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tetradecanoylphorbol acetate and Necrosis

tetradecanoylphorbol acetate has been researched along with Necrosis in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.70)18.7374
1990's10 (27.03)18.2507
2000's14 (37.84)29.6817
2010's11 (29.73)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Hobro, AJ; Kumanogoh, A; Lelliott, PM; Mizuno, Y; Nameki, S; Nishide, M; Obata, S; Okita, Y; Pavillon, N; Smith, NI; Yoshimura, H1
Cignarella, A; Lorkowski, S; Maeß, MB; Wittig, B1
Eriksson, P; Hellmark, T; Kurz, T; Motamedi, A; Segelmark, M; Söderberg, D1
Bao, YL; Huang, YX; Li, WL; Li, YX; Song, ZB; Sun, LG; Wang, Q; Yang, XG; Yu, CL; Zhang, WJ1
Cho, YC; Chung, N; Joo, YH; Lee, HS; Pak, PJ1
Deng, T; Ge, Y; Lu, M; Zhang, L; Zheng, X1
Belotto, MF; Curi, R; Hatanaka, E; Magdalon, J; Pithon-Curi, TC; Rodrigues, HG; Vinolo, MA1
Henrich, D; Marzi, I; Powerski, M; Sander, A; Teiler, A1
Bae, HS; Han, SI; Jeon, HM; Ju, MK; Kang, HS; Kim, CH; Lee, SY; Lim, SC; Park, HG1
Bíró, T; Czifra, G; Géczy, T; Oláh, A; Paus, R; Szabó, T; Szöllősi, AG; Tóth, BI; Zouboulis, CC1
Chamley, L; Chen, Q; Guo, F; Jin, HY; Lau, S; Stone, P1
Abbasi, A; Meyer, KC; Tsao, FH; Xiang, Z1
Jeon, HM; Ju, MK; Kang, HS; Kim, CH; Lee, SY; Park, HG1
Burvenich, C; Dosogne, H; Vangroenweghe, F1
Choi, EY; Choi, SC; Choi, SJ; Chun, CH; Chun, JS; Chung, YT; Han, WC; Jun, CD; Lee, HJ; Lee, HS; Lee, KM; Lee, MS; Oh, HM; Oh, JM; Seo, GS; Yeom, JJ1
Alefantis, T; Grant, C; Harhaj, E; Jain, P; Mostoller, K; Wigdahl, B1
Aubery, M; Bernard, M; Braut-Boucher, F; Bringuier, A; Derappe, C; Feldmann, G; Foglietti, MJ; Plantin-Carrenard, E; Vadrot, N1
Byun, HS; Hur, GM; Kwak, JY; Lee, ZW; Liu, ZG; Park, J; Park, KA; Piao, L; Seok, JH; Shin, S; Won, M; Yang, KJ1
Duong, HQ; Han, SI; Joo, YM; Kang, HS; Kim, CH; Kim, YJ; Lee, SY; Lim, SC; Moon, JY; Park, HG; Park, MJ; Yoo, MA; Youk, HS1
Chen, HC; Lin, LY; Tsai, JS; Yang, PM1
Ito, S; Kohno, M; Nakayama, K; Nakayama, M; Sato, T; Shirota, Y; Terawaki, H; Zhu, WJ1
Marsh, WH; Parsa, I; Sutton, AL1
Ankarcrona, M; Burkitt, M; Dypbukt, JM; Nicotera, P; Orrenius, S; Sjöholm, A; Ström, K1
Akagi, Y; Ito, K; Sawada, S1
Chapman, PB; Houghton, AN; Minasian, LM; Morrison, ME; Nathan, CF; Rosenblum, M; Steffens, T; Szatrowski, TP; Williams, L1
Araki, A; Ichinose, A; Sendo, F; Takei, H; Watanabe, H1
Martin, MU; Neumann, D; Zierke, M1
Beyaert, R; De Valck, D; Fiers, W; Vercammen, D1
Clément, MV; Pervaiz, S; Ponton, A1
Dietz, R; Haller, H; Li, PF; Maasch, C; von Harsdorf, R1
Boxer, LA; Gunning, WT; Keil, ML; Lachant, NA; Ochs, HD; Omann, GM; Rengan, R; Sweet, LI1
Fenech, M; Umegaki, K1
Morisco, C; Sadoshima, J; Seta, K; Vatner, SF; Yamamoto, S1
Borowitz, JL; Eybl, V; Gunasekar, P; Isom, GE; Li, L; Prabhakaran, K1
Kato, H; Namiki, H; Sakuma, Y; Suzuki, K1
Baguley, BC; Ching, LM; Gavin, JB; Thomsen, LL1
Alvarez, A; Boscá, L; Cascales, M; Diez Fernández, C; Martin-Sanz, P; Sanchez-Pérez, M1

