholecalciferol; Cytokines; Female; Gene Expression Regulation, Viral; Gene Products, env; Genes, env; Humans; Male; Monocytes; Neoplasms; Organ Specificity; Pregnancy; Reference Values; Retroviridae; Tetradecanoylphorbol Acetate; Tretinoin | 1997 |
Conjugated linoleic acid modulation of phorbol ester-induced events in murine keratinocytes.
Topics: Animals; Arachidonic Acids; Carcinogens; Cell Line; Drug Interactions; Keratinocytes; Linoleic Acids; Mice; Neoplasms; Ornithine Decarboxylase; Phospholipids; Prostaglandins E; Tetradecanoylphorbol Acetate | 1997 |
12-O-Tetradecanoylphorbol-13-acetate (TPA)-induced increase in depressed white blood cell counts in patients treated with cytotoxic cancer chemotherapeutic drugs.
Topics: Antineoplastic Agents; Dose-Response Relationship, Drug; Humans; Leukocyte Count; Neoplasms; Neutrophils; Tetradecanoylphorbol Acetate | 1998 |
Cyclosporin A inhibits Ca2+-mediated upregulation of the DNA repair enzyme DNA polymerase beta in human peripheral blood mononuclear cells.
Topics: Animals; Base Sequence; Calcineurin; Calcium; Cyclosporine; DNA Polymerase beta; DNA Primers; DNA Repair; Humans; Immunosuppressive Agents; In Vitro Techniques; Ionomycin; Ionophores; Leukocytes, Mononuclear; Neoplasms; RNA, Messenger; Tacrolimus; Tetradecanoylphorbol Acetate; Up-Regulation | 1999 |
Anti-tumor promoting potential of naturally occurring diarylheptanoids structurally related to curcumin.
Topics: 3T3 Cells; Animals; Brain; Carcinogens; Curcumin; Diarylheptanoids; Guaiacol; HL-60 Cells; Humans; In Vitro Techniques; Lipid Peroxidation; Male; Mice; Neoplasms; Ornithine Decarboxylase Inhibitors; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Superoxides; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 1999 |
Apoptosis and the cell cycle in Xenopus laevis: PHA and PMA exposure of splenocytes.
Topics: Animals; Apoptosis; Carcinogens; Cell Cycle; Lymphocytes; Neoplasms; Phytohemagglutinins; Species Specificity; Spleen; Tetradecanoylphorbol Acetate; Xenopus laevis | 1999 |
Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1.
Topics: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Catalytic Domain; Cell Differentiation; DNA-Binding Proteins; Down-Regulation; Gene Expression Regulation; Half-Life; Histone Deacetylases; Humans; Kinetics; Neoplasms; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; Repressor Proteins; Response Elements; RNA; RNA Stability; RNA, Messenger; Saccharomyces cerevisiae Proteins; Sequence Deletion; Telomerase; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transfection; Tretinoin; U937 Cells | 2000 |
Cancer chemopreventive agents, labdane diterpenoids from the stem bark of Thuja standishii (Gord.) Carr.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; beta Carotene; Carboxylic Acids; Carcinogens; Diterpenes; Female; Humans; Mice; Mice, Inbred ICR; Naphthalenes; Nasopharyngeal Neoplasms; Neoplasms; Papilloma; Plant Extracts; Plant Stems; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trees | 2000 |
Inhibition of epstein-barr virus early antigen activation promoted by 12-O-tetradecanoylphorbol-13-acetate by the non-steroidal anti-inflammatory drugs.
Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Viral; Benzene; Carcinogens; Carcinoma; Cell Survival; Etodolac; Fluorescent Antibody Technique, Indirect; Humans; Nasopharyngeal Neoplasms; Neoplasms; Oxidation-Reduction; Salicylates; Structure-Activity Relationship; Sulindac; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
Capsaicin suppresses phorbol ester-induced activation of NF-kappaB/Rel and AP-1 transcription factors in mouse epidermis.
Topics: Animals; Binding, Competitive; Blotting, Western; Capsaicin; Cell Nucleus; Cytoplasm; DNA; Epidermis; Female; I-kappa B Kinase; Mice; Mice, Inbred ICR; Neoplasms; NF-kappa B; Phorbol Esters; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-rel; Skin; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transcription Factor RelA | 2001 |
Suppressive effects of citrus fruits on free radical generation and nobiletin, an anti-inflammatory polymethoxyflavonoid.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Cell Line; Citrus; Flavones; Flavonoids; Free Radicals; HL-60 Cells; Humans; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred ICR; Neoplasms; Nitric Oxide; Superoxides; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase | 2000 |
Peroxisome proliferator-activated receptor gamma ligands suppress the transcriptional activation of cyclooxygenase-2. Evidence for involvement of activator protein-1 and CREB-binding protein/p300.