Trials

1 trial(s) available for tetradecanoylphorbol acetate and Necrosis

ArticleYear
Hemorrhagic tumor necrosis during a pilot trial of tumor necrosis factor-alpha and anti-GD3 ganglioside monoclonal antibody in patients with metastatic melanoma.
    Blood, 1994, Jan-01, Volume: 83, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Female; Gangliosides; Humans; Male; Melanoma; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Necrosis; Neutrophils; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Lysis Syndrome; Tumor Necrosis Factor-alpha

1994

Other Studies

36 other study(ies) available for tetradecanoylphorbol acetate and Necrosis

ArticleYear
Single-cell Raman microscopy with machine learning highlights distinct biochemical features of neutrophil extracellular traps and necrosis.
    Scientific reports, 2023, 06-21, Volume: 13, Issue:1

    Topics: Extracellular Traps; Humans; Microscopy, Fluorescence; Necrosis; Neutrophils; Tetradecanoylphorbol Acetate

2023
Reduced PMA enhances the responsiveness of transfected THP-1 macrophages to polarizing stimuli.
    Journal of immunological methods, 2014, Jan-15, Volume: 402, Issue:1-2

    Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Apoptosis; CD11b Antigen; Cell Line; Cell Shape; Cell Survival; Chemokine CCL3; Dose-Response Relationship, Drug; Humans; Interferon-gamma; Interleukin-10; Interleukin-10 Receptor beta Subunit; Lipopolysaccharides; Macrophage Activation; Macrophages; Necrosis; Receptors, CCR7; RNA Interference; RNA, Small Interfering; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha; Up-Regulation

2014
Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission.
    Rheumatology (Oxford, England), 2015, Volume: 54, Issue:11

    Topics: Adrenal Cortex Hormones; Aged; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies, Antineutrophil Cytoplasmic; Biomarkers; Case-Control Studies; Cell Count; Cells, Cultured; Extracellular Traps; Female; Humans; In Vitro Techniques; Male; Middle Aged; Necrosis; Neutrophils; Octoxynol; Remission Induction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2015
Periplogenin induces necroptotic cell death through oxidative stress in HaCaT cells and ameliorates skin lesions in the TPA- and IMQ-induced psoriasis-like mouse models.
    Biochemical pharmacology, 2016, Apr-01, Volume: 105

    Topics: Aminoquinolines; Animals; Cell Death; Cell Line; Cell Survival; Digitoxigenin; Disease Models, Animal; Female; Humans; Imiquimod; Mice; Mice, Inbred BALB C; Necrosis; Oxidative Stress; Psoriasis; Tetradecanoylphorbol Acetate

2016
In vitro and in vivo comparison of the immunotoxicity of single- and multi-layered graphene oxides with or without pluronic F-127.
    Scientific reports, 2016, 12-12, Volume: 6

    Topics: Animals; Apoptosis; Chemokine CCL2; Cytochalasin D; Dose-Response Relationship, Drug; Graphite; Humans; Interleukin-1beta; Kidney; L-Lactate Dehydrogenase; Lung; Mice; Necrosis; Oxides; Phagocytosis; Poloxamer; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; THP-1 Cells; Transforming Growth Factor beta

2016
Redistribution of intracellular calcium and its effect on apoptosis in macrophages: Induction by oxidized LDL.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2009, Volume: 63, Issue:4

    Topics: Apoptosis; Calcium Signaling; Cell Differentiation; Culture Media, Serum-Free; Egtazic Acid; Humans; Lipoproteins, LDL; Macrophages; Membrane Potentials; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Necrosis; Tetradecanoylphorbol Acetate; Thapsigargin; U937 Cells

2009
Moderate exercise improves leucocyte function and decreases inflammation in diabetes.
    Clinical and experimental immunology, 2010, Volume: 162, Issue:2

    Topics: Animals; Apoptosis; C-Reactive Protein; Chemokines, CXC; Creatine Kinase; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Inflammation; Interleukins; L-Lactate Dehydrogenase; Leukocytes; Macrophages, Peritoneal; Male; Necrosis; Neutrophils; Peritoneal Cavity; Physical Conditioning, Animal; Rats; Rats, Wistar; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2010
In vitro manipulation of endothelial progenitor cell adhesion to vascular endothelium and extracellular matrix by the phorbol ester PMA.
    Artificial cells, blood substitutes, and immobilization biotechnology, 2011, Volume: 39, Issue:4

    Topics: Apoptosis; Biomarkers; Cell Adhesion; Cell Differentiation; Collagen; Dose-Response Relationship, Drug; Endothelium, Vascular; Extracellular Matrix; Fibronectins; Gene Expression Regulation; Humans; Laminin; Necrosis; Stem Cells; Tetradecanoylphorbol Acetate; Time Factors; Umbilical Veins

2011
Homeobox gene Dlx-2 is implicated in metabolic stress-induced necrosis.
    Molecular cancer, 2011, Sep-14, Volume: 10

    Topics: Antigens, Surface; Apoptosis; Breast Neoplasms; Cell Aggregation; Cell Line, Tumor; Colonic Neoplasms; Female; Gene Expression Profiling; Gene Knockdown Techniques; Glucose; Humans; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membranes; Necrosis; Neoplasms; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Permeability; Reactive Oxygen Species; RNA Interference; Stress, Physiological; Tetradecanoylphorbol Acetate

2011
Protein kinase C isoforms have differential roles in the regulation of human sebocyte biology.
    The Journal of investigative dermatology, 2012, Volume: 132, Issue:8

    Topics: Apoptosis; Cell Differentiation; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Silencing; Humans; Lipids; Necrosis; Protein Isoforms; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; RNA, Small Interfering; Sebaceous Glands; Tetradecanoylphorbol Acetate

2012
Phagocytosis of apoptotic trophoblastic debris protects endothelial cells against activation.
    Placenta, 2012, Volume: 33, Issue:7

    Topics: Apoptosis; Cell Line; Endothelial Cells; Female; Humans; Immune Tolerance; Interleukin-6; Lipopolysaccharides; Lung; Necrosis; Phagocytosis; Pregnancy; Tetradecanoylphorbol Acetate; Trophoblasts

2012
Neutrophil necrosis and annexin 1 degradation associated with airway inflammation in lung transplant recipients with cystic fibrosis.
    BMC pulmonary medicine, 2012, Aug-17, Volume: 12

    Topics: Actins; Annexin A1; Apoptosis; Biomarkers; Bronchitis; Bronchoalveolar Lavage; Case-Control Studies; Cell Survival; Cells, Cultured; Cystic Fibrosis; Humans; Lung Transplantation; Necrosis; Neutrophils; Tetradecanoylphorbol Acetate

2012
Early growth response 1 regulates glucose deprivation-induced necrosis.
    Oncology reports, 2013, Volume: 29, Issue:2

    Topics: Early Growth Response Protein 1; Gene Expression Profiling; Glucose; Hep G2 Cells; HMGB1 Protein; Humans; MCF-7 Cells; Necrosis; Plasmids; Reactive Oxygen Species; RNA, Small Interfering; Spheroids, Cellular; Tetradecanoylphorbol Acetate; Transfection

2013
Composition and milk cell characteristics in quarter milk fractions of dairy cows with low cell count.
    Veterinary journal (London, England : 1997), 2002, Volume: 164, Issue:3

    Topics: Animals; Apoptosis; Cattle; Cell Count; Cell Survival; Chlorides; Dairying; Fats; Female; Lactose; Milk; Milk Proteins; Necrosis; Neutrophils; Potassium; Respiratory Burst; Sodium; Temperature; Tetradecanoylphorbol Acetate

2002
Combined action of extracellular signal-regulated kinase and p38 kinase rescues Molt4 T cells from nitric oxide-induced apoptotic and necrotic cell death.
    Free radical biology & medicine, 2004, Aug-15, Volume: 37, Issue:4