Topics: Arthritis; Base Sequence; Cell Line; CREB-Binding Protein; Cyclooxygenase 2; Dinoprostone; DNA Primers; Enzyme Induction; Humans; Isoenzymes; Ligands; Membrane Proteins; Neoplasms; Nuclear Proteins; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Receptors, Cytoplasmic and Nuclear; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factor AP-1; Transcription Factors; Transcriptional Activation | 2001 |
Novel tumor-promoting property of tamoxifen.
Topics: Animals; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Down-Regulation; Endometrial Neoplasms; Estradiol Congeners; Female; Fibroblasts; Gene Expression Regulation, Neoplastic; Genes, src; Humans; Neoplasms; Protein Kinase C; Protein Kinase C-delta; Rats; Tamoxifen; Tetradecanoylphorbol Acetate | 2001 |
Phorbol ester tumour promoter mediated altered expression and regulation of matrix metalloproteinase-2 in a H-ras transformed cell line capable of benign tumour formation.
Topics: Animals; Blotting, Northern; Carcinogens; Cell Line, Transformed; Electrophoresis; Gene Expression Regulation, Neoplastic; Genes, ras; Immunoblotting; Matrix Metalloproteinase 2; Mice; Neoplasms; Phorbol Esters; Protein Binding; Protein Kinase C; Protein Synthesis Inhibitors; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
Soy isoflavonoids and cancer -- metabolism at the target site.
Topics: Anticarcinogenic Agents; Chromatography, Liquid; Dose-Response Relationship, Drug; Genistein; Humans; Hypochlorous Acid; Isoflavones; Male; Mass Spectrometry; Middle Aged; Neoplasms; Neutrophils; Respiratory Burst; Tetradecanoylphorbol Acetate; Urine | 2001 |
Ceramide mediates tumor-induced dendritic cell apoptosis.
Topics: Animals; Apoptosis; bcl-X Protein; Caspases; Cells, Cultured; Ceramides; Culture Media, Conditioned; Dendritic Cells; Lymphocyte Culture Test, Mixed; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Neoplasms; NF-kappa B; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Receptors, Interleukin; Receptors, Interleukin-12; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Escape | 2001 |
Anti-tumor promoting effects of multiflorane-type triterpenoids and cytotoxic activity of karounidiol against human cancer cell lines.
Topics: Anticarcinogenic Agents; Antigens, Viral; Cucurbitaceae; Drug Screening Assays, Antitumor; Humans; Neoplasms; Seeds; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Triterpenes; Tumor Cells, Cultured | 2001 |
Cancer chemopreventive activity of phenylpropanoid esters of sucrose, vanicoside B and lapathoside A, from Polygonum lapathifolium.
Topics: Animals; Anticarcinogenic Agents; Cinnamates; Disaccharides; Dose-Response Relationship, Drug; Esters; Female; Mice; Mice, Inbred ICR; Models, Chemical; Neoplasms; Nitric Oxide Donors; Sucrose; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties.
Topics: Antigens, Neoplasm; Apoptosis; Base Sequence; Carcinoma; Cell Differentiation; Cell Division; Chromosomes, Human, Pair 1; Cloning, Molecular; Dimethyl Sulfoxide; Diterpenes; Female; Gene Expression Regulation, Neoplastic; Genes; Genes, Tumor Suppressor; Glioblastoma; Growth Substances; HL-60 Cells; Humans; Interferon Type I; Interleukins; K562 Cells; Male; Melanocytes; Melanoma; Molecular Sequence Data; Molecular Weight; Neoplasm Proteins; Neoplasms; Organ Specificity; Osteosarcoma; Recombinant Fusion Proteins; Recombinant Proteins; RNA, Messenger; RNA, Neoplasm; Terpenes; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 2001 |
Constituents of Compositae plants III. Anti-tumor promoting effects and cytotoxic activity against human cancer cell lines of triterpene diols and triols from edible chrysanthemum flowers.
Topics: Anticarcinogenic Agents; Antigens, Viral; Cell Survival; Chrysanthemum cinerariifolium; Drug Screening Assays, Antitumor; Humans; Neoplasms; Plant Extracts; Plants, Edible; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Triterpenes; Tumor Cells, Cultured | 2002 |
Antitumor activity of the selective epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) Iressa (ZD1839) in an EGFR-expressing multidrug-resistant cell line in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Cell Division; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; ErbB Receptors; Female; Gefitinib; Humans; K562 Cells; Kinetics; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms; Phosphorylation; Quinazolines; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2002 |
Inhibitory effect of herbal remedies on 12-O-tetradecanoylphorbol-13-acetate-promoted Epstein-Barr virus early antigen activation.