    Topics: Apoptosis; Blotting, Western; Carcinogens; Caspase 3; Caspase 8; Caspases; Catalysis; Cell Line, Tumor; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Mitogen-Activated Protein Kinase 3; Necrosis; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Penicillamine; Phorbol Esters; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Pyridines; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Suppressor Protein p53

2004
Secretion of the human T cell leukemia virus type I transactivator protein tax.
    The Journal of biological chemistry, 2005, Apr-29, Volume: 280, Issue:17

    Topics: Animals; Apoptosis; Bacterial Proteins; Brefeldin A; Cell Culture Techniques; Cell Line; Cell Line, Tumor; Central Nervous System; Cricetinae; Culture Media; Cytoplasm; DNA, Complementary; Endoplasmic Reticulum; Enzyme-Linked Immunosorbent Assay; Gene Products, tax; Golgi Apparatus; Green Fluorescent Proteins; Humans; Interleukin-6; Ionomycin; Luminescent Proteins; Models, Biological; Necrosis; Neurodegenerative Diseases; Neurons; Plasmids; Protein Structure, Tertiary; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Transcriptional Activation; Transfection

2005
Differential responses of proliferative and non-proliferative leukemia cells to oxidative stress.
    Free radical research, 2005, Volume: 39, Issue:1

    Topics: Apoptosis; Caspase 3; Caspases; Cell Death; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Cysteine; Dose-Response Relationship, Drug; Glutathione; Glutathione Peroxidase; HL-60 Cells; Humans; Leukemia; Necrosis; Oxidative Stress; Oxygen; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Spectrometry, Fluorescence; Sulfhydryl Compounds; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Time Factors

2005
Phorbol 12-myristate 13-acetate protects against tumor necrosis factor (TNF)-induced necrotic cell death by modulating the recruitment of TNF receptor 1-associated death domain and receptor-interacting protein into the TNF receptor 1 signaling complex: Im
    Molecular pharmacology, 2006, Volume: 70, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Death; Cells, Cultured; Enzyme Activation; HeLa Cells; Humans; JNK Mitogen-Activated Protein Kinases; Mice; Necrosis; NF-kappa B; Nuclear Proteins; Nuclear Receptor Interacting Protein 1; Poly(ADP-ribose) Polymerases; Protein Kinase C; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; Tetradecanoylphorbol Acetate; TNF Receptor-Associated Death Domain Protein; Tumor Necrosis Factor Receptor-Associated Peptides and Proteins; Tumor Necrosis Factor-alpha

2006
Protein kinase C-ERK1/2 signal pathway switches glucose depletion-induced necrosis to apoptosis by regulating superoxide dismutases and suppressing reactive oxygen species production in A549 lung cancer cells.
    Journal of cellular physiology, 2007, Volume: 211, Issue:2

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Apoptosis Inducing Factor; Caspase 3; Caspase 9; Catalase; Cell Line, Tumor; Cell Survival; Endodeoxyribonucleases; Enzyme Activation; Enzyme Induction; Enzyme Stability; Extracellular Signal-Regulated MAP Kinases; Glucose; HMGB1 Protein; Humans; Lung Neoplasms; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Necrosis; Protein Kinase C; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Time Factors

2007
Cadmium induces Ca2+-dependent necrotic cell death through calpain-triggered mitochondrial depolarization and reactive oxygen species-mediated inhibition of nuclear factor-kappaB activity.
    Chemical research in toxicology, 2007, Volume: 20, Issue:3

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Blotting, Western; Cadmium; Calcium; Calpain; Caspase 3; Cell Death; CHO Cells; Cricetinae; Cricetulus; DNA; DNA Fragmentation; Genes, Reporter; Membrane Potentials; Mitochondrial Membranes; Necrosis; NF-kappa B; Plasmids; Reactive Oxygen Species; Tetradecanoylphorbol Acetate

2007
Polymorphonuclear leukocyte injury by methylglyoxal and hydrogen peroxide: a possible pathological role for enhanced oxidative stress in chronic kidney disease.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:10