Topics: Antigens, Viral; Antineoplastic Agents, Phytogenic; Cell Line; Cell Survival; Chemoprevention; Herpesvirus 4, Human; Humans; Neoplasms; Phytotherapy; Plant Extracts; Tetradecanoylphorbol Acetate; Virus Activation | 2002 |
Iron augments stage-I and stage-II tumor promotion in murine skin.
Topics: Animals; Antioxidants; Benzene Derivatives; Benzoyl Peroxide; Carcinogens; Catalase; DNA; Epidermis; Glutathione; Glutathione Peroxidase; Hydrogen Peroxide; Iron; Lipopolysaccharides; Mice; Microsomes; Neoplasms; Oxidative Stress; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Time Factors | 2002 |
Tumor promoters: carcinogenesis gets more complicated.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Dietary Fats; Epidermal Growth Factor; Humans; Neoplasms; Ornithine Decarboxylase; Phenobarbital; Plasminogen Activators; Receptors, Drug; Saccharin; Smoking; Tetradecanoylphorbol Acetate | 1978 |
The structural relationship of phorbol and cortisol: a possible mechanism for the tumor promoting activity of phorbol.
Topics: Hydrocortisone; Models, Molecular; Neoplasms; Phorbols; Receptors, Glucocorticoid; Tetradecanoylphorbol Acetate | 1976 |
Effect of phorbol ester and cytokines on matrix metalloproteinase and tissue inhibitor of metalloproteinase expression in tumor and normal cell lines.
Topics: Base Sequence; Blotting, Northern; Collagenases; Cycloheximide; Endothelium, Vascular; Fibroblasts; Glycoproteins; Humans; Interleukin-1; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Metalloendopeptidases; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Protein Kinase C; Proto-Oncogene Proteins c-jun; RNA; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinases; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1992 |
Expression of genes encoding type IV collagen-degrading metalloproteinases and tissue inhibitors of metalloproteinases in various human tumor cells.
Topics: Cell Transformation, Neoplastic; Fibroblasts; Gene Expression Regulation, Enzymologic; Glycoproteins; Humans; Matrix Metalloproteinase 9; Microbial Collagenase; Neoplasms; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases; Tumor Cells, Cultured | 1992 |
An enzyme-linked immunosorbent assay for p65 oncofetal protein and its potential as a new marker for cancer risk assessment in rodents and humans.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Choline; Choline Deficiency; Diethylnitrosamine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Neoplasms; Oncogene Proteins; Rats; Rats, Inbred Strains; Risk Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Tumor necrosis factor stimulates epithelial tumor cell motility.
Topics: Animals; Cell Line; Cell Movement; Chemotaxis; Cytokines; Dogs; Dose-Response Relationship, Drug; Epithelium; Fibroblast Growth Factor 2; Hepatocyte Growth Factor; Humans; In Vitro Techniques; Interleukin-2; Interleukin-6; Macrophage Colony-Stimulating Factor; Neoplasm Invasiveness; Neoplasms; Rats; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 1991 |
Molecular analysis of MHC-class-I alterations in human tumor cell lines.
Topics: Antibodies, Monoclonal; Blotting, Northern; Cell Differentiation; Cell Line; Flow Cytometry; Fluorescent Antibody Technique; Genes, MHC Class I; Histocompatibility Antigens Class I; HLA-A Antigens; HLA-B Antigens; Humans; Interferon-gamma; Neoplasms; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
The in vitro development of cytotoxicity in response to granulocyte/macrophage-colony-stimulating factor or interferon gamma in the peripheral blood monocytes of patients with solid tumors: modulation by arachidonic acid metabolic inhibitors.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Cytotoxicity, Immunologic; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunity, Cellular; Indomethacin; Interferon-gamma; Leukocytes, Mononuclear; Leukotrienes; Lipoxygenase Inhibitors; Masoprocol; Middle Aged; Neoplasms; Oxygenases; Tetradecanoylphorbol Acetate | 1990 |
Chalones revisited--a possible role for transforming growth factor beta in tumour promotion.
Topics: Animals; Cell Differentiation; Cell Division; Growth Inhibitors; Humans; Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factors | 1990 |
Cytogenetic effects of phorbol ester tumor promoters: possible role in multistep tumorigenesis.