    Topics: Apoptosis; Cell Survival; Drug Synergism; Free Radicals; Humans; Hydrogen Peroxide; In Vitro Techniques; Kidney Failure, Chronic; Luminescent Measurements; Necrosis; Neutrophils; Oxidative Stress; Pyruvaldehyde; Respiratory Burst; Tetradecanoylphorbol Acetate

2008
An in vitro model of pancreas carcinogenesis: two-stage MNU--TPA effect.
    The American journal of pathology, 1980, Volume: 98, Issue:3

    Topics: Animals; Cell Transformation, Neoplastic; Hyperplasia; Methylnitrosourea; Mice; Mice, Nude; Models, Biological; Necrosis; Neoplasm Transplantation; Nitrosourea Compounds; Organ Culture Techniques; Pancreas; Pancreatic Neoplasms; Phorbols; Rats; Tetradecanoylphorbol Acetate; Transplantation, Heterologous

1980
Different prooxidant levels stimulate growth, trigger apoptosis, or produce necrosis of insulin-secreting RINm5F cells. The role of intracellular polyamines.
    The Journal of biological chemistry, 1994, Dec-02, Volume: 269, Issue:48

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenosylmethionine Decarboxylase; Animals; Apoptosis; Cell Division; Cell Line; Cell Survival; Deoxyguanosine; Dose-Response Relationship, Drug; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Naphthoquinones; Necrosis; Oxidants; Polyamines; Tetradecanoylphorbol Acetate; Time Factors

1994
Radiation-induced apoptosis and necrosis in Molt-4 cells: a study of dose-effect relationships and their modification.
    International journal of radiation biology, 1993, Volume: 64, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bromodeoxyuridine; Cell Death; Cycloheximide; Isoquinolines; Leukemia, Lymphoid; Necrosis; Piperazines; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured

1993
Rapid killing of human neutrophils by the potent activator phorbol 12-myristate 13-acetate (PMA) accompanied by changes different from typical apoptosis or necrosis.
    Journal of leukocyte biology, 1996, Volume: 59, Issue:2

    Topics: Antioxidants; Apoptosis; Cell Death; Cell Membrane Permeability; Cell Survival; DNA; Enzyme Inhibitors; Humans; Microscopy, Electron; Necrosis; Neutrophils; Phagocytosis; Protein Kinase C; Tetradecanoylphorbol Acetate

1996
Withdrawal of 2-mercaptoethanol induces apoptosis in a B-cell line via Fas upregulation.
    Journal of cellular physiology, 1998, Volume: 177, Issue:1

    Topics: Animals; Apoptosis; B-Lymphocytes; Carcinogens; Cell Cycle; Cells, Cultured; Culture Media; Fas Ligand Protein; fas Receptor; Gene Expression; Ionomycin; Ionophores; Membrane Glycoproteins; Mercaptoethanol; Mice; Necrosis; Proto-Oncogene Mas; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate

1998
Differential activation of phospholipases during necrosis or apoptosis: a comparative study using tumor necrosis factor and anti-Fas antibodies.
    Journal of cellular biochemistry, 1998, Dec-01, Volume: 71, Issue:3

    Topics: Animals; Antibodies; Apoptosis; Arachidonic Acid; Calcimycin; Cell Cycle; Enzyme Activation; fas Receptor; Glycerophospholipids; Humans; Mice; Necrosis; Phospholipase D; Phospholipases; Phospholipases A; Phospholipases A2; Phosphorylation; Ploidies; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1998
Apoptosis induced by hydrogen peroxide is mediated by decreased superoxide anion concentration and reduction of intracellular milieu.
    FEBS letters, 1998, Nov-27, Volume: 440, Issue:1-2

    Topics: Apoptosis; Blotting, Western; Caspase Inhibitors; Caspases; Dose-Response Relationship, Drug; Enzyme Activation; Fluoresceins; Glutathione; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Melanoma; NADH, NADPH Oxidoreductases; Necrosis; Oxidation-Reduction; Poly(ADP-ribose) Polymerases; RNA, Antisense; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

1998
Requirement for protein kinase C in reactive oxygen species-induced apoptosis of vascular smooth muscle cells.
    Circulation, 1999, Aug-31, Volume: 100, Issue:9

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apoptosis; Cells, Cultured; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Hydrogen Peroxide; Immunohistochemistry; In Situ Nick-End Labeling; Muscle, Smooth, Vascular; Naphthalenes; Necrosis; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Reactive Oxygen Species; Staurosporine; Tetradecanoylphorbol Acetate

1999
Actin cytoskeletal function is spared, but apoptosis is increased, in WAS patient hematopoietic cells.
    Blood, 2000, Feb-15, Volume: 95, Issue:4

    Topics: Actins; Adenosine Diphosphate; Apoptosis; Blood Platelets; Cell Survival; Cytochalasin B; Cytoskeleton; Dinoprost; fas Receptor; Humans; In Vitro Techniques; Kinetics; Leukocytes; Lymphocytes; Mutation, Missense; N-Formylmethionine Leucyl-Phenylalanine; Necrosis; Point Mutation; Proteins; Reference Values; src Homology Domains; Tetradecanoylphorbol Acetate; Thrombocytopenia; Wiskott-Aldrich Syndrome; Wiskott-Aldrich Syndrome Protein

2000
Cytokinesis-block micronucleus assay in WIL2-NS cells: a sensitive system to detect chromosomal damage induced by reactive oxygen species and activated human neutrophils.
    Mutagenesis, 2000, Volume: 15, Issue:3

    Topics: B-Lymphocytes; Cell Division; Cell Line; HL-60 Cells; Humans; Hydrogen Peroxide; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Necrosis; Neutrophil Activation; Neutrophils; Reactive Oxygen Species; Sensitivity and Specificity; Superoxides; Tetradecanoylphorbol Acetate

2000
Chelerythrine rapidly induces apoptosis through generation of reactive oxygen species in cardiac myocytes.
    Journal of molecular and cellular cardiology, 2001, Volume: 33, Issue:10

    Topics: Acetylcysteine; Adenoviridae; Alkaloids; Animals; Animals, Newborn; Annexin A5; Antioxidants; Apoptosis; Benzophenanthridines; Caspases; Cytosol; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Genetic Vectors; Glutathione; Hydrogen Peroxide; Immunoblotting; In Situ Nick-End Labeling; Injections, Intravenous; Microscopy, Fluorescence; Myocardium; Necrosis; Phenanthridines; Protein Isoforms; Protein Kinase C; Rats; Rats, Wistar; Reactive Oxygen Species; Staurosporine; Subcellular Fractions; Tetradecanoylphorbol Acetate; Time Factors

2001
Mechanisms of the apoptotic and necrotic actions of trimethyltin in cerebellar granule cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 64, Issue:1

    Topics: Alkaloids; Animals; Apoptosis; Benzophenanthridines; Catalase; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Necrosis; Neurons; NG-Nitroarginine Methyl Ester; Nitrites; Phenanthridines; Protein Kinase C; Rats; Reactive Oxygen Species; Receptors, Glutamate; Tetradecanoylphorbol Acetate; Thiobarbituric Acid Reactive Substances; Trimethyltin Compounds

2001
Hemopexins suppress phorbol ester-induced necrosis of polymorphonuclear leucocytes.
    Cell structure and function, 2001, Volume: 26, Issue:4

    Topics: Animals; Antineoplastic Agents; Cattle; Cell Survival; Dose-Response Relationship, Drug; Hemopexin; Humans; Necrosis; Neutrophils; Serum Albumin; Superoxides; Swine; Tetradecanoylphorbol Acetate; Ultrafiltration

2001
Modulation of superoxide production from murine macrophages by the antitumour agent flavone acetic acid and xanthenone acetic acid analogues.
    Biochemical pharmacology, 1992, Jan-22, Volume: 43, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Flavonoids; Macrophages; Mice; Mice, Inbred C3H; Necrosis; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Xanthenes

1992
Isoenzymes of carbohydrate metabolism in primary cultures of hepatocytes from thioacetamide-induced rat liver necrosis: responses to growth factors.
    Hepatology (Baltimore, Md.), 1992, Volume: 16, Issue:1

    Topics: Animals; Bombesin; Carbohydrate Metabolism; Cells, Cultured; Fetus; Fructosediphosphates; Glucagon; Growth Substances; Insulin; Isoenzymes; Liver; Liver Glycogen; Male; Necrosis; Phosphofructokinase-2; Phosphorylase a; Phosphotransferases; Protein Kinases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thioacetamide

1992