Topics: Chromosome Aberrations; Chromosomes; Chromosomes, Human; HeLa Cells; Humans; Neoplasms; Phorbol Esters; Tetradecanoylphorbol Acetate | 1990 |
Molecular cloning of cDNA for the catalytic subunit of rat liver type 2A protein phosphatase, and detection of high levels of expression of the gene in normal and cancer cells.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Cell Line, Transformed; Cloning, Molecular; DNA; Gene Expression Regulation; Humans; Liver; Male; Mice; Molecular Sequence Data; Neoplasms; Oncogenes; Phosphoprotein Phosphatases; Poly A; Rabbits; Rats; Rats, Inbred F344; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Modulation of in vitro antitumor immunity in response to the biological activators interleukin-2, gamma interferon, and granulocyte monocyte-colony stimulating factor in the peripheral blood of cancer patients receiving cytotoxic chemotherapy.
Topics: Adjuvants, Immunologic; Antineoplastic Agents; Colony-Stimulating Factors; Cytotoxicity Tests, Immunologic; Drug Synergism; Eicosanoids; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Immunity; In Vitro Techniques; Indomethacin; Interferon-gamma; Interleukin-2; Killer Cells, Lymphokine-Activated; Leukocytes, Mononuclear; Lymphocyte Activation; Monocytes; Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Reduction of interleukin 1 and interleukin 2 production by patients with advanced cancer.
Topics: Adult; Female; Humans; Immune Tolerance; Interleukin-1; Interleukin-2; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Middle Aged; Neoplasms; Phytohemagglutinins; Tetradecanoylphorbol Acetate | 1989 |
Isolation of functionally active pleural macrophages.
Topics: Cell Count; Cell Separation; Centrifugation, Density Gradient; Heart Failure; Humans; Hydrogen Peroxide; Macrophage Activation; Macrophages; Neoplasms; Pleural Effusion; Tetradecanoylphorbol Acetate | 1989 |
Transformation studies on human fibroblasts from familial polyposis coli patients and normal donors.
Topics: Adenomatous Polyposis Coli; Cell Division; Cell Transformation, Neoplastic; Fibroblasts; Humans; Kinetics; Methylnitronitrosoguanidine; Multiple Endocrine Neoplasia; Neoplasms; Skin; Tetradecanoylphorbol Acetate | 1988 |
Phorbol ester-induced loss of membrane sialic acid: implications for tumor cytolysis by natural killer cells.
Topics: Cell Membrane; Cytotoxicity, Immunologic; Freeze Fracturing; Humans; Killer Cells, Natural; N-Acetylneuraminic Acid; Neoplasms; Neuraminidase; Sialic Acids; Tetradecanoylphorbol Acetate | 1989 |
Lysis of tumor cells by human blood monocytes by a mechanism independent of activation of the oxidative burst.
Topics: Catalase; Cells, Cultured; Cytotoxicity, Immunologic; Granuloma; Humans; Hydrogen Peroxide; Interferon-gamma; Lymphokines; Macrophage-Activating Factors; Monocytes; Neoplasms; Oxygen; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Role of hydroxyl radical in neutrophil-mediated cytotoxicity.
Topics: Arachidonic Acid; Arachidonic Acids; Catechols; Cytotoxicity, Immunologic; Humans; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Masoprocol; Neoplasms; Neutrophils; Tetradecanoylphorbol Acetate | 1985 |
Ribosomal protein S6 phosphorylation and morphological changes in response to the tumour promoter 12-O-tetradecanoylphorbol 13-acetate in primary human tumour cells, established and transformed cell lines.
Topics: Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Fibroblasts; Glioma; Humans; Meningeal Neoplasms; Meningioma; Neoplasms; Phosphorylation; Ribosomal Proteins; Simian virus 40; Tetradecanoylphorbol Acetate | 1985 |
[The role of protein kinase C in cell surface signal transduction and tumor promotion].
Topics: Calcium; Cell Division; Drug Synergism; Extracellular Space; Humans; Neoplasms; Phosphatidylinositols; Protein Kinase C; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1986 |
The role of prostaglandin E1 in ornithine decarboxylase induction by tumor promoters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alprostadil; Animals; Diterpenes; Enzyme Induction; Female; Indomethacin; Mice; Mice, Inbred Strains; Models, Biological; Neoplasms; Ornithine Decarboxylase; Phorbols; Terpenes; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Phorbol-induced recruitment of lymphocytes for spontaneous cytolysis of natural killer-insensitive tumor targets.
Topics: Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Cell Membrane; Cytotoxicity, Immunologic; Fibroblasts; Freeze Fracturing; Humans; Killer Cells, Natural; Melanoma; Membrane Proteins; Microscopy, Electron; Neoplasms; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1986 |
Two distinct cytolytic mechanisms of macrophages and monocytes activated by phorbol myristate acetate.
Topics: Animals; Catalase; Cytotoxicity, Immunologic; Hydrogen Peroxide; Macrophage Activation; Macrophages; Monocytes; Neoplasms; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Swine; Tetradecanoylphorbol Acetate | 1988 |
Heterogeneity of the response to inducers of differentiation and to cytostatics of tumor cell populations.
Topics: Antineoplastic Agents; Cell Differentiation; Cisplatin; Cytarabine; Dacarbazine; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Doxorubicin; Fluorouracil; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Melanoma; Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1988 |
Role of a SER immune suppressor in immune surveillance.
Topics: Animals; Antibody Formation; Antigens, T-Independent; B-Lymphocytes; Dose-Response Relationship, Immunologic; Humans; Immunity, Cellular; Immunoglobulin G; Immunoglobulin M; Immunologic Surveillance; Killer Cells, Natural; Lymphocyte Activation; Mice; Neoplasms; Neutrophils; Phagocytosis; Suppressor Factors, Immunologic; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1988 |
Epidermal growth factor-induced mitogenesis in kidney epithelial cells (LLC-PK1).
Topics: Cells, Cultured; Epidermal Growth Factor; Epithelium; Kidney; Mitosis; Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
Early lymphocyte activation molecule defined by the monoclonal antibody MLR-3: biochemical and functional studies.
Topics: Antibodies, Monoclonal; Antigens, Surface; Cell Division; Cell Line; Chemical Phenomena; Chemistry; Humans; Kinetics; Lymphocyte Activation; Lymphocytes; Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1988 |
The transformed (initiated) human cell phenotype: study of cultured skin fibroblasts from individuals predisposed to cancer.
Topics: Actins; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Humans; Kirsten murine sarcoma virus; Moloney murine sarcoma virus; Neoplasms; Phenotype; Skin; Tetradecanoylphorbol Acetate | 1988 |
B-cell colony growth of malignant and normal B-cells.
Topics: B-Lymphocytes; Bromodeoxyuridine; Colony-Forming Units Assay; DNA; Humans; Interleukin-2; Leukemia, Hairy Cell; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Neoplasms; Phytohemagglutinins; Tetradecanoylphorbol Acetate | 1987 |
What is the role of environmental mutagens for human cancer development?
Topics: Amines; Animals; Carcinogens; Environmental Pollution; Enzyme Activation; Female; Humans; Male; Mutagenicity Tests; Mutagens; Mutation; Neoplasms; Polycyclic Compounds; Protein Kinase C; Rats; Rats, Inbred F344; Salmonella typhimurium; Tetradecanoylphorbol Acetate | 1986 |
Modification of luminol-dependent chemiluminescence reactivity of peripheral blood leukocytes from patients with lymphoreticular tumor, solid cancer, or healthy blood donors by interferon-alpha.
Topics: Adult; Aged; Aged, 80 and over; Female; Humans; In Vitro Techniques; Interferon Type I; Leukemia; Leukocytes; Luminescent Measurements; Luminol; Lymphoma; Male; Middle Aged; Neoplasms; Phagocytes; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Cancer and free radicals.
Topics: Animals; Carcinogens; DNA; DNA Damage; Free Radicals; Humans; Kinetics; Lipid Peroxides; Neoplasms; Proteins; Smoking; Tetradecanoylphorbol Acetate | 1986 |
Initiation and promotion in young and old animals. Implications for human tumour formation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Autopsy; Female; Humans; Mathematics; Mice; Models, Biological; Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
Enhancement of human growth hormone-stimulated mitogenesis of Nb2 node lymphoma cells by 12-O-tetradecanoyl-phorbol-13-acetate.
Topics: Animals; Cattle; Cell Cycle; Drug Synergism; Fetus; Growth Hormone; Humans; Lymph Nodes; Lymphatic Diseases; Lymphoma; Mitosis; Neoplasms; Osmolar Concentration; Phorbols; Prolactin; Sheep; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Tumor promotion and tumor progression.
Topics: Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; Humans; Mutation; Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
Retinoids and tumorigenesis: mechanistic considerations.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Fibroblasts; Humans; Mice; Neoplasms; Retinoids; Tetradecanoylphorbol Acetate; Vitamin A; Vitamin A Deficiency | 1985 |